CompaRNA - on-line benchmarks of RNA structure prediction methods

Laboratory of Structural Bioinformatics @ Adam Mickiewicz University in Poznan

Home

Methods

Datasets

Rankings

RNA 2D Atlas

Help

FAQ

Contact us

RSS feeds

Twitter

Overview

Metric	PETfold_pre2.0(20)		CentroidFold
MCC	0.730	>	0.492
Average MCC ± 95% Confidence Intervals	0.732 ± 0.030	>	0.493 ± 0.028
Sensitivity	0.700	>	0.430
Positive Predictive Value	0.762	>	0.563
Total TP	25486	>	15655
Total TN	102210058	<	102215715
Total FP	10832	<	14303
Total FP CONTRA	1342	<	1836
Total FP INCONS	6627	<	10307
Total FP COMP	2863	>	2160
Total FN	10944	<	20775
P-value	3.56938820447e-08

^top

Performance plots

Comparison of performance of PETfold_pre2.0(20) and CentroidFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and CentroidFold).
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for PETfold_pre2.0(20) and CentroidFold).
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and CentroidFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and CentroidFold).

^top

Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP	25486
Total TN	102210058
Total FP	10832
Total FP CONTRA	1342
Total FP INCONS	6627
Total FP COMP	2863
Total FN	10944

Total Scores
MCC	0.730
Average MCC ± 95% Confidence Intervals	0.732 ± 0.030
Sensitivity	0.700
Positive Predictive Value	0.762
Nr of predictions	76

^top

2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
CRW_00024	SSU_rRNA_archaea links to Rfam database...	0.89	0.88	0.90	404	1085151	82	10	36	36	54
CRW_00034	SSU_rRNA_bacteria links to Rfam database...	0.82	0.79	0.85	374	1141875	86	17	50	19	100
CRW_00048	SSU_rRNA_bacteria links to Rfam database...	0.84	0.83	0.84	390	1170753	91	18	54	19	80
CRW_00054	SSU_rRNA_bacteria links to Rfam database...	0.84	0.84	0.84	381	1107361	95	17	57	21	75
CRW_00059	SSU_rRNA_bacteria links to Rfam database...	0.84	0.82	0.85	390	1172289	85	17	50	18	83
CRW_00061	SSU_rRNA_bacteria links to Rfam database...	0.84	0.82	0.86	390	1181501	85	16	46	23	86
CRW_00068	SSU_rRNA_bacteria links to Rfam database...	0.84	0.84	0.84	383	1108851	87	16	55	16	74
CRW_00096	SSU_rRNA_bacteria links to Rfam database...	0.85	0.83	0.87	388	1178436	81	12	44	25	77
CRW_00140	SSU_rRNA_bacteria links to Rfam database...	0.85	0.84	0.86	388	1135827	85	15	48	22	75
CRW_00141	SSU_rRNA_bacteria links to Rfam database...	0.83	0.81	0.85	387	1201568	90	18	52	20	89
CRW_00150	SSU_rRNA_bacteria links to Rfam database...	0.83	0.82	0.85	381	1152473	90	16	51	23	85
CRW_00152	SSU_rRNA_bacteria links to Rfam database...	0.83	0.81	0.85	381	1179968	89	17	50	22	90
CRW_00166	SSU_rRNA_bacteria links to Rfam database...	0.85	0.83	0.86	387	1190748	90	11	50	29	81
CRW_00173	SSU_rRNA_bacteria links to Rfam database...	0.80	0.80	0.81	354	1082220	107	18	64	25	91
CRW_00177	SSU_rRNA_bacteria links to Rfam database...	0.82	0.81	0.84	382	1178424	101	17	57	27	91
CRW_00196	SSU_rRNA_bacteria links to Rfam database...	0.83	0.81	0.85	387	1207780	91	16	52	23	88
CRW_00230	SSU_rRNA_bacteria links to Rfam database...	0.85	0.82	0.87	394	1198472	81	16	44	21	84
CRW_00245	SSU_rRNA_bacteria links to Rfam database...	0.87	0.86	0.87	390	1105881	79	17	40	22	63
CRW_00248	SSU_rRNA_bacteria links to Rfam database...	0.84	0.82	0.87	396	1218684	87	15	46	26	88
CRW_00250	SSU_rRNA_bacteria links to Rfam database...	0.83	0.80	0.85	382	1198478	88	15	51	22	96
CRW_00256	SSU_rRNA_bacteria links to Rfam database...	0.83	0.81	0.85	379	1192296	87	16	49	22	89
CRW_00270	SSU_rRNA_bacteria links to Rfam database...	0.86	0.86	0.86	390	1111833	85	15	48	22	65
CRW_00271	SSU_rRNA_bacteria links to Rfam database...	0.82	0.81	0.84	375	1122302	98	14	60	24	87
CRW_00273	SSU_rRNA_bacteria links to Rfam database...	0.84	0.84	0.84	375	1085156	94	14	56	24	71
CRW_00275	SSU_rRNA_bacteria links to Rfam database...	0.86	0.86	0.87	391	1114821	86	15	44	27	66
CRW_00277	SSU_rRNA_bacteria links to Rfam database...	0.84	0.84	0.85	379	1110348	89	16	52	21	74
CRW_00278	SSU_rRNA_bacteria links to Rfam database...	0.84	0.82	0.86	371	1129827	85	12	46	27	79
CRW_00279	SSU_rRNA_bacteria links to Rfam database...	0.82	0.81	0.84	377	1179965	98	18	56	24	87
CRW_00280	SSU_rRNA_bacteria links to Rfam database...	0.85	0.85	0.86	384	1117811	93	15	50	28	69
CRW_00281	SSU_rRNA_bacteria links to Rfam database...	0.84	0.82	0.85	381	1144895	89	14	51	24	83
CRW_00284	SSU_rRNA_bacteria links to Rfam database...	0.84	0.82	0.85	376	1131317	94	16	51	27	80
CRW_00285	SSU_rRNA_bacteria links to Rfam database...	0.84	0.83	0.86	380	1117816	91	17	47	27	78
CRW_00289	SSU_rRNA_bacteria links to Rfam database...	0.83	0.81	0.85	386	1189199	95	13	55	27	90
CRW_00298	SSU_rRNA_eukarya links to Rfam database...	0.58	0.54	0.63	267	1620473	212	31	129	52	227
CRW_00301	SSU_rRNA_eukarya links to Rfam database...	0.49	0.46	0.53	240	1762048	265	37	178	50	279
CRW_00306	SSU_rRNA_eukarya links to Rfam database...	0.60	0.57	0.63	263	1445430	208	26	131	51	199
CRW_00310	SSU_rRNA_eukarya links to Rfam database...	0.55	0.51	0.59	264	1805500	238	32	154	52	257
CRW_00326	SSU_rRNA_eukarya links to Rfam database...	0.64	0.60	0.68	299	1627669	193	22	120	51	203
CRW_00330	SSU_rRNA_eukarya links to Rfam database...	0.55	0.51	0.60	262	1988577	231	26	150	55	255
CRW_00332	SSU_rRNA_eukarya links to Rfam database...	0.51	0.48	0.56	227	1769613	237	20	161	56	250
CRW_00333	SSU_rRNA_eukarya links to Rfam database...	0.48	0.43	0.53	220	1892069	260	36	160	64	294
CRW_00345	SSU_rRNA_eukarya links to Rfam database...	0.56	0.53	0.60	262	1586434	224	28	147	49	236
CRW_00346	SSU_rRNA_eukarya links to Rfam database...	0.59	0.55	0.63	278	1584648	213	32	132	49	223
CRW_00348	SSU_rRNA_eukarya links to Rfam database...	0.58	0.54	0.61	272	1615059	225	29	143	53	231
CRW_00358	SSU_rRNA_eukarya links to Rfam database...	0.56	0.53	0.60	269	1674914	228	29	153	46	238
CRW_00366	SSU_rRNA_eukarya links to Rfam database...	0.60	0.56	0.64	269	1579331	210	25	128	57	213
CRW_00370	SSU_rRNA_eukarya links to Rfam database...	0.60	0.57	0.64	288	1640315	211	20	143	48	218
CRW_00371	SSU_rRNA_eukarya links to Rfam database...	0.58	0.55	0.60	275	1611455	232	17	163	52	221
CRW_00372	SSU_rRNA_eukarya links to Rfam database...	0.59	0.55	0.62	275	1625865	212	23	143	46	223
CRW_00386	SSU_rRNA_eukarya links to Rfam database...	0.49	0.46	0.53	236	1750812	258	28	180	50	279
CRW_00403	SSU_rRNA_eukarya links to Rfam database...	0.53	0.52	0.54	240	1606084	283	31	173	79	224
CRW_00411	SSU_rRNA_eukarya links to Rfam database...	0.58	0.54	0.61	269	1615064	222	21	149	52	227
CRW_00414	SSU_rRNA_eukarya links to Rfam database...	0.57	0.53	0.62	263	1665801	210	25	136	49	232
CRW_00466	SSU_rRNA_bacteria links to Rfam database...	0.85	0.85	0.85	388	1116310	90	13	54	23	70
CRW_00589	SSU_rRNA_bacteria links to Rfam database...	0.84	0.82	0.86	367	1094034	98	8	51	39	78
CRW_00590	SSU_rRNA_bacteria links to Rfam database...	0.87	0.84	0.89	381	1119329	87	4	42	41	71
CRW_00591	SSU_rRNA_bacteria links to Rfam database...	0.85	0.84	0.86	373	1098469	103	7	54	42	73
CRW_00598	SSU_rRNA_eukarya links to Rfam database...	0.54	0.51	0.58	250	1665793	234	28	154	52	241
CRW_00758	SSU_rRNA_eukarya links to Rfam database...	0.57	0.54	0.61	263	1640333	241	27	143	71	220
CRW_00759	SSU_rRNA_eukarya links to Rfam database...	0.56	0.53	0.59	254	1636715	232	18	158	56	227
CRW_00760	SSU_rRNA_eukarya links to Rfam database...	0.53	0.49	0.57	239	1638533	247	16	167	64	247
CRW_00772	SSU_rRNA_bacteria links to Rfam database...	0.78	0.76	0.80	306	945618	127	7	69	51	98
CRW_00789	SSU_rRNA_bacteria links to Rfam database...	0.82	0.80	0.85	357	1137365	108	8	56	44	90
CRW_00795	SSU_rRNA_bacteria links to Rfam database...	0.79	0.76	0.82	301	1152552	149	5	63	81	93
CRW_00849	SSU_rRNA_bacteria links to Rfam database...	0.80	0.78	0.82	366	1117816	101	14	64	23	104
CRW_00997	SSU_rRNA_bacteria links to Rfam database...	0.85	0.84	0.85	389	1135822	85	16	51	18	75
CRW_01153	SSU_rRNA_eukarya links to Rfam database...	0.59	0.56	0.63	283	1606076	220	25	144	51	220
CRW_01171	SSU_rRNA_eukarya links to Rfam database...	0.52	0.48	0.56	245	1593566	240	31	163	46	261
CRW_01300	SSU_rRNA_eukarya links to Rfam database...	0.60	0.55	0.67	283	1693295	193	17	125	51	232
PDB_00703	SSU_rRNA_bacteria links to Rfam database...	0.78	0.72	0.84	355	1073423	101	6	61	34	140
PDB_00854	SSU_rRNA_bacteria links to Rfam database...	0.75	0.68	0.84	363	1500344	118	10	61	47	172
PDB_01088	SSU_rRNA_bacteria links to Rfam database...	0.74	0.65	0.83	357	1471042	115	5	66	44	190
PDB_01103	SSU_rRNA_bacteria links to Rfam database...	0.75	0.66	0.85	373	1606088	99	8	59	32	189
PDB_01105	SSU_rRNA_bacteria links to Rfam database...	0.75	0.68	0.84	366	1433533	107	4	68	35	174
PDB_01120	SSU_rRNA_bacteria links to Rfam database...	0.78	0.72	0.85	378	1204681	101	9	60	32	149
PDB_01273	SSU_rRNA_bacteria links to Rfam database...	0.78	0.73	0.84	358	1117834	110	9	59	42	133

^top

Performance of CentroidFold - scored lower in this pairwise comparison

1. Total counts & total scores for CentroidFold

Total Base Pair Counts
Total TP	15655
Total TN	102215715
Total FP	14303
Total FP CONTRA	1836
Total FP INCONS	10307
Total FP COMP	2160
Total FN	20775

Total Scores
MCC	0.492
Average MCC ± 95% Confidence Intervals	0.493 ± 0.028
Sensitivity	0.430
Positive Predictive Value	0.563
Nr of predictions	76

^top

2. Individual counts for CentroidFold [ download as .csv ]

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
CRW_00024	SSU_rRNA_archaea links to Rfam database...	0.79	0.76	0.83	347	1085183	108	8	63	37	111
CRW_00034	SSU_rRNA_bacteria links to Rfam database...	0.68	0.66	0.71	312	1141875	159	19	110	30	162
CRW_00048	SSU_rRNA_bacteria links to Rfam database...	0.60	0.49	0.75	230	1170907	91	8	70	13	240
CRW_00054	SSU_rRNA_bacteria links to Rfam database...	0.56	0.49	0.64	223	1107466	140	16	111	13	233
CRW_00059	SSU_rRNA_bacteria links to Rfam database...	0.60	0.51	0.71	241	1172408	111	9	88	14	232
CRW_00061	SSU_rRNA_bacteria links to Rfam database...	0.64	0.57	0.72	269	1181581	110	23	80	7	207
CRW_00068	SSU_rRNA_bacteria links to Rfam database...	0.55	0.49	0.63	225	1108945	147	19	116	12	232
CRW_00096	SSU_rRNA_bacteria links to Rfam database...	0.56	0.49	0.63	228	1178519	155	15	118	22	237
CRW_00140	SSU_rRNA_bacteria links to Rfam database...	0.59	0.49	0.70	226	1135957	106	11	84	11	237
CRW_00141	SSU_rRNA_bacteria links to Rfam database...	0.63	0.56	0.70	268	1201642	136	16	99	21	208
CRW_00150	SSU_rRNA_bacteria links to Rfam database...	0.55	0.47	0.66	217	1152591	126	17	96	13	249
CRW_00152	SSU_rRNA_bacteria links to Rfam database...	0.51	0.42	0.62	200	1180095	129	14	107	8	271
CRW_00166	SSU_rRNA_bacteria links to Rfam database...	0.61	0.53	0.70	247	1190845	120	6	98	16	221
CRW_00173	SSU_rRNA_bacteria links to Rfam database...	0.35	0.31	0.39	139	1082299	226	23	195	8	306
CRW_00177	SSU_rRNA_bacteria links to Rfam database...	0.52	0.45	0.59	213	1178522	162	17	128	17	260
CRW_00196	SSU_rRNA_bacteria links to Rfam database...	0.59	0.52	0.67	247	1207869	131	18	101	12	228
CRW_00230	SSU_rRNA_bacteria links to Rfam database...	0.59	0.52	0.67	250	1198552	140	19	105	16	228
CRW_00245	SSU_rRNA_bacteria links to Rfam database...	0.56	0.49	0.65	221	1105989	128	13	105	10	232
CRW_00248	SSU_rRNA_bacteria links to Rfam database...	0.66	0.61	0.71	296	1218724	154	20	101	33	188
CRW_00250	SSU_rRNA_bacteria links to Rfam database...	0.57	0.50	0.66	237	1198568	130	20	101	9	241
CRW_00256	SSU_rRNA_bacteria links to Rfam database...	0.45	0.35	0.57	165	1192449	145	20	106	19	303
CRW_00270	SSU_rRNA_bacteria links to Rfam database...	0.67	0.57	0.79	260	1111955	83	11	60	12	195
CRW_00271	SSU_rRNA_bacteria links to Rfam database...	0.48	0.41	0.55	190	1122405	171	26	130	15	272
CRW_00273	SSU_rRNA_bacteria links to Rfam database...	0.51	0.43	0.60	194	1085280	142	14	113	15	252
CRW_00275	SSU_rRNA_bacteria links to Rfam database...	0.62	0.54	0.70	249	1114913	130	13	96	21	208
CRW_00277	SSU_rRNA_bacteria links to Rfam database...	0.48	0.36	0.64	165	1110536	105	15	79	11	288
CRW_00278	SSU_rRNA_bacteria links to Rfam database...	0.49	0.41	0.57	186	1129931	157	13	126	18	264
CRW_00279	SSU_rRNA_bacteria links to Rfam database...	0.54	0.45	0.64	209	1180088	132	19	100	13	255
CRW_00280	SSU_rRNA_bacteria links to Rfam database...	0.53	0.42	0.67	192	1117973	105	9	86	10	261
CRW_00281	SSU_rRNA_bacteria links to Rfam database...	0.62	0.57	0.68	265	1144950	146	18	108	20	199
CRW_00284	SSU_rRNA_bacteria links to Rfam database...	0.48	0.36	0.65	162	1131511	101	11	76	14	294
CRW_00285	SSU_rRNA_bacteria links to Rfam database...	0.67	0.59	0.76	268	1117909	98	16	67	15	190
CRW_00289	SSU_rRNA_bacteria links to Rfam database...	0.61	0.55	0.68	260	1189270	143	18	105	20	216
CRW_00298	SSU_rRNA_eukarya links to Rfam database...	0.25	0.22	0.28	109	1620517	295	50	224	21	385
CRW_00301	SSU_rRNA_eukarya links to Rfam database...	0.48	0.39	0.58	203	1762152	211	28	120	63	316
CRW_00306	SSU_rRNA_eukarya links to Rfam database...	0.29	0.26	0.32	120	1445480	309	50	200	59	342
CRW_00310	SSU_rRNA_eukarya links to Rfam database...	0.38	0.34	0.42	178	1805524	303	44	204	55	343
CRW_00326	SSU_rRNA_eukarya links to Rfam database...	0.57	0.48	0.67	240	1627752	163	19	99	45	262
CRW_00330	SSU_rRNA_eukarya links to Rfam database...	0.30	0.25	0.36	131	1988654	302	33	197	72	386
CRW_00332	SSU_rRNA_eukarya links to Rfam database...	0.25	0.22	0.28	104	1769656	299	47	214	38	373
CRW_00333	SSU_rRNA_eukarya links to Rfam database...	0.30	0.24	0.36	125	1892139	288	29	192	67	389
CRW_00345	SSU_rRNA_eukarya links to Rfam database...	0.41	0.37	0.45	186	1586456	267	40	189	38	312
CRW_00346	SSU_rRNA_eukarya links to Rfam database...	0.40	0.38	0.42	189	1584645	289	48	208	33	312
CRW_00348	SSU_rRNA_eukarya links to Rfam database...	0.37	0.31	0.44	157	1615148	235	27	171	37	346
CRW_00358	SSU_rRNA_eukarya links to Rfam database...	0.42	0.39	0.45	200	1674917	285	39	209	37	307
CRW_00366	SSU_rRNA_eukarya links to Rfam database...	0.34	0.31	0.38	150	1579355	289	44	204	41	332
CRW_00370	SSU_rRNA_eukarya links to Rfam database...	0.38	0.33	0.43	167	1640375	256	43	181	32	339
CRW_00371	SSU_rRNA_eukarya links to Rfam database...	0.47	0.39	0.56	194	1611562	196	29	125	42	302
CRW_00372	SSU_rRNA_eukarya links to Rfam database...	0.48	0.41	0.58	202	1625955	204	26	123	55	296
CRW_00386	SSU_rRNA_eukarya links to Rfam database...	0.32	0.30	0.34	156	1750800	337	47	253	37	359
CRW_00403	SSU_rRNA_eukarya links to Rfam database...	0.31	0.29	0.34	135	1606132	324	52	209	63	329
CRW_00411	SSU_rRNA_eukarya links to Rfam database...	0.42	0.35	0.49	173	1615153	226	27	150	49	323
CRW_00414	SSU_rRNA_eukarya links to Rfam database...	0.42	0.36	0.48	180	1665851	239	34	160	45	315
CRW_00466	SSU_rRNA_bacteria links to Rfam database...	0.71	0.64	0.79	292	1116394	100	14	65	21	166
CRW_00589	SSU_rRNA_bacteria links to Rfam database...	0.34	0.28	0.42	125	1094162	188	16	157	15	320
CRW_00590	SSU_rRNA_bacteria links to Rfam database...	0.37	0.32	0.43	143	1119420	207	36	157	14	309
CRW_00591	SSU_rRNA_bacteria links to Rfam database...	0.65	0.59	0.72	261	1098541	124	19	82	23	185
CRW_00598	SSU_rRNA_eukarya links to Rfam database...	0.40	0.37	0.45	180	1665823	270	42	180	48	311
CRW_00758	SSU_rRNA_eukarya links to Rfam database...	0.37	0.34	0.40	164	1640353	298	41	208	49	319
CRW_00759	SSU_rRNA_eukarya links to Rfam database...	0.34	0.28	0.42	134	1636828	232	34	149	49	347
CRW_00760	SSU_rRNA_eukarya links to Rfam database...	0.38	0.34	0.42	167	1638559	278	50	179	49	319
CRW_00772	SSU_rRNA_bacteria links to Rfam database...	0.38	0.30	0.50	120	945758	137	16	106	15	284
CRW_00789	SSU_rRNA_bacteria links to Rfam database...	0.51	0.40	0.65	179	1137510	120	5	92	23	268
CRW_00795	SSU_rRNA_bacteria links to Rfam database...	0.35	0.28	0.44	110	1152672	173	15	124	34	284
CRW_00849	SSU_rRNA_bacteria links to Rfam database...	0.59	0.56	0.62	265	1117830	190	14	151	25	205
CRW_00997	SSU_rRNA_bacteria links to Rfam database...	0.63	0.55	0.72	256	1135921	119	15	86	18	208
CRW_01153	SSU_rRNA_eukarya links to Rfam database...	0.41	0.37	0.45	185	1606114	268	39	190	39	318
CRW_01171	SSU_rRNA_eukarya links to Rfam database...	0.46	0.41	0.52	206	1593608	228	40	151	37	300
CRW_01300	SSU_rRNA_eukarya links to Rfam database...	0.41	0.37	0.45	192	1693289	291	56	183	52	323
PDB_00703	SSU_rRNA_bacteria links to Rfam database...	0.55	0.49	0.61	244	1073448	180	13	140	27	251
PDB_00854	SSU_rRNA_bacteria links to Rfam database...	0.53	0.49	0.57	264	1500316	234	15	183	36	271
PDB_01088	SSU_rRNA_bacteria links to Rfam database...	0.46	0.39	0.55	215	1471076	203	25	154	24	332
PDB_01103	SSU_rRNA_bacteria links to Rfam database...	0.57	0.53	0.61	297	1606045	214	20	166	28	265
PDB_01105	SSU_rRNA_bacteria links to Rfam database...	0.62	0.57	0.68	307	1433517	177	8	139	30	233
PDB_01120	SSU_rRNA_bacteria links to Rfam database...	0.49	0.42	0.59	220	1204752	177	19	137	21	307
PDB_01273	SSU_rRNA_bacteria links to Rfam database...	0.51	0.47	0.56	229	1117849	211	14	168	29	262

^top

Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.

Table of contents:

Overview

Performance plots

Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

Performance of CentroidFold - scored lower in this pairwise comparison

1. Total counts & total scores for CentroidFold

2. Individual counts for CentroidFold [ download as .csv ]