CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(seed) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(seed) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric RNAalifold(seed) Carnac(seed)
MCC 0.872 > 0.729
Average MCC ± 95% Confidence Intervals 0.872 ± > 0.729 ±
Sensitivity 0.841 > 0.570
Positive Predictive Value 0.904 < 0.932
Total TP 385 > 261
Total TN 1085175 < 1085321
Total FP 58 > 35
Total FP CONTRA 7 > 6
Total FP INCONS 34 > 13
Total FP COMP 17 > 16
Total FN 73 < 197
P-value 0.0

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Performance plots


  1. Comparison of performance of RNAalifold(seed) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(seed) and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(seed) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(seed) and Carnac(seed)).

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Performance of RNAalifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(seed)

Total Base Pair Counts
Total TP 385
Total TN 1085175
Total FP 58
Total FP CONTRA 7
Total FP INCONS 34
Total FP COMP 17
Total FN 73
Total Scores
MCC 0.872
Average MCC ± 95% Confidence Intervals 0.872 ±
Sensitivity 0.841
Positive Predictive Value 0.904
Nr of predictions 1

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2. Individual counts for RNAalifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.87 0.84 0.90 385 1085175 58 7 34 17 73

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 261
Total TN 1085321
Total FP 35
Total FP CONTRA 6
Total FP INCONS 13
Total FP COMP 16
Total FN 197
Total Scores
MCC 0.729
Average MCC ± 95% Confidence Intervals 0.729 ±
Sensitivity 0.570
Positive Predictive Value 0.932
Nr of predictions 1

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.73 0.57 0.93 261 1085321 35 6 13 16 197

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.