CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Sfold - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Sfold & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric Sfold Mastr(seed)
MCC 0.391 > 0.000
Average MCC ± 95% Confidence Intervals 0.392 ± 0.401 > 0.000 ± 0.000
Sensitivity 0.332 > 0.000
Positive Predictive Value 0.462 > 0.000
Total TP 486 > 0
Total TN 4973725 < 4974778
Total FP 741 > 0
Total FP CONTRA 106 > 0
Total FP INCONS 461 > 0
Total FP COMP 174 > 0
Total FN 980 < 1466
P-value 0.0

^top




Performance plots


  1. Comparison of performance of Sfold and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Sfold and Mastr(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Sfold and Mastr(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Sfold and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Sfold and Mastr(seed)).

^top





Performance of Sfold - scored higher in this pairwise comparison

1. Total counts & total scores for Sfold

Total Base Pair Counts
Total TP 486
Total TN 4973725
Total FP 741
Total FP CONTRA 106
Total FP INCONS 461
Total FP COMP 174
Total FN 980
Total Scores
MCC 0.391
Average MCC ± 95% Confidence Intervals 0.392 ± 0.401
Sensitivity 0.332
Positive Predictive Value 0.462
Nr of predictions 3

^top



2. Individual counts for Sfold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00306 0.21 0.19 0.24 88 1445476 332 57 229 46 374
CRW_00379 0.44 0.34 0.58 183 2126636 205 17 117 71 351
CRW_00800 0.52 0.46 0.59 215 1401613 204 32 115 57 255

^top



Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 4974778
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 1466
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 3

^top



2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00306 0.00 0.00 0.00 0 1445850 0 0 0 0 462
CRW_00379 0.00 0.00 0.00 0 2126953 0 0 0 0 534
CRW_00800 0.00 0.00 0.00 0 1401975 0 0 0 0 470

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.