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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(20) - scored higher in this pairwise comparison

  4. Performance of PknotsRG - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(20) & PknotsRG [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(20) PknotsRG
MCC 0.782 > 0.482
Average MCC ± 95% Confidence Intervals 0.742 ± 0.012 > 0.501 ± 0.019
Sensitivity 0.667 > 0.474
Positive Predictive Value 0.917 > 0.490
Total TP 28597 > 20336
Total TN 65129029 > 65118710
Total FP 3706 < 22986
Total FP CONTRA 628 < 2798
Total FP INCONS 1968 < 18378
Total FP COMP 1110 < 1810
Total FN 14305 < 22566
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of CentroidAlifold(20) and PknotsRG. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(20) and PknotsRG).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for CentroidAlifold(20) and PknotsRG).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(20) and PknotsRG. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(20) and PknotsRG).

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Performance of CentroidAlifold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(20)

Total Base Pair Counts
Total TP 28597
Total TN 65129029
Total FP 3706
Total FP CONTRA 628
Total FP INCONS 1968
Total FP COMP 1110
Total FN 14305
Total Scores
MCC 0.782
Average MCC ± 95% Confidence Intervals 0.742 ± 0.012
Sensitivity 0.667
Positive Predictive Value 0.917
Nr of predictions 255

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2. Individual counts for CentroidAlifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.56 0.41 0.75 40 47842 13 0 13 0 57
ASE_00005 0.74 0.56 0.97 66 57902 2 0 2 0 51
ASE_00006 0.66 0.49 0.88 46 47534 6 0 6 0 47
ASE_00007 0.84 0.73 0.96 80 59602 3 0 3 0 30
ASE_00012 0.71 0.56 0.90 69 73843 11 2 6 3 54
ASE_00018 0.76 0.60 0.95 81 80516 4 1 3 0 53
ASE_00020 0.60 0.41 0.87 52 73860 8 5 3 0 74
ASE_00021 0.55 0.36 0.86 57 104130 12 2 7 3 103
ASE_00022 0.79 0.63 1.00 78 82950 4 0 0 4 46
ASE_00028 0.74 0.55 1.00 69 84597 3 0 0 3 57
ASE_00035 0.71 0.55 0.93 65 70430 8 0 5 3 53
ASE_00037 0.80 0.65 1.00 71 59269 1 0 0 1 39
ASE_00038 0.76 0.58 1.00 59 53569 0 0 0 0 42
ASE_00040 0.80 0.66 0.97 88 78912 5 0 3 2 45
ASE_00041 0.77 0.66 0.90 71 57551 8 0 8 0 37
ASE_00042 0.60 0.44 0.81 64 90021 15 0 15 0 81
ASE_00044 0.83 0.70 0.99 74 54540 1 0 1 0 31
ASE_00064 0.79 0.65 0.97 58 45391 2 0 2 0 31
ASE_00068 0.59 0.41 0.85 35 37634 6 0 6 0 50
ASE_00074 0.79 0.63 1.00 75 67821 1 0 0 1 44
ASE_00075 0.56 0.35 0.89 57 108747 12 1 6 5 105
ASE_00077 0.78 0.65 0.93 56 45090 4 1 3 0 30
ASE_00078 0.84 0.71 1.00 59 43012 0 0 0 0 24
ASE_00080 0.46 0.32 0.67 39 71573 19 1 18 0 84
ASE_00081 0.77 0.60 0.98 58 49711 1 0 1 0 39
ASE_00082 0.69 0.49 0.98 57 70442 7 0 1 6 59
ASE_00083 0.73 0.55 0.98 60 62420 1 0 1 0 50
ASE_00084 0.77 0.61 0.97 60 53566 2 1 1 0 39
ASE_00087 0.61 0.39 0.97 56 88352 2 0 2 0 88
ASE_00090 0.76 0.58 1.00 59 55552 0 0 0 0 42
ASE_00092 0.71 0.52 0.97 59 63485 2 1 1 0 54
ASE_00099 0.83 0.68 1.00 82 64538 0 0 0 0 38
ASE_00104 0.79 0.64 0.97 76 64183 2 0 2 0 43
ASE_00105 0.53 0.37 0.76 41 64207 13 2 11 0 70
ASE_00107 0.78 0.65 0.95 82 73067 4 0 4 0 45
ASE_00115 0.77 0.60 0.98 61 54553 1 0 1 0 40
ASE_00118 0.68 0.49 0.94 50 60673 4 1 2 1 52
ASE_00119 0.64 0.43 0.96 46 62787 2 1 1 0 62
ASE_00123 0.75 0.60 0.94 51 38449 3 1 2 0 34
ASE_00125 0.71 0.50 1.00 44 39296 0 0 0 0 44
ASE_00126 0.80 0.65 1.00 53 40417 1 0 0 1 29
ASE_00128 0.76 0.58 1.00 58 53243 0 0 0 0 42
ASE_00129 0.75 0.57 1.00 63 62772 0 0 0 0 48
ASE_00131 0.73 0.53 1.00 45 39295 0 0 0 0 40
ASE_00134 0.74 0.61 0.89 58 50338 7 0 7 0 37
ASE_00135 0.58 0.43 0.78 47 63130 13 0 13 0 62
ASE_00136 0.77 0.62 0.95 57 48145 3 0 3 0 35
ASE_00137 0.68 0.51 0.91 50 48461 6 0 5 1 48
ASE_00138 0.82 0.69 0.98 56 40413 1 1 0 0 25
ASE_00140 0.60 0.40 0.91 50 70821 5 3 2 0 75
ASE_00142 0.82 0.69 0.97 84 67074 5 0 3 2 38
ASE_00146 0.81 0.68 0.97 84 70789 3 0 3 0 40
ASE_00153 0.34 0.26 0.45 19 57588 23 4 19 0 54
ASE_00163 0.78 0.63 0.97 59 53240 2 1 1 0 34
ASE_00165 0.73 0.54 0.98 55 52919 2 0 1 1 46
ASE_00170 0.75 0.62 0.91 58 48764 6 1 5 0 35
ASE_00171 0.79 0.63 0.98 59 48456 2 0 1 1 35
ASE_00172 0.69 0.51 0.95 54 58939 3 2 1 0 52
ASE_00174 0.60 0.44 0.83 48 61017 10 1 9 0 61
ASE_00175 0.66 0.51 0.86 55 59967 9 1 8 0 52
ASE_00179 0.74 0.60 0.93 50 44199 5 2 2 1 34
ASE_00180 0.74 0.57 0.97 57 51301 2 1 1 0 43
ASE_00181 0.71 0.54 0.93 57 57569 6 1 3 2 49
ASE_00182 0.62 0.41 0.93 56 84195 4 1 3 0 80
ASE_00183 0.70 0.51 0.97 58 61365 2 1 1 0 55
ASE_00184 0.76 0.59 0.98 60 54554 1 0 1 0 42
ASE_00185 0.63 0.41 0.96 53 73481 2 1 1 0 75
ASE_00186 0.71 0.55 0.91 73 78923 10 0 7 3 59
ASE_00190 0.75 0.56 1.00 50 45401 2 0 0 2 40
ASE_00197 0.66 0.50 0.87 72 89170 12 0 11 1 73
ASE_00198 0.76 0.60 0.97 61 52587 2 0 2 0 41
ASE_00203 0.76 0.58 0.98 56 46608 1 0 1 0 40
ASE_00212 0.63 0.45 0.88 67 93885 10 0 9 1 81
ASE_00214 0.72 0.54 0.97 56 56222 3 1 1 1 47
ASE_00215 0.56 0.37 0.84 37 48472 7 0 7 0 62
ASE_00216 0.82 0.67 1.00 55 39285 0 0 0 0 27
ASE_00217 0.82 0.69 0.98 62 40407 2 0 1 1 28
ASE_00221 0.84 0.73 0.97 85 64532 3 0 3 0 32
ASE_00228 0.74 0.62 0.88 53 46911 8 3 4 1 33
ASE_00229 0.77 0.60 0.98 52 42433 3 0 1 2 35
ASE_00231 0.64 0.48 0.87 46 47842 7 0 7 0 50
ASE_00232 0.81 0.68 0.97 57 38444 2 2 0 0 27
ASE_00234 0.58 0.42 0.82 54 75400 12 5 7 0 75
ASE_00238 0.55 0.40 0.75 46 64200 15 3 12 0 68
ASE_00241 0.84 0.72 0.97 63 43891 2 0 2 0 24
ASE_00242 0.87 0.77 0.99 86 60988 3 0 1 2 26
ASE_00248 0.84 0.72 0.99 82 62398 2 0 1 1 32
ASE_00254 0.83 0.70 0.98 57 36798 1 0 1 0 25
ASE_00255 0.57 0.41 0.79 53 74624 14 0 14 0 77
ASE_00257 0.66 0.51 0.86 49 50983 8 2 6 0 48
ASE_00263 0.72 0.53 0.98 63 70436 1 1 0 0 57
ASE_00267 0.82 0.67 1.00 59 45091 1 0 0 1 29
ASE_00270 0.56 0.35 0.90 45 72340 6 0 5 1 83
ASE_00274 0.65 0.47 0.91 48 55558 5 3 2 0 55
ASE_00277 0.62 0.47 0.83 43 48153 9 2 7 0 48
ASE_00279 0.78 0.63 0.96 64 53234 3 0 3 0 37
ASE_00280 0.76 0.59 0.97 58 51943 2 1 1 0 40
ASE_00281 0.80 0.67 0.97 59 44490 2 0 2 0 29
ASE_00282 0.71 0.50 1.00 64 77751 0 0 0 0 63
ASE_00283 0.72 0.54 0.97 58 61716 2 0 2 0 49
ASE_00284 0.74 0.56 0.98 60 58250 1 0 1 0 48
ASE_00285 0.73 0.56 0.94 68 68934 4 2 2 0 54
ASE_00286 0.79 0.64 0.98 59 46605 1 0 1 0 33
ASE_00287 0.67 0.53 0.83 55 54880 11 0 11 0 48
ASE_00292 0.80 0.65 0.98 90 81718 3 0 2 1 48
ASE_00294 0.71 0.52 0.96 89 114388 5 0 4 1 82
ASE_00296 0.72 0.57 0.92 82 91717 8 1 6 1 63
ASE_00297 0.59 0.43 0.82 42 52924 9 2 7 0 56
ASE_00298 0.72 0.54 0.97 61 67465 2 1 1 0 52
ASE_00318 0.79 0.63 0.99 74 80125 8 0 1 7 44
ASE_00328 0.78 0.62 0.99 69 72701 6 0 1 5 43
ASE_00332 0.71 0.54 0.94 74 81731 5 0 5 0 64
ASE_00335 0.74 0.59 0.92 69 75391 13 0 6 7 47
ASE_00340 0.75 0.61 0.93 52 46000 8 0 4 4 33
ASE_00342 0.86 0.75 0.99 86 62394 1 0 1 0 29
ASE_00353 0.70 0.50 0.98 54 57915 2 1 0 1 53
ASE_00361 0.65 0.42 1.00 53 75413 0 0 0 0 74
ASE_00362 0.76 0.58 0.98 53 48151 2 0 1 1 38
ASE_00363 0.71 0.56 0.88 53 51300 7 0 7 0 41
ASE_00364 0.69 0.53 0.89 56 54222 7 1 6 0 49
ASE_00366 0.72 0.58 0.89 57 58589 7 1 6 0 41
ASE_00367 0.84 0.71 1.00 61 43010 1 0 0 1 25
ASE_00369 0.77 0.60 0.98 64 55880 1 0 1 0 43
ASE_00370 0.76 0.60 0.96 50 41853 2 0 2 0 34
ASE_00372 0.75 0.57 0.98 57 51945 1 0 1 0 43
ASE_00374 0.81 0.66 1.00 58 44792 0 0 0 0 30
ASE_00376 0.72 0.55 0.94 58 56891 4 0 4 0 47
ASE_00377 0.66 0.50 0.88 53 57570 7 1 6 0 54
ASE_00379 0.76 0.61 0.96 54 46000 3 1 1 1 35
ASE_00382 0.85 0.73 0.98 61 41843 2 0 1 1 23
ASE_00383 0.77 0.59 1.00 62 54553 0 0 0 0 43
ASE_00384 0.77 0.62 0.97 57 48457 2 1 1 0 35
ASE_00386 0.74 0.56 0.98 54 50348 1 0 1 0 42
ASE_00387 0.66 0.49 0.88 51 55887 7 0 7 0 53
ASE_00388 0.78 0.62 0.98 55 45697 2 0 1 1 34
ASE_00390 0.77 0.65 0.92 55 42135 5 2 3 0 30
ASE_00393 0.72 0.58 0.90 54 47835 6 0 6 0 39
ASE_00394 0.79 0.63 0.98 59 46911 1 0 1 0 34
ASE_00395 0.76 0.63 0.91 53 41558 5 0 5 0 31
ASE_00396 0.82 0.69 0.98 57 41558 1 0 1 0 26
ASE_00397 0.74 0.54 1.00 57 54558 0 0 0 0 48
ASE_00398 0.71 0.52 0.96 54 55889 2 0 2 0 50
ASE_00400 0.77 0.60 0.98 64 57905 2 0 1 1 42
ASE_00401 0.65 0.44 0.95 56 76969 3 1 2 0 70
ASE_00402 0.79 0.62 1.00 53 42433 0 0 0 0 32
ASE_00403 0.75 0.57 0.98 61 55883 1 0 1 0 46
ASE_00404 0.80 0.66 0.98 56 43014 2 0 1 1 29
ASE_00406 0.77 0.61 0.98 57 48770 1 0 1 0 37
ASE_00411 0.65 0.54 0.77 48 49393 14 6 8 0 41
ASE_00412 0.54 0.40 0.72 42 58253 16 2 14 0 63
ASE_00413 0.77 0.64 0.93 52 44495 5 3 1 1 29
ASE_00415 0.55 0.39 0.78 40 54895 11 0 11 0 63
ASE_00416 0.73 0.58 0.93 74 77341 6 1 5 0 53
ASE_00419 0.69 0.54 0.88 56 54882 8 3 5 0 47
ASE_00422 0.69 0.56 0.84 53 46908 11 0 10 1 41
ASE_00423 0.76 0.66 0.88 72 56871 11 0 10 1 37
ASE_00428 0.76 0.64 0.90 80 76547 9 1 8 0 45
ASE_00430 0.74 0.57 0.96 55 46914 2 0 2 0 42
ASE_00437 0.56 0.46 0.68 62 79310 29 0 29 0 73
ASE_00441 0.62 0.41 0.94 46 64212 4 0 3 1 66
ASE_00448 0.81 0.71 0.94 79 64177 5 0 5 0 33
ASE_00451 0.79 0.66 0.95 82 70790 4 0 4 0 43
CRW_00024 0.91 0.86 0.95 394 1085188 51 6 13 32 64
CRW_00034 0.83 0.77 0.90 365 1141911 54 9 31 14 109
CRW_00048 0.86 0.80 0.93 374 1170812 45 10 19 16 96
CRW_00054 0.86 0.80 0.93 364 1107423 43 10 19 14 92
CRW_00059 0.85 0.78 0.93 368 1172351 42 9 18 15 105
CRW_00061 0.86 0.80 0.92 380 1181542 47 10 21 16 96
CRW_00068 0.85 0.80 0.91 365 1108906 48 11 23 14 92
CRW_00096 0.86 0.78 0.95 363 1178497 43 4 16 23 102
CRW_00140 0.86 0.80 0.92 372 1135875 46 11 20 15 91
CRW_00141 0.85 0.78 0.93 371 1201625 47 10 19 18 105
CRW_00150 0.86 0.80 0.92 372 1152515 48 10 24 14 94
CRW_00152 0.84 0.77 0.91 364 1180015 52 13 24 15 107
CRW_00166 0.86 0.78 0.94 364 1190809 45 4 19 22 104
CRW_00173 0.80 0.75 0.86 332 1082272 67 11 41 15 113
CRW_00177 0.83 0.75 0.92 356 1178493 48 7 24 17 117
CRW_00196 0.86 0.79 0.94 377 1207832 45 8 18 19 98
CRW_00230 0.86 0.79 0.94 378 1198524 39 8 16 15 100
CRW_00245 0.87 0.81 0.93 367 1105932 46 9 20 17 86
CRW_00248 0.85 0.77 0.92 375 1218735 46 11 20 15 109
CRW_00250 0.84 0.77 0.92 370 1198524 46 11 21 14 108
CRW_00256 0.84 0.77 0.91 360 1192345 51 10 25 16 108
CRW_00270 0.86 0.80 0.92 362 1111893 46 11 20 15 93
CRW_00271 0.84 0.77 0.91 355 1122363 48 8 25 15 107
CRW_00273 0.86 0.79 0.92 354 1085218 46 8 21 17 92
CRW_00275 0.87 0.81 0.93 371 1114870 46 9 21 16 86
CRW_00277 0.85 0.78 0.91 354 1110408 50 12 21 17 99
CRW_00278 0.84 0.78 0.91 351 1129869 54 7 29 18 99
CRW_00279 0.84 0.77 0.92 357 1180030 50 8 21 21 107
CRW_00280 0.84 0.79 0.89 357 1117860 63 9 34 20 96
CRW_00281 0.84 0.77 0.92 357 1144951 49 9 24 16 107
CRW_00284 0.84 0.77 0.91 350 1131377 50 7 26 17 106
CRW_00285 0.83 0.77 0.90 353 1117869 56 11 27 18 105
CRW_00289 0.82 0.75 0.91 356 1189260 53 9 28 16 120
CRW_00466 0.86 0.79 0.93 364 1116372 45 9 20 16 94
CRW_00589 0.86 0.78 0.94 347 1094091 45 2 20 23 98
CRW_00590 0.86 0.79 0.93 359 1119369 53 3 25 25 93
CRW_00591 0.86 0.79 0.92 354 1098520 55 6 23 26 92
CRW_00772 0.79 0.73 0.85 295 945652 81 5 48 28 109
CRW_00789 0.83 0.76 0.91 340 1137411 63 5 30 28 107
CRW_00795 0.80 0.72 0.88 284 1152598 97 3 36 58 110
CRW_00849 0.82 0.76 0.88 357 1117854 65 10 39 16 113
CRW_00997 0.85 0.80 0.91 369 1135873 50 13 23 14 95
PDB_00571 0.87 0.80 0.95 20 3300 1 1 0 0 5
PDB_00703 0.81 0.70 0.92 348 1073468 55 8 21 26 147
PDB_00828 0.88 0.78 1.00 21 2464 0 0 0 0 6
PDB_00829 0.86 0.75 1.00 18 2260 0 0 0 0 6
PDB_01020 0.86 0.74 1.00 17 2261 1 0 0 1 6
PDB_01073 0.84 0.71 1.00 24 4347 1 0 0 1 10
PDB_01105 0.78 0.66 0.92 359 1433581 59 2 29 28 181
PDB_01120 0.79 0.68 0.92 357 1204739 53 7 25 21 170
PDB_01273 0.80 0.69 0.91 341 1117886 62 6 27 29 150
RFA_00599 0.89 0.83 0.96 92 101379 9 1 3 5 19
RFA_00601 0.90 0.86 0.93 98 99130 13 1 6 6 16
RFA_00602 0.87 0.84 0.91 97 101368 18 1 9 8 19
TMR_00017 0.80 0.65 0.99 66 67094 1 0 1 0 36
TMR_00018 0.65 0.54 0.78 50 64556 15 5 9 1 42
TMR_00038 0.68 0.56 0.82 62 71177 15 5 9 1 48
TMR_00042 0.66 0.53 0.83 52 62772 12 4 7 1 46
TMR_00046 0.53 0.45 0.63 43 62767 26 4 21 1 53
TMR_00048 0.66 0.53 0.82 50 64919 12 7 4 1 45
TMR_00080 0.63 0.52 0.77 50 70435 15 8 7 0 46
TMR_00082 0.66 0.56 0.78 54 67827 18 7 8 3 42
TMR_00123 0.79 0.64 0.97 65 66363 3 1 1 1 36
TMR_00137 0.68 0.55 0.83 49 61016 13 6 4 3 40
TMR_00142 0.65 0.46 0.92 47 70825 11 0 4 7 55
TMR_00207 0.74 0.57 0.97 59 72329 4 1 1 2 44
TMR_00257 0.78 0.64 0.94 63 67094 4 4 0 0 35
TMR_00271 0.55 0.44 0.68 40 64202 24 6 13 5 51
TMR_00332 0.67 0.48 0.92 48 67109 5 1 3 1 51
TMR_00366 0.70 0.49 1.00 49 67847 7 0 0 7 51
TMR_00378 0.63 0.46 0.87 45 67844 15 1 6 8 52
TMR_00399 0.60 0.49 0.74 46 64918 16 6 10 0 48
TMR_00404 0.60 0.50 0.72 46 67464 21 3 15 3 46
TMR_00427 0.63 0.45 0.86 44 67477 8 7 0 1 53
TMR_00443 0.73 0.58 0.92 60 67096 6 0 5 1 44
TMR_00451 0.63 0.55 0.73 49 63479 20 10 8 2 40
TMR_00458 0.65 0.54 0.79 50 63483 15 6 7 2 43
TMR_00469 0.79 0.69 0.91 69 64544 10 6 1 3 31
TMR_00472 0.72 0.64 0.82 62 64544 15 7 7 1 35
TMR_00519 0.63 0.53 0.75 50 63123 19 5 12 2 45
TMR_00520 0.63 0.48 0.81 48 63131 13 3 8 2 51
TMR_00522 0.62 0.47 0.82 46 63134 15 4 6 5 51
TMR_00528 0.67 0.54 0.84 52 63128 15 4 6 5 45
TMR_00540 0.60 0.45 0.81 47 73478 11 4 7 0 57
TMR_00568 0.77 0.68 0.87 67 60649 15 1 9 5 32
TMR_00571 0.80 0.71 0.91 70 60649 12 1 6 5 29
TMR_00580 0.78 0.68 0.89 68 60650 13 2 6 5 32
TMR_00584 0.80 0.70 0.91 68 61000 10 3 4 3 29
TMR_00586 0.74 0.66 0.83 64 60998 18 6 7 5 33
TMR_00616 0.74 0.65 0.85 64 67086 12 7 4 1 35
TMR_00699 0.66 0.49 0.89 50 67105 6 1 5 0 52
TMR_00702 0.60 0.45 0.79 45 67104 12 2 10 0 55
TMR_00703 0.71 0.57 0.90 56 67466 6 2 4 0 43

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Performance of PknotsRG - scored lower in this pairwise comparison

1. Total counts & total scores for PknotsRG

Total Base Pair Counts
Total TP 20336
Total TN 65118710
Total FP 22986
Total FP CONTRA 2798
Total FP INCONS 18378
Total FP COMP 1810
Total FN 22566
Total Scores
MCC 0.482
Average MCC ± 95% Confidence Intervals 0.501 ± 0.019
Sensitivity 0.474
Positive Predictive Value 0.490
Nr of predictions 255

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2. Individual counts for PknotsRG [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.70 0.71 0.70 69 47796 32 9 21 2 28
ASE_00005 0.63 0.58 0.68 68 57870 38 0 32 6 49
ASE_00006 0.57 0.58 0.57 54 47491 44 7 34 3 39
ASE_00007 0.57 0.55 0.61 60 59586 43 1 38 4 50
ASE_00012 0.58 0.54 0.61 67 73811 49 2 40 7 56
ASE_00018 0.80 0.76 0.84 102 80479 22 3 17 2 32
ASE_00020 0.53 0.52 0.53 66 73796 58 8 50 0 60
ASE_00021 0.57 0.54 0.61 86 104056 61 7 47 7 74
ASE_00022 0.46 0.44 0.48 54 82915 65 6 53 6 70
ASE_00028 0.59 0.56 0.61 71 84550 53 4 41 8 55
ASE_00035 0.30 0.28 0.32 33 70398 76 11 58 7 85
ASE_00037 0.24 0.23 0.25 25 59239 79 3 73 3 85
ASE_00038 0.55 0.54 0.56 55 53529 45 4 40 1 46
ASE_00040 0.50 0.47 0.52 63 78882 64 5 53 6 70
ASE_00041 0.52 0.50 0.55 54 57532 48 2 42 4 54
ASE_00042 0.53 0.50 0.58 72 89975 54 3 50 1 73
ASE_00044 0.69 0.68 0.70 71 54513 35 3 28 4 34
ASE_00064 0.43 0.43 0.44 38 45364 53 5 44 4 51
ASE_00068 0.24 0.24 0.25 20 37596 59 5 54 0 65
ASE_00074 0.58 0.57 0.59 68 67781 47 6 41 0 51
ASE_00075 0.65 0.59 0.71 96 108676 46 2 37 7 66
ASE_00077 0.25 0.24 0.25 21 45067 67 7 55 5 65
ASE_00078 0.68 0.67 0.68 56 42989 31 5 21 5 27
ASE_00080 0.46 0.44 0.48 54 71519 61 5 53 3 69
ASE_00081 0.53 0.53 0.54 51 49676 44 5 38 1 46
ASE_00082 0.50 0.47 0.54 54 70400 60 1 45 14 62
ASE_00083 0.79 0.75 0.83 82 62382 26 2 15 9 28
ASE_00084 0.70 0.69 0.72 68 53534 29 6 20 3 31
ASE_00087 0.61 0.58 0.65 83 88283 49 5 39 5 61
ASE_00090 0.59 0.59 0.59 60 55509 47 2 40 5 41
ASE_00092 0.73 0.70 0.76 79 63442 30 0 25 5 34
ASE_00099 0.51 0.50 0.53 60 64506 56 6 48 2 60
ASE_00104 0.65 0.63 0.68 75 64151 36 3 32 1 44
ASE_00105 0.38 0.36 0.40 40 64160 66 9 52 5 71
ASE_00107 0.47 0.45 0.50 57 73039 57 2 55 0 70
ASE_00115 0.48 0.47 0.49 47 54520 56 1 47 8 54
ASE_00118 0.45 0.44 0.45 45 60627 57 4 50 3 57
ASE_00119 0.67 0.65 0.69 70 62734 33 1 30 2 38
ASE_00123 0.40 0.39 0.42 33 38424 50 2 44 4 52
ASE_00125 0.64 0.63 0.65 55 39255 30 4 26 0 33
ASE_00126 0.79 0.79 0.78 65 40387 21 3 15 3 17
ASE_00128 0.76 0.73 0.80 73 53210 25 2 16 7 27
ASE_00129 0.52 0.50 0.53 56 62730 53 5 44 4 55
ASE_00131 0.64 0.58 0.72 49 39272 29 0 19 10 36
ASE_00134 0.56 0.57 0.55 54 50305 49 4 40 5 41
ASE_00135 0.47 0.46 0.48 50 63085 59 8 47 4 59
ASE_00136 0.49 0.47 0.51 43 48121 50 1 40 9 49
ASE_00137 0.44 0.43 0.45 42 48423 53 5 46 2 56
ASE_00138 0.53 0.52 0.55 42 40393 35 4 31 0 39
ASE_00140 0.69 0.65 0.74 81 70767 33 3 25 5 44
ASE_00142 0.74 0.70 0.79 85 67054 26 4 18 4 37
ASE_00146 0.51 0.46 0.56 57 70775 47 0 44 3 67
ASE_00153 0.61 0.62 0.61 45 57556 71 2 27 42 28
ASE_00163 0.29 0.29 0.30 27 53211 72 7 56 9 66
ASE_00165 0.57 0.55 0.60 56 52881 39 7 31 1 45
ASE_00170 0.70 0.68 0.72 63 48741 25 2 22 1 30
ASE_00171 0.71 0.70 0.73 66 48425 25 5 20 0 28
ASE_00172 0.68 0.66 0.70 70 58896 35 4 26 5 36
ASE_00174 0.55 0.51 0.59 56 60980 39 3 36 0 53
ASE_00175 0.44 0.44 0.45 47 59926 62 6 52 4 60
ASE_00179 0.64 0.65 0.62 55 44164 34 7 27 0 29
ASE_00180 0.72 0.69 0.75 69 51268 29 2 21 6 31
ASE_00181 0.54 0.53 0.55 56 57528 50 3 43 4 50
ASE_00182 0.49 0.47 0.51 64 84129 65 6 56 3 72
ASE_00183 0.72 0.71 0.73 80 61316 33 2 27 4 33
ASE_00184 0.63 0.64 0.63 65 54511 39 10 29 0 37
ASE_00185 0.61 0.59 0.65 75 73420 43 5 36 2 53
ASE_00186 0.74 0.70 0.78 92 78885 31 3 23 5 40
ASE_00190 0.46 0.44 0.47 40 45366 45 8 37 0 50
ASE_00197 0.48 0.46 0.51 66 89124 66 4 59 3 79
ASE_00198 0.54 0.53 0.55 54 52551 45 6 39 0 48
ASE_00203 0.70 0.68 0.72 65 46575 29 6 19 4 31
ASE_00212 0.54 0.52 0.55 77 93822 66 5 57 4 71
ASE_00214 0.78 0.76 0.80 78 56182 28 3 17 8 25
ASE_00215 0.55 0.53 0.57 52 48425 42 4 35 3 47
ASE_00216 0.60 0.61 0.60 50 39256 36 8 26 2 32
ASE_00217 0.30 0.29 0.32 26 40388 60 6 50 4 64
ASE_00221 0.40 0.38 0.42 45 64514 65 3 58 4 72
ASE_00228 0.59 0.59 0.58 51 46883 37 14 23 0 35
ASE_00229 0.58 0.57 0.59 50 42401 39 5 30 4 37
ASE_00231 0.69 0.69 0.70 66 47801 28 5 23 0 30
ASE_00232 0.56 0.55 0.57 46 38422 38 3 32 3 38
ASE_00234 0.52 0.49 0.55 63 75351 56 2 50 4 66
ASE_00238 0.48 0.47 0.50 54 64152 58 4 51 3 60
ASE_00241 0.56 0.54 0.58 47 43875 43 0 34 9 40
ASE_00242 0.72 0.68 0.76 76 60975 27 3 21 3 36
ASE_00248 0.46 0.42 0.49 48 62384 49 3 46 0 66
ASE_00254 0.61 0.60 0.63 49 36778 33 5 24 4 33
ASE_00255 0.47 0.45 0.50 59 74572 60 7 53 0 71
ASE_00257 0.64 0.64 0.65 62 50944 34 0 34 0 35
ASE_00263 0.62 0.62 0.62 74 70380 47 5 41 1 46
ASE_00267 0.46 0.44 0.48 39 45069 51 5 37 9 49
ASE_00270 0.63 0.62 0.64 79 72267 45 8 36 1 49
ASE_00274 0.48 0.47 0.50 48 55515 48 8 40 0 55
ASE_00277 0.39 0.40 0.39 36 48113 58 9 47 2 55
ASE_00279 0.38 0.36 0.41 36 53213 58 1 51 6 65
ASE_00280 0.37 0.37 0.38 36 51908 62 6 53 3 62
ASE_00281 0.54 0.51 0.58 45 44473 39 0 33 6 43
ASE_00282 0.42 0.41 0.42 52 77692 72 6 65 1 75
ASE_00283 0.74 0.73 0.76 78 61673 27 5 20 2 29
ASE_00284 0.62 0.60 0.64 65 58210 43 4 32 7 43
ASE_00285 0.62 0.58 0.66 71 68899 43 2 34 7 51
ASE_00286 0.43 0.42 0.43 39 46574 61 3 49 9 53
ASE_00287 0.59 0.55 0.63 57 54855 40 0 34 6 46
ASE_00292 0.71 0.66 0.76 91 81690 34 4 25 5 47
ASE_00294 0.78 0.74 0.83 127 114328 29 3 23 3 44
ASE_00296 0.31 0.30 0.33 43 91677 88 8 78 2 102
ASE_00297 0.53 0.53 0.54 52 52878 50 3 42 5 46
ASE_00298 0.19 0.19 0.19 21 67420 90 9 78 3 92
ASE_00318 0.64 0.61 0.67 72 80092 40 13 23 4 46
ASE_00328 0.41 0.41 0.41 46 72659 73 3 63 7 66
ASE_00332 0.54 0.51 0.57 71 81686 59 2 51 6 67
ASE_00335 0.52 0.52 0.52 60 75350 64 13 43 8 56
ASE_00340 0.71 0.72 0.71 61 45970 34 7 18 9 24
ASE_00342 0.48 0.45 0.50 52 62378 51 1 50 0 63
ASE_00353 0.46 0.47 0.45 50 57860 60 11 49 0 57
ASE_00361 0.37 0.36 0.38 46 75345 78 9 66 3 81
ASE_00362 0.62 0.62 0.63 56 48116 36 6 27 3 35
ASE_00363 0.54 0.55 0.53 52 51262 46 5 41 0 42
ASE_00364 0.32 0.31 0.33 33 54184 72 7 61 4 72
ASE_00366 0.52 0.54 0.50 53 58547 55 12 41 2 45
ASE_00367 0.33 0.35 0.32 30 42976 65 8 57 0 56
ASE_00369 0.68 0.67 0.69 72 55841 37 2 30 5 35
ASE_00370 0.65 0.63 0.66 53 41825 27 5 22 0 31
ASE_00372 0.72 0.71 0.72 71 51905 30 5 22 3 29
ASE_00374 0.56 0.56 0.57 49 44764 37 8 29 0 39
ASE_00376 0.52 0.50 0.54 53 56855 48 4 41 3 52
ASE_00377 0.69 0.66 0.72 71 57531 34 3 25 6 36
ASE_00379 0.44 0.44 0.45 39 45969 55 7 41 7 50
ASE_00382 0.51 0.51 0.52 43 41822 43 6 34 3 41
ASE_00383 0.44 0.43 0.45 45 54516 59 4 50 5 60
ASE_00384 0.73 0.71 0.75 65 48429 27 4 18 5 27
ASE_00386 0.53 0.53 0.53 51 50306 51 4 42 5 45
ASE_00387 0.36 0.37 0.35 38 55837 70 6 64 0 66
ASE_00388 0.68 0.67 0.69 60 45666 32 1 26 5 29
ASE_00390 0.50 0.48 0.53 41 42117 44 6 31 7 44
ASE_00393 0.36 0.34 0.38 32 47810 59 3 50 6 61
ASE_00394 0.72 0.72 0.73 67 46879 28 3 22 3 26
ASE_00395 0.51 0.49 0.53 41 41539 45 1 35 9 43
ASE_00396 0.37 0.36 0.38 30 41536 55 5 45 5 53
ASE_00397 0.52 0.51 0.52 54 54511 50 7 43 0 51
ASE_00398 0.64 0.62 0.66 64 55848 36 1 32 3 40
ASE_00400 0.53 0.52 0.54 55 57868 48 5 42 1 51
ASE_00401 0.55 0.56 0.54 70 76898 60 13 47 0 56
ASE_00402 0.60 0.59 0.61 50 42404 35 4 28 3 35
ASE_00403 0.47 0.44 0.50 47 55851 51 3 44 4 60
ASE_00404 0.56 0.55 0.56 47 42987 42 0 37 5 38
ASE_00406 0.69 0.66 0.72 62 48742 33 2 22 9 32
ASE_00411 0.26 0.27 0.26 24 49362 69 12 57 0 65
ASE_00412 0.38 0.37 0.39 39 58212 60 13 47 0 66
ASE_00413 0.46 0.49 0.43 40 44457 54 14 40 0 41
ASE_00415 0.51 0.51 0.51 53 54843 52 7 43 2 50
ASE_00416 0.71 0.68 0.75 86 77306 36 1 28 7 41
ASE_00419 0.76 0.73 0.80 75 54852 23 4 15 4 28
ASE_00422 0.48 0.47 0.49 44 46881 51 5 41 5 50
ASE_00423 0.49 0.49 0.50 53 56847 56 9 44 3 56
ASE_00428 0.54 0.52 0.57 65 76521 54 5 45 4 60
ASE_00430 0.63 0.61 0.66 59 46881 36 5 26 5 38
ASE_00437 0.42 0.41 0.44 55 79275 71 4 67 0 80
ASE_00441 0.78 0.74 0.83 83 64161 28 1 16 11 29
ASE_00448 0.22 0.22 0.23 25 64151 91 6 79 6 87
ASE_00451 0.50 0.47 0.52 59 70763 57 3 51 3 66
CRW_00024 0.77 0.76 0.79 348 1085160 130 18 75 37 110
CRW_00034 0.63 0.63 0.63 300 1141843 196 31 142 23 174
CRW_00048 0.45 0.45 0.45 210 1170748 276 27 230 19 260
CRW_00054 0.53 0.52 0.54 236 1107378 216 34 168 14 220
CRW_00059 0.50 0.49 0.51 233 1172293 234 28 192 14 240
CRW_00061 0.43 0.44 0.43 208 1181469 284 32 244 8 268
CRW_00068 0.33 0.33 0.34 152 1108852 312 37 264 11 305
CRW_00096 0.55 0.55 0.55 255 1178420 227 21 184 22 210
CRW_00140 0.64 0.64 0.65 296 1135820 182 22 140 20 167
CRW_00141 0.51 0.50 0.52 238 1201566 240 29 192 19 238
CRW_00150 0.41 0.41 0.42 190 1152467 282 34 230 18 276
CRW_00152 0.51 0.50 0.52 236 1179961 240 37 182 21 235
CRW_00166 0.53 0.52 0.54 242 1190746 234 25 183 26 226
CRW_00173 0.29 0.29 0.29 128 1082212 325 37 279 9 317
CRW_00177 0.42 0.41 0.42 196 1178413 284 31 240 13 277
CRW_00196 0.47 0.46 0.47 220 1207767 270 26 222 22 255
CRW_00230 0.55 0.54 0.57 260 1198467 221 30 169 22 218
CRW_00245 0.35 0.35 0.34 157 1105872 312 45 254 13 296
CRW_00248 0.57 0.57 0.58 275 1218668 230 24 174 32 209
CRW_00250 0.43 0.43 0.43 205 1198449 287 30 242 15 273
CRW_00256 0.45 0.44 0.46 206 1192291 257 41 202 14 262
CRW_00270 0.38 0.37 0.39 168 1111857 279 39 222 18 287
CRW_00271 0.49 0.48 0.50 220 1122307 239 36 188 15 242
CRW_00273 0.51 0.50 0.51 222 1085169 227 31 179 17 224
CRW_00275 0.42 0.42 0.43 193 1114817 278 26 235 17 264
CRW_00277 0.25 0.25 0.24 113 1110332 354 55 295 4 340
CRW_00278 0.41 0.40 0.42 180 1129825 270 35 216 19 270
CRW_00279 0.29 0.29 0.30 134 1179968 334 40 274 20 330
CRW_00280 0.50 0.50 0.51 226 1117813 234 28 193 13 227
CRW_00281 0.30 0.30 0.30 138 1144878 340 40 285 15 326
CRW_00284 0.26 0.25 0.26 115 1131320 336 35 290 11 341
CRW_00285 0.47 0.47 0.47 214 1117807 257 31 208 18 244
CRW_00289 0.45 0.44 0.46 209 1189197 272 34 213 25 267
CRW_00466 0.61 0.60 0.62 273 1116325 194 25 142 27 185
CRW_00589 0.22 0.21 0.22 95 1094029 351 37 299 15 350
CRW_00590 0.32 0.31 0.33 141 1119330 303 41 244 18 311
CRW_00591 0.61 0.60 0.62 267 1098475 190 19 142 29 179
CRW_00772 0.24 0.24 0.25 97 945607 320 41 255 24 307
CRW_00789 0.35 0.35 0.35 156 1137342 304 48 240 16 291
CRW_00795 0.24 0.25 0.23 98 1152503 357 51 269 37 296
CRW_00849 0.48 0.48 0.49 225 1117798 260 25 212 23 245
CRW_00997 0.52 0.52 0.52 239 1135819 238 24 196 18 225
PDB_00571 0.17 0.16 0.19 4 3300 17 6 11 0 21
PDB_00703 0.50 0.48 0.53 239 1073392 239 21 193 25 256
PDB_00828 0.88 0.78 1.00 21 2464 0 0 0 0 6
PDB_00829 0.86 0.75 1.00 18 2260 0 0 0 0 6
PDB_01020 0.23 0.22 0.26 5 2259 14 2 12 0 18
PDB_01073 0.75 0.65 0.88 22 4346 4 0 3 1 12
PDB_01105 0.51 0.50 0.52 269 1433453 278 27 222 29 271
PDB_01120 0.48 0.45 0.51 239 1204657 247 27 205 15 288
PDB_01273 0.47 0.46 0.49 225 1117799 263 23 213 27 266
RFA_00599 0.63 0.68 0.60 75 101349 70 18 33 19 36
RFA_00601 0.48 0.50 0.46 57 99111 86 21 46 19 57
RFA_00602 0.69 0.72 0.67 83 101351 61 10 31 20 33
TMR_00017 0.36 0.37 0.36 38 67055 74 15 53 6 64
TMR_00018 0.30 0.32 0.30 29 64522 75 10 59 6 63
TMR_00038 0.24 0.25 0.24 27 71141 89 12 73 4 83
TMR_00042 0.24 0.24 0.24 24 62735 79 9 67 3 74
TMR_00046 0.54 0.55 0.54 53 62736 49 11 35 3 43
TMR_00048 0.32 0.34 0.30 32 64875 78 9 64 5 63
TMR_00080 0.59 0.61 0.56 59 70395 49 16 30 3 37
TMR_00082 0.63 0.64 0.63 61 67799 41 12 24 5 35
TMR_00123 0.46 0.47 0.46 47 66327 57 11 45 1 54
TMR_00137 0.27 0.28 0.26 25 60980 78 14 56 8 64
TMR_00142 0.45 0.47 0.44 48 70767 70 15 46 9 54
TMR_00207 0.36 0.35 0.36 36 72291 70 4 59 7 67
TMR_00257 0.25 0.24 0.26 24 67068 73 8 61 4 74
TMR_00271 0.49 0.48 0.49 44 64171 54 8 38 8 47
TMR_00332 0.39 0.38 0.40 38 67065 62 9 49 4 61
TMR_00366 0.28 0.28 0.29 28 67798 83 12 58 13 72
TMR_00378 0.29 0.30 0.28 29 67791 87 7 69 11 68
TMR_00399 0.16 0.17 0.15 16 64871 97 27 66 4 78
TMR_00404 0.28 0.30 0.26 28 67421 90 22 57 11 64
TMR_00427 0.31 0.31 0.31 30 67432 71 11 55 5 67
TMR_00443 0.45 0.45 0.46 47 67058 58 14 42 2 57
TMR_00451 0.17 0.19 0.16 17 63441 88 16 72 0 72
TMR_00458 0.20 0.20 0.20 19 63449 85 19 59 7 74
TMR_00469 0.40 0.41 0.38 41 64513 66 11 55 0 59
TMR_00472 0.36 0.38 0.35 37 64514 72 24 45 3 60
TMR_00519 0.14 0.15 0.13 14 63086 100 16 74 10 81
TMR_00520 0.36 0.37 0.35 37 63085 78 13 55 10 62
TMR_00522 0.36 0.36 0.36 35 63092 72 11 52 9 62
TMR_00528 0.13 0.13 0.12 13 63082 105 12 83 10 84
TMR_00540 0.45 0.45 0.46 47 73433 65 4 52 9 57
TMR_00568 0.59 0.59 0.60 58 60630 47 3 35 9 41
TMR_00571 0.59 0.60 0.58 59 60625 47 7 35 5 40
TMR_00580 0.32 0.31 0.32 31 60630 70 13 52 5 69
TMR_00584 0.40 0.42 0.38 41 60967 72 8 59 5 56
TMR_00586 0.23 0.25 0.22 24 60964 88 18 69 1 73
TMR_00616 0.37 0.37 0.36 37 67058 71 18 48 5 62
TMR_00699 0.41 0.41 0.41 42 67059 63 10 50 3 60
TMR_00702 0.28 0.29 0.28 29 67057 80 18 57 5 71
TMR_00703 0.31 0.31 0.31 31 67427 74 16 54 4 68

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.