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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PknotsRG - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PknotsRG & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric PknotsRG Carnac(seed)
MCC 0.774 > 0.729
Average MCC ± 95% Confidence Intervals 0.774 ± > 0.729 ±
Sensitivity 0.760 > 0.570
Positive Predictive Value 0.789 < 0.932
Total TP 348 > 261
Total TN 1085160 < 1085321
Total FP 130 > 35
Total FP CONTRA 18 > 6
Total FP INCONS 75 > 13
Total FP COMP 37 > 16
Total FN 110 < 197
P-value 0.0

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Performance plots


  1. Comparison of performance of PknotsRG and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PknotsRG and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PknotsRG and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PknotsRG and Carnac(seed)).

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Performance of PknotsRG - scored higher in this pairwise comparison

1. Total counts & total scores for PknotsRG

Total Base Pair Counts
Total TP 348
Total TN 1085160
Total FP 130
Total FP CONTRA 18
Total FP INCONS 75
Total FP COMP 37
Total FN 110
Total Scores
MCC 0.774
Average MCC ± 95% Confidence Intervals 0.774 ±
Sensitivity 0.760
Positive Predictive Value 0.789
Nr of predictions 1

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2. Individual counts for PknotsRG [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.77 0.76 0.79 348 1085160 130 18 75 37 110

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 261
Total TN 1085321
Total FP 35
Total FP CONTRA 6
Total FP INCONS 13
Total FP COMP 16
Total FN 197
Total Scores
MCC 0.729
Average MCC ± 95% Confidence Intervals 0.729 ±
Sensitivity 0.570
Positive Predictive Value 0.932
Nr of predictions 1

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.73 0.57 0.93 261 1085321 35 6 13 16 197

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.