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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidHomfold‑LAST - scored higher in this pairwise comparison

  4. Performance of Multilign(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidHomfold‑LAST & Multilign(20) [.zip] - may take several seconds...


Overview

Metric CentroidHomfold‑LAST Multilign(20)
MCC 0.701 > 0.651
Average MCC ± 95% Confidence Intervals 0.702 ± 0.013 > 0.656 ± 0.017
Sensitivity 0.549 < 0.591
Positive Predictive Value 0.895 > 0.718
Total TP 11032 < 11862
Total TN 11499946 > 11495758
Total FP 1736 < 5464
Total FP CONTRA 228 < 615
Total FP INCONS 1063 < 4034
Total FP COMP 445 < 815
Total FN 9053 > 8223
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of CentroidHomfold-LAST and Multilign(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidHomfold‑LAST and Multilign(20)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for CentroidHomfold‑LAST and Multilign(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidHomfold-LAST and Multilign(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidHomfold‑LAST and Multilign(20)).

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Performance of CentroidHomfold‑LAST - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidHomfold‑LAST

Total Base Pair Counts
Total TP 11032
Total TN 11499946
Total FP 1736
Total FP CONTRA 228
Total FP INCONS 1063
Total FP COMP 445
Total FN 9053
Total Scores
MCC 0.701
Average MCC ± 95% Confidence Intervals 0.702 ± 0.013
Sensitivity 0.549
Positive Predictive Value 0.895
Nr of predictions 196

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2. Individual counts for CentroidHomfold‑LAST [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00005 0.81 0.67 0.98 78 57890 3 0 2 1 39
ASE_00006 0.67 0.52 0.87 48 47531 7 1 6 0 45
ASE_00007 0.79 0.65 0.95 72 59609 9 0 4 5 38
ASE_00012 0.76 0.62 0.94 76 73839 7 2 3 2 47
ASE_00018 0.82 0.70 0.95 94 80502 7 0 5 2 40
ASE_00020 0.66 0.48 0.91 60 73854 7 1 5 1 66
ASE_00021 0.67 0.47 0.96 75 104118 5 0 3 2 85
ASE_00035 0.65 0.44 0.95 52 70445 8 1 2 5 66
ASE_00037 0.78 0.65 0.94 72 59263 8 0 5 3 38
ASE_00038 0.79 0.66 0.94 67 53557 5 1 3 1 34
ASE_00040 0.64 0.44 0.94 59 78940 5 2 2 1 74
ASE_00041 0.73 0.56 0.95 61 57566 7 0 3 4 47
ASE_00042 0.74 0.58 0.93 84 90010 6 1 5 0 61
ASE_00044 0.82 0.70 0.97 73 54540 3 0 2 1 32
ASE_00064 0.75 0.61 0.93 54 45393 8 0 4 4 35
ASE_00068 0.70 0.49 1.00 42 37633 0 0 0 0 43
ASE_00074 0.76 0.62 0.94 74 67817 7 1 4 2 45
ASE_00075 0.62 0.42 0.93 68 108738 7 1 4 2 94
ASE_00077 0.77 0.65 0.90 56 45088 7 2 4 1 30
ASE_00078 0.82 0.72 0.94 60 43007 5 1 3 1 23
ASE_00080 0.48 0.30 0.77 37 71583 11 0 11 0 86
ASE_00081 0.71 0.55 0.93 53 49713 5 1 3 1 44
ASE_00082 0.44 0.22 0.89 25 70472 3 0 3 0 91
ASE_00083 0.72 0.56 0.93 62 62414 6 1 4 1 48
ASE_00084 0.73 0.62 0.87 61 53558 11 2 7 2 38
ASE_00087 0.58 0.44 0.77 63 88328 21 2 17 2 81
ASE_00090 0.69 0.60 0.78 61 55533 17 1 16 0 40
ASE_00092 0.68 0.49 0.96 55 63489 4 0 2 2 58
ASE_00099 0.82 0.68 0.98 82 64536 3 1 1 1 38
ASE_00104 0.80 0.69 0.93 82 64173 7 1 5 1 37
ASE_00105 0.61 0.43 0.87 48 64206 9 0 7 2 63
ASE_00107 0.78 0.72 0.84 91 73045 19 1 16 2 36
ASE_00115 0.68 0.50 0.93 51 54560 7 0 4 3 50
ASE_00118 0.52 0.27 1.00 28 60698 2 0 0 2 74
ASE_00119 0.34 0.13 0.88 14 62819 2 0 2 0 94
ASE_00123 0.64 0.46 0.89 39 38459 6 1 4 1 46
ASE_00126 0.75 0.68 0.82 56 40402 13 1 11 1 26
ASE_00128 0.72 0.56 0.93 56 53241 4 1 3 0 44
ASE_00129 0.74 0.64 0.87 71 62753 13 1 10 2 40
ASE_00131 0.63 0.45 0.88 38 39297 9 1 4 4 47
ASE_00134 0.74 0.61 0.91 58 50339 7 1 5 1 37
ASE_00135 0.64 0.46 0.89 50 63134 7 1 5 1 59
ASE_00136 0.75 0.61 0.92 56 48144 8 1 4 3 36
ASE_00137 0.80 0.68 0.93 67 48444 5 1 4 0 31
ASE_00138 0.80 0.65 0.98 53 40416 2 0 1 1 28
ASE_00140 0.66 0.47 0.92 59 70812 7 1 4 2 66
ASE_00142 0.80 0.70 0.92 85 67069 8 3 4 1 37
ASE_00146 0.68 0.54 0.86 67 70798 12 1 10 1 57
ASE_00153 0.54 0.48 0.60 35 57572 43 2 21 20 38
ASE_00163 0.72 0.54 0.96 50 53249 2 0 2 0 43
ASE_00165 0.67 0.50 0.89 51 52918 6 1 5 0 50
ASE_00170 0.70 0.55 0.89 51 48771 6 0 6 0 42
ASE_00171 0.72 0.57 0.92 54 48457 7 1 4 2 40
ASE_00172 0.69 0.49 0.98 52 58943 2 0 1 1 54
ASE_00174 0.66 0.47 0.94 51 61021 3 1 2 0 58
ASE_00175 0.53 0.42 0.66 45 59963 24 3 20 1 62
ASE_00179 0.71 0.52 0.96 44 44207 2 1 1 0 40
ASE_00180 0.70 0.53 0.91 53 51302 6 0 5 1 47
ASE_00181 0.71 0.54 0.95 57 57570 5 0 3 2 49
ASE_00182 0.55 0.35 0.86 48 84199 8 1 7 0 88
ASE_00183 0.67 0.47 0.96 53 61370 3 0 2 1 60
ASE_00184 0.69 0.58 0.83 59 54544 13 2 10 1 43
ASE_00185 0.62 0.41 0.95 52 73481 4 1 2 1 76
ASE_00190 0.46 0.23 0.91 21 45428 3 0 2 1 69
ASE_00197 0.74 0.64 0.86 93 89145 15 1 14 0 52
ASE_00198 0.80 0.68 0.96 69 52578 3 1 2 0 33
ASE_00203 0.82 0.70 0.96 67 46595 4 1 2 1 29
ASE_00212 0.75 0.65 0.86 96 93849 16 1 15 0 52
ASE_00214 0.69 0.59 0.80 61 56204 17 2 13 2 42
ASE_00215 0.62 0.40 0.95 40 48474 3 1 1 1 59
ASE_00216 0.82 0.71 0.95 58 39279 3 0 3 0 24
ASE_00217 0.67 0.56 0.82 50 40409 14 1 10 3 40
ASE_00221 0.75 0.61 0.93 71 64544 6 1 4 1 46
ASE_00228 0.79 0.69 0.92 59 46907 6 2 3 1 27
ASE_00229 0.79 0.69 0.90 60 42419 7 1 6 0 27
ASE_00231 0.76 0.63 0.92 60 47830 5 1 4 0 36
ASE_00232 0.85 0.75 0.95 63 38437 3 2 1 0 21
ASE_00234 0.61 0.42 0.90 54 75406 8 1 5 2 75
ASE_00238 0.57 0.37 0.89 42 64214 5 0 5 0 72
ASE_00241 0.73 0.64 0.84 56 43889 12 2 9 1 31
ASE_00242 0.81 0.71 0.93 79 60990 7 0 6 1 33
ASE_00254 0.84 0.74 0.95 61 36792 4 2 1 1 21
ASE_00257 0.82 0.68 0.99 66 50973 2 0 1 1 31
ASE_00263 0.69 0.48 0.98 58 70441 2 0 1 1 62
ASE_00267 0.72 0.66 0.79 58 45077 17 2 13 2 30
ASE_00270 0.52 0.27 1.00 35 72355 0 0 0 0 93
ASE_00274 0.66 0.47 0.92 48 55559 5 0 4 1 55
ASE_00277 0.64 0.56 0.74 51 48136 21 3 15 3 40
ASE_00279 0.72 0.58 0.89 59 53235 8 3 4 1 42
ASE_00280 0.75 0.58 0.97 57 51944 3 0 2 1 41
ASE_00281 0.81 0.68 0.97 60 44489 2 1 1 0 28
ASE_00282 0.60 0.40 0.89 51 77758 7 3 3 1 76
ASE_00283 0.71 0.56 0.91 60 61710 7 2 4 1 47
ASE_00284 0.68 0.51 0.90 55 58250 7 2 4 1 53
ASE_00285 0.63 0.44 0.89 54 68945 8 3 4 1 68
ASE_00286 0.75 0.59 0.95 54 46608 3 1 2 0 38
ASE_00287 0.66 0.49 0.91 50 54891 6 0 5 1 53
ASE_00292 0.55 0.43 0.71 59 81727 25 3 21 1 79
ASE_00294 0.75 0.60 0.94 103 114372 8 1 5 2 68
ASE_00296 0.71 0.53 0.96 77 91726 4 0 3 1 68
ASE_00297 0.68 0.47 0.98 46 52928 1 0 1 0 52
ASE_00298 0.62 0.39 1.00 44 67484 1 0 0 1 69
ASE_00328 0.80 0.66 0.97 74 72695 9 0 2 7 38
ASE_00332 0.80 0.71 0.89 98 81700 14 1 11 2 40
ASE_00340 0.63 0.48 0.84 41 46007 11 6 2 3 44
ASE_00342 0.82 0.75 0.90 86 62385 12 1 9 2 29
ASE_00353 0.79 0.69 0.91 74 57889 7 1 6 0 33
ASE_00361 0.65 0.43 0.96 55 75409 4 0 2 2 72
ASE_00362 0.80 0.69 0.93 63 48137 7 1 4 2 28
ASE_00363 0.75 0.64 0.88 60 51292 9 1 7 1 34
ASE_00364 0.79 0.67 0.93 70 54210 6 1 4 1 35
ASE_00366 0.68 0.49 0.94 48 58602 4 0 3 1 50
ASE_00367 0.78 0.70 0.87 60 43002 11 1 8 2 26
ASE_00369 0.79 0.64 0.97 68 55875 2 0 2 0 39
ASE_00370 0.78 0.67 0.90 56 41843 7 1 5 1 28
ASE_00372 0.70 0.54 0.90 54 51943 6 3 3 0 46
ASE_00374 0.77 0.64 0.93 56 44790 4 2 2 0 32
ASE_00376 0.65 0.51 0.83 54 56888 15 0 11 4 51
ASE_00377 0.75 0.62 0.92 66 57558 7 0 6 1 41
ASE_00379 0.75 0.63 0.90 56 45994 6 2 4 0 33
ASE_00382 0.78 0.69 0.89 58 41840 8 1 6 1 26
ASE_00383 0.79 0.66 0.95 69 54542 5 1 3 1 36
ASE_00384 0.78 0.68 0.90 63 48446 8 1 6 1 29
ASE_00386 0.70 0.56 0.87 54 50341 9 1 7 1 42
ASE_00387 0.63 0.45 0.87 47 55891 8 1 6 1 57
ASE_00388 0.78 0.69 0.90 61 45685 9 1 6 2 28
ASE_00390 0.81 0.72 0.91 61 42128 8 1 5 2 24
ASE_00393 0.70 0.57 0.87 53 47834 9 1 7 1 40
ASE_00394 0.72 0.62 0.83 58 46901 14 1 11 2 35
ASE_00395 0.78 0.71 0.86 60 41546 12 1 9 2 24
ASE_00396 0.78 0.71 0.86 59 41547 12 2 8 2 24
ASE_00397 0.80 0.69 0.92 72 54537 7 1 5 1 33
ASE_00398 0.68 0.53 0.87 55 55882 11 1 7 3 49
ASE_00400 0.67 0.45 0.98 48 57921 1 0 1 0 58
ASE_00401 0.60 0.37 0.98 47 76980 2 0 1 1 79
ASE_00402 0.79 0.68 0.91 58 42422 8 1 5 2 27
ASE_00403 0.75 0.63 0.91 67 55871 7 1 6 0 40
ASE_00404 0.81 0.69 0.94 59 43008 5 0 4 1 26
ASE_00406 0.73 0.62 0.85 58 48760 12 1 9 2 36
ASE_00411 0.64 0.44 0.93 39 49413 3 0 3 0 50
ASE_00412 0.62 0.40 0.98 42 58268 3 0 1 2 63
ASE_00413 0.72 0.54 0.96 44 44505 2 0 2 0 37
ASE_00415 0.55 0.34 0.90 35 54907 4 0 4 0 68
ASE_00416 0.58 0.36 0.92 46 77371 5 1 3 1 81
ASE_00419 0.67 0.48 0.94 49 54894 3 1 2 0 54
ASE_00422 0.72 0.55 0.95 52 46916 4 0 3 1 42
ASE_00423 0.76 0.59 0.98 64 56888 2 1 0 1 45
ASE_00428 0.60 0.39 0.91 49 76582 6 1 4 1 76
ASE_00430 0.77 0.61 0.98 59 46911 3 0 1 2 38
ASE_00437 0.55 0.47 0.66 63 79305 35 1 32 2 72
ASE_00441 0.63 0.44 0.91 49 64207 9 0 5 4 63
ASE_00448 0.75 0.63 0.88 71 64180 11 1 9 1 41
ASE_00451 0.77 0.72 0.83 90 70768 20 1 17 2 35
PDB_00571 0.87 0.80 0.95 20 3300 1 1 0 0 5
PDB_00828 0.84 0.70 1.00 19 2466 0 0 0 0 8
PDB_00829 0.84 0.71 1.00 17 2261 0 0 0 0 7
PDB_01020 0.86 0.74 1.00 17 2261 0 0 0 0 6
PDB_01073 0.84 0.71 1.00 24 4347 1 0 0 1 10
RFA_00599 0.65 0.46 0.91 51 101419 10 3 2 5 60
RFA_00601 0.86 0.82 0.91 93 99133 20 3 6 11 21
TMR_00017 0.72 0.55 0.93 56 67101 8 0 4 4 46
TMR_00018 0.71 0.60 0.85 55 64555 14 2 8 4 37
TMR_00038 0.67 0.49 0.92 54 71194 7 3 2 2 56
TMR_00042 0.74 0.64 0.85 63 62761 15 1 10 4 35
TMR_00046 0.64 0.53 0.77 51 62769 20 3 12 5 45
TMR_00048 0.73 0.63 0.85 60 64909 18 2 9 7 35
TMR_00080 0.60 0.36 0.97 35 70464 1 0 1 0 61
TMR_00082 0.65 0.44 0.95 42 67852 3 0 2 1 54
TMR_00123 0.69 0.55 0.86 56 66365 14 0 9 5 45
TMR_00137 0.47 0.28 0.78 25 61043 12 1 6 5 64
TMR_00142 0.61 0.55 0.68 56 70794 33 7 19 7 46
TMR_00207 0.76 0.60 0.95 62 72325 7 0 3 4 41
TMR_00257 0.71 0.54 0.93 53 67104 10 0 4 6 45
TMR_00271 0.54 0.35 0.82 32 64222 15 3 4 8 59
TMR_00366 0.65 0.57 0.74 57 67819 31 5 15 11 43
TMR_00378 0.63 0.53 0.76 51 67829 26 6 10 10 46
TMR_00399 0.45 0.31 0.66 29 64936 25 7 8 10 65
TMR_00404 0.66 0.57 0.76 52 67460 27 3 13 11 40
TMR_00427 0.73 0.59 0.90 57 67465 11 5 1 5 40
TMR_00443 0.69 0.55 0.86 57 67095 13 1 8 4 47
TMR_00451 0.54 0.36 0.80 32 63506 12 3 5 4 57
TMR_00458 0.61 0.41 0.90 38 63504 7 3 1 3 55
TMR_00469 0.79 0.70 0.90 70 64542 11 4 4 3 30
TMR_00472 0.77 0.66 0.89 64 64548 13 5 3 5 33
TMR_00519 0.61 0.46 0.80 44 63135 20 2 9 9 51
TMR_00520 0.60 0.47 0.76 47 63128 24 3 12 9 52
TMR_00522 0.65 0.47 0.88 46 63138 14 2 4 8 51
TMR_00528 0.60 0.46 0.78 45 63132 22 4 9 9 52
TMR_00568 0.69 0.54 0.88 53 60666 15 0 7 8 46
TMR_00571 0.66 0.49 0.89 49 60671 14 1 5 8 50
TMR_00580 0.65 0.49 0.88 49 60670 14 1 6 7 51
TMR_00584 0.72 0.57 0.92 55 61015 13 1 4 8 42
TMR_00586 0.70 0.56 0.89 54 61014 14 1 6 7 43
TMR_00616 0.76 0.63 0.91 62 67093 11 0 6 5 37
TMR_00699 0.76 0.63 0.91 64 67091 11 1 5 5 38
TMR_00702 0.77 0.65 0.90 65 67089 12 1 6 5 35

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Performance of Multilign(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 11862
Total TN 11495758
Total FP 5464
Total FP CONTRA 615
Total FP INCONS 4034
Total FP COMP 815
Total FN 8223
Total Scores
MCC 0.651
Average MCC ± 95% Confidence Intervals 0.656 ± 0.017
Sensitivity 0.591
Positive Predictive Value 0.718
Nr of predictions 196

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2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00005 0.73 0.66 0.82 77 57876 23 0 17 6 40
ASE_00006 0.78 0.76 0.81 71 47498 22 1 16 5 22
ASE_00007 0.70 0.63 0.78 69 59596 25 0 20 5 41
ASE_00012 0.62 0.56 0.69 69 73820 36 3 28 5 54
ASE_00018 0.75 0.67 0.84 90 80494 19 1 16 2 44
ASE_00020 0.49 0.43 0.56 54 73823 43 4 39 0 72
ASE_00021 0.62 0.51 0.75 82 104086 30 5 23 2 78
ASE_00035 0.62 0.57 0.68 67 70402 35 3 28 4 51
ASE_00037 0.56 0.49 0.64 54 59255 31 4 27 0 56
ASE_00038 0.57 0.53 0.61 54 53540 37 3 31 3 47
ASE_00040 0.69 0.62 0.75 83 78893 28 0 27 1 50
ASE_00041 0.72 0.67 0.78 72 57538 21 1 19 1 36
ASE_00042 0.50 0.41 0.61 60 90002 41 2 36 3 85
ASE_00044 0.83 0.77 0.89 81 54524 12 0 10 2 24
ASE_00064 0.76 0.67 0.86 60 45381 21 0 10 11 29
ASE_00068 0.76 0.71 0.82 60 37602 17 0 13 4 25
ASE_00074 0.82 0.78 0.87 93 67789 14 1 13 0 26
ASE_00075 0.75 0.64 0.87 104 108691 24 3 13 8 58
ASE_00077 0.61 0.55 0.67 47 45080 33 5 18 10 39
ASE_00078 0.81 0.77 0.84 64 42995 18 0 12 6 19
ASE_00080 0.52 0.48 0.57 59 71528 44 5 39 0 64
ASE_00081 0.80 0.75 0.86 73 49685 13 0 12 1 24
ASE_00082 0.58 0.53 0.63 62 70402 47 3 33 11 54
ASE_00083 0.82 0.74 0.91 81 62392 10 0 8 2 29
ASE_00084 0.60 0.55 0.67 54 53547 27 1 26 0 45
ASE_00087 0.47 0.40 0.57 57 88310 43 2 41 0 87
ASE_00090 0.52 0.46 0.60 46 55534 36 5 26 5 55
ASE_00092 0.69 0.63 0.76 71 63452 24 0 23 1 42
ASE_00099 0.81 0.76 0.86 91 64514 16 2 13 1 29
ASE_00104 0.82 0.76 0.89 90 64160 16 1 10 5 29
ASE_00105 0.53 0.49 0.58 54 64168 41 6 33 2 57
ASE_00107 0.64 0.57 0.73 72 73055 28 1 25 2 55
ASE_00115 0.72 0.61 0.84 62 54541 12 1 11 0 39
ASE_00118 0.55 0.49 0.62 50 60645 33 1 30 2 52
ASE_00119 0.55 0.50 0.61 54 62747 36 1 33 2 54
ASE_00123 0.55 0.51 0.60 43 38431 33 1 28 4 42
ASE_00126 0.70 0.70 0.71 57 40390 30 3 20 7 25
ASE_00128 0.74 0.62 0.87 62 53230 13 1 8 4 38
ASE_00129 0.69 0.63 0.75 70 62742 23 2 21 0 41
ASE_00131 0.48 0.42 0.54 36 39273 36 2 29 5 49
ASE_00134 0.71 0.67 0.74 64 50317 23 3 19 1 31
ASE_00135 0.54 0.49 0.60 53 63102 40 6 29 5 56
ASE_00136 0.83 0.78 0.89 72 48124 16 0 9 7 20
ASE_00137 0.52 0.48 0.56 47 48432 42 0 37 5 51
ASE_00138 0.79 0.73 0.87 59 40402 12 3 6 3 22
ASE_00140 0.46 0.38 0.55 48 70789 40 3 36 1 77
ASE_00142 0.72 0.67 0.78 82 67056 25 3 20 2 40
ASE_00146 0.64 0.54 0.76 67 70788 22 1 20 1 57
ASE_00153 0.38 0.37 0.39 27 57560 76 9 34 33 46
ASE_00163 0.69 0.67 0.71 62 53214 27 7 18 2 31
ASE_00165 0.54 0.49 0.60 49 52893 35 6 27 2 52
ASE_00170 0.83 0.77 0.90 72 48748 10 2 6 2 21
ASE_00171 0.88 0.80 0.96 75 48438 8 0 3 5 19
ASE_00172 0.66 0.58 0.76 61 58916 25 3 16 6 45
ASE_00174 0.53 0.45 0.63 49 60997 32 1 28 3 60
ASE_00175 0.63 0.55 0.73 59 59950 27 2 20 5 48
ASE_00179 0.76 0.69 0.84 58 44184 15 1 10 4 26
ASE_00180 0.77 0.70 0.85 70 51278 15 3 9 3 30
ASE_00181 0.67 0.63 0.71 67 57536 30 0 27 3 39
ASE_00182 0.48 0.40 0.57 55 84158 42 2 40 0 81
ASE_00183 0.70 0.63 0.77 71 61333 23 0 21 2 42
ASE_00184 0.76 0.68 0.85 69 54534 20 0 12 8 33
ASE_00185 0.42 0.38 0.47 48 73434 58 2 52 4 80
ASE_00190 0.46 0.37 0.57 33 45393 28 4 21 3 57
ASE_00197 0.42 0.36 0.50 52 89150 54 1 50 3 93
ASE_00198 0.63 0.58 0.69 59 52564 30 3 24 3 43
ASE_00203 0.56 0.52 0.61 50 46583 36 0 32 4 46
ASE_00212 0.66 0.59 0.74 88 93842 33 1 30 2 60
ASE_00214 0.83 0.79 0.87 81 56187 17 3 9 5 22
ASE_00215 0.18 0.15 0.23 15 48450 55 4 47 4 84
ASE_00216 0.71 0.67 0.74 55 39266 26 2 17 7 27
ASE_00217 0.50 0.46 0.55 41 40395 39 1 33 5 49
ASE_00221 0.65 0.56 0.74 66 64531 24 0 23 1 51
ASE_00228 0.69 0.67 0.72 58 46890 26 4 19 3 28
ASE_00229 0.60 0.57 0.63 50 42406 32 4 26 2 37
ASE_00231 0.44 0.40 0.50 38 47819 42 3 35 4 58
ASE_00232 0.81 0.81 0.81 68 38419 17 6 10 1 16
ASE_00234 0.68 0.60 0.76 78 75363 27 6 19 2 51
ASE_00238 0.50 0.45 0.55 51 64169 42 6 35 1 63
ASE_00241 0.78 0.71 0.86 62 43884 15 1 9 5 25
ASE_00242 0.72 0.66 0.80 74 60982 24 1 18 5 38
ASE_00254 0.48 0.46 0.50 38 36780 39 5 33 1 44
ASE_00257 0.70 0.64 0.78 62 50960 25 1 17 7 35
ASE_00263 0.46 0.41 0.52 49 70405 47 6 40 1 71
ASE_00267 0.75 0.68 0.82 60 45077 21 1 12 8 28
ASE_00270 0.56 0.49 0.64 63 72292 38 2 33 3 65
ASE_00274 0.59 0.51 0.67 53 55532 28 5 21 2 50
ASE_00277 0.79 0.75 0.83 68 48123 16 0 14 2 23
ASE_00279 0.78 0.73 0.82 74 53211 20 2 14 4 27
ASE_00280 0.72 0.66 0.78 65 51920 21 1 17 3 33
ASE_00281 0.80 0.73 0.89 64 44479 15 1 7 7 24
ASE_00282 0.48 0.42 0.56 53 77721 42 3 38 1 74
ASE_00283 0.73 0.67 0.80 72 61686 23 0 18 5 35
ASE_00284 0.65 0.59 0.71 64 58221 29 3 23 3 44
ASE_00285 0.58 0.51 0.67 62 68914 32 3 27 2 60
ASE_00286 0.82 0.74 0.91 68 46590 10 1 6 3 24
ASE_00287 0.62 0.56 0.68 58 54861 28 0 27 1 45
ASE_00292 0.74 0.64 0.84 89 81704 22 2 15 5 49
ASE_00294 0.75 0.63 0.89 108 114359 16 1 13 2 63
ASE_00296 0.64 0.54 0.76 78 91704 26 1 23 2 67
ASE_00297 0.62 0.53 0.72 52 52903 21 1 19 1 46
ASE_00298 0.48 0.43 0.53 49 67435 46 2 42 2 64
ASE_00328 0.76 0.67 0.87 75 72685 23 1 10 12 37
ASE_00332 0.45 0.37 0.55 51 81717 44 3 39 2 87
ASE_00340 0.58 0.54 0.63 46 45983 31 8 19 4 39
ASE_00342 0.82 0.76 0.88 87 62382 12 2 10 0 28
ASE_00353 0.65 0.62 0.69 66 57874 35 2 28 5 41
ASE_00361 0.58 0.49 0.69 62 75376 29 3 25 1 65
ASE_00362 0.74 0.65 0.86 59 48136 10 0 10 0 32
ASE_00363 0.81 0.73 0.90 69 51283 14 1 7 6 25
ASE_00364 0.63 0.56 0.71 59 54202 29 1 23 5 46
ASE_00366 0.62 0.57 0.67 56 58570 31 6 21 4 42
ASE_00367 0.57 0.53 0.61 46 42995 36 1 29 6 40
ASE_00369 0.82 0.74 0.92 79 55859 7 1 6 0 28
ASE_00370 0.86 0.81 0.92 68 41831 14 0 6 8 16
ASE_00372 0.67 0.59 0.77 59 51926 19 1 17 1 41
ASE_00374 0.81 0.73 0.90 64 44779 8 1 6 1 24
ASE_00376 0.66 0.61 0.71 64 56863 28 1 25 2 41
ASE_00377 0.61 0.55 0.69 59 57544 29 3 24 2 48
ASE_00379 0.54 0.48 0.61 43 45986 38 0 27 11 46
ASE_00382 0.86 0.81 0.92 68 41831 14 0 6 8 16
ASE_00383 0.79 0.72 0.85 76 54526 14 4 9 1 29
ASE_00384 0.70 0.65 0.75 60 48436 26 4 16 6 32
ASE_00386 0.65 0.60 0.70 58 50320 27 5 20 2 38
ASE_00387 0.67 0.63 0.70 66 55851 29 0 28 1 38
ASE_00388 0.51 0.47 0.56 42 45678 40 2 31 7 47
ASE_00390 0.85 0.80 0.89 68 42119 17 0 8 9 17
ASE_00393 0.70 0.63 0.77 59 47818 20 1 17 2 34
ASE_00394 0.80 0.72 0.88 67 46895 13 4 5 4 26
ASE_00395 0.73 0.69 0.77 58 41541 21 0 17 4 26
ASE_00396 0.72 0.66 0.79 55 41546 19 2 13 4 28
ASE_00397 0.74 0.69 0.79 72 54524 23 1 18 4 33
ASE_00398 0.68 0.62 0.76 64 55861 29 1 19 9 40
ASE_00400 0.74 0.69 0.80 73 57879 19 1 17 1 33
ASE_00401 0.52 0.44 0.63 55 76940 40 0 33 7 71
ASE_00402 0.76 0.69 0.84 59 42416 15 1 10 4 26
ASE_00403 0.66 0.58 0.76 62 55863 25 3 17 5 45
ASE_00404 0.78 0.73 0.83 62 42996 17 1 12 4 23
ASE_00406 0.82 0.73 0.91 69 48752 15 0 7 8 25
ASE_00411 0.57 0.53 0.62 47 49379 30 10 19 1 42
ASE_00412 0.56 0.50 0.62 53 58226 34 3 29 2 52
ASE_00413 0.60 0.57 0.64 46 44479 27 2 24 1 35
ASE_00415 0.60 0.57 0.63 59 54853 40 2 32 6 44
ASE_00416 0.69 0.59 0.80 75 77327 28 1 18 9 52
ASE_00419 0.75 0.68 0.83 70 54862 16 3 11 2 33
ASE_00422 0.65 0.63 0.67 59 46883 30 4 25 1 35
ASE_00423 0.84 0.77 0.92 84 56862 10 1 6 3 25
ASE_00428 0.57 0.54 0.60 68 76522 47 4 42 1 57
ASE_00430 0.79 0.76 0.82 74 46881 16 2 14 0 23
ASE_00437 0.67 0.60 0.75 81 79293 27 1 26 0 54
ASE_00441 0.66 0.57 0.77 64 64178 19 2 17 0 48
ASE_00448 0.63 0.59 0.67 66 64163 39 2 30 7 46
ASE_00451 0.68 0.60 0.77 75 70779 24 1 21 2 50
PDB_00571 0.85 0.76 0.95 19 3301 1 1 0 0 6
PDB_00828 0.88 0.78 1.00 21 2464 0 0 0 0 6
PDB_00829 0.86 0.75 1.00 18 2260 2 0 0 2 6
PDB_01020 0.86 0.74 1.00 17 2261 3 0 0 3 6
PDB_01073 0.86 0.74 1.00 25 4346 1 0 0 1 9
RFA_00599 0.71 0.71 0.71 79 101363 50 13 20 17 32
RFA_00601 0.58 0.54 0.61 62 99134 50 10 29 11 52
TMR_00017 0.59 0.56 0.62 57 67069 39 8 27 4 45
TMR_00018 0.59 0.54 0.65 50 64543 31 7 20 4 42
TMR_00038 0.73 0.66 0.79 73 71161 24 1 18 5 37
TMR_00042 0.61 0.57 0.65 56 62749 34 7 23 4 42
TMR_00046 0.65 0.63 0.67 60 62746 35 9 20 6 36
TMR_00048 0.59 0.55 0.63 52 64898 38 6 24 8 43
TMR_00080 0.51 0.46 0.56 44 70422 34 10 24 0 52
TMR_00082 0.65 0.59 0.71 57 67816 30 7 16 7 39
TMR_00123 0.64 0.59 0.68 60 66342 34 4 24 6 41
TMR_00137 0.33 0.28 0.38 25 61009 44 9 32 3 64
TMR_00142 0.62 0.64 0.61 65 70769 49 12 30 7 37
TMR_00207 0.40 0.35 0.45 36 72310 49 6 38 5 67
TMR_00257 0.68 0.61 0.76 60 67082 27 4 15 8 38
TMR_00271 0.64 0.56 0.74 51 64192 20 6 12 2 40
TMR_00366 0.64 0.60 0.67 60 67807 40 12 17 11 40
TMR_00378 0.67 0.63 0.71 61 67810 38 5 20 13 36
TMR_00399 0.48 0.45 0.52 42 64899 46 9 30 7 52
TMR_00404 0.59 0.59 0.60 54 67438 49 12 24 13 38
TMR_00427 0.53 0.41 0.69 40 67470 22 7 11 4 57
TMR_00443 0.67 0.59 0.77 61 67082 22 4 14 4 43
TMR_00451 0.52 0.45 0.60 40 63479 31 7 20 4 49
TMR_00458 0.70 0.63 0.77 59 63469 21 4 14 3 34
TMR_00469 0.75 0.73 0.78 73 64526 30 7 14 9 27
TMR_00472 0.76 0.73 0.80 71 64531 23 7 11 5 26
TMR_00519 0.60 0.57 0.64 54 63106 34 12 18 4 41
TMR_00520 0.67 0.62 0.73 61 63106 31 4 19 8 38
TMR_00522 0.53 0.47 0.60 46 63113 36 9 22 5 51
TMR_00528 0.51 0.45 0.58 44 63114 37 10 22 5 53
TMR_00568 0.62 0.59 0.65 58 60637 40 8 23 9 41
TMR_00571 0.69 0.65 0.73 64 60638 34 10 14 10 35
TMR_00580 0.62 0.61 0.63 61 60629 46 10 26 10 39
TMR_00584 0.65 0.61 0.69 59 60989 36 6 21 9 38
TMR_00586 0.60 0.59 0.61 57 60982 43 11 25 7 40
TMR_00616 0.65 0.63 0.68 62 67070 35 7 22 6 37
TMR_00699 0.69 0.60 0.80 61 67085 16 2 13 1 41
TMR_00702 0.63 0.54 0.73 54 67087 26 7 13 6 46

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.