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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of Afold - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & Afold [.zip] - may take several seconds...


Overview

Metric MXScarna(20) Afold
MCC 0.612 > 0.453
Average MCC ± 95% Confidence Intervals 0.632 ± 0.016 > 0.504 ± 0.020
Sensitivity 0.551 > 0.449
Positive Predictive Value 0.680 > 0.458
Total TP 28196 > 22979
Total TN 108063114 > 108054370
Total FP 17693 < 30435
Total FP CONTRA 2100 < 4084
Total FP INCONS 11158 < 23135
Total FP COMP 4435 > 3216
Total FN 23008 < 28225
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of MXScarna(20) and Afold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and Afold).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for MXScarna(20) and Afold).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and Afold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and Afold).

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Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 28196
Total TN 108063114
Total FP 17693
Total FP CONTRA 2100
Total FP INCONS 11158
Total FP COMP 4435
Total FN 23008
Total Scores
MCC 0.612
Average MCC ± 95% Confidence Intervals 0.632 ± 0.016
Sensitivity 0.551
Positive Predictive Value 0.680
Nr of predictions 228

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.70 0.61 0.80 59 47821 19 2 13 4 38
ASE_00005 0.77 0.64 0.93 75 57889 11 1 5 5 42
ASE_00006 0.52 0.47 0.58 44 47510 34 6 26 2 49
ASE_00007 0.71 0.66 0.77 73 59590 26 2 20 4 37
ASE_00012 0.75 0.66 0.84 81 73824 18 2 13 3 42
ASE_00020 0.58 0.46 0.74 58 73842 24 3 17 4 68
ASE_00021 0.74 0.63 0.88 101 104081 17 2 12 3 59
ASE_00028 0.78 0.70 0.87 88 84565 21 4 9 8 38
ASE_00037 0.77 0.70 0.86 77 59250 18 0 13 5 33
ASE_00038 0.52 0.45 0.62 45 53555 32 3 25 4 56
ASE_00040 0.62 0.55 0.70 73 78899 38 3 28 7 60
ASE_00041 0.74 0.63 0.86 68 57551 17 1 10 6 40
ASE_00042 0.78 0.70 0.86 102 89982 21 3 13 5 43
ASE_00044 0.82 0.75 0.90 79 54527 13 4 5 4 26
ASE_00064 0.70 0.60 0.83 53 45387 22 1 10 11 36
ASE_00068 0.79 0.68 0.91 58 37611 11 2 4 5 27
ASE_00074 0.72 0.63 0.82 75 67805 21 1 15 5 44
ASE_00075 0.60 0.47 0.77 76 108712 26 4 19 3 86
ASE_00077 0.74 0.70 0.78 60 45073 22 3 14 5 26
ASE_00078 0.77 0.69 0.86 57 43005 17 2 7 8 26
ASE_00080 0.40 0.33 0.48 40 71548 48 5 38 5 83
ASE_00081 0.74 0.67 0.82 65 49691 24 1 13 10 32
ASE_00082 0.41 0.34 0.51 39 70424 44 4 33 7 77
ASE_00083 0.74 0.67 0.81 74 62390 24 2 15 7 36
ASE_00084 0.60 0.49 0.72 49 53560 28 2 17 9 50
ASE_00087 0.42 0.31 0.59 44 88335 37 2 29 6 100
ASE_00090 0.58 0.50 0.68 50 55538 27 1 22 4 51
ASE_00092 0.62 0.52 0.74 59 63466 28 6 15 7 54
ASE_00104 0.73 0.66 0.81 79 64164 25 1 17 7 40
ASE_00115 0.36 0.28 0.46 28 54554 38 2 31 5 73
ASE_00118 0.51 0.40 0.64 41 60662 33 1 22 10 61
ASE_00119 0.32 0.23 0.44 25 62778 34 0 32 2 83
ASE_00123 0.49 0.35 0.68 30 38459 16 3 11 2 55
ASE_00125 0.61 0.43 0.86 38 39296 11 0 6 5 50
ASE_00126 0.85 0.82 0.89 67 40395 15 2 6 7 15
ASE_00128 0.69 0.56 0.86 56 53236 14 2 7 5 44
ASE_00129 0.68 0.63 0.74 70 62740 28 3 22 3 41
ASE_00131 0.60 0.46 0.78 39 39290 20 1 10 9 46
ASE_00134 0.60 0.52 0.70 49 50333 29 1 20 8 46
ASE_00135 0.44 0.35 0.56 38 63122 41 1 29 11 71
ASE_00136 0.70 0.62 0.78 57 48132 24 1 15 8 35
ASE_00137 0.65 0.57 0.75 56 48441 23 3 16 4 42
ASE_00138 0.67 0.60 0.74 49 40404 27 1 16 10 32
ASE_00140 0.53 0.41 0.68 51 70801 28 4 20 4 74
ASE_00146 0.61 0.51 0.74 63 70791 29 1 21 7 61
ASE_00153 0.52 0.45 0.60 33 57575 51 2 20 29 40
ASE_00163 0.71 0.61 0.83 57 53232 17 3 9 5 36
ASE_00165 0.53 0.45 0.64 45 52905 29 3 22 4 56
ASE_00170 0.55 0.51 0.59 47 48749 35 5 27 3 46
ASE_00171 0.46 0.41 0.51 39 48439 42 1 37 4 55
ASE_00172 0.71 0.58 0.87 61 58926 15 2 7 6 45
ASE_00174 0.42 0.34 0.53 37 61005 39 3 30 6 72
ASE_00175 0.68 0.60 0.78 64 59949 26 3 15 8 43
ASE_00179 0.76 0.69 0.83 58 44183 18 4 8 6 26
ASE_00180 0.72 0.64 0.82 64 51282 20 3 11 6 36
ASE_00181 0.67 0.58 0.79 61 57553 24 6 10 8 45
ASE_00182 0.42 0.32 0.57 43 84179 38 2 31 5 93
ASE_00183 0.67 0.58 0.79 65 61343 24 0 17 7 48
ASE_00185 0.50 0.37 0.69 47 73468 24 3 18 3 81
ASE_00186 0.76 0.68 0.84 90 78896 20 1 16 3 42
ASE_00190 0.52 0.42 0.64 38 45392 24 5 16 3 52
ASE_00197 0.67 0.58 0.79 84 89146 27 2 21 4 61
ASE_00198 0.75 0.69 0.81 70 52564 20 4 12 4 32
ASE_00203 0.70 0.60 0.82 58 46594 17 3 10 4 38
ASE_00212 0.76 0.68 0.85 100 93844 23 3 14 6 48
ASE_00214 0.78 0.71 0.86 73 56195 16 4 8 4 30
ASE_00215 0.24 0.19 0.30 19 48453 48 6 38 4 80
ASE_00216 0.83 0.76 0.91 62 39272 13 1 5 7 20
ASE_00217 0.64 0.59 0.69 53 40393 31 1 23 7 37
ASE_00221 0.64 0.59 0.69 69 64520 34 1 30 3 48
ASE_00228 0.69 0.64 0.75 55 46898 26 4 14 8 31
ASE_00229 0.79 0.70 0.88 61 42417 14 3 5 6 26
ASE_00231 0.57 0.46 0.70 44 47832 24 1 18 5 52
ASE_00232 0.82 0.73 0.92 61 38437 10 3 2 5 23
ASE_00234 0.59 0.47 0.73 61 75383 27 3 19 5 68
ASE_00238 0.61 0.49 0.77 56 64188 22 4 13 5 58
ASE_00241 0.79 0.69 0.91 60 43890 12 1 5 6 27
ASE_00254 0.75 0.65 0.87 53 36795 12 4 4 4 29
ASE_00255 0.65 0.59 0.71 77 74583 34 3 28 3 53
ASE_00257 0.60 0.52 0.70 50 50969 30 3 18 9 47
ASE_00263 0.54 0.43 0.68 52 70424 27 4 20 3 68
ASE_00267 0.75 0.67 0.84 59 45080 20 1 10 9 29
ASE_00270 0.43 0.30 0.61 38 72328 27 1 23 3 90
ASE_00274 0.66 0.50 0.85 52 55550 14 2 7 5 51
ASE_00277 0.73 0.56 0.96 51 48152 6 0 2 4 40
ASE_00279 0.78 0.71 0.86 72 53217 19 3 9 7 29
ASE_00280 0.64 0.57 0.72 56 51925 32 1 21 10 42
ASE_00282 0.51 0.44 0.59 56 77720 43 3 36 4 71
ASE_00283 0.61 0.51 0.73 55 61701 25 3 17 5 52
ASE_00284 0.66 0.53 0.81 57 58241 15 2 11 2 51
ASE_00285 0.58 0.48 0.70 58 68923 28 4 21 3 64
ASE_00286 0.63 0.57 0.70 52 46591 31 1 21 9 40
ASE_00287 0.71 0.64 0.79 66 54862 25 3 15 7 37
ASE_00292 0.66 0.59 0.73 82 81697 39 2 29 8 56
ASE_00294 0.68 0.59 0.79 101 114353 34 1 26 7 70
ASE_00296 0.64 0.54 0.75 79 91700 32 5 22 5 66
ASE_00297 0.57 0.49 0.66 48 52902 30 3 22 5 50
ASE_00298 0.46 0.40 0.54 45 67445 43 7 31 5 68
ASE_00328 0.71 0.66 0.77 74 72675 33 5 17 11 38
ASE_00332 0.81 0.74 0.89 102 81695 17 4 9 4 36
ASE_00340 0.54 0.47 0.62 40 45991 32 4 21 7 45
ASE_00342 0.81 0.75 0.88 86 62383 19 1 11 7 29
ASE_00361 0.56 0.41 0.78 52 75399 19 1 14 4 75
ASE_00362 0.71 0.62 0.82 56 48137 18 3 9 6 35
ASE_00363 0.69 0.57 0.82 54 51294 22 2 10 10 40
ASE_00364 0.67 0.58 0.76 61 54205 25 3 16 6 44
ASE_00366 0.56 0.49 0.65 48 58579 29 4 22 3 50
ASE_00367 0.75 0.70 0.81 60 42997 20 3 11 6 26
ASE_00369 0.58 0.50 0.66 54 55863 33 1 27 5 53
ASE_00370 0.87 0.82 0.92 69 41830 14 0 6 8 15
ASE_00372 0.48 0.41 0.55 41 51929 36 4 29 3 59
ASE_00374 0.72 0.63 0.82 55 44783 15 2 10 3 33
ASE_00376 0.55 0.51 0.60 54 56863 38 3 33 2 51
ASE_00379 0.72 0.69 0.76 61 45976 22 3 16 3 28
ASE_00382 0.67 0.62 0.73 52 41834 29 1 18 10 32
ASE_00383 0.79 0.71 0.88 75 54530 17 2 8 7 30
ASE_00384 0.61 0.53 0.71 49 48447 24 2 18 4 43
ASE_00386 0.71 0.63 0.80 60 50328 22 1 14 7 36
ASE_00387 0.62 0.55 0.71 57 55865 27 6 17 4 47
ASE_00388 0.66 0.56 0.78 50 45689 20 1 13 6 39
ASE_00390 0.77 0.68 0.87 58 42128 15 2 7 6 27
ASE_00393 0.68 0.59 0.77 55 47824 21 1 15 5 38
ASE_00394 0.72 0.62 0.83 58 46901 19 4 8 7 35
ASE_00395 0.74 0.64 0.86 54 41553 20 1 8 11 30
ASE_00396 0.71 0.63 0.80 52 41551 19 4 9 6 31
ASE_00397 0.80 0.70 0.91 74 54534 12 0 7 5 31
ASE_00398 0.51 0.43 0.61 45 55871 38 1 28 9 59
ASE_00400 0.51 0.42 0.61 45 57896 33 3 26 4 61
ASE_00401 0.50 0.40 0.62 51 76946 36 4 27 5 75
ASE_00402 0.66 0.59 0.74 50 42418 21 1 17 3 35
ASE_00403 0.71 0.61 0.83 65 55867 19 3 10 6 42
ASE_00404 0.79 0.71 0.90 60 43004 10 0 7 3 25
ASE_00411 0.54 0.46 0.63 41 49390 27 2 22 3 48
ASE_00413 0.65 0.60 0.69 49 44480 29 5 17 7 32
ASE_00415 0.42 0.35 0.51 36 54876 37 1 33 3 67
ASE_00416 0.59 0.51 0.68 65 77325 36 6 25 5 62
ASE_00419 0.59 0.49 0.71 50 54876 23 1 19 3 53
ASE_00422 0.74 0.63 0.87 59 46903 14 2 7 5 35
ASE_00428 0.64 0.58 0.70 73 76532 38 6 25 7 52
ASE_00430 0.69 0.59 0.81 57 46901 18 2 11 5 40
ASE_00437 0.59 0.50 0.69 68 79302 35 0 31 4 67
ASE_00441 0.44 0.34 0.58 38 64196 33 1 26 6 74
ASE_00448 0.64 0.58 0.71 65 64169 33 1 26 6 47
ASE_00451 0.79 0.70 0.89 87 70778 16 3 8 5 38
CRW_00024 0.84 0.81 0.87 369 1085176 107 10 46 51 89
CRW_00048 0.72 0.67 0.78 317 1170807 127 11 80 36 153
CRW_00054 0.68 0.63 0.74 288 1107425 137 16 87 34 168
CRW_00059 0.72 0.66 0.78 312 1172344 127 16 74 37 161
CRW_00061 0.73 0.66 0.81 316 1181563 109 13 61 35 160
CRW_00068 0.69 0.64 0.74 293 1108909 137 18 85 34 164
CRW_00096 0.75 0.68 0.81 318 1178489 108 6 67 35 147
CRW_00140 0.76 0.71 0.81 328 1135874 114 12 64 38 135
CRW_00141 0.69 0.64 0.75 305 1201619 132 14 87 31 171
CRW_00150 0.72 0.65 0.80 303 1152540 113 14 64 35 163
CRW_00152 0.76 0.70 0.82 332 1180009 110 11 64 35 139
CRW_00166 0.65 0.60 0.71 281 1190800 160 10 105 45 187
CRW_00173 0.57 0.52 0.63 232 1082285 168 19 120 29 213
CRW_00177 0.62 0.56 0.68 264 1178492 152 16 108 28 209
CRW_00196 0.73 0.67 0.80 319 1207837 117 10 69 38 156
CRW_00230 0.73 0.67 0.80 319 1198526 122 12 69 41 159
CRW_00245 0.73 0.67 0.81 302 1105955 106 13 58 35 151
CRW_00248 0.71 0.65 0.77 317 1218729 129 13 82 34 167
CRW_00250 0.73 0.67 0.79 321 1198521 119 12 72 35 157
CRW_00256 0.70 0.64 0.77 299 1192353 124 11 77 36 169
CRW_00270 0.72 0.67 0.77 306 1111891 121 14 75 32 149
CRW_00271 0.70 0.65 0.77 298 1122364 122 17 72 33 164
CRW_00273 0.68 0.62 0.74 277 1085225 135 13 86 36 169
CRW_00275 0.71 0.63 0.80 289 1114908 114 13 61 40 168
CRW_00277 0.68 0.63 0.73 286 1110405 132 17 87 28 167
CRW_00278 0.71 0.62 0.80 280 1129906 107 12 58 37 170
CRW_00279 0.70 0.64 0.77 299 1180027 133 10 80 43 165
CRW_00280 0.72 0.66 0.78 301 1117875 125 10 74 41 152
CRW_00281 0.71 0.65 0.78 303 1144954 117 13 71 33 161
CRW_00284 0.69 0.62 0.77 281 1131397 117 9 73 35 175
CRW_00285 0.70 0.64 0.77 292 1117883 123 15 70 38 166
CRW_00289 0.62 0.58 0.66 274 1189239 172 18 122 32 202
CRW_00298 0.48 0.46 0.51 226 1620454 284 45 175 64 268
CRW_00301 0.42 0.39 0.45 204 1762046 308 49 204 55 315
CRW_00310 0.45 0.41 0.49 212 1805516 285 39 183 63 309
CRW_00326 0.49 0.45 0.53 227 1627679 267 35 169 63 275
CRW_00330 0.41 0.37 0.45 190 1988597 294 32 196 66 327
CRW_00332 0.37 0.34 0.40 163 1769615 307 47 196 64 314
CRW_00333 0.31 0.26 0.35 136 1892099 328 47 203 78 378
CRW_00345 0.46 0.44 0.49 219 1586422 293 53 177 63 279
CRW_00348 0.49 0.47 0.52 235 1615052 277 51 165 61 268
CRW_00358 0.48 0.44 0.53 224 1674941 262 38 162 62 283
CRW_00366 0.42 0.40 0.43 195 1579299 332 47 212 73 287
CRW_00370 0.50 0.48 0.52 242 1640302 281 47 175 59 264
CRW_00371 0.49 0.46 0.53 229 1611474 266 39 168 59 267
CRW_00372 0.51 0.47 0.54 236 1625872 273 37 161 75 262
CRW_00379 0.37 0.33 0.42 175 2126532 323 40 206 77 359
CRW_00386 0.47 0.43 0.50 223 1750812 281 44 177 60 292
CRW_00403 0.45 0.41 0.48 192 1606131 304 37 168 99 272
CRW_00411 0.49 0.46 0.52 227 1615066 271 42 168 61 269
CRW_00414 0.39 0.37 0.41 181 1665782 316 50 212 54 314
CRW_00466 0.63 0.58 0.69 266 1116382 147 16 101 30 192
CRW_00589 0.69 0.62 0.76 277 1094097 130 6 80 44 168
CRW_00590 0.72 0.67 0.78 303 1119366 134 11 76 47 149
CRW_00591 0.74 0.68 0.81 303 1098531 115 7 62 46 143
CRW_00598 0.49 0.46 0.52 226 1665793 276 41 165 70 265
CRW_00758 0.46 0.43 0.48 207 1640338 292 44 177 71 276
CRW_00759 0.42 0.40 0.44 191 1636712 314 43 199 72 290
CRW_00760 0.46 0.43 0.49 208 1638533 291 37 177 77 278
CRW_00772 0.60 0.54 0.67 217 945677 148 10 96 42 187
CRW_00789 0.67 0.60 0.75 268 1137427 134 8 83 43 179
CRW_00795 0.63 0.57 0.71 224 1152605 176 10 82 84 170
CRW_00849 0.61 0.55 0.68 260 1117878 154 17 105 32 210
CRW_01153 0.44 0.42 0.46 211 1606072 295 46 199 50 292
CRW_01171 0.48 0.45 0.51 229 1593556 274 47 173 54 277
CRW_01300 0.47 0.45 0.50 230 1693258 286 45 187 54 285
PDB_00571 0.76 0.68 0.85 17 3301 3 1 2 0 8
PDB_00703 0.69 0.60 0.79 295 1073472 114 10 68 36 200
PDB_00828 0.86 0.74 1.00 20 2465 0 0 0 0 7
PDB_00829 0.89 0.79 1.00 19 2259 0 0 0 0 5
PDB_00854 0.62 0.51 0.75 274 1500415 142 2 87 53 261
PDB_01088 0.66 0.56 0.78 308 1471077 135 7 78 50 239
PDB_01103 0.61 0.52 0.71 293 1606118 156 16 101 39 269
PDB_01105 0.64 0.54 0.75 291 1433583 134 3 94 37 249
PDB_01120 0.66 0.57 0.76 302 1204732 134 11 83 40 225
PDB_01273 0.69 0.60 0.79 294 1117886 120 10 70 40 197
RFA_00599 0.55 0.52 0.58 58 101375 62 5 37 20 53
RFA_00601 0.81 0.80 0.81 91 99123 42 5 16 21 23
RFA_00602 0.72 0.72 0.73 83 101361 51 6 25 20 33
TMR_00038 0.70 0.62 0.80 68 71168 24 8 9 7 42
TMR_00046 0.56 0.55 0.57 53 62742 46 5 35 6 43
TMR_00048 0.53 0.52 0.55 49 64891 48 7 33 8 46
TMR_00458 0.39 0.38 0.41 35 63460 51 20 31 0 58
TMR_00568 0.57 0.53 0.61 52 60641 45 4 29 12 47

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Performance of Afold - scored lower in this pairwise comparison

1. Total counts & total scores for Afold

Total Base Pair Counts
Total TP 22979
Total TN 108054370
Total FP 30435
Total FP CONTRA 4084
Total FP INCONS 23135
Total FP COMP 3216
Total FN 28225
Total Scores
MCC 0.453
Average MCC ± 95% Confidence Intervals 0.504 ± 0.020
Sensitivity 0.449
Positive Predictive Value 0.458
Nr of predictions 228

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2. Individual counts for Afold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.51 0.52 0.51 50 47797 49 10 38 1 47
ASE_00005 0.61 0.56 0.66 66 57870 39 0 34 5 51
ASE_00006 0.66 0.67 0.65 62 47491 36 7 26 3 31
ASE_00007 0.56 0.53 0.59 58 59586 45 1 40 4 52
ASE_00012 0.41 0.39 0.43 48 73808 72 1 63 8 75
ASE_00020 0.57 0.54 0.60 68 73807 46 6 39 1 58
ASE_00021 0.54 0.51 0.59 81 104058 66 7 50 9 79
ASE_00028 0.58 0.56 0.61 70 84551 54 4 41 9 56
ASE_00037 0.34 0.32 0.37 35 59245 63 0 60 3 75
ASE_00038 0.53 0.52 0.54 53 53529 48 4 42 2 48
ASE_00040 0.50 0.47 0.53 63 78883 63 5 52 6 70
ASE_00041 0.53 0.51 0.55 55 57530 51 2 43 6 53
ASE_00042 0.44 0.42 0.47 61 89969 73 3 67 3 84
ASE_00044 0.74 0.70 0.78 74 54520 26 3 18 5 31
ASE_00064 0.43 0.43 0.44 38 45364 54 5 44 5 51
ASE_00068 0.33 0.32 0.36 27 37599 50 2 47 1 58
ASE_00074 0.48 0.47 0.50 56 67784 57 7 49 1 63
ASE_00075 0.65 0.59 0.72 95 108679 46 3 34 9 67
ASE_00077 0.52 0.51 0.54 44 45068 39 6 32 1 42
ASE_00078 0.67 0.67 0.67 56 42988 32 5 22 5 27
ASE_00080 0.50 0.48 0.52 59 71518 59 3 51 5 64
ASE_00081 0.46 0.45 0.46 44 49675 53 5 46 2 53
ASE_00082 0.57 0.54 0.61 63 70396 51 1 40 10 53
ASE_00083 0.71 0.67 0.76 74 62383 32 1 23 8 36
ASE_00084 0.72 0.71 0.73 70 53532 30 6 20 4 29
ASE_00087 0.56 0.51 0.61 74 88288 54 5 43 6 70
ASE_00090 0.46 0.47 0.47 47 55510 59 6 48 5 54
ASE_00092 0.68 0.65 0.72 73 63444 35 3 26 6 40
ASE_00104 0.53 0.50 0.56 60 64153 49 8 40 1 59
ASE_00115 0.55 0.54 0.56 55 54517 51 1 42 8 46
ASE_00118 0.38 0.38 0.39 39 60625 64 5 57 2 63
ASE_00119 0.63 0.60 0.67 65 62738 35 1 31 3 43
ASE_00123 0.44 0.42 0.46 36 38425 48 3 39 6 49
ASE_00125 0.64 0.63 0.65 55 39255 32 4 26 2 33
ASE_00126 0.74 0.74 0.73 61 40387 27 3 19 5 21
ASE_00128 0.74 0.72 0.77 72 53207 30 2 20 8 28
ASE_00129 0.77 0.74 0.80 82 62732 26 3 18 5 29
ASE_00131 0.62 0.55 0.70 47 39273 31 0 20 11 38
ASE_00134 0.43 0.42 0.44 40 50313 54 7 43 4 55
ASE_00135 0.45 0.44 0.45 48 63084 63 8 50 5 61
ASE_00136 0.69 0.65 0.72 60 48122 28 3 20 5 32
ASE_00137 0.44 0.43 0.45 42 48423 53 4 47 2 56
ASE_00138 0.51 0.49 0.53 40 40395 36 4 31 1 41
ASE_00140 0.62 0.57 0.67 71 70770 38 6 29 3 54
ASE_00146 0.55 0.52 0.59 64 70768 50 2 42 6 60
ASE_00153 0.66 0.67 0.65 49 57555 68 2 24 42 24
ASE_00163 0.64 0.63 0.66 59 53211 43 4 27 12 34
ASE_00165 0.64 0.60 0.67 61 52884 31 5 25 1 40
ASE_00170 0.70 0.68 0.72 63 48740 27 2 23 2 30
ASE_00171 0.70 0.69 0.71 65 48425 28 5 21 2 29
ASE_00172 0.62 0.61 0.63 65 58893 41 8 30 3 41
ASE_00174 0.59 0.57 0.62 62 60975 42 6 32 4 47
ASE_00175 0.59 0.59 0.59 63 59925 45 7 36 2 44
ASE_00179 0.64 0.65 0.62 55 44164 35 7 27 1 29
ASE_00180 0.71 0.69 0.74 69 51267 31 2 22 7 31
ASE_00181 0.54 0.53 0.55 56 57528 52 3 43 6 50
ASE_00182 0.60 0.58 0.62 79 84128 49 6 42 1 57
ASE_00183 0.71 0.70 0.72 79 61316 35 2 28 5 34
ASE_00185 0.72 0.70 0.74 89 73416 38 6 25 7 39
ASE_00186 0.73 0.69 0.78 91 78887 30 3 22 5 41
ASE_00190 0.49 0.46 0.52 41 45372 44 7 31 6 49
ASE_00197 0.49 0.46 0.52 67 89123 66 4 59 3 78
ASE_00198 0.61 0.59 0.64 60 52556 40 6 28 6 42
ASE_00203 0.70 0.69 0.72 66 46573 26 7 19 0 30
ASE_00212 0.70 0.67 0.74 99 93827 39 3 32 4 49
ASE_00214 0.72 0.72 0.73 74 56178 36 4 24 8 29
ASE_00215 0.54 0.51 0.57 50 48429 39 4 33 2 49
ASE_00216 0.67 0.68 0.66 56 39255 31 9 20 2 26
ASE_00217 0.40 0.37 0.45 33 40396 48 3 38 7 57
ASE_00221 0.49 0.45 0.54 53 64522 48 3 42 3 64
ASE_00228 0.52 0.53 0.50 46 46879 46 14 32 0 40
ASE_00229 0.61 0.61 0.62 53 42400 33 8 25 0 34
ASE_00231 0.65 0.65 0.65 62 47800 33 5 28 0 34
ASE_00232 0.63 0.64 0.61 54 38415 37 10 24 3 30
ASE_00234 0.58 0.53 0.62 69 75355 47 3 39 5 60
ASE_00238 0.59 0.59 0.60 67 64150 50 2 42 6 47
ASE_00241 0.49 0.49 0.49 43 43868 47 7 38 2 44
ASE_00254 0.49 0.46 0.52 38 36783 39 4 31 4 44
ASE_00255 0.64 0.62 0.66 80 74570 45 7 34 4 50
ASE_00257 0.55 0.55 0.55 53 50944 47 4 39 4 44
ASE_00263 0.62 0.63 0.62 76 70377 49 5 42 2 44
ASE_00267 0.32 0.31 0.34 27 45070 62 5 48 9 61
ASE_00270 0.76 0.73 0.80 94 72272 29 4 20 5 34
ASE_00274 0.45 0.44 0.46 45 55513 54 10 43 1 58
ASE_00277 0.38 0.38 0.38 35 48112 61 9 49 3 56
ASE_00279 0.68 0.66 0.71 67 53206 35 3 25 7 34
ASE_00280 0.36 0.36 0.37 35 51909 65 4 55 6 63
ASE_00282 0.56 0.55 0.57 70 77693 58 5 47 6 57
ASE_00283 0.75 0.73 0.77 78 61675 30 3 20 7 29
ASE_00284 0.62 0.60 0.64 65 58210 44 4 32 8 43
ASE_00285 0.75 0.70 0.80 86 68899 28 3 18 7 36
ASE_00286 0.43 0.42 0.43 39 46574 63 5 47 11 53
ASE_00287 0.59 0.55 0.63 57 54856 39 2 31 6 46
ASE_00292 0.62 0.58 0.66 80 81689 43 2 39 2 58
ASE_00294 0.74 0.68 0.80 117 114335 32 2 27 3 54
ASE_00296 0.25 0.24 0.27 35 91676 98 8 87 3 110
ASE_00297 0.50 0.50 0.51 49 52878 53 4 44 5 49
ASE_00298 0.28 0.27 0.29 31 67420 79 9 68 2 82
ASE_00328 0.40 0.41 0.40 46 72656 75 3 66 6 66
ASE_00332 0.56 0.54 0.59 75 81682 55 2 51 2 63
ASE_00340 0.76 0.73 0.78 62 45977 26 6 11 9 23
ASE_00342 0.57 0.54 0.60 62 62378 41 5 36 0 53
ASE_00361 0.51 0.49 0.53 62 75349 59 7 48 4 65
ASE_00362 0.61 0.60 0.61 55 48115 39 6 29 4 36
ASE_00363 0.53 0.54 0.53 51 51263 47 5 41 1 43
ASE_00364 0.42 0.42 0.43 44 54182 63 4 55 4 61
ASE_00366 0.54 0.56 0.53 55 58549 52 10 39 3 43
ASE_00367 0.28 0.29 0.27 25 42979 68 8 59 1 61
ASE_00369 0.56 0.55 0.58 59 55843 44 4 39 1 48
ASE_00370 0.63 0.63 0.62 53 41820 33 7 25 1 31
ASE_00372 0.63 0.62 0.65 62 51907 39 6 28 5 38
ASE_00374 0.53 0.52 0.54 46 44765 40 8 31 1 42
ASE_00376 0.48 0.46 0.50 48 56857 52 4 44 4 57
ASE_00379 0.57 0.55 0.60 49 45974 41 3 30 8 40
ASE_00382 0.49 0.49 0.50 41 41823 45 6 35 4 43
ASE_00383 0.58 0.55 0.62 58 54521 40 3 33 4 47
ASE_00384 0.41 0.39 0.43 36 48432 58 2 46 10 56
ASE_00386 0.65 0.65 0.65 62 50307 41 3 31 7 34
ASE_00387 0.43 0.43 0.43 45 55841 59 6 53 0 59
ASE_00388 0.43 0.42 0.44 37 45669 53 3 44 6 52
ASE_00390 0.44 0.42 0.47 36 42118 52 6 35 11 49
ASE_00393 0.37 0.35 0.39 33 47811 58 2 49 7 60
ASE_00394 0.69 0.68 0.70 63 46881 29 5 22 2 30
ASE_00395 0.65 0.63 0.68 53 41538 35 1 24 10 31
ASE_00396 0.16 0.16 0.16 13 41535 71 2 66 3 70
ASE_00397 0.54 0.54 0.54 57 54510 51 4 44 3 48
ASE_00398 0.61 0.58 0.65 60 55852 37 1 32 4 44
ASE_00400 0.53 0.53 0.54 56 57866 51 7 41 3 50
ASE_00401 0.52 0.53 0.51 67 76897 65 13 51 1 59
ASE_00402 0.41 0.40 0.43 34 42406 52 7 39 6 51
ASE_00403 0.44 0.42 0.47 45 55849 55 4 47 4 62
ASE_00404 0.55 0.54 0.57 46 42990 43 0 35 8 39
ASE_00411 0.35 0.35 0.35 31 49366 63 7 51 5 58
ASE_00413 0.55 0.58 0.52 47 44461 44 13 30 1 34
ASE_00415 0.51 0.51 0.51 53 54843 53 7 43 3 50
ASE_00416 0.65 0.61 0.68 78 77307 43 0 36 7 49
ASE_00419 0.75 0.73 0.78 75 54850 26 5 16 5 28
ASE_00422 0.44 0.44 0.45 41 46880 56 5 45 6 53
ASE_00428 0.51 0.50 0.53 62 76520 58 5 49 4 63
ASE_00430 0.64 0.63 0.66 61 46878 39 5 27 7 36
ASE_00437 0.42 0.39 0.46 53 79285 64 4 59 1 82
ASE_00441 0.77 0.72 0.83 81 64163 30 1 16 13 31
ASE_00448 0.22 0.22 0.23 25 64150 91 6 80 5 87
ASE_00451 0.61 0.57 0.66 71 70768 40 2 35 3 54
CRW_00024 0.78 0.77 0.79 351 1085158 132 17 75 40 107
CRW_00048 0.49 0.49 0.50 228 1170758 252 20 209 23 242
CRW_00054 0.46 0.46 0.46 208 1107368 260 31 209 20 248
CRW_00059 0.52 0.51 0.53 240 1172289 233 26 191 16 233
CRW_00061 0.55 0.54 0.55 259 1181483 231 27 184 20 217
CRW_00068 0.49 0.49 0.50 226 1108849 247 24 206 17 231
CRW_00096 0.46 0.46 0.47 214 1178420 264 32 214 18 251
CRW_00140 0.64 0.63 0.64 291 1135826 182 20 141 21 172
CRW_00141 0.59 0.58 0.60 274 1201566 212 26 159 27 202
CRW_00150 0.42 0.41 0.42 193 1152465 282 35 228 19 273
CRW_00152 0.64 0.62 0.65 293 1179965 180 30 128 22 178
CRW_00166 0.54 0.53 0.55 248 1190745 226 28 175 23 220
CRW_00173 0.29 0.29 0.29 127 1082216 323 37 276 10 318
CRW_00177 0.44 0.43 0.45 203 1178433 259 22 222 15 270
CRW_00196 0.47 0.46 0.48 220 1207772 267 24 219 24 255
CRW_00230 0.57 0.56 0.58 266 1198467 216 21 172 23 212
CRW_00245 0.38 0.38 0.38 172 1105880 289 44 232 13 281
CRW_00248 0.57 0.57 0.58 274 1218666 234 21 180 33 210
CRW_00250 0.44 0.44 0.45 210 1198459 274 34 223 17 268
CRW_00256 0.41 0.40 0.42 188 1192291 278 39 222 17 280
CRW_00270 0.44 0.43 0.45 196 1111850 260 40 200 20 259
CRW_00271 0.51 0.50 0.51 231 1122302 237 43 175 19 231
CRW_00273 0.59 0.58 0.60 258 1085174 195 26 143 26 188
CRW_00275 0.47 0.47 0.48 213 1114826 258 28 204 26 244
CRW_00277 0.38 0.38 0.38 172 1110338 300 45 240 15 281
CRW_00278 0.41 0.40 0.42 180 1129825 274 33 218 23 270
CRW_00279 0.51 0.49 0.53 229 1179985 227 29 173 25 235
CRW_00280 0.51 0.50 0.51 227 1117817 231 28 188 15 226
CRW_00281 0.30 0.30 0.29 138 1144872 347 41 290 16 326
CRW_00284 0.28 0.27 0.28 124 1131316 337 30 290 17 332
CRW_00285 0.72 0.71 0.74 325 1117819 142 23 93 26 133
CRW_00289 0.46 0.45 0.48 214 1189204 258 34 201 23 262
CRW_00298 0.19 0.20 0.18 99 1620353 490 81 367 42 395
CRW_00301 0.30 0.31 0.30 162 1761957 428 86 298 44 357
CRW_00310 0.29 0.30 0.28 157 1805386 453 81 326 46 364
CRW_00326 0.41 0.41 0.42 204 1627621 339 47 238 54 298
CRW_00330 0.32 0.32 0.31 167 1988474 452 69 305 78 350
CRW_00332 0.18 0.20 0.17 94 1769479 492 105 343 44 383
CRW_00333 0.29 0.30 0.28 153 1891946 449 74 312 63 361
CRW_00345 0.34 0.35 0.33 175 1586340 403 71 285 47 323
CRW_00348 0.25 0.25 0.24 127 1614982 437 68 326 43 376
CRW_00358 0.36 0.36 0.35 183 1674845 391 61 276 54 324
CRW_00366 0.35 0.36 0.33 174 1579230 395 88 261 46 308
CRW_00370 0.28 0.28 0.28 143 1640248 420 77 298 45 363
CRW_00371 0.29 0.29 0.28 145 1611389 409 77 299 33 351
CRW_00372 0.36 0.36 0.35 181 1625787 378 59 279 40 317
CRW_00379 0.42 0.43 0.41 227 2126401 423 55 270 98 307
CRW_00386 0.24 0.25 0.23 129 1750683 478 83 361 34 386
CRW_00403 0.31 0.31 0.30 146 1606035 431 65 282 84 318
CRW_00411 0.34 0.34 0.34 169 1615006 381 62 266 53 327
CRW_00414 0.27 0.28 0.26 140 1665694 436 77 314 45 355
CRW_00466 0.60 0.59 0.62 268 1116330 196 21 146 29 190
CRW_00589 0.18 0.18 0.18 78 1094024 374 34 324 16 367
CRW_00590 0.36 0.36 0.37 161 1119326 290 30 239 21 291
CRW_00591 0.57 0.56 0.59 251 1098476 205 23 153 29 195
CRW_00598 0.31 0.33 0.29 162 1665675 440 88 300 52 329
CRW_00758 0.29 0.30 0.29 144 1640268 416 66 288 62 339
CRW_00759 0.22 0.22 0.21 107 1636633 462 78 327 57 374
CRW_00760 0.28 0.29 0.28 140 1638458 411 74 283 54 346
CRW_00772 0.26 0.25 0.26 103 945610 313 37 250 26 301
CRW_00789 0.36 0.36 0.36 160 1137342 302 44 240 18 287
CRW_00795 0.21 0.22 0.21 85 1152511 379 51 274 54 309
CRW_00849 0.49 0.48 0.49 227 1117798 259 23 212 24 243
CRW_01153 0.32 0.32 0.32 160 1606024 390 54 290 46 343
CRW_01171 0.32 0.33 0.31 167 1593473 402 81 284 37 339
CRW_01300 0.36 0.37 0.35 189 1693186 392 71 274 47 326
PDB_00571 -0.01 0.00 0.00 0 3302 20 5 14 1 25
PDB_00703 0.53 0.50 0.56 246 1073408 220 17 174 29 249
PDB_00828 0.88 0.78 1.00 21 2464 0 0 0 0 6
PDB_00829 0.82 0.71 0.94 17 2260 1 0 1 0 7
PDB_00854 0.55 0.53 0.56 284 1500271 276 22 201 53 251
PDB_01088 0.36 0.35 0.37 191 1470959 352 45 275 32 356
PDB_01103 0.56 0.54 0.58 306 1605999 254 32 191 31 256
PDB_01105 0.60 0.58 0.63 313 1433471 221 15 172 34 227
PDB_01120 0.46 0.43 0.49 228 1204659 250 31 210 9 299
PDB_01273 0.51 0.48 0.53 237 1117812 242 21 190 31 254
RFA_00599 0.67 0.70 0.64 78 101353 66 16 28 22 33
RFA_00601 0.09 0.11 0.08 12 99092 139 35 96 8 102
RFA_00602 0.50 0.53 0.47 62 101344 91 18 51 22 54
TMR_00038 0.25 0.25 0.25 28 71140 89 12 73 4 82
TMR_00046 0.47 0.48 0.46 46 62734 61 10 45 6 50
TMR_00048 0.35 0.37 0.34 35 64876 73 9 60 4 60
TMR_00458 0.22 0.22 0.23 20 63458 76 7 61 8 73
TMR_00568 0.57 0.57 0.58 56 60629 50 3 38 9 43

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.