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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of CentroidHomfold‑LAST - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & CentroidHomfold‑LAST [.zip] - may take several seconds...


Overview

Metric PPfold(20) CentroidHomfold‑LAST
MCC 0.735 > 0.703
Average MCC ± 95% Confidence Intervals 0.737 ± 0.013 > 0.704 ± 0.013
Sensitivity 0.635 > 0.551
Positive Predictive Value 0.851 < 0.898
Total TP 13225 > 11475
Total TN 11998571 < 12001330
Total FP 3193 > 1780
Total FP CONTRA 578 > 225
Total FP INCONS 1740 > 1084
Total FP COMP 875 > 471
Total FN 7595 < 9345
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of PPfold(20) and CentroidHomfold-LAST. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and CentroidHomfold‑LAST).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for PPfold(20) and CentroidHomfold‑LAST).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and CentroidHomfold-LAST. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and CentroidHomfold‑LAST).

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Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 13225
Total TN 11998571
Total FP 3193
Total FP CONTRA 578
Total FP INCONS 1740
Total FP COMP 875
Total FN 7595
Total Scores
MCC 0.735
Average MCC ± 95% Confidence Intervals 0.737 ± 0.013
Sensitivity 0.635
Positive Predictive Value 0.851
Nr of predictions 202

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.67 0.57 0.80 55 47826 17 1 13 3 42
ASE_00005 0.75 0.64 0.88 75 57885 13 3 7 3 42
ASE_00006 0.69 0.60 0.80 56 47516 16 1 13 2 37
ASE_00007 0.85 0.81 0.89 89 59585 15 2 9 4 21
ASE_00012 0.74 0.67 0.82 83 73819 24 4 14 6 40
ASE_00018 0.77 0.66 0.90 89 80502 14 3 7 4 45
ASE_00020 0.66 0.52 0.84 66 73841 19 6 7 6 60
ASE_00021 0.55 0.44 0.69 70 104095 36 5 26 5 90
ASE_00022 0.78 0.69 0.87 86 82929 22 1 12 9 38
ASE_00028 0.75 0.64 0.87 81 84573 20 1 11 8 45
ASE_00035 0.80 0.73 0.88 86 70402 19 1 11 7 32
ASE_00037 0.86 0.81 0.92 89 59243 13 1 7 5 21
ASE_00040 0.81 0.71 0.92 95 78900 10 3 5 2 38
ASE_00041 0.83 0.81 0.85 88 57527 18 2 13 3 20
ASE_00042 0.67 0.57 0.80 82 89998 23 2 18 3 63
ASE_00044 0.89 0.86 0.92 90 54517 10 2 6 2 15
ASE_00064 0.80 0.73 0.87 65 45376 15 1 9 5 24
ASE_00068 0.64 0.54 0.75 46 37614 17 5 10 2 39
ASE_00074 0.85 0.78 0.93 93 67796 12 1 6 5 26
ASE_00075 0.57 0.44 0.72 72 108711 35 5 23 7 90
ASE_00077 0.85 0.83 0.88 71 45069 14 5 5 4 15
ASE_00078 0.91 0.87 0.95 72 42995 11 1 3 7 11
ASE_00080 0.44 0.35 0.57 43 71555 36 2 31 3 80
ASE_00081 0.82 0.73 0.92 71 49693 9 2 4 3 26
ASE_00082 0.65 0.52 0.81 60 70426 22 1 13 8 56
ASE_00083 0.74 0.62 0.89 68 62405 13 3 5 5 42
ASE_00084 0.74 0.65 0.84 64 53552 16 2 10 4 35
ASE_00090 0.78 0.67 0.91 68 55536 11 2 5 4 33
ASE_00092 0.65 0.53 0.79 60 63470 21 3 13 5 53
ASE_00099 0.85 0.78 0.93 93 64520 11 2 5 4 27
ASE_00104 0.83 0.76 0.91 91 64161 15 1 8 6 28
ASE_00105 0.59 0.50 0.70 56 64181 29 6 18 5 55
ASE_00107 0.83 0.75 0.92 95 73050 11 2 6 3 32
ASE_00115 0.78 0.68 0.88 69 54537 12 2 7 3 32
ASE_00118 0.70 0.60 0.82 61 60652 17 2 11 4 41
ASE_00119 0.70 0.54 0.92 58 62772 8 2 3 3 50
ASE_00123 0.69 0.59 0.82 50 38442 14 3 8 3 35
ASE_00125 0.72 0.60 0.87 53 39279 14 2 6 6 35
ASE_00126 0.85 0.79 0.90 65 40398 13 2 5 6 17
ASE_00128 0.80 0.70 0.92 70 53225 10 2 4 4 30
ASE_00129 0.77 0.65 0.92 72 62757 9 3 3 3 39
ASE_00131 0.75 0.62 0.90 53 39281 12 2 4 6 32
ASE_00134 0.75 0.68 0.83 65 50325 16 1 12 3 30
ASE_00135 0.63 0.54 0.74 59 63110 24 3 18 3 50
ASE_00136 0.79 0.72 0.88 66 48130 12 2 7 3 26
ASE_00137 0.80 0.66 0.97 65 48449 7 1 1 5 33
ASE_00138 0.84 0.78 0.91 63 40401 10 2 4 4 18
ASE_00140 0.69 0.55 0.86 69 70796 17 7 4 6 56
ASE_00142 0.83 0.74 0.93 90 67064 13 2 5 6 32
ASE_00146 0.81 0.71 0.92 88 70780 13 1 7 5 36
ASE_00153 0.43 0.37 0.50 27 57576 32 4 23 5 46
ASE_00163 0.83 0.76 0.90 71 53222 12 1 7 4 22
ASE_00165 0.79 0.66 0.94 67 52904 10 2 2 6 34
ASE_00170 0.73 0.66 0.80 61 48752 20 2 13 5 32
ASE_00171 0.82 0.74 0.91 70 48439 11 3 4 4 24
ASE_00172 0.77 0.65 0.91 69 58920 10 3 4 3 37
ASE_00174 0.66 0.54 0.80 59 61001 18 3 12 3 50
ASE_00175 0.73 0.64 0.85 68 59951 17 3 9 5 39
ASE_00179 0.83 0.80 0.87 67 44176 15 5 5 5 17
ASE_00180 0.78 0.69 0.88 69 51282 12 3 6 3 31
ASE_00181 0.70 0.59 0.83 63 57554 18 4 9 5 43
ASE_00182 0.69 0.53 0.90 72 84175 11 3 5 3 64
ASE_00183 0.76 0.65 0.90 73 61344 12 2 6 4 40
ASE_00184 0.77 0.68 0.87 69 54536 13 2 8 3 33
ASE_00185 0.68 0.52 0.90 66 73463 12 3 4 5 62
ASE_00186 0.69 0.60 0.80 79 78904 24 3 17 4 53
ASE_00190 0.75 0.64 0.87 58 45384 12 1 8 3 32
ASE_00197 0.67 0.55 0.81 80 89154 24 2 17 5 65
ASE_00198 0.80 0.70 0.92 71 52573 9 1 5 3 31
ASE_00203 0.80 0.72 0.90 69 46588 13 3 5 5 27
ASE_00212 0.66 0.53 0.83 78 93867 20 2 14 4 70
ASE_00214 0.77 0.66 0.91 68 56205 11 3 4 4 35
ASE_00215 0.62 0.46 0.82 46 48460 13 2 8 3 53
ASE_00216 0.91 0.84 0.99 69 39270 5 1 0 4 13
ASE_00217 0.83 0.77 0.91 69 40394 11 2 5 4 21
ASE_00221 0.85 0.78 0.93 91 64522 10 1 6 3 26
ASE_00228 0.75 0.69 0.83 59 46900 16 2 10 4 27
ASE_00229 0.88 0.79 0.97 69 42415 5 2 0 3 18
ASE_00231 0.67 0.57 0.77 55 47824 22 1 15 6 41
ASE_00232 0.89 0.82 0.97 69 38432 6 1 1 4 15
ASE_00234 0.66 0.53 0.83 68 75384 20 6 8 6 61
ASE_00238 0.67 0.56 0.80 64 64181 22 5 11 6 50
ASE_00241 0.83 0.78 0.87 68 43878 14 1 9 4 19
ASE_00242 0.86 0.82 0.90 92 60973 15 1 9 5 20
ASE_00248 0.86 0.81 0.91 92 62380 13 1 8 4 22
ASE_00254 0.85 0.77 0.94 63 36789 8 2 2 4 19
ASE_00255 0.62 0.55 0.71 72 74589 32 4 26 2 58
ASE_00257 0.73 0.65 0.82 63 50963 17 4 10 3 34
ASE_00263 0.70 0.57 0.87 68 70422 14 3 7 4 52
ASE_00267 0.84 0.77 0.91 68 45075 13 2 5 6 20
ASE_00270 0.58 0.43 0.79 55 72320 19 2 13 4 73
ASE_00274 0.68 0.60 0.78 62 55531 21 5 13 3 41
ASE_00279 0.79 0.69 0.90 70 53223 11 3 5 3 31
ASE_00280 0.74 0.66 0.82 65 51924 17 3 11 3 33
ASE_00281 0.81 0.75 0.87 66 44475 12 3 7 2 22
ASE_00282 0.70 0.54 0.90 69 77738 12 2 6 4 58
ASE_00283 0.73 0.63 0.86 67 61698 14 2 9 3 40
ASE_00284 0.77 0.66 0.91 71 58233 11 4 3 4 37
ASE_00285 0.70 0.55 0.91 67 68932 11 2 5 4 55
ASE_00286 0.81 0.73 0.89 67 46590 12 2 6 4 25
ASE_00287 0.69 0.60 0.79 62 54868 20 1 15 4 41
ASE_00292 0.72 0.62 0.83 86 81707 20 2 15 3 52
ASE_00294 0.72 0.57 0.92 97 114375 13 2 7 4 74
ASE_00296 0.72 0.61 0.86 88 91704 18 4 10 4 57
ASE_00297 0.68 0.58 0.79 57 52903 19 4 11 4 41
ASE_00298 0.72 0.61 0.85 69 67447 15 3 9 3 44
ASE_00318 0.75 0.66 0.85 78 80108 21 1 13 7 40
ASE_00328 0.81 0.75 0.88 84 72675 19 1 11 7 28
ASE_00332 0.78 0.67 0.91 92 81709 12 3 6 3 46
ASE_00335 0.77 0.70 0.85 81 75371 25 1 13 11 35
ASE_00340 0.75 0.67 0.85 57 45989 17 1 9 7 28
ASE_00342 0.89 0.83 0.96 95 62382 9 1 3 5 20
ASE_00353 0.75 0.64 0.88 68 57893 14 2 7 5 39
ASE_00361 0.69 0.53 0.89 67 75391 13 3 5 5 60
ASE_00362 0.80 0.71 0.89 65 48132 14 2 6 6 26
ASE_00363 0.76 0.68 0.84 64 51284 17 2 10 5 30
ASE_00364 0.76 0.66 0.87 69 54206 15 3 7 5 36
ASE_00366 0.76 0.67 0.87 66 58577 13 3 7 3 32
ASE_00367 0.85 0.79 0.91 68 42996 11 2 5 4 18
ASE_00369 0.79 0.69 0.90 74 55863 13 1 7 5 33
ASE_00372 0.76 0.65 0.88 65 51929 15 1 8 6 35
ASE_00374 0.86 0.80 0.93 70 44775 8 2 3 3 18
ASE_00376 0.73 0.63 0.85 66 56875 15 1 11 3 39
ASE_00377 0.76 0.65 0.88 70 57550 13 3 7 3 37
ASE_00382 0.83 0.80 0.87 67 41828 16 2 8 6 17
ASE_00383 0.77 0.66 0.90 69 54538 13 1 7 5 36
ASE_00384 0.81 0.74 0.89 68 48440 13 2 6 5 24
ASE_00386 0.79 0.71 0.88 68 50326 12 2 7 3 28
ASE_00387 0.71 0.62 0.83 64 55868 17 2 11 4 40
ASE_00388 0.80 0.73 0.87 65 45678 16 1 9 6 24
ASE_00390 0.85 0.80 0.89 68 42119 11 2 6 3 17
ASE_00393 0.74 0.68 0.82 63 47818 19 1 13 5 30
ASE_00394 0.83 0.74 0.92 69 46896 10 2 4 4 24
ASE_00395 0.83 0.79 0.87 66 41540 13 2 8 3 18
ASE_00396 0.86 0.83 0.90 69 41539 12 3 5 4 14
ASE_00397 0.75 0.64 0.88 67 54539 15 3 6 6 38
ASE_00398 0.74 0.63 0.87 65 55870 13 1 9 3 39
ASE_00400 0.79 0.67 0.92 71 57893 12 1 5 6 35
ASE_00401 0.67 0.51 0.88 64 76955 13 2 7 4 62
ASE_00402 0.85 0.80 0.89 68 42410 12 2 6 4 17
ASE_00403 0.79 0.67 0.92 72 55867 12 1 5 6 35
ASE_00404 0.85 0.80 0.89 68 42995 14 4 4 6 17
ASE_00406 0.79 0.72 0.86 68 48749 14 2 9 3 26
ASE_00411 0.70 0.67 0.72 60 49372 27 7 16 4 29
ASE_00412 0.62 0.54 0.71 57 58231 28 5 18 5 48
ASE_00413 0.76 0.73 0.79 59 44476 23 4 12 7 22
ASE_00416 0.74 0.66 0.82 84 77319 23 4 14 5 43
ASE_00419 0.72 0.61 0.84 63 54871 16 5 7 4 40
ASE_00422 0.82 0.73 0.91 69 46895 13 1 6 6 25
ASE_00423 0.75 0.71 0.80 77 56857 23 3 16 4 32
ASE_00428 0.75 0.68 0.83 85 76533 21 4 14 3 40
ASE_00430 0.75 0.66 0.85 64 46896 14 1 10 3 33
ASE_00437 0.58 0.50 0.69 67 79304 33 1 29 3 68
ASE_00441 0.70 0.57 0.86 64 64187 13 3 7 3 48
ASE_00448 0.83 0.79 0.87 88 64160 15 3 10 2 24
ASE_00451 0.81 0.73 0.91 91 70776 12 1 8 3 34
PDB_00571 0.87 0.80 0.95 20 3300 1 1 0 0 5
PDB_00828 0.84 0.70 1.00 19 2466 2 0 0 2 8
PDB_00829 0.86 0.75 1.00 18 2260 2 0 0 2 6
PDB_01020 0.86 0.74 1.00 17 2261 3 0 0 3 6
PDB_01073 0.79 0.71 0.89 24 4344 4 2 1 1 10
RFA_00599 0.86 0.80 0.93 89 101379 16 3 4 9 22
RFA_00601 0.77 0.68 0.89 77 99148 20 1 9 10 37
TMR_00017 0.71 0.55 0.92 56 67100 8 1 4 3 46
TMR_00018 0.63 0.52 0.76 48 64557 21 6 9 6 44
TMR_00038 0.61 0.52 0.73 57 71175 26 5 16 5 53
TMR_00042 0.62 0.49 0.79 48 62774 13 4 9 0 50
TMR_00046 0.46 0.36 0.58 35 62775 26 4 21 1 61
TMR_00048 0.63 0.52 0.77 49 64916 16 7 8 1 46
TMR_00080 0.64 0.51 0.80 49 70439 13 7 5 1 47
TMR_00082 0.57 0.45 0.73 43 67837 20 6 10 4 53
TMR_00123 0.68 0.52 0.88 53 66370 12 1 6 5 48
TMR_00137 0.69 0.60 0.79 53 61008 20 7 7 6 36
TMR_00142 0.50 0.40 0.61 41 70809 31 10 16 5 61
TMR_00207 0.60 0.45 0.81 46 72333 18 1 10 7 57
TMR_00257 0.71 0.58 0.88 57 67096 13 3 5 5 41
TMR_00271 0.59 0.48 0.72 44 64200 19 6 11 2 47
TMR_00332 0.70 0.56 0.89 55 67099 12 2 5 5 44
TMR_00366 0.48 0.41 0.57 41 67824 35 9 22 4 59
TMR_00378 0.50 0.41 0.62 40 67831 34 8 17 9 57
TMR_00399 0.70 0.61 0.81 57 64910 21 6 7 8 37
TMR_00404 0.54 0.45 0.66 41 67466 22 8 13 1 51
TMR_00427 0.56 0.43 0.74 42 67471 15 9 6 0 55
TMR_00443 0.76 0.63 0.93 65 67091 11 2 3 6 39
TMR_00451 0.57 0.51 0.65 45 63477 32 11 13 8 44
TMR_00458 0.67 0.57 0.78 53 63478 19 7 8 4 40
TMR_00469 0.73 0.61 0.88 61 64551 11 4 4 3 39
TMR_00472 0.67 0.58 0.79 56 64549 19 9 6 4 41
TMR_00519 0.63 0.54 0.74 51 63121 25 7 11 7 44
TMR_00520 0.65 0.55 0.78 54 63121 18 1 14 3 45
TMR_00522 0.62 0.51 0.77 49 63126 19 6 9 4 48
TMR_00528 0.62 0.51 0.75 49 63125 20 5 11 4 48
TMR_00540 0.69 0.58 0.83 60 73464 14 7 5 2 44
TMR_00568 0.75 0.66 0.87 65 60651 16 2 8 6 34
TMR_00571 0.77 0.68 0.88 67 60650 15 2 7 6 32
TMR_00580 0.76 0.65 0.88 65 60652 15 2 7 6 35
TMR_00584 0.78 0.66 0.93 64 61006 13 2 3 8 33
TMR_00586 0.72 0.63 0.82 61 61001 19 5 8 6 36
TMR_00616 0.68 0.57 0.81 56 67092 17 7 6 4 43
TMR_00699 0.69 0.54 0.87 55 67098 9 1 7 1 47
TMR_00702 0.60 0.45 0.79 45 67104 17 3 9 5 55
TMR_00703 0.71 0.59 0.87 58 67461 14 3 6 5 41

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Performance of CentroidHomfold‑LAST - scored lower in this pairwise comparison

1. Total counts & total scores for CentroidHomfold‑LAST

Total Base Pair Counts
Total TP 11475
Total TN 12001330
Total FP 1780
Total FP CONTRA 225
Total FP INCONS 1084
Total FP COMP 471
Total FN 9345
Total Scores
MCC 0.703
Average MCC ± 95% Confidence Intervals 0.704 ± 0.013
Sensitivity 0.551
Positive Predictive Value 0.898
Nr of predictions 202

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2. Individual counts for CentroidHomfold‑LAST [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.66 0.46 0.94 45 47847 3 1 2 0 52
ASE_00005 0.81 0.67 0.98 78 57890 3 0 2 1 39
ASE_00006 0.67 0.52 0.87 48 47531 7 1 6 0 45
ASE_00007 0.79 0.65 0.95 72 59609 9 0 4 5 38
ASE_00012 0.76 0.62 0.94 76 73839 7 2 3 2 47
ASE_00018 0.82 0.70 0.95 94 80502 7 0 5 2 40
ASE_00020 0.66 0.48 0.91 60 73854 7 1 5 1 66
ASE_00021 0.67 0.47 0.96 75 104118 5 0 3 2 85
ASE_00022 0.67 0.52 0.87 65 82953 13 0 10 3 59
ASE_00028 0.70 0.53 0.92 67 84593 8 0 6 2 59
ASE_00035 0.65 0.44 0.95 52 70445 8 1 2 5 66
ASE_00037 0.78 0.65 0.94 72 59263 8 0 5 3 38
ASE_00040 0.64 0.44 0.94 59 78940 5 2 2 1 74
ASE_00041 0.73 0.56 0.95 61 57566 7 0 3 4 47
ASE_00042 0.74 0.58 0.93 84 90010 6 1 5 0 61
ASE_00044 0.82 0.70 0.97 73 54540 3 0 2 1 32
ASE_00064 0.75 0.61 0.93 54 45393 8 0 4 4 35
ASE_00068 0.70 0.49 1.00 42 37633 0 0 0 0 43
ASE_00074 0.76 0.62 0.94 74 67817 7 1 4 2 45
ASE_00075 0.62 0.42 0.93 68 108738 7 1 4 2 94
ASE_00077 0.77 0.65 0.90 56 45088 7 2 4 1 30
ASE_00078 0.82 0.72 0.94 60 43007 5 1 3 1 23
ASE_00080 0.48 0.30 0.77 37 71583 11 0 11 0 86
ASE_00081 0.71 0.55 0.93 53 49713 5 1 3 1 44
ASE_00082 0.44 0.22 0.89 25 70472 3 0 3 0 91
ASE_00083 0.72 0.56 0.93 62 62414 6 1 4 1 48
ASE_00084 0.73 0.62 0.87 61 53558 11 2 7 2 38
ASE_00090 0.69 0.60 0.78 61 55533 17 1 16 0 40
ASE_00092 0.68 0.49 0.96 55 63489 4 0 2 2 58
ASE_00099 0.82 0.68 0.98 82 64536 3 1 1 1 38
ASE_00104 0.80 0.69 0.93 82 64173 7 1 5 1 37
ASE_00105 0.61 0.43 0.87 48 64206 9 0 7 2 63
ASE_00107 0.78 0.72 0.84 91 73045 19 1 16 2 36
ASE_00115 0.68 0.50 0.93 51 54560 7 0 4 3 50
ASE_00118 0.52 0.27 1.00 28 60698 2 0 0 2 74
ASE_00119 0.34 0.13 0.88 14 62819 2 0 2 0 94
ASE_00123 0.64 0.46 0.89 39 38459 6 1 4 1 46
ASE_00125 0.68 0.50 0.92 44 39292 5 1 3 1 44
ASE_00126 0.75 0.68 0.82 56 40402 13 1 11 1 26
ASE_00128 0.72 0.56 0.93 56 53241 4 1 3 0 44
ASE_00129 0.74 0.64 0.87 71 62753 13 1 10 2 40
ASE_00131 0.63 0.45 0.88 38 39297 9 1 4 4 47
ASE_00134 0.74 0.61 0.91 58 50339 7 1 5 1 37
ASE_00135 0.64 0.46 0.89 50 63134 7 1 5 1 59
ASE_00136 0.75 0.61 0.92 56 48144 8 1 4 3 36
ASE_00137 0.80 0.68 0.93 67 48444 5 1 4 0 31
ASE_00138 0.80 0.65 0.98 53 40416 2 0 1 1 28
ASE_00140 0.66 0.47 0.92 59 70812 7 1 4 2 66
ASE_00142 0.80 0.70 0.92 85 67069 8 3 4 1 37
ASE_00146 0.68 0.54 0.86 67 70798 12 1 10 1 57
ASE_00153 0.54 0.48 0.60 35 57572 43 2 21 20 38
ASE_00163 0.72 0.54 0.96 50 53249 2 0 2 0 43
ASE_00165 0.67 0.50 0.89 51 52918 6 1 5 0 50
ASE_00170 0.70 0.55 0.89 51 48771 6 0 6 0 42
ASE_00171 0.72 0.57 0.92 54 48457 7 1 4 2 40
ASE_00172 0.69 0.49 0.98 52 58943 2 0 1 1 54
ASE_00174 0.66 0.47 0.94 51 61021 3 1 2 0 58
ASE_00175 0.53 0.42 0.66 45 59963 24 3 20 1 62
ASE_00179 0.71 0.52 0.96 44 44207 2 1 1 0 40
ASE_00180 0.70 0.53 0.91 53 51302 6 0 5 1 47
ASE_00181 0.71 0.54 0.95 57 57570 5 0 3 2 49
ASE_00182 0.55 0.35 0.86 48 84199 8 1 7 0 88
ASE_00183 0.67 0.47 0.96 53 61370 3 0 2 1 60
ASE_00184 0.69 0.58 0.83 59 54544 13 2 10 1 43
ASE_00185 0.62 0.41 0.95 52 73481 4 1 2 1 76
ASE_00186 0.79 0.73 0.86 96 78892 16 1 14 1 36
ASE_00190 0.46 0.23 0.91 21 45428 3 0 2 1 69
ASE_00197 0.74 0.64 0.86 93 89145 15 1 14 0 52
ASE_00198 0.80 0.68 0.96 69 52578 3 1 2 0 33
ASE_00203 0.82 0.70 0.96 67 46595 4 1 2 1 29
ASE_00212 0.75 0.65 0.86 96 93849 16 1 15 0 52
ASE_00214 0.69 0.59 0.80 61 56204 17 2 13 2 42
ASE_00215 0.62 0.40 0.95 40 48474 3 1 1 1 59
ASE_00216 0.82 0.71 0.95 58 39279 3 0 3 0 24
ASE_00217 0.67 0.56 0.82 50 40409 14 1 10 3 40
ASE_00221 0.75 0.61 0.93 71 64544 6 1 4 1 46
ASE_00228 0.79 0.69 0.92 59 46907 6 2 3 1 27
ASE_00229 0.79 0.69 0.90 60 42419 7 1 6 0 27
ASE_00231 0.76 0.63 0.92 60 47830 5 1 4 0 36
ASE_00232 0.85 0.75 0.95 63 38437 3 2 1 0 21
ASE_00234 0.61 0.42 0.90 54 75406 8 1 5 2 75
ASE_00238 0.57 0.37 0.89 42 64214 5 0 5 0 72
ASE_00241 0.73 0.64 0.84 56 43889 12 2 9 1 31
ASE_00242 0.81 0.71 0.93 79 60990 7 0 6 1 33
ASE_00248 0.82 0.71 0.94 81 62395 6 0 5 1 33
ASE_00254 0.84 0.74 0.95 61 36792 4 2 1 1 21
ASE_00255 0.73 0.57 0.94 74 74612 5 0 5 0 56
ASE_00257 0.82 0.68 0.99 66 50973 2 0 1 1 31
ASE_00263 0.69 0.48 0.98 58 70441 2 0 1 1 62
ASE_00267 0.72 0.66 0.79 58 45077 17 2 13 2 30
ASE_00270 0.52 0.27 1.00 35 72355 0 0 0 0 93
ASE_00274 0.66 0.47 0.92 48 55559 5 0 4 1 55
ASE_00279 0.72 0.58 0.89 59 53235 8 3 4 1 42
ASE_00280 0.75 0.58 0.97 57 51944 3 0 2 1 41
ASE_00281 0.81 0.68 0.97 60 44489 2 1 1 0 28
ASE_00282 0.60 0.40 0.89 51 77758 7 3 3 1 76
ASE_00283 0.71 0.56 0.91 60 61710 7 2 4 1 47
ASE_00284 0.68 0.51 0.90 55 58250 7 2 4 1 53
ASE_00285 0.63 0.44 0.89 54 68945 8 3 4 1 68
ASE_00286 0.75 0.59 0.95 54 46608 3 1 2 0 38
ASE_00287 0.66 0.49 0.91 50 54891 6 0 5 1 53
ASE_00292 0.55 0.43 0.71 59 81727 25 3 21 1 79
ASE_00294 0.75 0.60 0.94 103 114372 8 1 5 2 68
ASE_00296 0.71 0.53 0.96 77 91726 4 0 3 1 68
ASE_00297 0.68 0.47 0.98 46 52928 1 0 1 0 52
ASE_00298 0.62 0.39 1.00 44 67484 1 0 0 1 69
ASE_00318 0.55 0.35 0.87 41 80153 12 0 6 6 77
ASE_00328 0.80 0.66 0.97 74 72695 9 0 2 7 38
ASE_00332 0.80 0.71 0.89 98 81700 14 1 11 2 40
ASE_00335 0.80 0.66 0.97 76 75388 8 0 2 6 40
ASE_00340 0.63 0.48 0.84 41 46007 11 6 2 3 44
ASE_00342 0.82 0.75 0.90 86 62385 12 1 9 2 29
ASE_00353 0.79 0.69 0.91 74 57889 7 1 6 0 33
ASE_00361 0.65 0.43 0.96 55 75409 4 0 2 2 72
ASE_00362 0.80 0.69 0.93 63 48137 7 1 4 2 28
ASE_00363 0.75 0.64 0.88 60 51292 9 1 7 1 34
ASE_00364 0.79 0.67 0.93 70 54210 6 1 4 1 35
ASE_00366 0.68 0.49 0.94 48 58602 4 0 3 1 50
ASE_00367 0.78 0.70 0.87 60 43002 11 1 8 2 26
ASE_00369 0.79 0.64 0.97 68 55875 2 0 2 0 39
ASE_00372 0.70 0.54 0.90 54 51943 6 3 3 0 46
ASE_00374 0.77 0.64 0.93 56 44790 4 2 2 0 32
ASE_00376 0.65 0.51 0.83 54 56888 15 0 11 4 51
ASE_00377 0.75 0.62 0.92 66 57558 7 0 6 1 41
ASE_00382 0.78 0.69 0.89 58 41840 8 1 6 1 26
ASE_00383 0.79 0.66 0.95 69 54542 5 1 3 1 36
ASE_00384 0.78 0.68 0.90 63 48446 8 1 6 1 29
ASE_00386 0.70 0.56 0.87 54 50341 9 1 7 1 42
ASE_00387 0.63 0.45 0.87 47 55891 8 1 6 1 57
ASE_00388 0.78 0.69 0.90 61 45685 9 1 6 2 28
ASE_00390 0.81 0.72 0.91 61 42128 8 1 5 2 24
ASE_00393 0.70 0.57 0.87 53 47834 9 1 7 1 40
ASE_00394 0.72 0.62 0.83 58 46901 14 1 11 2 35
ASE_00395 0.78 0.71 0.86 60 41546 12 1 9 2 24
ASE_00396 0.78 0.71 0.86 59 41547 12 2 8 2 24
ASE_00397 0.80 0.69 0.92 72 54537 7 1 5 1 33
ASE_00398 0.68 0.53 0.87 55 55882 11 1 7 3 49
ASE_00400 0.67 0.45 0.98 48 57921 1 0 1 0 58
ASE_00401 0.60 0.37 0.98 47 76980 2 0 1 1 79
ASE_00402 0.79 0.68 0.91 58 42422 8 1 5 2 27
ASE_00403 0.75 0.63 0.91 67 55871 7 1 6 0 40
ASE_00404 0.81 0.69 0.94 59 43008 5 0 4 1 26
ASE_00406 0.73 0.62 0.85 58 48760 12 1 9 2 36
ASE_00411 0.64 0.44 0.93 39 49413 3 0 3 0 50
ASE_00412 0.62 0.40 0.98 42 58268 3 0 1 2 63
ASE_00413 0.72 0.54 0.96 44 44505 2 0 2 0 37
ASE_00416 0.58 0.36 0.92 46 77371 5 1 3 1 81
ASE_00419 0.67 0.48 0.94 49 54894 3 1 2 0 54
ASE_00422 0.72 0.55 0.95 52 46916 4 0 3 1 42
ASE_00423 0.76 0.59 0.98 64 56888 2 1 0 1 45
ASE_00428 0.60 0.39 0.91 49 76582 6 1 4 1 76
ASE_00430 0.77 0.61 0.98 59 46911 3 0 1 2 38
ASE_00437 0.55 0.47 0.66 63 79305 35 1 32 2 72
ASE_00441 0.63 0.44 0.91 49 64207 9 0 5 4 63
ASE_00448 0.75 0.63 0.88 71 64180 11 1 9 1 41
ASE_00451 0.77 0.72 0.83 90 70768 20 1 17 2 35
PDB_00571 0.87 0.80 0.95 20 3300 1 1 0 0 5
PDB_00828 0.84 0.70 1.00 19 2466 0 0 0 0 8
PDB_00829 0.84 0.71 1.00 17 2261 0 0 0 0 7
PDB_01020 0.86 0.74 1.00 17 2261 0 0 0 0 6
PDB_01073 0.84 0.71 1.00 24 4347 1 0 0 1 10
RFA_00599 0.65 0.46 0.91 51 101419 10 3 2 5 60
RFA_00601 0.86 0.82 0.91 93 99133 20 3 6 11 21
TMR_00017 0.72 0.55 0.93 56 67101 8 0 4 4 46
TMR_00018 0.71 0.60 0.85 55 64555 14 2 8 4 37
TMR_00038 0.67 0.49 0.92 54 71194 7 3 2 2 56
TMR_00042 0.74 0.64 0.85 63 62761 15 1 10 4 35
TMR_00046 0.64 0.53 0.77 51 62769 20 3 12 5 45
TMR_00048 0.73 0.63 0.85 60 64909 18 2 9 7 35
TMR_00080 0.60 0.36 0.97 35 70464 1 0 1 0 61
TMR_00082 0.65 0.44 0.95 42 67852 3 0 2 1 54
TMR_00123 0.69 0.55 0.86 56 66365 14 0 9 5 45
TMR_00137 0.47 0.28 0.78 25 61043 12 1 6 5 64
TMR_00142 0.61 0.55 0.68 56 70794 33 7 19 7 46
TMR_00207 0.76 0.60 0.95 62 72325 7 0 3 4 41
TMR_00257 0.71 0.54 0.93 53 67104 10 0 4 6 45
TMR_00271 0.54 0.35 0.82 32 64222 15 3 4 8 59
TMR_00332 0.75 0.62 0.92 61 67095 10 0 5 5 38
TMR_00366 0.65 0.57 0.74 57 67819 31 5 15 11 43
TMR_00378 0.63 0.53 0.76 51 67829 26 6 10 10 46
TMR_00399 0.45 0.31 0.66 29 64936 25 7 8 10 65
TMR_00404 0.66 0.57 0.76 52 67460 27 3 13 11 40
TMR_00427 0.73 0.59 0.90 57 67465 11 5 1 5 40
TMR_00443 0.69 0.55 0.86 57 67095 13 1 8 4 47
TMR_00451 0.54 0.36 0.80 32 63506 12 3 5 4 57
TMR_00458 0.61 0.41 0.90 38 63504 7 3 1 3 55
TMR_00469 0.79 0.70 0.90 70 64542 11 4 4 3 30
TMR_00472 0.77 0.66 0.89 64 64548 13 5 3 5 33
TMR_00519 0.61 0.46 0.80 44 63135 20 2 9 9 51
TMR_00520 0.60 0.47 0.76 47 63128 24 3 12 9 52
TMR_00522 0.65 0.47 0.88 46 63138 14 2 4 8 51
TMR_00528 0.60 0.46 0.78 45 63132 22 4 9 9 52
TMR_00540 0.69 0.54 0.88 56 73472 11 2 6 3 48
TMR_00568 0.69 0.54 0.88 53 60666 15 0 7 8 46
TMR_00571 0.66 0.49 0.89 49 60671 14 1 5 8 50
TMR_00580 0.65 0.49 0.88 49 60670 14 1 6 7 51
TMR_00584 0.72 0.57 0.92 55 61015 13 1 4 8 42
TMR_00586 0.70 0.56 0.89 54 61014 14 1 6 7 43
TMR_00616 0.76 0.63 0.91 62 67093 11 0 6 5 37
TMR_00699 0.76 0.63 0.91 64 67091 11 1 5 5 38
TMR_00702 0.77 0.65 0.90 65 67089 12 1 6 5 35
TMR_00703 0.78 0.66 0.92 65 67457 11 1 5 5 34

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.