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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of IPknot - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for IPknot & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric IPknot CMfinder(20)
MCC 0.649 > 0.482
Average MCC ± 95% Confidence Intervals 0.652 ± 0.017 > 0.484 ± 0.018
Sensitivity 0.575 > 0.310
Positive Predictive Value 0.734 < 0.749
Total TP 12391 > 6683
Total TN 12431869 < 12439819
Total FP 5145 > 2540
Total FP CONTRA 689 > 195
Total FP INCONS 3790 > 2042
Total FP COMP 666 > 303
Total FN 9157 < 14865
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of IPknot and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for IPknot and CMfinder(20)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for IPknot and CMfinder(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for IPknot and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for IPknot and CMfinder(20)).

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Performance of IPknot - scored higher in this pairwise comparison

1. Total counts & total scores for IPknot

Total Base Pair Counts
Total TP 12391
Total TN 12431869
Total FP 5145
Total FP CONTRA 689
Total FP INCONS 3790
Total FP COMP 666
Total FN 9157
Total Scores
MCC 0.649
Average MCC ± 95% Confidence Intervals 0.652 ± 0.017
Sensitivity 0.575
Positive Predictive Value 0.734
Nr of predictions 209

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2. Individual counts for IPknot [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.75 0.66 0.85 64 47820 11 5 6 0 33
ASE_00005 0.59 0.51 0.69 60 57883 30 0 27 3 57
ASE_00006 0.60 0.52 0.70 48 47517 22 3 18 1 45
ASE_00007 0.63 0.55 0.72 60 59602 27 0 23 4 50
ASE_00012 0.66 0.56 0.78 69 73832 22 5 14 3 54
ASE_00018 0.70 0.64 0.77 86 80489 27 0 26 1 48
ASE_00020 0.67 0.58 0.77 73 73825 22 2 20 0 53
ASE_00021 0.70 0.57 0.85 91 104089 21 3 13 5 69
ASE_00022 0.69 0.52 0.93 64 82959 9 0 5 4 60
ASE_00028 0.70 0.60 0.81 76 84572 24 3 15 6 50
ASE_00035 0.44 0.30 0.66 35 70447 21 4 14 3 83
ASE_00037 0.47 0.39 0.57 43 59265 34 0 32 2 67
ASE_00038 0.59 0.53 0.66 54 53546 28 4 24 0 47
ASE_00040 0.51 0.42 0.62 56 78913 38 0 34 4 77
ASE_00041 0.69 0.50 0.96 54 57574 4 0 2 2 54
ASE_00042 0.60 0.51 0.70 74 89994 33 1 31 1 71
ASE_00044 0.70 0.70 0.72 73 54513 34 3 26 5 32
ASE_00064 0.68 0.60 0.77 53 45382 22 3 13 6 36
ASE_00068 0.75 0.60 0.94 51 37621 3 0 3 0 34
ASE_00074 0.49 0.45 0.54 53 67798 45 4 41 0 66
ASE_00075 0.71 0.61 0.83 99 108691 25 2 19 4 63
ASE_00077 0.68 0.53 0.87 46 45097 12 2 5 5 40
ASE_00078 0.70 0.57 0.87 47 43017 7 1 6 0 36
ASE_00080 0.41 0.36 0.47 44 71537 54 5 45 4 79
ASE_00081 0.79 0.71 0.88 69 49692 10 1 8 1 28
ASE_00082 0.83 0.74 0.93 86 70408 18 0 6 12 30
ASE_00083 0.77 0.72 0.82 79 62385 22 0 17 5 31
ASE_00084 0.83 0.74 0.94 73 53550 8 1 4 3 26
ASE_00087 0.74 0.63 0.87 90 88306 14 2 12 0 54
ASE_00090 0.66 0.58 0.75 59 55532 20 1 19 0 42
ASE_00092 0.85 0.78 0.93 88 63451 9 1 6 2 25
ASE_00099 0.80 0.70 0.92 84 64529 7 0 7 0 36
ASE_00104 0.75 0.66 0.84 79 64167 15 2 13 0 40
ASE_00105 0.48 0.41 0.56 46 64179 39 6 30 3 65
ASE_00107 0.73 0.66 0.82 84 73050 19 1 18 0 43
ASE_00115 0.74 0.68 0.81 69 54530 23 4 12 7 32
ASE_00118 0.40 0.37 0.44 38 60639 50 3 46 1 64
ASE_00119 0.85 0.81 0.91 87 62739 9 1 8 0 21
ASE_00123 0.52 0.49 0.55 42 38427 38 2 32 4 43
ASE_00125 0.75 0.65 0.86 57 39274 11 0 9 2 31
ASE_00126 0.65 0.59 0.72 48 40403 25 1 18 6 34
ASE_00128 0.78 0.65 0.94 65 53232 7 0 4 3 35
ASE_00129 0.70 0.67 0.74 74 62735 27 5 21 1 37
ASE_00131 0.80 0.66 0.98 56 39283 5 0 1 4 29
ASE_00134 0.51 0.47 0.55 45 50321 37 4 33 0 50
ASE_00135 0.67 0.58 0.79 63 63110 22 1 16 5 46
ASE_00136 0.61 0.52 0.72 48 48138 28 1 18 9 44
ASE_00137 0.75 0.68 0.82 67 48434 15 0 15 0 31
ASE_00138 0.58 0.48 0.70 39 40414 17 1 16 0 42
ASE_00140 0.72 0.61 0.85 76 70787 14 3 10 1 49
ASE_00142 0.73 0.65 0.81 79 67064 19 4 14 1 43
ASE_00146 0.55 0.43 0.72 53 70802 22 5 16 1 71
ASE_00153 0.52 0.51 0.54 37 57562 60 6 25 29 36
ASE_00163 0.39 0.35 0.43 33 53224 53 4 40 9 60
ASE_00165 0.65 0.55 0.77 56 52902 18 4 13 1 45
ASE_00170 0.63 0.55 0.73 51 48758 20 3 16 1 42
ASE_00171 0.71 0.67 0.76 63 48433 20 4 16 0 31
ASE_00172 0.81 0.71 0.94 75 58916 5 1 4 0 31
ASE_00174 0.63 0.60 0.66 65 60977 33 8 25 0 44
ASE_00175 0.62 0.55 0.70 59 59947 26 2 23 1 48
ASE_00179 0.65 0.56 0.75 47 44190 18 2 14 2 37
ASE_00180 0.69 0.56 0.85 56 51294 10 2 8 0 44
ASE_00181 0.60 0.53 0.67 56 57547 31 0 27 4 50
ASE_00182 0.57 0.53 0.62 72 84139 44 3 41 0 64
ASE_00183 0.74 0.68 0.81 77 61330 18 0 18 0 36
ASE_00184 0.71 0.70 0.73 71 54518 26 4 22 0 31
ASE_00185 0.79 0.69 0.92 88 73440 10 0 8 2 40
ASE_00186 0.74 0.68 0.81 90 78892 26 1 20 5 42
ASE_00190 0.75 0.58 0.98 52 45398 3 0 1 2 38
ASE_00197 0.67 0.57 0.78 83 89147 28 1 22 5 62
ASE_00198 0.72 0.63 0.83 64 52573 13 2 11 0 38
ASE_00203 0.77 0.69 0.87 66 46589 10 1 9 0 30
ASE_00212 0.73 0.68 0.79 101 93833 31 3 24 4 47
ASE_00214 0.80 0.78 0.83 80 56184 23 3 13 7 23
ASE_00215 0.48 0.41 0.56 41 48443 32 1 31 0 58
ASE_00216 0.66 0.62 0.70 51 39267 22 3 19 0 31
ASE_00217 0.34 0.29 0.41 26 40406 39 7 31 1 64
ASE_00221 0.61 0.46 0.82 54 64554 12 1 11 0 63
ASE_00228 0.78 0.74 0.82 64 46893 16 6 8 2 22
ASE_00229 0.73 0.63 0.83 55 42420 12 3 8 1 32
ASE_00231 0.74 0.66 0.83 63 47819 13 3 10 0 33
ASE_00232 0.80 0.77 0.82 65 38424 14 7 7 0 19
ASE_00234 0.58 0.49 0.70 63 75376 31 2 25 4 66
ASE_00238 0.64 0.54 0.75 62 64178 22 1 20 1 52
ASE_00241 0.72 0.60 0.87 52 43896 8 1 7 0 35
ASE_00242 0.73 0.59 0.92 66 61003 6 1 5 0 46
ASE_00248 0.71 0.61 0.84 69 62399 15 0 13 2 45
ASE_00254 0.76 0.68 0.85 56 36790 15 3 7 5 26
ASE_00255 0.72 0.62 0.85 80 74597 14 3 11 0 50
ASE_00257 0.76 0.63 0.91 61 50973 6 1 5 0 36
ASE_00263 0.70 0.62 0.80 74 70407 19 3 16 0 46
ASE_00267 0.54 0.42 0.70 37 45097 22 0 16 6 51
ASE_00270 0.76 0.73 0.79 93 72273 26 1 23 2 35
ASE_00274 0.64 0.55 0.75 57 55535 19 5 14 0 46
ASE_00277 0.59 0.53 0.66 48 48132 25 4 21 0 43
ASE_00279 0.73 0.62 0.86 63 53228 10 3 7 0 38
ASE_00280 0.70 0.61 0.81 60 51929 15 1 13 1 38
ASE_00281 0.82 0.74 0.90 65 44479 13 0 7 6 23
ASE_00282 0.55 0.51 0.60 65 77706 44 6 38 0 62
ASE_00283 0.77 0.72 0.83 77 61683 16 5 11 0 30
ASE_00284 0.69 0.68 0.72 73 58209 34 5 24 5 35
ASE_00285 0.80 0.75 0.86 91 68900 23 3 12 8 31
ASE_00286 0.67 0.57 0.80 52 46600 17 1 12 4 40
ASE_00287 0.72 0.69 0.76 71 54853 23 2 20 1 32
ASE_00292 0.68 0.60 0.76 83 81701 27 2 24 1 55
ASE_00294 0.78 0.68 0.90 117 114351 14 1 12 1 54
ASE_00296 0.48 0.43 0.53 63 91688 56 5 50 1 82
ASE_00297 0.68 0.62 0.74 61 52893 21 3 18 0 37
ASE_00298 0.57 0.51 0.64 58 67438 34 1 31 2 55
ASE_00318 0.52 0.43 0.64 51 80120 32 4 25 3 67
ASE_00328 0.70 0.60 0.83 67 72690 20 4 10 6 45
ASE_00332 0.55 0.50 0.60 69 81695 47 2 44 1 69
ASE_00335 0.68 0.59 0.78 68 75379 25 2 17 6 48
ASE_00340 0.76 0.75 0.77 64 45973 25 8 11 6 21
ASE_00342 0.75 0.68 0.83 78 62387 17 1 15 1 37
ASE_00353 0.57 0.51 0.63 55 57882 35 4 29 2 52
ASE_00361 0.53 0.47 0.59 60 75364 45 9 33 3 67
ASE_00362 0.66 0.59 0.74 54 48132 20 2 17 1 37
ASE_00363 0.76 0.64 0.91 60 51294 7 0 6 1 34
ASE_00364 0.63 0.56 0.70 59 54201 25 3 22 0 46
ASE_00366 0.54 0.51 0.58 50 58567 36 5 31 0 48
ASE_00367 0.62 0.55 0.71 47 43005 23 5 14 4 39
ASE_00369 0.73 0.71 0.75 76 55843 27 0 26 1 31
ASE_00370 0.49 0.43 0.55 36 41840 29 1 28 0 48
ASE_00372 0.74 0.68 0.80 68 51918 20 3 14 3 32
ASE_00374 0.64 0.61 0.68 54 44770 26 5 21 0 34
ASE_00376 0.62 0.57 0.68 60 56865 30 5 23 2 45
ASE_00377 0.77 0.74 0.81 79 57532 24 3 16 5 28
ASE_00379 0.70 0.62 0.79 55 45986 16 5 10 1 34
ASE_00382 0.69 0.58 0.82 49 41845 14 5 6 3 35
ASE_00383 0.71 0.64 0.80 67 54531 19 5 12 2 38
ASE_00384 0.73 0.71 0.76 65 48430 25 1 20 4 27
ASE_00386 0.65 0.60 0.70 58 50320 30 1 24 5 38
ASE_00387 0.75 0.65 0.86 68 55866 13 1 10 2 36
ASE_00388 0.74 0.61 0.90 54 45693 7 0 6 1 35
ASE_00390 0.77 0.71 0.85 60 42124 18 0 11 7 25
ASE_00393 0.72 0.65 0.81 60 47821 15 0 14 1 33
ASE_00394 0.80 0.76 0.85 71 46887 14 3 10 1 22
ASE_00395 0.77 0.73 0.81 61 41541 14 2 12 0 23
ASE_00396 0.68 0.61 0.76 51 41549 18 5 11 2 32
ASE_00397 0.81 0.72 0.92 76 54532 7 2 5 0 29
ASE_00398 0.65 0.59 0.72 61 55860 25 1 23 1 43
ASE_00400 0.74 0.65 0.83 69 57887 15 1 13 1 37
ASE_00401 0.64 0.60 0.68 75 76918 35 5 30 0 51
ASE_00402 0.68 0.60 0.77 51 42420 15 4 11 0 34
ASE_00403 0.57 0.47 0.69 50 55873 22 0 22 0 57
ASE_00404 0.58 0.51 0.66 43 43006 22 1 21 0 42
ASE_00406 0.74 0.64 0.87 60 48759 11 0 9 2 34
ASE_00411 0.59 0.46 0.75 41 49400 15 5 9 1 48
ASE_00412 0.56 0.47 0.67 49 58238 24 7 17 0 56
ASE_00413 0.47 0.46 0.49 37 44475 42 5 34 3 44
ASE_00415 0.70 0.65 0.74 67 54856 28 1 22 5 36
ASE_00416 0.71 0.60 0.84 76 77330 20 0 15 5 51
ASE_00419 0.78 0.74 0.83 76 54854 17 3 13 1 27
ASE_00422 0.69 0.65 0.74 61 46889 26 6 15 5 33
ASE_00423 0.65 0.64 0.66 70 56847 36 6 30 0 39
ASE_00428 0.65 0.59 0.72 74 76533 33 2 27 4 51
ASE_00430 0.76 0.68 0.85 66 46893 17 3 9 5 31
ASE_00437 0.55 0.41 0.74 56 79325 20 0 20 0 79
ASE_00441 0.79 0.72 0.86 81 64167 15 2 11 2 31
ASE_00448 0.53 0.42 0.66 47 64190 30 4 20 6 65
ASE_00451 0.75 0.66 0.85 82 70780 14 2 12 0 43
PDB_00571 0.79 0.76 0.83 19 3298 4 2 2 0 6
PDB_00828 0.90 0.81 1.00 22 2463 0 0 0 0 5
PDB_00829 0.86 0.75 1.00 18 2260 0 0 0 0 6
PDB_01020 0.86 0.74 1.00 17 2261 1 0 0 1 6
PDB_01073 0.80 0.65 1.00 22 4349 1 0 0 1 12
RFA_00599 0.75 0.73 0.77 81 101370 40 8 16 16 30
RFA_00601 0.45 0.46 0.43 53 99113 82 25 44 13 61
RFA_00602 0.42 0.43 0.40 50 101351 83 20 54 9 66
TMR_00017 0.70 0.55 0.89 56 67098 11 0 7 4 46
TMR_00018 0.40 0.33 0.48 30 64558 36 6 26 4 62
TMR_00038 0.23 0.21 0.25 23 71161 75 9 60 6 87
TMR_00042 0.38 0.34 0.44 33 62760 45 2 40 3 65
TMR_00046 0.50 0.48 0.53 46 62748 45 5 36 4 50
TMR_00048 0.49 0.48 0.50 46 64888 54 6 40 8 49
TMR_00080 0.65 0.60 0.70 58 70417 26 6 19 1 38
TMR_00082 0.78 0.77 0.80 74 67803 24 8 11 5 22
TMR_00123 0.85 0.77 0.93 78 66346 11 0 6 5 23
TMR_00137 0.34 0.28 0.40 25 61013 45 6 31 8 64
TMR_00142 0.65 0.63 0.67 64 70780 39 9 23 7 38
TMR_00207 0.47 0.40 0.56 41 72317 36 3 29 4 62
TMR_00257 0.63 0.50 0.80 49 67100 18 2 10 6 49
TMR_00271 0.62 0.56 0.68 51 64186 35 6 18 11 40
TMR_00332 0.61 0.46 0.81 46 67104 16 0 11 5 53
TMR_00366 0.63 0.53 0.76 53 67826 28 5 12 11 47
TMR_00378 0.32 0.28 0.38 27 67824 56 14 31 11 70
TMR_00399 0.41 0.33 0.51 31 64919 37 11 19 7 63
TMR_00404 0.60 0.55 0.65 51 67450 38 6 21 11 41
TMR_00427 0.60 0.52 0.69 50 67456 27 10 12 5 47
TMR_00443 0.65 0.55 0.77 57 67087 24 8 9 7 47
TMR_00451 0.26 0.26 0.27 23 63461 66 16 46 4 66
TMR_00458 0.48 0.40 0.59 37 63483 33 6 20 7 56
TMR_00469 0.52 0.51 0.54 51 64525 48 16 28 4 49
TMR_00472 0.55 0.44 0.67 43 64556 26 6 15 5 54
TMR_00519 0.44 0.35 0.57 33 63132 35 7 18 10 62
TMR_00520 0.52 0.46 0.58 46 63110 43 7 27 9 53
TMR_00522 0.53 0.47 0.60 46 63113 39 5 26 8 51
TMR_00528 0.43 0.40 0.46 39 63106 55 11 34 10 58
TMR_00540 0.70 0.63 0.79 65 73454 27 6 11 10 39
TMR_00568 0.66 0.53 0.84 52 60664 16 0 10 6 47
TMR_00571 0.68 0.60 0.79 59 60651 24 2 14 8 40
TMR_00580 0.74 0.71 0.77 71 60634 29 2 19 8 29
TMR_00584 0.61 0.59 0.64 57 60986 36 3 29 4 40
TMR_00586 0.58 0.53 0.65 51 60996 34 6 22 6 46
TMR_00616 0.53 0.45 0.62 45 67088 33 6 22 5 54
TMR_00699 0.80 0.72 0.89 73 67079 13 3 6 4 29
TMR_00702 0.58 0.48 0.70 48 67092 26 5 16 5 52
TMR_00703 0.53 0.45 0.61 45 67454 34 3 26 5 54

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 6683
Total TN 12439819
Total FP 2540
Total FP CONTRA 195
Total FP INCONS 2042
Total FP COMP 303
Total FN 14865
Total Scores
MCC 0.482
Average MCC ± 95% Confidence Intervals 0.484 ± 0.018
Sensitivity 0.310
Positive Predictive Value 0.749
Nr of predictions 209

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.50 0.29 0.88 28 47863 4 0 4 0 69
ASE_00005 0.41 0.26 0.67 30 57925 15 0 15 0 87
ASE_00006 0.54 0.40 0.74 37 47536 13 1 12 0 56
ASE_00007 0.64 0.48 0.85 53 59623 11 1 8 2 57
ASE_00012 0.41 0.18 0.96 22 73897 1 0 1 0 101
ASE_00018 0.55 0.40 0.75 54 80529 20 1 17 2 80
ASE_00020 0.40 0.24 0.68 30 73876 16 1 13 2 96
ASE_00021 0.37 0.18 0.80 28 104161 7 1 6 0 132
ASE_00022 0.45 0.28 0.71 35 82979 14 1 13 0 89
ASE_00028 0.59 0.41 0.84 52 84604 11 3 7 1 74
ASE_00035 0.46 0.29 0.74 34 70454 12 1 11 0 84
ASE_00037 0.55 0.42 0.72 46 59276 18 0 18 0 64
ASE_00038 0.51 0.37 0.73 37 53577 14 1 13 0 64
ASE_00040 0.44 0.24 0.80 32 78963 9 1 7 1 101
ASE_00041 0.54 0.38 0.77 41 57577 12 0 12 0 67
ASE_00042 0.40 0.18 0.90 26 90071 3 0 3 0 119
ASE_00044 0.45 0.29 0.71 30 54573 13 0 12 1 75
ASE_00064 0.48 0.30 0.75 27 45415 10 1 8 1 62
ASE_00068 0.61 0.44 0.86 37 37632 6 0 6 0 48
ASE_00074 0.63 0.44 0.91 52 67839 6 0 5 1 67
ASE_00075 0.37 0.17 0.80 28 108776 7 1 6 0 134
ASE_00077 0.59 0.36 0.97 31 45118 1 0 1 0 55
ASE_00078 0.72 0.61 0.84 51 43010 11 1 9 1 32
ASE_00080 0.37 0.24 0.58 30 71579 22 0 22 0 93
ASE_00081 0.51 0.31 0.86 30 49735 6 0 5 1 67
ASE_00082 0.56 0.39 0.82 45 70445 17 0 10 7 71
ASE_00083 0.50 0.27 0.91 30 62448 4 0 3 1 80
ASE_00084 0.49 0.34 0.69 34 53579 15 0 15 0 65
ASE_00087 0.41 0.21 0.79 30 88372 8 0 8 0 114
ASE_00090 0.46 0.33 0.66 33 55561 18 0 17 1 68
ASE_00092 0.55 0.37 0.81 42 63494 11 0 10 1 71
ASE_00099 0.55 0.40 0.76 48 64557 17 0 15 2 72
ASE_00104 0.47 0.30 0.73 36 64212 14 0 13 1 83
ASE_00105 0.42 0.23 0.78 25 64229 7 1 6 0 86
ASE_00107 0.62 0.45 0.85 57 73086 10 0 10 0 70
ASE_00115 0.51 0.29 0.91 29 54583 4 0 3 1 72
ASE_00118 0.65 0.48 0.88 49 60670 9 1 6 2 53
ASE_00119 0.44 0.29 0.67 31 62789 17 3 12 2 77
ASE_00123 0.45 0.28 0.71 24 38469 14 0 10 4 61
ASE_00125 0.55 0.40 0.76 35 39294 12 1 10 1 53
ASE_00126 0.66 0.56 0.78 46 40411 14 0 13 1 36
ASE_00128 0.51 0.29 0.91 29 53269 4 0 3 1 71
ASE_00129 0.51 0.27 0.97 30 62804 1 0 1 0 81
ASE_00131 0.53 0.34 0.83 29 39305 7 0 6 1 56
ASE_00134 0.63 0.48 0.82 46 50347 11 0 10 1 49
ASE_00135 0.47 0.34 0.65 37 63133 20 1 19 0 72
ASE_00136 0.63 0.50 0.81 46 48148 13 0 11 2 46
ASE_00137 0.67 0.50 0.89 49 48461 7 2 4 1 49
ASE_00138 0.74 0.63 0.86 51 40411 9 1 7 1 30
ASE_00140 0.35 0.18 0.69 22 70844 11 0 10 1 103
ASE_00142 0.46 0.22 0.96 27 67133 3 0 1 2 95
ASE_00146 0.52 0.38 0.70 47 70809 20 1 19 0 77
ASE_00153 0.09 0.05 0.16 4 57605 39 5 16 18 69
ASE_00163 0.67 0.54 0.83 50 53241 10 1 9 0 43
ASE_00165 0.54 0.31 0.97 31 52943 1 0 1 0 70
ASE_00170 0.52 0.32 0.83 30 48792 8 0 6 2 63
ASE_00171 0.64 0.48 0.85 45 48463 9 1 7 1 49
ASE_00172 0.53 0.38 0.74 40 58942 15 1 13 1 66
ASE_00174 0.39 0.19 0.81 21 61049 5 2 3 0 88
ASE_00175 0.46 0.32 0.65 34 59979 18 0 18 0 73
ASE_00179 0.55 0.45 0.67 38 44196 19 3 16 0 46
ASE_00180 0.69 0.57 0.84 57 51292 11 0 11 0 43
ASE_00181 0.50 0.30 0.82 32 57591 8 0 7 1 74
ASE_00182 0.40 0.26 0.64 35 84200 20 1 19 0 101
ASE_00183 0.42 0.26 0.67 29 61382 14 0 14 0 84
ASE_00184 0.63 0.47 0.86 48 54559 8 1 7 0 54
ASE_00185 0.35 0.18 0.70 23 73503 10 0 10 0 105
ASE_00186 0.44 0.27 0.71 36 78952 15 0 15 0 96
ASE_00190 0.32 0.18 0.57 16 45423 13 1 11 1 74
ASE_00197 0.45 0.26 0.78 38 89204 11 0 11 0 107
ASE_00198 0.62 0.46 0.84 47 52594 9 1 8 0 55
ASE_00203 0.44 0.24 0.79 23 46636 6 2 4 0 73
ASE_00212 0.43 0.27 0.69 40 93903 18 1 17 0 108
ASE_00214 0.62 0.47 0.81 48 56221 13 0 11 2 55
ASE_00215 0.42 0.27 0.66 27 48475 15 0 14 1 72
ASE_00216 0.72 0.60 0.86 49 39283 8 5 3 0 33
ASE_00217 0.54 0.38 0.77 34 40426 12 0 10 2 56
ASE_00221 0.56 0.38 0.80 45 64564 11 1 10 0 72
ASE_00228 0.41 0.24 0.70 21 46941 10 2 7 1 65
ASE_00229 0.57 0.44 0.75 38 42435 14 0 13 1 49
ASE_00231 0.61 0.45 0.83 43 47843 9 2 7 0 53
ASE_00232 0.66 0.56 0.78 47 38443 13 4 9 0 37
ASE_00234 0.45 0.27 0.74 35 75419 12 1 11 0 94
ASE_00238 0.46 0.22 0.96 25 64235 1 0 1 0 89
ASE_00241 0.77 0.68 0.88 59 43889 8 0 8 0 28
ASE_00242 0.58 0.41 0.81 46 61018 13 1 10 2 66
ASE_00248 0.56 0.39 0.80 44 62426 11 1 10 0 70
ASE_00254 0.65 0.55 0.76 45 36797 14 3 11 0 37
ASE_00255 0.42 0.22 0.82 28 74657 6 1 5 0 102
ASE_00257 0.51 0.36 0.73 35 50992 14 0 13 1 62
ASE_00263 0.50 0.33 0.78 39 70450 12 0 11 1 81
ASE_00267 0.62 0.47 0.82 41 45100 10 0 9 1 47
ASE_00270 0.47 0.27 0.80 35 72346 9 0 9 0 93
ASE_00274 0.56 0.42 0.75 43 55554 14 1 13 0 60
ASE_00277 0.49 0.27 0.89 25 48177 3 0 3 0 66
ASE_00279 0.50 0.27 0.93 27 53272 2 0 2 0 74
ASE_00280 0.45 0.30 0.67 29 51960 15 0 14 1 69
ASE_00281 0.49 0.30 0.81 26 44519 6 0 6 0 62
ASE_00282 0.45 0.30 0.68 38 77759 18 1 17 0 89
ASE_00283 0.46 0.26 0.82 28 61742 8 0 6 2 79
ASE_00284 0.41 0.24 0.70 26 58274 11 0 11 0 82
ASE_00285 0.43 0.22 0.82 27 68973 6 0 6 0 95
ASE_00286 0.66 0.51 0.85 47 46610 9 0 8 1 45
ASE_00287 0.44 0.31 0.63 32 54895 20 1 18 1 71
ASE_00292 0.50 0.35 0.72 48 81743 19 0 19 0 90
ASE_00294 0.37 0.19 0.74 32 114438 12 0 11 1 139
ASE_00296 0.35 0.18 0.67 26 91767 13 0 13 0 119
ASE_00297 0.40 0.24 0.65 24 52938 14 0 13 1 74
ASE_00298 0.54 0.38 0.75 43 67471 14 1 13 0 70
ASE_00318 0.49 0.31 0.80 36 80155 10 3 6 1 82
ASE_00328 0.48 0.34 0.69 38 72716 20 4 13 3 74
ASE_00332 0.41 0.20 0.87 27 81779 4 0 4 0 111
ASE_00335 0.46 0.32 0.67 37 75411 19 2 16 1 79
ASE_00340 0.47 0.36 0.62 31 46006 19 5 14 0 54
ASE_00342 0.57 0.41 0.81 47 62423 13 0 11 2 68
ASE_00353 0.52 0.39 0.68 42 57908 21 1 19 1 65
ASE_00361 0.40 0.21 0.75 27 75430 10 1 8 1 100
ASE_00362 0.52 0.41 0.66 37 48149 19 0 19 0 54
ASE_00363 0.48 0.30 0.78 28 51324 9 4 4 1 66
ASE_00364 0.43 0.25 0.76 26 54251 8 0 8 0 79
ASE_00366 0.43 0.33 0.56 32 58596 25 3 22 0 66
ASE_00367 0.50 0.30 0.84 26 43040 5 0 5 0 60
ASE_00369 0.55 0.38 0.79 41 55893 11 0 11 0 66
ASE_00370 0.69 0.57 0.83 48 41847 11 1 9 1 36
ASE_00372 0.60 0.43 0.84 43 51952 8 0 8 0 57
ASE_00374 0.52 0.32 0.85 28 44817 6 0 5 1 60
ASE_00376 0.42 0.25 0.70 26 56916 11 0 11 0 79
ASE_00377 0.43 0.25 0.75 27 57594 10 0 9 1 80
ASE_00379 0.60 0.44 0.83 39 46009 9 0 8 1 50
ASE_00382 0.64 0.51 0.81 43 41852 11 1 9 1 41
ASE_00383 0.55 0.38 0.78 40 54564 11 1 10 0 65
ASE_00384 0.49 0.28 0.87 26 48486 5 0 4 1 66
ASE_00386 0.54 0.31 0.94 30 50371 3 0 2 1 66
ASE_00387 0.42 0.23 0.75 24 55913 9 0 8 1 80
ASE_00388 0.68 0.55 0.84 49 45695 10 1 8 1 40
ASE_00390 0.55 0.33 0.93 28 42165 3 0 2 1 57
ASE_00393 0.58 0.45 0.74 42 47838 15 1 14 0 51
ASE_00394 0.54 0.31 0.94 29 46940 3 0 2 1 64
ASE_00395 0.61 0.48 0.78 40 41565 11 0 11 0 44
ASE_00396 0.56 0.34 0.93 28 41586 3 0 2 1 55
ASE_00397 0.55 0.38 0.78 40 54564 12 0 11 1 65
ASE_00398 0.44 0.23 0.86 24 55917 5 0 4 1 80
ASE_00400 0.58 0.43 0.78 46 57911 13 1 12 0 60
ASE_00401 0.43 0.21 0.90 26 76999 4 0 3 1 100
ASE_00402 0.54 0.36 0.79 31 42447 8 0 8 0 54
ASE_00403 0.61 0.42 0.88 45 55894 6 1 5 0 62
ASE_00404 0.68 0.56 0.83 48 43013 10 1 9 0 37
ASE_00406 0.59 0.41 0.85 39 48782 9 0 7 2 55
ASE_00411 0.44 0.33 0.59 29 49406 20 1 19 0 60
ASE_00412 0.53 0.36 0.79 38 58263 11 0 10 1 67
ASE_00413 0.51 0.37 0.70 30 44508 14 3 10 1 51
ASE_00415 0.39 0.20 0.75 21 54918 8 0 7 1 82
ASE_00416 0.42 0.21 0.82 27 77388 7 0 6 1 100
ASE_00419 0.55 0.41 0.75 42 54890 14 2 12 0 61
ASE_00422 0.57 0.40 0.79 38 46923 11 0 10 1 56
ASE_00423 0.39 0.24 0.63 26 56912 15 0 15 0 83
ASE_00428 0.56 0.40 0.79 50 76573 13 1 12 0 75
ASE_00430 0.46 0.25 0.86 24 46943 4 0 4 0 73
ASE_00437 0.58 0.39 0.87 53 79340 8 0 8 0 82
ASE_00441 0.53 0.36 0.80 40 64211 11 1 9 1 72
ASE_00448 0.51 0.33 0.79 37 64214 11 0 10 1 75
ASE_00451 0.54 0.35 0.83 44 70823 10 1 8 1 81
PDB_00571 0.87 0.80 0.95 20 3300 1 0 1 0 5
PDB_00828 0.84 0.70 1.00 19 2466 0 0 0 0 8
PDB_00829 0.84 0.71 1.00 17 2261 0 0 0 0 7
PDB_01020 0.78 0.61 1.00 14 2264 0 0 0 0 9
PDB_01073 0.59 0.35 1.00 12 4359 1 0 0 1 22
RFA_00599 0.06 0.04 0.10 4 101435 37 2 34 1 107
RFA_00601 0.20 0.13 0.32 15 99188 37 2 30 5 99
RFA_00602 0.15 0.09 0.26 10 101437 34 0 28 6 106
TMR_00017 0.44 0.23 0.85 23 67134 8 0 4 4 79
TMR_00018 0.29 0.13 0.67 12 64602 10 0 6 4 80
TMR_00038 0.49 0.25 0.93 28 71223 4 1 1 2 82
TMR_00042 0.22 0.12 0.40 12 62805 21 0 18 3 86
TMR_00046 0.31 0.22 0.44 21 62787 30 4 23 3 75
TMR_00048 0.28 0.20 0.40 19 64933 33 5 23 5 76
TMR_00080 0.47 0.29 0.76 28 70463 9 0 9 0 68
TMR_00082 0.44 0.30 0.63 29 67850 21 1 16 4 67
TMR_00123 0.41 0.22 0.76 22 66401 12 0 7 5 79
TMR_00137 0.33 0.20 0.55 18 61042 21 2 13 6 71
TMR_00142 0.12 0.07 0.21 7 70843 33 8 18 7 95
TMR_00207 0.32 0.18 0.54 19 72355 16 6 10 0 84
TMR_00257 0.46 0.29 0.76 28 67124 14 0 9 5 70
TMR_00271 0.28 0.14 0.57 13 64238 15 1 9 5 78
TMR_00332 0.40 0.22 0.71 22 67130 14 0 9 5 77
TMR_00366 0.32 0.17 0.59 17 67867 23 3 9 11 83
TMR_00378 0.32 0.18 0.59 17 67867 23 3 9 11 80
TMR_00399 0.18 0.09 0.36 8 64958 14 7 7 0 86
TMR_00404 0.21 0.11 0.42 10 67504 25 4 10 11 82
TMR_00427 0.55 0.32 0.94 31 67495 7 0 2 5 66
TMR_00443 0.41 0.27 0.64 28 67117 20 1 15 4 76
TMR_00451 0.17 0.11 0.25 10 63506 34 6 24 4 79
TMR_00458 0.18 0.09 0.38 8 63525 16 1 12 3 85
TMR_00469 0.50 0.31 0.79 31 64581 12 1 7 4 69
TMR_00472 0.50 0.30 0.83 29 64585 10 1 5 4 68
TMR_00519 0.28 0.18 0.44 17 63151 27 2 20 5 78
TMR_00520 0.34 0.19 0.59 19 63158 13 4 9 0 80
TMR_00522 0.38 0.20 0.73 19 63164 7 1 6 0 78
TMR_00528 0.40 0.23 0.71 22 63159 13 2 7 4 75
TMR_00540 0.30 0.18 0.50 19 73498 24 2 17 5 85
TMR_00568 0.33 0.17 0.65 17 60700 14 0 9 5 82
TMR_00571 0.37 0.19 0.70 19 60699 13 0 8 5 80
TMR_00580 0.35 0.19 0.66 19 60697 15 2 8 5 81
TMR_00584 0.31 0.15 0.63 15 61051 15 1 8 6 82
TMR_00586 0.36 0.20 0.68 19 61047 14 1 8 5 78
TMR_00616 0.46 0.28 0.76 28 67124 12 3 6 3 71
TMR_00699 0.32 0.17 0.61 17 67133 12 3 8 1 85
TMR_00702 0.42 0.24 0.73 24 67128 10 3 6 1 76
TMR_00703 0.52 0.35 0.78 35 67483 15 1 9 5 64

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.