Table of contents:
- Overview
- Performance Plots
- Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
- Performance of Murlet(seed)
- scored lower in this pairwise comparison
- Compile and download dataset for PETfold_pre2.0(seed) & Murlet(seed) [.zip] - may take several seconds...
Overview
| Metric |
PETfold_pre2.0(seed) |
|
Murlet(seed) |
| MCC |
0.791 |
>
|
0.584 |
| Average MCC ± 95% Confidence Intervals |
0.671
±
0.054
|
>
|
0.476
±
0.098
|
| Sensitivity |
0.737 |
>
|
0.492 |
| Positive Predictive Value |
0.849 |
>
|
0.694 |
| Total TP |
530 |
>
|
354 |
| Total TN |
1014995 |
<
|
1015109 |
| Total FP |
132 |
<
|
180 |
| Total FP CONTRA |
31 |
>
|
6 |
| Total FP INCONS |
63 |
<
|
150 |
| Total FP COMP |
38 |
>
|
24 |
| Total FN |
189 |
<
|
365 |
| P-value |
1.26497248087e-08 |
Performance plots
-
Comparison of performance of PETfold_pre2.0(seed) and Murlet(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Murlet(seed)).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Murlet(seed)).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Murlet(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Murlet(seed)).
Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
1. Total counts & total scores for PETfold_pre2.0(seed)
| Total Base Pair Counts |
| Total TP |
530 |
| Total TN |
1014995 |
| Total FP |
132 |
| Total FP CONTRA |
31 |
| Total FP INCONS |
63 |
| Total FP COMP |
38 |
| Total FN |
189 |
| Total Scores |
| MCC |
0.791 |
| Average MCC ± 95% Confidence Intervals |
0.671
±
0.054
|
| Sensitivity |
0.737 |
| Positive Predictive Value |
0.849 |
| Nr of predictions |
14 |
Performance of Murlet(seed)
- scored lower in this pairwise comparison
1. Total counts & total scores for Murlet(seed)
| Total Base Pair Counts |
| Total TP |
354 |
| Total TN |
1015109 |
| Total FP |
180 |
| Total FP CONTRA |
6 |
| Total FP INCONS |
150 |
| Total FP COMP |
24 |
| Total FN |
365 |
| Total Scores |
| MCC |
0.584 |
| Average MCC ± 95% Confidence Intervals |
0.476
±
0.098
|
| Sensitivity |
0.492 |
| Positive Predictive Value |
0.694 |
| Nr of predictions |
14 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based
on the paper by Gardener & Giegerich, 2004.
|