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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) Carnac(seed)
MCC 0.894 > 0.729
Average MCC ± 95% Confidence Intervals 0.894 ± > 0.729 ±
Sensitivity 0.884 > 0.570
Positive Predictive Value 0.904 < 0.932
Total TP 405 > 261
Total TN 1085153 < 1085321
Total FP 80 > 35
Total FP CONTRA 10 > 6
Total FP INCONS 33 > 13
Total FP COMP 37 > 16
Total FN 53 < 197
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Carnac(seed)).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 405
Total TN 1085153
Total FP 80
Total FP CONTRA 10
Total FP INCONS 33
Total FP COMP 37
Total FN 53
Total Scores
MCC 0.894
Average MCC ± 95% Confidence Intervals 0.894 ±
Sensitivity 0.884
Positive Predictive Value 0.904
Nr of predictions 1

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.89 0.88 0.90 405 1085153 80 10 33 37 53

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 261
Total TN 1085321
Total FP 35
Total FP CONTRA 6
Total FP INCONS 13
Total FP COMP 16
Total FN 197
Total Scores
MCC 0.729
Average MCC ± 95% Confidence Intervals 0.729 ±
Sensitivity 0.570
Positive Predictive Value 0.932
Nr of predictions 1

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.73 0.57 0.93 261 1085321 35 6 13 16 197

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.