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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(20) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(20) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(20) CRWrnafold
MCC 0.762 > 0.484
Average MCC ± 95% Confidence Intervals 0.733 ± 0.012 > 0.465 ± 0.021
Sensitivity 0.636 > 0.476
Positive Predictive Value 0.914 > 0.494
Total TP 20953 > 15671
Total TN 40119103 > 40110311
Total FP 2645 < 17443
Total FP CONTRA 459 < 2052
Total FP INCONS 1501 < 13982
Total FP COMP 685 < 1409
Total FN 11995 < 17277
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of CentroidAlifold(20) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(20) and CRWrnafold).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for CentroidAlifold(20) and CRWrnafold).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(20) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(20) and CRWrnafold).

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Performance of CentroidAlifold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(20)

Total Base Pair Counts
Total TP 20953
Total TN 40119103
Total FP 2645
Total FP CONTRA 459
Total FP INCONS 1501
Total FP COMP 685
Total FN 11995
Total Scores
MCC 0.762
Average MCC ± 95% Confidence Intervals 0.733 ± 0.012
Sensitivity 0.636
Positive Predictive Value 0.914
Nr of predictions 234

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2. Individual counts for CentroidAlifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.56 0.41 0.75 40 47842 13 0 13 0 57
ASE_00005 0.74 0.56 0.97 66 57902 2 0 2 0 51
ASE_00006 0.66 0.49 0.88 46 47534 6 0 6 0 47
ASE_00007 0.84 0.73 0.96 80 59602 3 0 3 0 30
ASE_00012 0.71 0.56 0.90 69 73843 11 2 6 3 54
ASE_00018 0.76 0.60 0.95 81 80516 4 1 3 0 53
ASE_00020 0.60 0.41 0.87 52 73860 8 5 3 0 74
ASE_00021 0.55 0.36 0.86 57 104130 12 2 7 3 103
ASE_00022 0.79 0.63 1.00 78 82950 4 0 0 4 46
ASE_00028 0.74 0.55 1.00 69 84597 3 0 0 3 57
ASE_00035 0.71 0.55 0.93 65 70430 8 0 5 3 53
ASE_00037 0.80 0.65 1.00 71 59269 1 0 0 1 39
ASE_00038 0.76 0.58 1.00 59 53569 0 0 0 0 42
ASE_00040 0.80 0.66 0.97 88 78912 5 0 3 2 45
ASE_00041 0.77 0.66 0.90 71 57551 8 0 8 0 37
ASE_00042 0.60 0.44 0.81 64 90021 15 0 15 0 81
ASE_00044 0.83 0.70 0.99 74 54540 1 0 1 0 31
ASE_00064 0.79 0.65 0.97 58 45391 2 0 2 0 31
ASE_00068 0.59 0.41 0.85 35 37634 6 0 6 0 50
ASE_00074 0.79 0.63 1.00 75 67821 1 0 0 1 44
ASE_00075 0.56 0.35 0.89 57 108747 12 1 6 5 105
ASE_00077 0.78 0.65 0.93 56 45090 4 1 3 0 30
ASE_00078 0.84 0.71 1.00 59 43012 0 0 0 0 24
ASE_00080 0.46 0.32 0.67 39 71573 19 1 18 0 84
ASE_00081 0.77 0.60 0.98 58 49711 1 0 1 0 39
ASE_00082 0.69 0.49 0.98 57 70442 7 0 1 6 59
ASE_00083 0.73 0.55 0.98 60 62420 1 0 1 0 50
ASE_00084 0.77 0.61 0.97 60 53566 2 1 1 0 39
ASE_00087 0.61 0.39 0.97 56 88352 2 0 2 0 88
ASE_00090 0.76 0.58 1.00 59 55552 0 0 0 0 42
ASE_00092 0.71 0.52 0.97 59 63485 2 1 1 0 54
ASE_00099 0.83 0.68 1.00 82 64538 0 0 0 0 38
ASE_00104 0.79 0.64 0.97 76 64183 2 0 2 0 43
ASE_00105 0.53 0.37 0.76 41 64207 13 2 11 0 70
ASE_00107 0.78 0.65 0.95 82 73067 4 0 4 0 45
ASE_00115 0.77 0.60 0.98 61 54553 1 0 1 0 40
ASE_00118 0.68 0.49 0.94 50 60673 4 1 2 1 52
ASE_00119 0.64 0.43 0.96 46 62787 2 1 1 0 62
ASE_00123 0.75 0.60 0.94 51 38449 3 1 2 0 34
ASE_00125 0.71 0.50 1.00 44 39296 0 0 0 0 44
ASE_00126 0.80 0.65 1.00 53 40417 1 0 0 1 29
ASE_00128 0.76 0.58 1.00 58 53243 0 0 0 0 42
ASE_00129 0.75 0.57 1.00 63 62772 0 0 0 0 48
ASE_00131 0.73 0.53 1.00 45 39295 0 0 0 0 40
ASE_00134 0.74 0.61 0.89 58 50338 7 0 7 0 37
ASE_00135 0.58 0.43 0.78 47 63130 13 0 13 0 62
ASE_00136 0.77 0.62 0.95 57 48145 3 0 3 0 35
ASE_00137 0.68 0.51 0.91 50 48461 6 0 5 1 48
ASE_00138 0.82 0.69 0.98 56 40413 1 1 0 0 25
ASE_00140 0.60 0.40 0.91 50 70821 5 3 2 0 75
ASE_00142 0.82 0.69 0.97 84 67074 5 0 3 2 38
ASE_00146 0.81 0.68 0.97 84 70789 3 0 3 0 40
ASE_00153 0.34 0.26 0.45 19 57588 23 4 19 0 54
ASE_00163 0.78 0.63 0.97 59 53240 2 1 1 0 34
ASE_00165 0.73 0.54 0.98 55 52919 2 0 1 1 46
ASE_00170 0.75 0.62 0.91 58 48764 6 1 5 0 35
ASE_00171 0.79 0.63 0.98 59 48456 2 0 1 1 35
ASE_00172 0.69 0.51 0.95 54 58939 3 2 1 0 52
ASE_00174 0.60 0.44 0.83 48 61017 10 1 9 0 61
ASE_00175 0.66 0.51 0.86 55 59967 9 1 8 0 52
ASE_00179 0.74 0.60 0.93 50 44199 5 2 2 1 34
ASE_00180 0.74 0.57 0.97 57 51301 2 1 1 0 43
ASE_00181 0.71 0.54 0.93 57 57569 6 1 3 2 49
ASE_00182 0.62 0.41 0.93 56 84195 4 1 3 0 80
ASE_00183 0.70 0.51 0.97 58 61365 2 1 1 0 55
ASE_00184 0.76 0.59 0.98 60 54554 1 0 1 0 42
ASE_00185 0.63 0.41 0.96 53 73481 2 1 1 0 75
ASE_00186 0.71 0.55 0.91 73 78923 10 0 7 3 59
ASE_00190 0.75 0.56 1.00 50 45401 2 0 0 2 40
ASE_00197 0.66 0.50 0.87 72 89170 12 0 11 1 73
ASE_00198 0.76 0.60 0.97 61 52587 2 0 2 0 41
ASE_00203 0.76 0.58 0.98 56 46608 1 0 1 0 40
ASE_00212 0.63 0.45 0.88 67 93885 10 0 9 1 81
ASE_00214 0.72 0.54 0.97 56 56222 3 1 1 1 47
ASE_00215 0.56 0.37 0.84 37 48472 7 0 7 0 62
ASE_00216 0.82 0.67 1.00 55 39285 0 0 0 0 27
ASE_00217 0.82 0.69 0.98 62 40407 2 0 1 1 28
ASE_00221 0.84 0.73 0.97 85 64532 3 0 3 0 32
ASE_00228 0.74 0.62 0.88 53 46911 8 3 4 1 33
ASE_00229 0.77 0.60 0.98 52 42433 3 0 1 2 35
ASE_00231 0.64 0.48 0.87 46 47842 7 0 7 0 50
ASE_00232 0.81 0.68 0.97 57 38444 2 2 0 0 27
ASE_00234 0.58 0.42 0.82 54 75400 12 5 7 0 75
ASE_00238 0.55 0.40 0.75 46 64200 15 3 12 0 68
ASE_00241 0.84 0.72 0.97 63 43891 2 0 2 0 24
ASE_00242 0.87 0.77 0.99 86 60988 3 0 1 2 26
ASE_00248 0.84 0.72 0.99 82 62398 2 0 1 1 32
ASE_00254 0.83 0.70 0.98 57 36798 1 0 1 0 25
ASE_00255 0.57 0.41 0.79 53 74624 14 0 14 0 77
ASE_00257 0.66 0.51 0.86 49 50983 8 2 6 0 48
ASE_00263 0.72 0.53 0.98 63 70436 1 1 0 0 57
ASE_00267 0.82 0.67 1.00 59 45091 1 0 0 1 29
ASE_00270 0.56 0.35 0.90 45 72340 6 0 5 1 83
ASE_00274 0.65 0.47 0.91 48 55558 5 3 2 0 55
ASE_00277 0.62 0.47 0.83 43 48153 9 2 7 0 48
ASE_00279 0.78 0.63 0.96 64 53234 3 0 3 0 37
ASE_00280 0.76 0.59 0.97 58 51943 2 1 1 0 40
ASE_00281 0.80 0.67 0.97 59 44490 2 0 2 0 29
ASE_00282 0.71 0.50 1.00 64 77751 0 0 0 0 63
ASE_00283 0.72 0.54 0.97 58 61716 2 0 2 0 49
ASE_00284 0.74 0.56 0.98 60 58250 1 0 1 0 48
ASE_00285 0.73 0.56 0.94 68 68934 4 2 2 0 54
ASE_00286 0.79 0.64 0.98 59 46605 1 0 1 0 33
ASE_00287 0.67 0.53 0.83 55 54880 11 0 11 0 48
ASE_00292 0.80 0.65 0.98 90 81718 3 0 2 1 48
ASE_00294 0.71 0.52 0.96 89 114388 5 0 4 1 82
ASE_00296 0.72 0.57 0.92 82 91717 8 1 6 1 63
ASE_00297 0.59 0.43 0.82 42 52924 9 2 7 0 56
ASE_00298 0.72 0.54 0.97 61 67465 2 1 1 0 52
ASE_00318 0.79 0.63 0.99 74 80125 8 0 1 7 44
ASE_00328 0.78 0.62 0.99 69 72701 6 0 1 5 43
ASE_00332 0.71 0.54 0.94 74 81731 5 0 5 0 64
ASE_00335 0.74 0.59 0.92 69 75391 13 0 6 7 47
ASE_00340 0.75 0.61 0.93 52 46000 8 0 4 4 33
ASE_00342 0.86 0.75 0.99 86 62394 1 0 1 0 29
ASE_00353 0.70 0.50 0.98 54 57915 2 1 0 1 53
ASE_00361 0.65 0.42 1.00 53 75413 0 0 0 0 74
ASE_00362 0.76 0.58 0.98 53 48151 2 0 1 1 38
ASE_00363 0.71 0.56 0.88 53 51300 7 0 7 0 41
ASE_00364 0.69 0.53 0.89 56 54222 7 1 6 0 49
ASE_00366 0.72 0.58 0.89 57 58589 7 1 6 0 41
ASE_00367 0.84 0.71 1.00 61 43010 1 0 0 1 25
ASE_00369 0.77 0.60 0.98 64 55880 1 0 1 0 43
ASE_00370 0.76 0.60 0.96 50 41853 2 0 2 0 34
ASE_00372 0.75 0.57 0.98 57 51945 1 0 1 0 43
ASE_00374 0.81 0.66 1.00 58 44792 0 0 0 0 30
ASE_00376 0.72 0.55 0.94 58 56891 4 0 4 0 47
ASE_00377 0.66 0.50 0.88 53 57570 7 1 6 0 54
ASE_00379 0.76 0.61 0.96 54 46000 3 1 1 1 35
ASE_00382 0.85 0.73 0.98 61 41843 2 0 1 1 23
ASE_00383 0.77 0.59 1.00 62 54553 0 0 0 0 43
ASE_00384 0.77 0.62 0.97 57 48457 2 1 1 0 35
ASE_00386 0.74 0.56 0.98 54 50348 1 0 1 0 42
ASE_00387 0.66 0.49 0.88 51 55887 7 0 7 0 53
ASE_00388 0.78 0.62 0.98 55 45697 2 0 1 1 34
ASE_00390 0.77 0.65 0.92 55 42135 5 2 3 0 30
ASE_00393 0.72 0.58 0.90 54 47835 6 0 6 0 39
ASE_00394 0.79 0.63 0.98 59 46911 1 0 1 0 34
ASE_00395 0.76 0.63 0.91 53 41558 5 0 5 0 31
ASE_00396 0.82 0.69 0.98 57 41558 1 0 1 0 26
ASE_00397 0.74 0.54 1.00 57 54558 0 0 0 0 48
ASE_00398 0.71 0.52 0.96 54 55889 2 0 2 0 50
ASE_00400 0.77 0.60 0.98 64 57905 2 0 1 1 42
ASE_00401 0.65 0.44 0.95 56 76969 3 1 2 0 70
ASE_00402 0.79 0.62 1.00 53 42433 0 0 0 0 32
ASE_00403 0.75 0.57 0.98 61 55883 1 0 1 0 46
ASE_00404 0.80 0.66 0.98 56 43014 2 0 1 1 29
ASE_00406 0.77 0.61 0.98 57 48770 1 0 1 0 37
ASE_00411 0.65 0.54 0.77 48 49393 14 6 8 0 41
ASE_00412 0.54 0.40 0.72 42 58253 16 2 14 0 63
ASE_00413 0.77 0.64 0.93 52 44495 5 3 1 1 29
ASE_00415 0.55 0.39 0.78 40 54895 11 0 11 0 63
ASE_00416 0.73 0.58 0.93 74 77341 6 1 5 0 53
ASE_00419 0.69 0.54 0.88 56 54882 8 3 5 0 47
ASE_00422 0.69 0.56 0.84 53 46908 11 0 10 1 41
ASE_00423 0.76 0.66 0.88 72 56871 11 0 10 1 37
ASE_00428 0.76 0.64 0.90 80 76547 9 1 8 0 45
ASE_00430 0.74 0.57 0.96 55 46914 2 0 2 0 42
ASE_00437 0.56 0.46 0.68 62 79310 29 0 29 0 73
ASE_00441 0.62 0.41 0.94 46 64212 4 0 3 1 66
ASE_00448 0.81 0.71 0.94 79 64177 5 0 5 0 33
ASE_00451 0.79 0.66 0.95 82 70790 4 0 4 0 43
CRW_00054 0.86 0.80 0.93 364 1107423 43 10 19 14 92
CRW_00068 0.85 0.80 0.91 365 1108906 48 11 23 14 92
CRW_00140 0.86 0.80 0.92 372 1135875 46 11 20 15 91
CRW_00173 0.80 0.75 0.86 332 1082272 67 11 41 15 113
CRW_00245 0.87 0.81 0.93 367 1105932 46 9 20 17 86
CRW_00270 0.86 0.80 0.92 362 1111893 46 11 20 15 93
CRW_00271 0.84 0.77 0.91 355 1122363 48 8 25 15 107
CRW_00273 0.86 0.79 0.92 354 1085218 46 8 21 17 92
CRW_00275 0.87 0.81 0.93 371 1114870 46 9 21 16 86
CRW_00277 0.85 0.78 0.91 354 1110408 50 12 21 17 99
CRW_00278 0.84 0.78 0.91 351 1129869 54 7 29 18 99
CRW_00280 0.84 0.79 0.89 357 1117860 63 9 34 20 96
CRW_00281 0.84 0.77 0.92 357 1144951 49 9 24 16 107
CRW_00284 0.84 0.77 0.91 350 1131377 50 7 26 17 106
CRW_00285 0.83 0.77 0.90 353 1117869 56 11 27 18 105
CRW_00466 0.86 0.79 0.93 364 1116372 45 9 20 16 94
CRW_00589 0.86 0.78 0.94 347 1094091 45 2 20 23 98
CRW_00590 0.86 0.79 0.93 359 1119369 53 3 25 25 93
CRW_00591 0.86 0.79 0.92 354 1098520 55 6 23 26 92
CRW_00772 0.79 0.73 0.85 295 945652 81 5 48 28 109
CRW_00789 0.83 0.76 0.91 340 1137411 63 5 30 28 107
CRW_00849 0.82 0.76 0.88 357 1117854 65 10 39 16 113
CRW_00997 0.85 0.80 0.91 369 1135873 50 13 23 14 95
PDB_00571 0.87 0.80 0.95 20 3300 1 1 0 0 5
PDB_00703 0.81 0.70 0.92 348 1073468 55 8 21 26 147
PDB_00828 0.88 0.78 1.00 21 2464 0 0 0 0 6
PDB_00829 0.86 0.75 1.00 18 2260 0 0 0 0 6
PDB_01020 0.86 0.74 1.00 17 2261 1 0 0 1 6
PDB_01073 0.84 0.71 1.00 24 4347 1 0 0 1 10
PDB_01273 0.80 0.69 0.91 341 1117886 62 6 27 29 150
RFA_00599 0.89 0.83 0.96 92 101379 9 1 3 5 19
RFA_00601 0.90 0.86 0.93 98 99130 13 1 6 6 16
RFA_00602 0.87 0.84 0.91 97 101368 18 1 9 8 19
TMR_00017 0.80 0.65 0.99 66 67094 1 0 1 0 36
TMR_00018 0.65 0.54 0.78 50 64556 15 5 9 1 42
TMR_00038 0.68 0.56 0.82 62 71177 15 5 9 1 48
TMR_00042 0.66 0.53 0.83 52 62772 12 4 7 1 46
TMR_00046 0.53 0.45 0.63 43 62767 26 4 21 1 53
TMR_00048 0.66 0.53 0.82 50 64919 12 7 4 1 45
TMR_00080 0.63 0.52 0.77 50 70435 15 8 7 0 46
TMR_00082 0.66 0.56 0.78 54 67827 18 7 8 3 42
TMR_00123 0.79 0.64 0.97 65 66363 3 1 1 1 36
TMR_00137 0.68 0.55 0.83 49 61016 13 6 4 3 40
TMR_00142 0.65 0.46 0.92 47 70825 11 0 4 7 55
TMR_00207 0.74 0.57 0.97 59 72329 4 1 1 2 44
TMR_00257 0.78 0.64 0.94 63 67094 4 4 0 0 35
TMR_00271 0.55 0.44 0.68 40 64202 24 6 13 5 51
TMR_00332 0.67 0.48 0.92 48 67109 5 1 3 1 51
TMR_00366 0.70 0.49 1.00 49 67847 7 0 0 7 51
TMR_00378 0.63 0.46 0.87 45 67844 15 1 6 8 52
TMR_00399 0.60 0.49 0.74 46 64918 16 6 10 0 48
TMR_00404 0.60 0.50 0.72 46 67464 21 3 15 3 46
TMR_00427 0.63 0.45 0.86 44 67477 8 7 0 1 53
TMR_00443 0.73 0.58 0.92 60 67096 6 0 5 1 44
TMR_00451 0.63 0.55 0.73 49 63479 20 10 8 2 40
TMR_00458 0.65 0.54 0.79 50 63483 15 6 7 2 43
TMR_00469 0.79 0.69 0.91 69 64544 10 6 1 3 31
TMR_00472 0.72 0.64 0.82 62 64544 15 7 7 1 35
TMR_00519 0.63 0.53 0.75 50 63123 19 5 12 2 45
TMR_00520 0.63 0.48 0.81 48 63131 13 3 8 2 51
TMR_00522 0.62 0.47 0.82 46 63134 15 4 6 5 51
TMR_00528 0.67 0.54 0.84 52 63128 15 4 6 5 45
TMR_00540 0.60 0.45 0.81 47 73478 11 4 7 0 57
TMR_00568 0.77 0.68 0.87 67 60649 15 1 9 5 32
TMR_00571 0.80 0.71 0.91 70 60649 12 1 6 5 29
TMR_00580 0.78 0.68 0.89 68 60650 13 2 6 5 32
TMR_00584 0.80 0.70 0.91 68 61000 10 3 4 3 29
TMR_00586 0.74 0.66 0.83 64 60998 18 6 7 5 33
TMR_00616 0.74 0.65 0.85 64 67086 12 7 4 1 35
TMR_00699 0.66 0.49 0.89 50 67105 6 1 5 0 52
TMR_00702 0.60 0.45 0.79 45 67104 12 2 10 0 55
TMR_00703 0.71 0.57 0.90 56 67466 6 2 4 0 43

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 15671
Total TN 40110311
Total FP 17443
Total FP CONTRA 2052
Total FP INCONS 13982
Total FP COMP 1409
Total FN 17277
Total Scores
MCC 0.484
Average MCC ± 95% Confidence Intervals 0.465 ± 0.021
Sensitivity 0.476
Positive Predictive Value 0.494
Nr of predictions 234

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.69 0.68 0.69 66 47800 30 9 20 1 31
ASE_00005 0.50 0.48 0.52 56 57863 51 3 48 0 61
ASE_00006 0.29 0.29 0.30 27 47495 65 8 56 1 66
ASE_00007 0.34 0.33 0.36 36 59585 65 3 61 1 74
ASE_00012 0.42 0.41 0.43 51 73800 75 6 63 6 72
ASE_00018 0.53 0.51 0.56 68 80480 54 4 49 1 66
ASE_00020 0.63 0.60 0.68 75 73809 39 6 30 3 51
ASE_00021 0.59 0.55 0.62 88 104055 57 8 45 4 72
ASE_00022 0.49 0.46 0.51 57 82917 58 9 45 4 67
ASE_00028 0.57 0.55 0.59 69 84550 54 9 38 7 57
ASE_00035 0.12 0.12 0.13 14 70389 100 12 85 3 104
ASE_00037 0.41 0.39 0.43 43 59240 59 5 52 2 67
ASE_00038 0.55 0.53 0.57 54 53533 46 4 37 5 47
ASE_00040 0.45 0.43 0.48 57 78883 69 4 59 6 76
ASE_00041 0.39 0.36 0.41 39 57536 61 5 50 6 69
ASE_00042 0.42 0.40 0.45 58 89970 75 6 66 3 87
ASE_00044 0.78 0.76 0.79 80 54514 26 4 17 5 25
ASE_00064 0.35 0.35 0.35 31 45363 66 2 55 9 58
ASE_00068 0.21 0.20 0.22 17 37599 61 6 53 2 68
ASE_00074 0.50 0.49 0.51 58 67783 56 4 51 1 61
ASE_00075 0.64 0.60 0.68 97 108669 49 5 40 4 65
ASE_00077 0.32 0.30 0.33 26 45072 58 8 44 6 60
ASE_00078 0.12 0.12 0.12 10 42988 78 4 69 5 73
ASE_00080 0.35 0.33 0.36 41 71518 72 5 67 0 82
ASE_00081 0.32 0.30 0.35 29 49686 56 3 52 1 68
ASE_00082 0.45 0.41 0.49 48 70402 60 1 49 10 68
ASE_00083 0.75 0.71 0.79 78 62382 28 1 20 7 32
ASE_00084 0.39 0.38 0.40 38 53532 60 6 52 2 61
ASE_00087 0.58 0.54 0.62 78 88285 48 3 44 1 66
ASE_00090 0.61 0.61 0.61 62 55510 44 2 37 5 39
ASE_00092 0.56 0.55 0.56 62 63436 53 9 39 5 51
ASE_00099 0.64 0.63 0.65 75 64505 41 4 36 1 45
ASE_00104 0.46 0.44 0.48 52 64153 57 3 53 1 67
ASE_00105 0.47 0.46 0.49 51 64157 59 7 46 6 60
ASE_00107 0.66 0.64 0.69 81 73036 37 2 34 1 46
ASE_00115 0.66 0.63 0.69 64 54522 37 4 25 8 37
ASE_00118 0.49 0.47 0.51 48 60631 53 2 45 6 54
ASE_00119 0.86 0.84 0.88 91 62732 15 2 10 3 17
ASE_00123 0.35 0.33 0.37 28 38427 54 0 48 6 57
ASE_00125 0.51 0.50 0.52 44 39255 42 4 37 1 44
ASE_00126 0.38 0.37 0.39 30 40393 49 6 41 2 52
ASE_00128 0.62 0.60 0.65 60 53208 37 6 27 4 40
ASE_00129 0.64 0.60 0.67 67 62735 34 3 30 1 44
ASE_00131 0.51 0.48 0.55 41 39265 39 1 33 5 44
ASE_00134 0.42 0.42 0.43 40 50310 59 5 48 6 55
ASE_00135 0.46 0.46 0.46 50 63082 60 7 51 2 59
ASE_00136 0.45 0.45 0.45 41 48114 54 8 42 4 51
ASE_00137 0.37 0.37 0.37 36 48419 62 3 58 1 62
ASE_00138 0.24 0.23 0.25 19 40395 61 5 51 5 62
ASE_00140 0.64 0.59 0.69 74 70769 34 7 26 1 51
ASE_00142 0.70 0.66 0.73 81 67050 35 3 27 5 41
ASE_00146 0.49 0.47 0.52 58 70765 54 8 45 1 66
ASE_00153 0.68 0.68 0.67 50 57555 66 2 23 41 23
ASE_00163 0.29 0.29 0.30 27 53210 73 5 59 9 66
ASE_00165 0.44 0.43 0.46 43 52882 50 6 44 0 58
ASE_00170 0.66 0.65 0.67 60 48739 34 6 23 5 33
ASE_00171 0.46 0.45 0.48 42 48429 45 5 40 0 52
ASE_00172 0.56 0.54 0.58 57 58897 43 3 39 1 49
ASE_00174 0.47 0.45 0.49 49 60976 53 4 46 3 60
ASE_00175 0.24 0.24 0.25 26 59926 86 2 77 7 81
ASE_00179 0.56 0.56 0.56 47 44169 39 7 30 2 37
ASE_00180 0.55 0.53 0.58 53 51268 40 8 31 1 47
ASE_00181 0.42 0.42 0.43 44 57527 64 2 57 5 62
ASE_00182 0.51 0.49 0.54 67 84130 58 4 54 0 69
ASE_00183 0.55 0.53 0.57 60 61319 49 5 41 3 53
ASE_00184 0.51 0.50 0.52 51 54516 49 4 44 1 51
ASE_00185 0.64 0.62 0.66 79 73417 44 5 35 4 49
ASE_00186 0.62 0.60 0.65 79 78882 47 4 38 5 53
ASE_00190 0.52 0.51 0.53 46 45365 46 7 33 6 44
ASE_00197 0.57 0.54 0.60 79 89122 56 5 47 4 66
ASE_00198 0.56 0.56 0.57 57 52550 43 7 36 0 45
ASE_00203 0.62 0.61 0.63 59 46572 39 5 29 5 37
ASE_00212 0.58 0.55 0.61 82 93826 57 4 49 4 66
ASE_00214 0.72 0.71 0.74 73 56181 37 4 22 11 30
ASE_00215 0.46 0.44 0.47 44 48422 51 4 46 1 55
ASE_00216 0.71 0.71 0.72 58 39259 23 7 16 0 24
ASE_00217 0.26 0.24 0.28 22 40391 58 3 54 1 68
ASE_00221 0.49 0.44 0.55 51 64527 45 1 41 3 66
ASE_00228 0.34 0.34 0.35 29 46887 61 9 46 6 57
ASE_00229 0.44 0.43 0.46 37 42405 47 5 39 3 50
ASE_00231 0.62 0.63 0.63 60 47799 37 7 29 1 36
ASE_00232 0.68 0.68 0.69 57 38420 27 8 18 1 27
ASE_00234 0.52 0.50 0.55 64 75350 55 4 48 3 65
ASE_00238 0.56 0.54 0.57 62 64152 51 3 44 4 52
ASE_00241 0.53 0.52 0.54 45 43873 46 2 36 8 42
ASE_00242 0.48 0.46 0.50 51 60973 54 3 48 3 61
ASE_00248 0.28 0.27 0.30 31 62378 72 7 65 0 83
ASE_00254 0.62 0.61 0.64 50 36778 34 3 25 6 32
ASE_00255 0.58 0.55 0.61 72 74573 52 4 42 6 58
ASE_00257 0.53 0.53 0.53 51 50944 49 6 39 4 46
ASE_00263 0.77 0.77 0.77 92 70380 29 6 22 1 28
ASE_00267 0.17 0.17 0.17 15 45064 77 8 63 6 73
ASE_00270 0.62 0.59 0.65 76 72273 41 7 34 0 52
ASE_00274 0.41 0.41 0.42 42 55512 57 10 47 0 61
ASE_00277 0.30 0.30 0.31 27 48117 61 8 53 0 64
ASE_00279 0.30 0.29 0.31 29 53208 64 10 54 0 72
ASE_00280 0.42 0.42 0.43 41 51907 56 5 50 1 57
ASE_00281 0.47 0.44 0.49 39 44472 41 1 39 1 49
ASE_00282 0.55 0.53 0.58 67 77699 54 7 42 5 60
ASE_00283 0.73 0.72 0.75 77 61673 30 3 23 4 30
ASE_00284 0.52 0.51 0.52 55 58206 52 7 43 2 53
ASE_00285 0.50 0.48 0.53 58 68897 54 7 44 3 64
ASE_00286 0.28 0.28 0.29 26 46574 70 8 57 5 66
ASE_00287 0.34 0.32 0.36 33 54854 63 5 54 4 70
ASE_00292 0.45 0.43 0.48 59 81687 65 5 59 1 79
ASE_00294 0.38 0.36 0.41 61 114334 89 2 84 3 110
ASE_00296 0.21 0.21 0.22 30 91671 105 6 99 0 115
ASE_00297 0.54 0.54 0.54 53 52877 48 5 40 3 45
ASE_00298 0.41 0.39 0.43 44 67425 66 1 58 7 69
ASE_00318 0.53 0.53 0.54 62 80086 56 11 41 4 56
ASE_00328 0.56 0.54 0.58 60 72668 47 7 36 4 52
ASE_00332 0.55 0.54 0.57 74 81680 58 5 51 2 64
ASE_00335 0.53 0.52 0.55 60 75356 56 10 40 6 56
ASE_00340 0.32 0.32 0.32 27 45971 62 10 48 4 58
ASE_00342 0.55 0.52 0.58 60 62378 47 2 41 4 55
ASE_00353 0.38 0.38 0.38 41 57863 70 3 63 4 66
ASE_00361 0.47 0.45 0.50 57 75352 61 9 48 4 70
ASE_00362 0.63 0.62 0.64 56 48117 36 4 28 4 35
ASE_00363 0.34 0.34 0.34 32 51267 68 4 57 7 62
ASE_00364 0.44 0.42 0.46 44 54189 58 4 48 6 61
ASE_00366 0.42 0.42 0.41 41 58554 62 13 45 4 57
ASE_00367 0.26 0.27 0.26 23 42982 69 8 58 3 63
ASE_00369 0.65 0.64 0.67 68 55844 38 4 29 5 39
ASE_00370 0.51 0.50 0.51 42 41823 47 4 36 7 42
ASE_00372 0.59 0.59 0.58 59 51902 44 8 34 2 41
ASE_00374 0.19 0.18 0.20 16 44769 65 13 52 0 72
ASE_00376 0.43 0.43 0.44 45 56851 57 3 54 0 60
ASE_00377 0.68 0.66 0.70 71 57529 36 4 26 6 36
ASE_00379 0.44 0.43 0.45 38 45971 53 6 41 6 51
ASE_00382 0.42 0.42 0.42 35 41822 52 7 41 4 49
ASE_00383 0.32 0.31 0.34 33 54517 65 4 61 0 72
ASE_00384 0.31 0.30 0.31 28 48427 61 3 58 0 64
ASE_00386 0.39 0.39 0.41 37 50312 58 7 47 4 59
ASE_00387 0.46 0.45 0.47 47 55844 57 5 49 3 57
ASE_00388 0.33 0.33 0.33 29 45665 65 5 54 6 60
ASE_00390 0.20 0.19 0.21 16 42119 67 2 58 7 69
ASE_00393 0.24 0.24 0.26 22 47809 71 4 60 7 71
ASE_00394 0.56 0.55 0.57 51 46882 39 3 35 1 42
ASE_00395 0.39 0.39 0.39 33 41532 58 4 47 7 51
ASE_00396 0.13 0.13 0.14 11 41535 72 4 66 2 72
ASE_00397 0.52 0.50 0.55 52 54520 47 3 40 4 53
ASE_00398 0.59 0.56 0.62 58 55851 45 3 33 9 46
ASE_00400 0.53 0.52 0.53 55 57867 49 4 44 1 51
ASE_00401 0.58 0.57 0.58 72 76904 52 11 41 0 54
ASE_00402 0.28 0.27 0.29 23 42408 56 2 53 1 62
ASE_00403 0.49 0.47 0.51 50 55847 52 3 45 4 57
ASE_00404 0.24 0.24 0.25 20 42991 65 4 56 5 65
ASE_00406 0.25 0.24 0.26 23 48739 73 5 61 7 71
ASE_00411 0.24 0.24 0.24 21 49369 71 5 60 6 68
ASE_00412 0.57 0.55 0.60 58 58214 42 6 33 3 47
ASE_00413 0.28 0.30 0.27 24 44462 65 14 51 0 57
ASE_00415 0.41 0.41 0.42 42 54845 61 9 50 2 61
ASE_00416 0.46 0.45 0.48 57 77301 69 8 55 6 70
ASE_00419 0.72 0.68 0.76 70 54854 27 3 19 5 33
ASE_00422 0.71 0.69 0.73 65 46882 30 2 22 6 29
ASE_00423 0.65 0.65 0.65 71 56844 39 9 29 1 38
ASE_00428 0.53 0.50 0.55 63 76522 55 8 43 4 62
ASE_00430 0.68 0.66 0.71 64 46881 32 3 23 6 33
ASE_00437 0.33 0.32 0.34 43 79274 84 6 78 0 92
ASE_00441 0.82 0.76 0.89 85 64166 20 1 9 10 27
ASE_00448 0.18 0.18 0.18 20 64148 99 6 87 6 92
ASE_00451 0.42 0.41 0.44 51 70759 66 3 63 0 74
CRW_00054 0.57 0.56 0.57 257 1107367 210 22 170 18 199
CRW_00068 0.57 0.57 0.58 259 1108856 209 20 170 19 198
CRW_00140 0.49 0.49 0.48 226 1135811 256 30 211 15 237
CRW_00173 0.38 0.38 0.39 168 1082220 282 31 237 14 277
CRW_00245 0.53 0.53 0.54 240 1105883 225 26 179 20 213
CRW_00270 0.49 0.49 0.50 225 1111832 246 27 202 17 230
CRW_00271 0.69 0.67 0.71 311 1122312 152 21 107 24 151
CRW_00273 0.41 0.41 0.41 181 1085155 279 39 226 14 265
CRW_00275 0.65 0.65 0.66 296 1114820 177 28 127 22 161
CRW_00277 0.44 0.43 0.44 196 1110351 263 35 213 15 257
CRW_00278 0.41 0.40 0.42 182 1129824 270 20 230 20 268
CRW_00280 0.67 0.66 0.68 299 1117818 160 18 125 17 154
CRW_00281 0.60 0.59 0.61 274 1144893 197 27 147 23 190
CRW_00284 0.51 0.50 0.51 228 1131314 245 27 191 27 228
CRW_00285 0.68 0.67 0.69 305 1117819 160 25 111 24 153
CRW_00466 0.71 0.70 0.71 320 1116316 158 22 107 29 138
CRW_00589 0.35 0.34 0.36 153 1094035 290 40 232 18 292
CRW_00590 0.61 0.59 0.64 268 1119334 184 21 133 30 184
CRW_00591 0.56 0.56 0.56 249 1098461 218 30 163 25 197
CRW_00772 0.19 0.18 0.19 74 945610 325 42 274 9 330
CRW_00789 0.51 0.50 0.52 224 1137356 236 32 174 30 223
CRW_00849 0.47 0.47 0.47 222 1117790 269 18 230 21 248
CRW_00997 0.69 0.69 0.69 318 1135820 167 27 113 27 146
PDB_00571 0.85 0.76 0.95 19 3301 1 1 0 0 6
PDB_00703 0.65 0.61 0.69 304 1073402 166 18 121 27 191
PDB_00828 0.88 0.78 1.00 21 2464 0 0 0 0 6
PDB_00829 0.86 0.75 1.00 18 2260 0 0 0 0 6
PDB_01020 0.86 0.74 1.00 17 2261 1 0 0 1 6
PDB_01073 0.52 0.47 0.59 16 4344 12 1 10 1 18
PDB_01273 0.54 0.52 0.56 253 1117806 233 20 181 32 238
RFA_00599 0.69 0.72 0.67 80 101355 60 17 23 20 31
RFA_00601 0.51 0.54 0.50 61 99112 81 10 52 19 53
RFA_00602 0.50 0.53 0.47 61 101346 90 13 55 22 55
TMR_00017 0.49 0.47 0.51 48 67067 52 11 35 6 54
TMR_00018 0.58 0.60 0.57 55 64523 47 13 29 5 37
TMR_00038 0.18 0.19 0.18 21 71137 101 12 83 6 89
TMR_00042 0.32 0.32 0.32 31 62739 68 8 57 3 67
TMR_00046 0.42 0.43 0.41 41 62736 64 12 46 6 55
TMR_00048 0.13 0.14 0.13 13 64876 98 11 80 7 82
TMR_00080 0.25 0.26 0.24 25 70396 79 21 58 0 71
TMR_00082 0.22 0.22 0.21 21 67798 83 19 58 6 75
TMR_00123 0.60 0.58 0.63 59 66336 40 6 29 5 42
TMR_00137 0.26 0.27 0.25 24 60978 77 17 56 4 65
TMR_00142 0.45 0.46 0.45 47 70771 69 16 42 11 55
TMR_00207 0.30 0.31 0.30 32 72282 83 7 69 7 71
TMR_00257 0.51 0.52 0.50 51 67058 57 10 42 5 47
TMR_00271 0.32 0.33 0.32 30 64166 73 10 55 8 61
TMR_00332 0.31 0.31 0.31 31 67062 76 14 54 8 68
TMR_00366 0.28 0.29 0.27 29 67789 85 19 59 7 71
TMR_00378 0.33 0.34 0.32 33 67792 78 13 58 7 64
TMR_00399 0.18 0.19 0.17 18 64876 88 17 69 2 76
TMR_00404 0.20 0.22 0.18 20 67418 93 24 66 3 72
TMR_00427 0.16 0.16 0.15 16 67421 96 15 76 5 81
TMR_00443 0.41 0.42 0.41 44 67053 72 15 49 8 60
TMR_00451 0.26 0.27 0.26 24 63454 75 9 59 7 65
TMR_00458 0.10 0.11 0.10 10 63450 94 8 78 8 83
TMR_00469 0.41 0.43 0.39 43 64511 66 15 51 0 57
TMR_00472 0.30 0.32 0.28 31 64509 82 20 60 2 66
TMR_00519 0.13 0.14 0.12 13 63083 94 17 77 0 82
TMR_00520 0.23 0.23 0.23 23 63088 87 8 71 8 76
TMR_00522 0.07 0.07 0.07 7 63085 104 14 84 6 90
TMR_00528 0.26 0.26 0.27 25 63096 77 16 53 8 72
TMR_00540 0.36 0.37 0.36 38 73429 70 18 51 1 66
TMR_00568 0.36 0.37 0.36 37 60622 72 15 52 5 62
TMR_00571 0.50 0.49 0.52 49 60631 55 6 40 9 50
TMR_00580 0.27 0.26 0.28 26 60633 75 6 61 8 74
TMR_00584 0.55 0.58 0.53 56 60969 53 10 40 3 41
TMR_00586 0.27 0.27 0.27 26 60978 76 12 59 5 71
TMR_00616 0.42 0.43 0.40 43 67054 70 10 54 6 56
TMR_00699 0.45 0.45 0.44 46 67057 58 10 48 0 56
TMR_00702 0.32 0.32 0.33 32 67063 70 8 58 4 68
TMR_00703 0.41 0.41 0.41 41 67427 62 9 51 2 58

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.