CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RSpredict(seed) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RSpredict(seed) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric RSpredict(seed) Carnac(seed)
MCC 0.778 > 0.729
Average MCC ± 95% Confidence Intervals 0.778 ± > 0.729 ±
Sensitivity 0.755 > 0.570
Positive Predictive Value 0.801 < 0.932
Total TP 346 > 261
Total TN 1085169 < 1085321
Total FP 116 > 35
Total FP CONTRA 15 > 6
Total FP INCONS 71 > 13
Total FP COMP 30 > 16
Total FN 112 < 197
P-value 0.0

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Performance plots


  1. Comparison of performance of RSpredict(seed) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RSpredict(seed) and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RSpredict(seed) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RSpredict(seed) and Carnac(seed)).

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Performance of RSpredict(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RSpredict(seed)

Total Base Pair Counts
Total TP 346
Total TN 1085169
Total FP 116
Total FP CONTRA 15
Total FP INCONS 71
Total FP COMP 30
Total FN 112
Total Scores
MCC 0.778
Average MCC ± 95% Confidence Intervals 0.778 ±
Sensitivity 0.755
Positive Predictive Value 0.801
Nr of predictions 1

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2. Individual counts for RSpredict(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.78 0.76 0.80 346 1085169 116 15 71 30 112

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 261
Total TN 1085321
Total FP 35
Total FP CONTRA 6
Total FP INCONS 13
Total FP COMP 16
Total FN 197
Total Scores
MCC 0.729
Average MCC ± 95% Confidence Intervals 0.729 ±
Sensitivity 0.570
Positive Predictive Value 0.932
Nr of predictions 1

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.73 0.57 0.93 261 1085321 35 6 13 16 197

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.