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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric Multilign(20) Carnac(seed)
MCC 0.644 > 0.000
Average MCC ± 95% Confidence Intervals 0.643 ± 0.831 > 0.000 ± 0.000
Sensitivity 0.627 > 0.000
Positive Predictive Value 0.662 > 0.000
Total TP 141 > 0
Total TN 200497 < 200710
Total FP 100 > 0
Total FP CONTRA 23 > 0
Total FP INCONS 49 > 0
Total FP COMP 28 > 0
Total FN 84 < 225
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(20) and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(20) and Carnac(seed)).

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Performance of Multilign(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 141
Total TN 200497
Total FP 100
Total FP CONTRA 23
Total FP INCONS 49
Total FP COMP 28
Total FN 84
Total Scores
MCC 0.644
Average MCC ± 95% Confidence Intervals 0.643 ± 0.831
Sensitivity 0.627
Positive Predictive Value 0.662
Nr of predictions 2

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2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00599 0.71 0.71 0.71 79 101363 50 13 20 17 32
RFA_00601 0.58 0.54 0.61 62 99134 50 10 29 11 52

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 0
Total TN 200710
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 225
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 2

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00599 0.00 0.00 0.00 0 101475 0 0 0 0 111
RFA_00601 0.00 0.00 0.00 0 99235 0 0 0 0 114

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.