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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(20) - scored higher in this pairwise comparison

  4. Performance of IPknot - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(20) & IPknot [.zip] - may take several seconds...


Overview

Metric Multilign(20) IPknot
MCC 0.651 > 0.649
Average MCC ± 95% Confidence Intervals 0.656 ± 0.017 > 0.652 ± 0.018
Sensitivity 0.591 > 0.576
Positive Predictive Value 0.718 < 0.733
Total TP 11862 > 11566
Total TN 11495758 < 11496494
Total FP 5464 > 4818
Total FP CONTRA 615 < 642
Total FP INCONS 4034 > 3567
Total FP COMP 815 > 609
Total FN 8223 < 8519
P-value 0.231589081714

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Performance plots


  1. Comparison of performance of Multilign(20) and IPknot. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(20) and IPknot).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Multilign(20) and IPknot).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(20) and IPknot. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(20) and IPknot).

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Performance of Multilign(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 11862
Total TN 11495758
Total FP 5464
Total FP CONTRA 615
Total FP INCONS 4034
Total FP COMP 815
Total FN 8223
Total Scores
MCC 0.651
Average MCC ± 95% Confidence Intervals 0.656 ± 0.017
Sensitivity 0.591
Positive Predictive Value 0.718
Nr of predictions 196

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2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00005 0.73 0.66 0.82 77 57876 23 0 17 6 40
ASE_00006 0.78 0.76 0.81 71 47498 22 1 16 5 22
ASE_00007 0.70 0.63 0.78 69 59596 25 0 20 5 41
ASE_00012 0.62 0.56 0.69 69 73820 36 3 28 5 54
ASE_00018 0.75 0.67 0.84 90 80494 19 1 16 2 44
ASE_00020 0.49 0.43 0.56 54 73823 43 4 39 0 72
ASE_00021 0.62 0.51 0.75 82 104086 30 5 23 2 78
ASE_00035 0.62 0.57 0.68 67 70402 35 3 28 4 51
ASE_00037 0.56 0.49 0.64 54 59255 31 4 27 0 56
ASE_00038 0.57 0.53 0.61 54 53540 37 3 31 3 47
ASE_00040 0.69 0.62 0.75 83 78893 28 0 27 1 50
ASE_00041 0.72 0.67 0.78 72 57538 21 1 19 1 36
ASE_00042 0.50 0.41 0.61 60 90002 41 2 36 3 85
ASE_00044 0.83 0.77 0.89 81 54524 12 0 10 2 24
ASE_00064 0.76 0.67 0.86 60 45381 21 0 10 11 29
ASE_00068 0.76 0.71 0.82 60 37602 17 0 13 4 25
ASE_00074 0.82 0.78 0.87 93 67789 14 1 13 0 26
ASE_00075 0.75 0.64 0.87 104 108691 24 3 13 8 58
ASE_00077 0.61 0.55 0.67 47 45080 33 5 18 10 39
ASE_00078 0.81 0.77 0.84 64 42995 18 0 12 6 19
ASE_00080 0.52 0.48 0.57 59 71528 44 5 39 0 64
ASE_00081 0.80 0.75 0.86 73 49685 13 0 12 1 24
ASE_00082 0.58 0.53 0.63 62 70402 47 3 33 11 54
ASE_00083 0.82 0.74 0.91 81 62392 10 0 8 2 29
ASE_00084 0.60 0.55 0.67 54 53547 27 1 26 0 45
ASE_00087 0.47 0.40 0.57 57 88310 43 2 41 0 87
ASE_00090 0.52 0.46 0.60 46 55534 36 5 26 5 55
ASE_00092 0.69 0.63 0.76 71 63452 24 0 23 1 42
ASE_00099 0.81 0.76 0.86 91 64514 16 2 13 1 29
ASE_00104 0.82 0.76 0.89 90 64160 16 1 10 5 29
ASE_00105 0.53 0.49 0.58 54 64168 41 6 33 2 57
ASE_00107 0.64 0.57 0.73 72 73055 28 1 25 2 55
ASE_00115 0.72 0.61 0.84 62 54541 12 1 11 0 39
ASE_00118 0.55 0.49 0.62 50 60645 33 1 30 2 52
ASE_00119 0.55 0.50 0.61 54 62747 36 1 33 2 54
ASE_00123 0.55 0.51 0.60 43 38431 33 1 28 4 42
ASE_00126 0.70 0.70 0.71 57 40390 30 3 20 7 25
ASE_00128 0.74 0.62 0.87 62 53230 13 1 8 4 38
ASE_00129 0.69 0.63 0.75 70 62742 23 2 21 0 41
ASE_00131 0.48 0.42 0.54 36 39273 36 2 29 5 49
ASE_00134 0.71 0.67 0.74 64 50317 23 3 19 1 31
ASE_00135 0.54 0.49 0.60 53 63102 40 6 29 5 56
ASE_00136 0.83 0.78 0.89 72 48124 16 0 9 7 20
ASE_00137 0.52 0.48 0.56 47 48432 42 0 37 5 51
ASE_00138 0.79 0.73 0.87 59 40402 12 3 6 3 22
ASE_00140 0.46 0.38 0.55 48 70789 40 3 36 1 77
ASE_00142 0.72 0.67 0.78 82 67056 25 3 20 2 40
ASE_00146 0.64 0.54 0.76 67 70788 22 1 20 1 57
ASE_00153 0.38 0.37 0.39 27 57560 76 9 34 33 46
ASE_00163 0.69 0.67 0.71 62 53214 27 7 18 2 31
ASE_00165 0.54 0.49 0.60 49 52893 35 6 27 2 52
ASE_00170 0.83 0.77 0.90 72 48748 10 2 6 2 21
ASE_00171 0.88 0.80 0.96 75 48438 8 0 3 5 19
ASE_00172 0.66 0.58 0.76 61 58916 25 3 16 6 45
ASE_00174 0.53 0.45 0.63 49 60997 32 1 28 3 60
ASE_00175 0.63 0.55 0.73 59 59950 27 2 20 5 48
ASE_00179 0.76 0.69 0.84 58 44184 15 1 10 4 26
ASE_00180 0.77 0.70 0.85 70 51278 15 3 9 3 30
ASE_00181 0.67 0.63 0.71 67 57536 30 0 27 3 39
ASE_00182 0.48 0.40 0.57 55 84158 42 2 40 0 81
ASE_00183 0.70 0.63 0.77 71 61333 23 0 21 2 42
ASE_00184 0.76 0.68 0.85 69 54534 20 0 12 8 33
ASE_00185 0.42 0.38 0.47 48 73434 58 2 52 4 80
ASE_00190 0.46 0.37 0.57 33 45393 28 4 21 3 57
ASE_00197 0.42 0.36 0.50 52 89150 54 1 50 3 93
ASE_00198 0.63 0.58 0.69 59 52564 30 3 24 3 43
ASE_00203 0.56 0.52 0.61 50 46583 36 0 32 4 46
ASE_00212 0.66 0.59 0.74 88 93842 33 1 30 2 60
ASE_00214 0.83 0.79 0.87 81 56187 17 3 9 5 22
ASE_00215 0.18 0.15 0.23 15 48450 55 4 47 4 84
ASE_00216 0.71 0.67 0.74 55 39266 26 2 17 7 27
ASE_00217 0.50 0.46 0.55 41 40395 39 1 33 5 49
ASE_00221 0.65 0.56 0.74 66 64531 24 0 23 1 51
ASE_00228 0.69 0.67 0.72 58 46890 26 4 19 3 28
ASE_00229 0.60 0.57 0.63 50 42406 32 4 26 2 37
ASE_00231 0.44 0.40 0.50 38 47819 42 3 35 4 58
ASE_00232 0.81 0.81 0.81 68 38419 17 6 10 1 16
ASE_00234 0.68 0.60 0.76 78 75363 27 6 19 2 51
ASE_00238 0.50 0.45 0.55 51 64169 42 6 35 1 63
ASE_00241 0.78 0.71 0.86 62 43884 15 1 9 5 25
ASE_00242 0.72 0.66 0.80 74 60982 24 1 18 5 38
ASE_00254 0.48 0.46 0.50 38 36780 39 5 33 1 44
ASE_00257 0.70 0.64 0.78 62 50960 25 1 17 7 35
ASE_00263 0.46 0.41 0.52 49 70405 47 6 40 1 71
ASE_00267 0.75 0.68 0.82 60 45077 21 1 12 8 28
ASE_00270 0.56 0.49 0.64 63 72292 38 2 33 3 65
ASE_00274 0.59 0.51 0.67 53 55532 28 5 21 2 50
ASE_00277 0.79 0.75 0.83 68 48123 16 0 14 2 23
ASE_00279 0.78 0.73 0.82 74 53211 20 2 14 4 27
ASE_00280 0.72 0.66 0.78 65 51920 21 1 17 3 33
ASE_00281 0.80 0.73 0.89 64 44479 15 1 7 7 24
ASE_00282 0.48 0.42 0.56 53 77721 42 3 38 1 74
ASE_00283 0.73 0.67 0.80 72 61686 23 0 18 5 35
ASE_00284 0.65 0.59 0.71 64 58221 29 3 23 3 44
ASE_00285 0.58 0.51 0.67 62 68914 32 3 27 2 60
ASE_00286 0.82 0.74 0.91 68 46590 10 1 6 3 24
ASE_00287 0.62 0.56 0.68 58 54861 28 0 27 1 45
ASE_00292 0.74 0.64 0.84 89 81704 22 2 15 5 49
ASE_00294 0.75 0.63 0.89 108 114359 16 1 13 2 63
ASE_00296 0.64 0.54 0.76 78 91704 26 1 23 2 67
ASE_00297 0.62 0.53 0.72 52 52903 21 1 19 1 46
ASE_00298 0.48 0.43 0.53 49 67435 46 2 42 2 64
ASE_00328 0.76 0.67 0.87 75 72685 23 1 10 12 37
ASE_00332 0.45 0.37 0.55 51 81717 44 3 39 2 87
ASE_00340 0.58 0.54 0.63 46 45983 31 8 19 4 39
ASE_00342 0.82 0.76 0.88 87 62382 12 2 10 0 28
ASE_00353 0.65 0.62 0.69 66 57874 35 2 28 5 41
ASE_00361 0.58 0.49 0.69 62 75376 29 3 25 1 65
ASE_00362 0.74 0.65 0.86 59 48136 10 0 10 0 32
ASE_00363 0.81 0.73 0.90 69 51283 14 1 7 6 25
ASE_00364 0.63 0.56 0.71 59 54202 29 1 23 5 46
ASE_00366 0.62 0.57 0.67 56 58570 31 6 21 4 42
ASE_00367 0.57 0.53 0.61 46 42995 36 1 29 6 40
ASE_00369 0.82 0.74 0.92 79 55859 7 1 6 0 28
ASE_00370 0.86 0.81 0.92 68 41831 14 0 6 8 16
ASE_00372 0.67 0.59 0.77 59 51926 19 1 17 1 41
ASE_00374 0.81 0.73 0.90 64 44779 8 1 6 1 24
ASE_00376 0.66 0.61 0.71 64 56863 28 1 25 2 41
ASE_00377 0.61 0.55 0.69 59 57544 29 3 24 2 48
ASE_00379 0.54 0.48 0.61 43 45986 38 0 27 11 46
ASE_00382 0.86 0.81 0.92 68 41831 14 0 6 8 16
ASE_00383 0.79 0.72 0.85 76 54526 14 4 9 1 29
ASE_00384 0.70 0.65 0.75 60 48436 26 4 16 6 32
ASE_00386 0.65 0.60 0.70 58 50320 27 5 20 2 38
ASE_00387 0.67 0.63 0.70 66 55851 29 0 28 1 38
ASE_00388 0.51 0.47 0.56 42 45678 40 2 31 7 47
ASE_00390 0.85 0.80 0.89 68 42119 17 0 8 9 17
ASE_00393 0.70 0.63 0.77 59 47818 20 1 17 2 34
ASE_00394 0.80 0.72 0.88 67 46895 13 4 5 4 26
ASE_00395 0.73 0.69 0.77 58 41541 21 0 17 4 26
ASE_00396 0.72 0.66 0.79 55 41546 19 2 13 4 28
ASE_00397 0.74 0.69 0.79 72 54524 23 1 18 4 33
ASE_00398 0.68 0.62 0.76 64 55861 29 1 19 9 40
ASE_00400 0.74 0.69 0.80 73 57879 19 1 17 1 33
ASE_00401 0.52 0.44 0.63 55 76940 40 0 33 7 71
ASE_00402 0.76 0.69 0.84 59 42416 15 1 10 4 26
ASE_00403 0.66 0.58 0.76 62 55863 25 3 17 5 45
ASE_00404 0.78 0.73 0.83 62 42996 17 1 12 4 23
ASE_00406 0.82 0.73 0.91 69 48752 15 0 7 8 25
ASE_00411 0.57 0.53 0.62 47 49379 30 10 19 1 42
ASE_00412 0.56 0.50 0.62 53 58226 34 3 29 2 52
ASE_00413 0.60 0.57 0.64 46 44479 27 2 24 1 35
ASE_00415 0.60 0.57 0.63 59 54853 40 2 32 6 44
ASE_00416 0.69 0.59 0.80 75 77327 28 1 18 9 52
ASE_00419 0.75 0.68 0.83 70 54862 16 3 11 2 33
ASE_00422 0.65 0.63 0.67 59 46883 30 4 25 1 35
ASE_00423 0.84 0.77 0.92 84 56862 10 1 6 3 25
ASE_00428 0.57 0.54 0.60 68 76522 47 4 42 1 57
ASE_00430 0.79 0.76 0.82 74 46881 16 2 14 0 23
ASE_00437 0.67 0.60 0.75 81 79293 27 1 26 0 54
ASE_00441 0.66 0.57 0.77 64 64178 19 2 17 0 48
ASE_00448 0.63 0.59 0.67 66 64163 39 2 30 7 46
ASE_00451 0.68 0.60 0.77 75 70779 24 1 21 2 50
PDB_00571 0.85 0.76 0.95 19 3301 1 1 0 0 6
PDB_00828 0.88 0.78 1.00 21 2464 0 0 0 0 6
PDB_00829 0.86 0.75 1.00 18 2260 2 0 0 2 6
PDB_01020 0.86 0.74 1.00 17 2261 3 0 0 3 6
PDB_01073 0.86 0.74 1.00 25 4346 1 0 0 1 9
RFA_00599 0.71 0.71 0.71 79 101363 50 13 20 17 32
RFA_00601 0.58 0.54 0.61 62 99134 50 10 29 11 52
TMR_00017 0.59 0.56 0.62 57 67069 39 8 27 4 45
TMR_00018 0.59 0.54 0.65 50 64543 31 7 20 4 42
TMR_00038 0.73 0.66 0.79 73 71161 24 1 18 5 37
TMR_00042 0.61 0.57 0.65 56 62749 34 7 23 4 42
TMR_00046 0.65 0.63 0.67 60 62746 35 9 20 6 36
TMR_00048 0.59 0.55 0.63 52 64898 38 6 24 8 43
TMR_00080 0.51 0.46 0.56 44 70422 34 10 24 0 52
TMR_00082 0.65 0.59 0.71 57 67816 30 7 16 7 39
TMR_00123 0.64 0.59 0.68 60 66342 34 4 24 6 41
TMR_00137 0.33 0.28 0.38 25 61009 44 9 32 3 64
TMR_00142 0.62 0.64 0.61 65 70769 49 12 30 7 37
TMR_00207 0.40 0.35 0.45 36 72310 49 6 38 5 67
TMR_00257 0.68 0.61 0.76 60 67082 27 4 15 8 38
TMR_00271 0.64 0.56 0.74 51 64192 20 6 12 2 40
TMR_00366 0.64 0.60 0.67 60 67807 40 12 17 11 40
TMR_00378 0.67 0.63 0.71 61 67810 38 5 20 13 36
TMR_00399 0.48 0.45 0.52 42 64899 46 9 30 7 52
TMR_00404 0.59 0.59 0.60 54 67438 49 12 24 13 38
TMR_00427 0.53 0.41 0.69 40 67470 22 7 11 4 57
TMR_00443 0.67 0.59 0.77 61 67082 22 4 14 4 43
TMR_00451 0.52 0.45 0.60 40 63479 31 7 20 4 49
TMR_00458 0.70 0.63 0.77 59 63469 21 4 14 3 34
TMR_00469 0.75 0.73 0.78 73 64526 30 7 14 9 27
TMR_00472 0.76 0.73 0.80 71 64531 23 7 11 5 26
TMR_00519 0.60 0.57 0.64 54 63106 34 12 18 4 41
TMR_00520 0.67 0.62 0.73 61 63106 31 4 19 8 38
TMR_00522 0.53 0.47 0.60 46 63113 36 9 22 5 51
TMR_00528 0.51 0.45 0.58 44 63114 37 10 22 5 53
TMR_00568 0.62 0.59 0.65 58 60637 40 8 23 9 41
TMR_00571 0.69 0.65 0.73 64 60638 34 10 14 10 35
TMR_00580 0.62 0.61 0.63 61 60629 46 10 26 10 39
TMR_00584 0.65 0.61 0.69 59 60989 36 6 21 9 38
TMR_00586 0.60 0.59 0.61 57 60982 43 11 25 7 40
TMR_00616 0.65 0.63 0.68 62 67070 35 7 22 6 37
TMR_00699 0.69 0.60 0.80 61 67085 16 2 13 1 41
TMR_00702 0.63 0.54 0.73 54 67087 26 7 13 6 46

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Performance of IPknot - scored lower in this pairwise comparison

1. Total counts & total scores for IPknot

Total Base Pair Counts
Total TP 11566
Total TN 11496494
Total FP 4818
Total FP CONTRA 642
Total FP INCONS 3567
Total FP COMP 609
Total FN 8519
Total Scores
MCC 0.649
Average MCC ± 95% Confidence Intervals 0.652 ± 0.018
Sensitivity 0.576
Positive Predictive Value 0.733
Nr of predictions 196

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2. Individual counts for IPknot [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00005 0.59 0.51 0.69 60 57883 30 0 27 3 57
ASE_00006 0.60 0.52 0.70 48 47517 22 3 18 1 45
ASE_00007 0.63 0.55 0.72 60 59602 27 0 23 4 50
ASE_00012 0.66 0.56 0.78 69 73832 22 5 14 3 54
ASE_00018 0.70 0.64 0.77 86 80489 27 0 26 1 48
ASE_00020 0.67 0.58 0.77 73 73825 22 2 20 0 53
ASE_00021 0.70 0.57 0.85 91 104089 21 3 13 5 69
ASE_00035 0.44 0.30 0.66 35 70447 21 4 14 3 83
ASE_00037 0.47 0.39 0.57 43 59265 34 0 32 2 67
ASE_00038 0.59 0.53 0.66 54 53546 28 4 24 0 47
ASE_00040 0.51 0.42 0.62 56 78913 38 0 34 4 77
ASE_00041 0.69 0.50 0.96 54 57574 4 0 2 2 54
ASE_00042 0.60 0.51 0.70 74 89994 33 1 31 1 71
ASE_00044 0.70 0.70 0.72 73 54513 34 3 26 5 32
ASE_00064 0.68 0.60 0.77 53 45382 22 3 13 6 36
ASE_00068 0.75 0.60 0.94 51 37621 3 0 3 0 34
ASE_00074 0.49 0.45 0.54 53 67798 45 4 41 0 66
ASE_00075 0.71 0.61 0.83 99 108691 25 2 19 4 63
ASE_00077 0.68 0.53 0.87 46 45097 12 2 5 5 40
ASE_00078 0.70 0.57 0.87 47 43017 7 1 6 0 36
ASE_00080 0.41 0.36 0.47 44 71537 54 5 45 4 79
ASE_00081 0.79 0.71 0.88 69 49692 10 1 8 1 28
ASE_00082 0.83 0.74 0.93 86 70408 18 0 6 12 30
ASE_00083 0.77 0.72 0.82 79 62385 22 0 17 5 31
ASE_00084 0.83 0.74 0.94 73 53550 8 1 4 3 26
ASE_00087 0.74 0.63 0.87 90 88306 14 2 12 0 54
ASE_00090 0.66 0.58 0.75 59 55532 20 1 19 0 42
ASE_00092 0.85 0.78 0.93 88 63451 9 1 6 2 25
ASE_00099 0.80 0.70 0.92 84 64529 7 0 7 0 36
ASE_00104 0.75 0.66 0.84 79 64167 15 2 13 0 40
ASE_00105 0.48 0.41 0.56 46 64179 39 6 30 3 65
ASE_00107 0.73 0.66 0.82 84 73050 19 1 18 0 43
ASE_00115 0.74 0.68 0.81 69 54530 23 4 12 7 32
ASE_00118 0.40 0.37 0.44 38 60639 50 3 46 1 64
ASE_00119 0.85 0.81 0.91 87 62739 9 1 8 0 21
ASE_00123 0.52 0.49 0.55 42 38427 38 2 32 4 43
ASE_00126 0.65 0.59 0.72 48 40403 25 1 18 6 34
ASE_00128 0.78 0.65 0.94 65 53232 7 0 4 3 35
ASE_00129 0.70 0.67 0.74 74 62735 27 5 21 1 37
ASE_00131 0.80 0.66 0.98 56 39283 5 0 1 4 29
ASE_00134 0.51 0.47 0.55 45 50321 37 4 33 0 50
ASE_00135 0.67 0.58 0.79 63 63110 22 1 16 5 46
ASE_00136 0.61 0.52 0.72 48 48138 28 1 18 9 44
ASE_00137 0.75 0.68 0.82 67 48434 15 0 15 0 31
ASE_00138 0.58 0.48 0.70 39 40414 17 1 16 0 42
ASE_00140 0.72 0.61 0.85 76 70787 14 3 10 1 49
ASE_00142 0.73 0.65 0.81 79 67064 19 4 14 1 43
ASE_00146 0.55 0.43 0.72 53 70802 22 5 16 1 71
ASE_00153 0.52 0.51 0.54 37 57562 60 6 25 29 36
ASE_00163 0.39 0.35 0.43 33 53224 53 4 40 9 60
ASE_00165 0.65 0.55 0.77 56 52902 18 4 13 1 45
ASE_00170 0.63 0.55 0.73 51 48758 20 3 16 1 42
ASE_00171 0.71 0.67 0.76 63 48433 20 4 16 0 31
ASE_00172 0.81 0.71 0.94 75 58916 5 1 4 0 31
ASE_00174 0.63 0.60 0.66 65 60977 33 8 25 0 44
ASE_00175 0.62 0.55 0.70 59 59947 26 2 23 1 48
ASE_00179 0.65 0.56 0.75 47 44190 18 2 14 2 37
ASE_00180 0.69 0.56 0.85 56 51294 10 2 8 0 44
ASE_00181 0.60 0.53 0.67 56 57547 31 0 27 4 50
ASE_00182 0.57 0.53 0.62 72 84139 44 3 41 0 64
ASE_00183 0.74 0.68 0.81 77 61330 18 0 18 0 36
ASE_00184 0.71 0.70 0.73 71 54518 26 4 22 0 31
ASE_00185 0.79 0.69 0.92 88 73440 10 0 8 2 40
ASE_00190 0.75 0.58 0.98 52 45398 3 0 1 2 38
ASE_00197 0.67 0.57 0.78 83 89147 28 1 22 5 62
ASE_00198 0.72 0.63 0.83 64 52573 13 2 11 0 38
ASE_00203 0.77 0.69 0.87 66 46589 10 1 9 0 30
ASE_00212 0.73 0.68 0.79 101 93833 31 3 24 4 47
ASE_00214 0.80 0.78 0.83 80 56184 23 3 13 7 23
ASE_00215 0.48 0.41 0.56 41 48443 32 1 31 0 58
ASE_00216 0.66 0.62 0.70 51 39267 22 3 19 0 31
ASE_00217 0.34 0.29 0.41 26 40406 39 7 31 1 64
ASE_00221 0.61 0.46 0.82 54 64554 12 1 11 0 63
ASE_00228 0.78 0.74 0.82 64 46893 16 6 8 2 22
ASE_00229 0.73 0.63 0.83 55 42420 12 3 8 1 32
ASE_00231 0.74 0.66 0.83 63 47819 13 3 10 0 33
ASE_00232 0.80 0.77 0.82 65 38424 14 7 7 0 19
ASE_00234 0.58 0.49 0.70 63 75376 31 2 25 4 66
ASE_00238 0.64 0.54 0.75 62 64178 22 1 20 1 52
ASE_00241 0.72 0.60 0.87 52 43896 8 1 7 0 35
ASE_00242 0.73 0.59 0.92 66 61003 6 1 5 0 46
ASE_00254 0.76 0.68 0.85 56 36790 15 3 7 5 26
ASE_00257 0.76 0.63 0.91 61 50973 6 1 5 0 36
ASE_00263 0.70 0.62 0.80 74 70407 19 3 16 0 46
ASE_00267 0.54 0.42 0.70 37 45097 22 0 16 6 51
ASE_00270 0.76 0.73 0.79 93 72273 26 1 23 2 35
ASE_00274 0.64 0.55 0.75 57 55535 19 5 14 0 46
ASE_00277 0.59 0.53 0.66 48 48132 25 4 21 0 43
ASE_00279 0.73 0.62 0.86 63 53228 10 3 7 0 38
ASE_00280 0.70 0.61 0.81 60 51929 15 1 13 1 38
ASE_00281 0.82 0.74 0.90 65 44479 13 0 7 6 23
ASE_00282 0.55 0.51 0.60 65 77706 44 6 38 0 62
ASE_00283 0.77 0.72 0.83 77 61683 16 5 11 0 30
ASE_00284 0.69 0.68 0.72 73 58209 34 5 24 5 35
ASE_00285 0.80 0.75 0.86 91 68900 23 3 12 8 31
ASE_00286 0.67 0.57 0.80 52 46600 17 1 12 4 40
ASE_00287 0.72 0.69 0.76 71 54853 23 2 20 1 32
ASE_00292 0.68 0.60 0.76 83 81701 27 2 24 1 55
ASE_00294 0.78 0.68 0.90 117 114351 14 1 12 1 54
ASE_00296 0.48 0.43 0.53 63 91688 56 5 50 1 82
ASE_00297 0.68 0.62 0.74 61 52893 21 3 18 0 37
ASE_00298 0.57 0.51 0.64 58 67438 34 1 31 2 55
ASE_00328 0.70 0.60 0.83 67 72690 20 4 10 6 45
ASE_00332 0.55 0.50 0.60 69 81695 47 2 44 1 69
ASE_00340 0.76 0.75 0.77 64 45973 25 8 11 6 21
ASE_00342 0.75 0.68 0.83 78 62387 17 1 15 1 37
ASE_00353 0.57 0.51 0.63 55 57882 35 4 29 2 52
ASE_00361 0.53 0.47 0.59 60 75364 45 9 33 3 67
ASE_00362 0.66 0.59 0.74 54 48132 20 2 17 1 37
ASE_00363 0.76 0.64 0.91 60 51294 7 0 6 1 34
ASE_00364 0.63 0.56 0.70 59 54201 25 3 22 0 46
ASE_00366 0.54 0.51 0.58 50 58567 36 5 31 0 48
ASE_00367 0.62 0.55 0.71 47 43005 23 5 14 4 39
ASE_00369 0.73 0.71 0.75 76 55843 27 0 26 1 31
ASE_00370 0.49 0.43 0.55 36 41840 29 1 28 0 48
ASE_00372 0.74 0.68 0.80 68 51918 20 3 14 3 32
ASE_00374 0.64 0.61 0.68 54 44770 26 5 21 0 34
ASE_00376 0.62 0.57 0.68 60 56865 30 5 23 2 45
ASE_00377 0.77 0.74 0.81 79 57532 24 3 16 5 28
ASE_00379 0.70 0.62 0.79 55 45986 16 5 10 1 34
ASE_00382 0.69 0.58 0.82 49 41845 14 5 6 3 35
ASE_00383 0.71 0.64 0.80 67 54531 19 5 12 2 38
ASE_00384 0.73 0.71 0.76 65 48430 25 1 20 4 27
ASE_00386 0.65 0.60 0.70 58 50320 30 1 24 5 38
ASE_00387 0.75 0.65 0.86 68 55866 13 1 10 2 36
ASE_00388 0.74 0.61 0.90 54 45693 7 0 6 1 35
ASE_00390 0.77 0.71 0.85 60 42124 18 0 11 7 25
ASE_00393 0.72 0.65 0.81 60 47821 15 0 14 1 33
ASE_00394 0.80 0.76 0.85 71 46887 14 3 10 1 22
ASE_00395 0.77 0.73 0.81 61 41541 14 2 12 0 23
ASE_00396 0.68 0.61 0.76 51 41549 18 5 11 2 32
ASE_00397 0.81 0.72 0.92 76 54532 7 2 5 0 29
ASE_00398 0.65 0.59 0.72 61 55860 25 1 23 1 43
ASE_00400 0.74 0.65 0.83 69 57887 15 1 13 1 37
ASE_00401 0.64 0.60 0.68 75 76918 35 5 30 0 51
ASE_00402 0.68 0.60 0.77 51 42420 15 4 11 0 34
ASE_00403 0.57 0.47 0.69 50 55873 22 0 22 0 57
ASE_00404 0.58 0.51 0.66 43 43006 22 1 21 0 42
ASE_00406 0.74 0.64 0.87 60 48759 11 0 9 2 34
ASE_00411 0.59 0.46 0.75 41 49400 15 5 9 1 48
ASE_00412 0.56 0.47 0.67 49 58238 24 7 17 0 56
ASE_00413 0.47 0.46 0.49 37 44475 42 5 34 3 44
ASE_00415 0.70 0.65 0.74 67 54856 28 1 22 5 36
ASE_00416 0.71 0.60 0.84 76 77330 20 0 15 5 51
ASE_00419 0.78 0.74 0.83 76 54854 17 3 13 1 27
ASE_00422 0.69 0.65 0.74 61 46889 26 6 15 5 33
ASE_00423 0.65 0.64 0.66 70 56847 36 6 30 0 39
ASE_00428 0.65 0.59 0.72 74 76533 33 2 27 4 51
ASE_00430 0.76 0.68 0.85 66 46893 17 3 9 5 31
ASE_00437 0.55 0.41 0.74 56 79325 20 0 20 0 79
ASE_00441 0.79 0.72 0.86 81 64167 15 2 11 2 31
ASE_00448 0.53 0.42 0.66 47 64190 30 4 20 6 65
ASE_00451 0.75 0.66 0.85 82 70780 14 2 12 0 43
PDB_00571 0.79 0.76 0.83 19 3298 4 2 2 0 6
PDB_00828 0.90 0.81 1.00 22 2463 0 0 0 0 5
PDB_00829 0.86 0.75 1.00 18 2260 0 0 0 0 6
PDB_01020 0.86 0.74 1.00 17 2261 1 0 0 1 6
PDB_01073 0.80 0.65 1.00 22 4349 1 0 0 1 12
RFA_00599 0.75 0.73 0.77 81 101370 40 8 16 16 30
RFA_00601 0.45 0.46 0.43 53 99113 82 25 44 13 61
TMR_00017 0.70 0.55 0.89 56 67098 11 0 7 4 46
TMR_00018 0.40 0.33 0.48 30 64558 36 6 26 4 62
TMR_00038 0.23 0.21 0.25 23 71161 75 9 60 6 87
TMR_00042 0.38 0.34 0.44 33 62760 45 2 40 3 65
TMR_00046 0.50 0.48 0.53 46 62748 45 5 36 4 50
TMR_00048 0.49 0.48 0.50 46 64888 54 6 40 8 49
TMR_00080 0.65 0.60 0.70 58 70417 26 6 19 1 38
TMR_00082 0.78 0.77 0.80 74 67803 24 8 11 5 22
TMR_00123 0.85 0.77 0.93 78 66346 11 0 6 5 23
TMR_00137 0.34 0.28 0.40 25 61013 45 6 31 8 64
TMR_00142 0.65 0.63 0.67 64 70780 39 9 23 7 38
TMR_00207 0.47 0.40 0.56 41 72317 36 3 29 4 62
TMR_00257 0.63 0.50 0.80 49 67100 18 2 10 6 49
TMR_00271 0.62 0.56 0.68 51 64186 35 6 18 11 40
TMR_00366 0.63 0.53 0.76 53 67826 28 5 12 11 47
TMR_00378 0.32 0.28 0.38 27 67824 56 14 31 11 70
TMR_00399 0.41 0.33 0.51 31 64919 37 11 19 7 63
TMR_00404 0.60 0.55 0.65 51 67450 38 6 21 11 41
TMR_00427 0.60 0.52 0.69 50 67456 27 10 12 5 47
TMR_00443 0.65 0.55 0.77 57 67087 24 8 9 7 47
TMR_00451 0.26 0.26 0.27 23 63461 66 16 46 4 66
TMR_00458 0.48 0.40 0.59 37 63483 33 6 20 7 56
TMR_00469 0.52 0.51 0.54 51 64525 48 16 28 4 49
TMR_00472 0.55 0.44 0.67 43 64556 26 6 15 5 54
TMR_00519 0.44 0.35 0.57 33 63132 35 7 18 10 62
TMR_00520 0.52 0.46 0.58 46 63110 43 7 27 9 53
TMR_00522 0.53 0.47 0.60 46 63113 39 5 26 8 51
TMR_00528 0.43 0.40 0.46 39 63106 55 11 34 10 58
TMR_00568 0.66 0.53 0.84 52 60664 16 0 10 6 47
TMR_00571 0.68 0.60 0.79 59 60651 24 2 14 8 40
TMR_00580 0.74 0.71 0.77 71 60634 29 2 19 8 29
TMR_00584 0.61 0.59 0.64 57 60986 36 3 29 4 40
TMR_00586 0.58 0.53 0.65 51 60996 34 6 22 6 46
TMR_00616 0.53 0.45 0.62 45 67088 33 6 22 5 54
TMR_00699 0.80 0.72 0.89 73 67079 13 3 6 4 29
TMR_00702 0.58 0.48 0.70 48 67092 26 5 16 5 52

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.