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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of Multilign(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & Multilign(20) [.zip] - may take several seconds...


Overview

Metric PPfold(20) Multilign(20)
MCC 0.735 > 0.652
Average MCC ± 95% Confidence Intervals 0.738 ± 0.014 > 0.657 ± 0.017
Sensitivity 0.635 > 0.591
Positive Predictive Value 0.852 > 0.719
Total TP 12375 > 11513
Total TN 11164588 > 11163115
Total FP 2965 < 5276
Total FP CONTRA 551 < 608
Total FP INCONS 1605 < 3883
Total FP COMP 809 > 785
Total FN 7098 < 7960
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of PPfold(20) and Multilign(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and Multilign(20)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for PPfold(20) and Multilign(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and Multilign(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and Multilign(20)).

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Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 12375
Total TN 11164588
Total FP 2965
Total FP CONTRA 551
Total FP INCONS 1605
Total FP COMP 809
Total FN 7098
Total Scores
MCC 0.735
Average MCC ± 95% Confidence Intervals 0.738 ± 0.014
Sensitivity 0.635
Positive Predictive Value 0.852
Nr of predictions 190

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00005 0.75 0.64 0.88 75 57885 13 3 7 3 42
ASE_00006 0.69 0.60 0.80 56 47516 16 1 13 2 37
ASE_00007 0.85 0.81 0.89 89 59585 15 2 9 4 21
ASE_00012 0.74 0.67 0.82 83 73819 24 4 14 6 40
ASE_00018 0.77 0.66 0.90 89 80502 14 3 7 4 45
ASE_00020 0.66 0.52 0.84 66 73841 19 6 7 6 60
ASE_00021 0.55 0.44 0.69 70 104095 36 5 26 5 90
ASE_00035 0.80 0.73 0.88 86 70402 19 1 11 7 32
ASE_00037 0.86 0.81 0.92 89 59243 13 1 7 5 21
ASE_00040 0.81 0.71 0.92 95 78900 10 3 5 2 38
ASE_00041 0.83 0.81 0.85 88 57527 18 2 13 3 20
ASE_00042 0.67 0.57 0.80 82 89998 23 2 18 3 63
ASE_00044 0.89 0.86 0.92 90 54517 10 2 6 2 15
ASE_00064 0.80 0.73 0.87 65 45376 15 1 9 5 24
ASE_00068 0.64 0.54 0.75 46 37614 17 5 10 2 39
ASE_00074 0.85 0.78 0.93 93 67796 12 1 6 5 26
ASE_00075 0.57 0.44 0.72 72 108711 35 5 23 7 90
ASE_00077 0.85 0.83 0.88 71 45069 14 5 5 4 15
ASE_00078 0.91 0.87 0.95 72 42995 11 1 3 7 11
ASE_00080 0.44 0.35 0.57 43 71555 36 2 31 3 80
ASE_00081 0.82 0.73 0.92 71 49693 9 2 4 3 26
ASE_00082 0.65 0.52 0.81 60 70426 22 1 13 8 56
ASE_00083 0.74 0.62 0.89 68 62405 13 3 5 5 42
ASE_00084 0.74 0.65 0.84 64 53552 16 2 10 4 35
ASE_00090 0.78 0.67 0.91 68 55536 11 2 5 4 33
ASE_00092 0.65 0.53 0.79 60 63470 21 3 13 5 53
ASE_00099 0.85 0.78 0.93 93 64520 11 2 5 4 27
ASE_00104 0.83 0.76 0.91 91 64161 15 1 8 6 28
ASE_00105 0.59 0.50 0.70 56 64181 29 6 18 5 55
ASE_00107 0.83 0.75 0.92 95 73050 11 2 6 3 32
ASE_00115 0.78 0.68 0.88 69 54537 12 2 7 3 32
ASE_00118 0.70 0.60 0.82 61 60652 17 2 11 4 41
ASE_00119 0.70 0.54 0.92 58 62772 8 2 3 3 50
ASE_00123 0.69 0.59 0.82 50 38442 14 3 8 3 35
ASE_00126 0.85 0.79 0.90 65 40398 13 2 5 6 17
ASE_00128 0.80 0.70 0.92 70 53225 10 2 4 4 30
ASE_00129 0.77 0.65 0.92 72 62757 9 3 3 3 39
ASE_00131 0.75 0.62 0.90 53 39281 12 2 4 6 32
ASE_00134 0.75 0.68 0.83 65 50325 16 1 12 3 30
ASE_00135 0.63 0.54 0.74 59 63110 24 3 18 3 50
ASE_00136 0.79 0.72 0.88 66 48130 12 2 7 3 26
ASE_00137 0.80 0.66 0.97 65 48449 7 1 1 5 33
ASE_00138 0.84 0.78 0.91 63 40401 10 2 4 4 18
ASE_00140 0.69 0.55 0.86 69 70796 17 7 4 6 56
ASE_00142 0.83 0.74 0.93 90 67064 13 2 5 6 32
ASE_00146 0.81 0.71 0.92 88 70780 13 1 7 5 36
ASE_00153 0.43 0.37 0.50 27 57576 32 4 23 5 46
ASE_00163 0.83 0.76 0.90 71 53222 12 1 7 4 22
ASE_00165 0.79 0.66 0.94 67 52904 10 2 2 6 34
ASE_00170 0.73 0.66 0.80 61 48752 20 2 13 5 32
ASE_00171 0.82 0.74 0.91 70 48439 11 3 4 4 24
ASE_00172 0.77 0.65 0.91 69 58920 10 3 4 3 37
ASE_00174 0.66 0.54 0.80 59 61001 18 3 12 3 50
ASE_00175 0.73 0.64 0.85 68 59951 17 3 9 5 39
ASE_00179 0.83 0.80 0.87 67 44176 15 5 5 5 17
ASE_00180 0.78 0.69 0.88 69 51282 12 3 6 3 31
ASE_00181 0.70 0.59 0.83 63 57554 18 4 9 5 43
ASE_00182 0.69 0.53 0.90 72 84175 11 3 5 3 64
ASE_00183 0.76 0.65 0.90 73 61344 12 2 6 4 40
ASE_00184 0.77 0.68 0.87 69 54536 13 2 8 3 33
ASE_00185 0.68 0.52 0.90 66 73463 12 3 4 5 62
ASE_00190 0.75 0.64 0.87 58 45384 12 1 8 3 32
ASE_00197 0.67 0.55 0.81 80 89154 24 2 17 5 65
ASE_00198 0.80 0.70 0.92 71 52573 9 1 5 3 31
ASE_00203 0.80 0.72 0.90 69 46588 13 3 5 5 27
ASE_00212 0.66 0.53 0.83 78 93867 20 2 14 4 70
ASE_00214 0.77 0.66 0.91 68 56205 11 3 4 4 35
ASE_00215 0.62 0.46 0.82 46 48460 13 2 8 3 53
ASE_00216 0.91 0.84 0.99 69 39270 5 1 0 4 13
ASE_00217 0.83 0.77 0.91 69 40394 11 2 5 4 21
ASE_00221 0.85 0.78 0.93 91 64522 10 1 6 3 26
ASE_00228 0.75 0.69 0.83 59 46900 16 2 10 4 27
ASE_00229 0.88 0.79 0.97 69 42415 5 2 0 3 18
ASE_00231 0.67 0.57 0.77 55 47824 22 1 15 6 41
ASE_00232 0.89 0.82 0.97 69 38432 6 1 1 4 15
ASE_00234 0.66 0.53 0.83 68 75384 20 6 8 6 61
ASE_00238 0.67 0.56 0.80 64 64181 22 5 11 6 50
ASE_00241 0.83 0.78 0.87 68 43878 14 1 9 4 19
ASE_00242 0.86 0.82 0.90 92 60973 15 1 9 5 20
ASE_00254 0.85 0.77 0.94 63 36789 8 2 2 4 19
ASE_00257 0.73 0.65 0.82 63 50963 17 4 10 3 34
ASE_00263 0.70 0.57 0.87 68 70422 14 3 7 4 52
ASE_00267 0.84 0.77 0.91 68 45075 13 2 5 6 20
ASE_00270 0.58 0.43 0.79 55 72320 19 2 13 4 73
ASE_00274 0.68 0.60 0.78 62 55531 21 5 13 3 41
ASE_00279 0.79 0.69 0.90 70 53223 11 3 5 3 31
ASE_00280 0.74 0.66 0.82 65 51924 17 3 11 3 33
ASE_00281 0.81 0.75 0.87 66 44475 12 3 7 2 22
ASE_00282 0.70 0.54 0.90 69 77738 12 2 6 4 58
ASE_00283 0.73 0.63 0.86 67 61698 14 2 9 3 40
ASE_00284 0.77 0.66 0.91 71 58233 11 4 3 4 37
ASE_00285 0.70 0.55 0.91 67 68932 11 2 5 4 55
ASE_00286 0.81 0.73 0.89 67 46590 12 2 6 4 25
ASE_00287 0.69 0.60 0.79 62 54868 20 1 15 4 41
ASE_00292 0.72 0.62 0.83 86 81707 20 2 15 3 52
ASE_00294 0.72 0.57 0.92 97 114375 13 2 7 4 74
ASE_00296 0.72 0.61 0.86 88 91704 18 4 10 4 57
ASE_00297 0.68 0.58 0.79 57 52903 19 4 11 4 41
ASE_00298 0.72 0.61 0.85 69 67447 15 3 9 3 44
ASE_00328 0.81 0.75 0.88 84 72675 19 1 11 7 28
ASE_00332 0.78 0.67 0.91 92 81709 12 3 6 3 46
ASE_00340 0.75 0.67 0.85 57 45989 17 1 9 7 28
ASE_00342 0.89 0.83 0.96 95 62382 9 1 3 5 20
ASE_00353 0.75 0.64 0.88 68 57893 14 2 7 5 39
ASE_00361 0.69 0.53 0.89 67 75391 13 3 5 5 60
ASE_00362 0.80 0.71 0.89 65 48132 14 2 6 6 26
ASE_00363 0.76 0.68 0.84 64 51284 17 2 10 5 30
ASE_00364 0.76 0.66 0.87 69 54206 15 3 7 5 36
ASE_00366 0.76 0.67 0.87 66 58577 13 3 7 3 32
ASE_00367 0.85 0.79 0.91 68 42996 11 2 5 4 18
ASE_00369 0.79 0.69 0.90 74 55863 13 1 7 5 33
ASE_00372 0.76 0.65 0.88 65 51929 15 1 8 6 35
ASE_00374 0.86 0.80 0.93 70 44775 8 2 3 3 18
ASE_00376 0.73 0.63 0.85 66 56875 15 1 11 3 39
ASE_00377 0.76 0.65 0.88 70 57550 13 3 7 3 37
ASE_00382 0.83 0.80 0.87 67 41828 16 2 8 6 17
ASE_00383 0.77 0.66 0.90 69 54538 13 1 7 5 36
ASE_00384 0.81 0.74 0.89 68 48440 13 2 6 5 24
ASE_00386 0.79 0.71 0.88 68 50326 12 2 7 3 28
ASE_00387 0.71 0.62 0.83 64 55868 17 2 11 4 40
ASE_00388 0.80 0.73 0.87 65 45678 16 1 9 6 24
ASE_00390 0.85 0.80 0.89 68 42119 11 2 6 3 17
ASE_00393 0.74 0.68 0.82 63 47818 19 1 13 5 30
ASE_00394 0.83 0.74 0.92 69 46896 10 2 4 4 24
ASE_00395 0.83 0.79 0.87 66 41540 13 2 8 3 18
ASE_00396 0.86 0.83 0.90 69 41539 12 3 5 4 14
ASE_00397 0.75 0.64 0.88 67 54539 15 3 6 6 38
ASE_00398 0.74 0.63 0.87 65 55870 13 1 9 3 39
ASE_00400 0.79 0.67 0.92 71 57893 12 1 5 6 35
ASE_00401 0.67 0.51 0.88 64 76955 13 2 7 4 62
ASE_00402 0.85 0.80 0.89 68 42410 12 2 6 4 17
ASE_00403 0.79 0.67 0.92 72 55867 12 1 5 6 35
ASE_00404 0.85 0.80 0.89 68 42995 14 4 4 6 17
ASE_00406 0.79 0.72 0.86 68 48749 14 2 9 3 26
ASE_00411 0.70 0.67 0.72 60 49372 27 7 16 4 29
ASE_00412 0.62 0.54 0.71 57 58231 28 5 18 5 48
ASE_00413 0.76 0.73 0.79 59 44476 23 4 12 7 22
ASE_00416 0.74 0.66 0.82 84 77319 23 4 14 5 43
ASE_00419 0.72 0.61 0.84 63 54871 16 5 7 4 40
ASE_00422 0.82 0.73 0.91 69 46895 13 1 6 6 25
ASE_00423 0.75 0.71 0.80 77 56857 23 3 16 4 32
ASE_00428 0.75 0.68 0.83 85 76533 21 4 14 3 40
ASE_00430 0.75 0.66 0.85 64 46896 14 1 10 3 33
ASE_00437 0.58 0.50 0.69 67 79304 33 1 29 3 68
ASE_00441 0.70 0.57 0.86 64 64187 13 3 7 3 48
ASE_00448 0.83 0.79 0.87 88 64160 15 3 10 2 24
ASE_00451 0.81 0.73 0.91 91 70776 12 1 8 3 34
PDB_00571 0.87 0.80 0.95 20 3300 1 1 0 0 5
PDB_00828 0.84 0.70 1.00 19 2466 2 0 0 2 8
PDB_00829 0.86 0.75 1.00 18 2260 2 0 0 2 6
PDB_01020 0.86 0.74 1.00 17 2261 3 0 0 3 6
PDB_01073 0.79 0.71 0.89 24 4344 4 2 1 1 10
RFA_00599 0.86 0.80 0.93 89 101379 16 3 4 9 22
RFA_00601 0.77 0.68 0.89 77 99148 20 1 9 10 37
TMR_00017 0.71 0.55 0.92 56 67100 8 1 4 3 46
TMR_00018 0.63 0.52 0.76 48 64557 21 6 9 6 44
TMR_00038 0.61 0.52 0.73 57 71175 26 5 16 5 53
TMR_00042 0.62 0.49 0.79 48 62774 13 4 9 0 50
TMR_00046 0.46 0.36 0.58 35 62775 26 4 21 1 61
TMR_00048 0.63 0.52 0.77 49 64916 16 7 8 1 46
TMR_00080 0.64 0.51 0.80 49 70439 13 7 5 1 47
TMR_00082 0.57 0.45 0.73 43 67837 20 6 10 4 53
TMR_00123 0.68 0.52 0.88 53 66370 12 1 6 5 48
TMR_00137 0.69 0.60 0.79 53 61008 20 7 7 6 36
TMR_00142 0.50 0.40 0.61 41 70809 31 10 16 5 61
TMR_00207 0.60 0.45 0.81 46 72333 18 1 10 7 57
TMR_00257 0.71 0.58 0.88 57 67096 13 3 5 5 41
TMR_00271 0.59 0.48 0.72 44 64200 19 6 11 2 47
TMR_00366 0.48 0.41 0.57 41 67824 35 9 22 4 59
TMR_00378 0.50 0.41 0.62 40 67831 34 8 17 9 57
TMR_00399 0.70 0.61 0.81 57 64910 21 6 7 8 37
TMR_00404 0.54 0.45 0.66 41 67466 22 8 13 1 51
TMR_00427 0.56 0.43 0.74 42 67471 15 9 6 0 55
TMR_00443 0.76 0.63 0.93 65 67091 11 2 3 6 39
TMR_00451 0.57 0.51 0.65 45 63477 32 11 13 8 44
TMR_00458 0.67 0.57 0.78 53 63478 19 7 8 4 40
TMR_00469 0.73 0.61 0.88 61 64551 11 4 4 3 39
TMR_00472 0.67 0.58 0.79 56 64549 19 9 6 4 41
TMR_00519 0.63 0.54 0.74 51 63121 25 7 11 7 44
TMR_00520 0.65 0.55 0.78 54 63121 18 1 14 3 45
TMR_00522 0.62 0.51 0.77 49 63126 19 6 9 4 48
TMR_00528 0.62 0.51 0.75 49 63125 20 5 11 4 48
TMR_00568 0.75 0.66 0.87 65 60651 16 2 8 6 34
TMR_00571 0.77 0.68 0.88 67 60650 15 2 7 6 32
TMR_00580 0.76 0.65 0.88 65 60652 15 2 7 6 35
TMR_00584 0.78 0.66 0.93 64 61006 13 2 3 8 33
TMR_00586 0.72 0.63 0.82 61 61001 19 5 8 6 36
TMR_00616 0.68 0.57 0.81 56 67092 17 7 6 4 43
TMR_00699 0.69 0.54 0.87 55 67098 9 1 7 1 47
TMR_00702 0.60 0.45 0.79 45 67104 17 3 9 5 55

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Performance of Multilign(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 11513
Total TN 11163115
Total FP 5276
Total FP CONTRA 608
Total FP INCONS 3883
Total FP COMP 785
Total FN 7960
Total Scores
MCC 0.652
Average MCC ± 95% Confidence Intervals 0.657 ± 0.017
Sensitivity 0.591
Positive Predictive Value 0.719
Nr of predictions 190

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2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00005 0.73 0.66 0.82 77 57876 23 0 17 6 40
ASE_00006 0.78 0.76 0.81 71 47498 22 1 16 5 22
ASE_00007 0.70 0.63 0.78 69 59596 25 0 20 5 41
ASE_00012 0.62 0.56 0.69 69 73820 36 3 28 5 54
ASE_00018 0.75 0.67 0.84 90 80494 19 1 16 2 44
ASE_00020 0.49 0.43 0.56 54 73823 43 4 39 0 72
ASE_00021 0.62 0.51 0.75 82 104086 30 5 23 2 78
ASE_00035 0.62 0.57 0.68 67 70402 35 3 28 4 51
ASE_00037 0.56 0.49 0.64 54 59255 31 4 27 0 56
ASE_00040 0.69 0.62 0.75 83 78893 28 0 27 1 50
ASE_00041 0.72 0.67 0.78 72 57538 21 1 19 1 36
ASE_00042 0.50 0.41 0.61 60 90002 41 2 36 3 85
ASE_00044 0.83 0.77 0.89 81 54524 12 0 10 2 24
ASE_00064 0.76 0.67 0.86 60 45381 21 0 10 11 29
ASE_00068 0.76 0.71 0.82 60 37602 17 0 13 4 25
ASE_00074 0.82 0.78 0.87 93 67789 14 1 13 0 26
ASE_00075 0.75 0.64 0.87 104 108691 24 3 13 8 58
ASE_00077 0.61 0.55 0.67 47 45080 33 5 18 10 39
ASE_00078 0.81 0.77 0.84 64 42995 18 0 12 6 19
ASE_00080 0.52 0.48 0.57 59 71528 44 5 39 0 64
ASE_00081 0.80 0.75 0.86 73 49685 13 0 12 1 24
ASE_00082 0.58 0.53 0.63 62 70402 47 3 33 11 54
ASE_00083 0.82 0.74 0.91 81 62392 10 0 8 2 29
ASE_00084 0.60 0.55 0.67 54 53547 27 1 26 0 45
ASE_00090 0.52 0.46 0.60 46 55534 36 5 26 5 55
ASE_00092 0.69 0.63 0.76 71 63452 24 0 23 1 42
ASE_00099 0.81 0.76 0.86 91 64514 16 2 13 1 29
ASE_00104 0.82 0.76 0.89 90 64160 16 1 10 5 29
ASE_00105 0.53 0.49 0.58 54 64168 41 6 33 2 57
ASE_00107 0.64 0.57 0.73 72 73055 28 1 25 2 55
ASE_00115 0.72 0.61 0.84 62 54541 12 1 11 0 39
ASE_00118 0.55 0.49 0.62 50 60645 33 1 30 2 52
ASE_00119 0.55 0.50 0.61 54 62747 36 1 33 2 54
ASE_00123 0.55 0.51 0.60 43 38431 33 1 28 4 42
ASE_00126 0.70 0.70 0.71 57 40390 30 3 20 7 25
ASE_00128 0.74 0.62 0.87 62 53230 13 1 8 4 38
ASE_00129 0.69 0.63 0.75 70 62742 23 2 21 0 41
ASE_00131 0.48 0.42 0.54 36 39273 36 2 29 5 49
ASE_00134 0.71 0.67 0.74 64 50317 23 3 19 1 31
ASE_00135 0.54 0.49 0.60 53 63102 40 6 29 5 56
ASE_00136 0.83 0.78 0.89 72 48124 16 0 9 7 20
ASE_00137 0.52 0.48 0.56 47 48432 42 0 37 5 51
ASE_00138 0.79 0.73 0.87 59 40402 12 3 6 3 22
ASE_00140 0.46 0.38 0.55 48 70789 40 3 36 1 77
ASE_00142 0.72 0.67 0.78 82 67056 25 3 20 2 40
ASE_00146 0.64 0.54 0.76 67 70788 22 1 20 1 57
ASE_00153 0.38 0.37 0.39 27 57560 76 9 34 33 46
ASE_00163 0.69 0.67 0.71 62 53214 27 7 18 2 31
ASE_00165 0.54 0.49 0.60 49 52893 35 6 27 2 52
ASE_00170 0.83 0.77 0.90 72 48748 10 2 6 2 21
ASE_00171 0.88 0.80 0.96 75 48438 8 0 3 5 19
ASE_00172 0.66 0.58 0.76 61 58916 25 3 16 6 45
ASE_00174 0.53 0.45 0.63 49 60997 32 1 28 3 60
ASE_00175 0.63 0.55 0.73 59 59950 27 2 20 5 48
ASE_00179 0.76 0.69 0.84 58 44184 15 1 10 4 26
ASE_00180 0.77 0.70 0.85 70 51278 15 3 9 3 30
ASE_00181 0.67 0.63 0.71 67 57536 30 0 27 3 39
ASE_00182 0.48 0.40 0.57 55 84158 42 2 40 0 81
ASE_00183 0.70 0.63 0.77 71 61333 23 0 21 2 42
ASE_00184 0.76 0.68 0.85 69 54534 20 0 12 8 33
ASE_00185 0.42 0.38 0.47 48 73434 58 2 52 4 80
ASE_00190 0.46 0.37 0.57 33 45393 28 4 21 3 57
ASE_00197 0.42 0.36 0.50 52 89150 54 1 50 3 93
ASE_00198 0.63 0.58 0.69 59 52564 30 3 24 3 43
ASE_00203 0.56 0.52 0.61 50 46583 36 0 32 4 46
ASE_00212 0.66 0.59 0.74 88 93842 33 1 30 2 60
ASE_00214 0.83 0.79 0.87 81 56187 17 3 9 5 22
ASE_00215 0.18 0.15 0.23 15 48450 55 4 47 4 84
ASE_00216 0.71 0.67 0.74 55 39266 26 2 17 7 27
ASE_00217 0.50 0.46 0.55 41 40395 39 1 33 5 49
ASE_00221 0.65 0.56 0.74 66 64531 24 0 23 1 51
ASE_00228 0.69 0.67 0.72 58 46890 26 4 19 3 28
ASE_00229 0.60 0.57 0.63 50 42406 32 4 26 2 37
ASE_00231 0.44 0.40 0.50 38 47819 42 3 35 4 58
ASE_00232 0.81 0.81 0.81 68 38419 17 6 10 1 16
ASE_00234 0.68 0.60 0.76 78 75363 27 6 19 2 51
ASE_00238 0.50 0.45 0.55 51 64169 42 6 35 1 63
ASE_00241 0.78 0.71 0.86 62 43884 15 1 9 5 25
ASE_00242 0.72 0.66 0.80 74 60982 24 1 18 5 38
ASE_00254 0.48 0.46 0.50 38 36780 39 5 33 1 44
ASE_00257 0.70 0.64 0.78 62 50960 25 1 17 7 35
ASE_00263 0.46 0.41 0.52 49 70405 47 6 40 1 71
ASE_00267 0.75 0.68 0.82 60 45077 21 1 12 8 28
ASE_00270 0.56 0.49 0.64 63 72292 38 2 33 3 65
ASE_00274 0.59 0.51 0.67 53 55532 28 5 21 2 50
ASE_00279 0.78 0.73 0.82 74 53211 20 2 14 4 27
ASE_00280 0.72 0.66 0.78 65 51920 21 1 17 3 33
ASE_00281 0.80 0.73 0.89 64 44479 15 1 7 7 24
ASE_00282 0.48 0.42 0.56 53 77721 42 3 38 1 74
ASE_00283 0.73 0.67 0.80 72 61686 23 0 18 5 35
ASE_00284 0.65 0.59 0.71 64 58221 29 3 23 3 44
ASE_00285 0.58 0.51 0.67 62 68914 32 3 27 2 60
ASE_00286 0.82 0.74 0.91 68 46590 10 1 6 3 24
ASE_00287 0.62 0.56 0.68 58 54861 28 0 27 1 45
ASE_00292 0.74 0.64 0.84 89 81704 22 2 15 5 49
ASE_00294 0.75 0.63 0.89 108 114359 16 1 13 2 63
ASE_00296 0.64 0.54 0.76 78 91704 26 1 23 2 67
ASE_00297 0.62 0.53 0.72 52 52903 21 1 19 1 46
ASE_00298 0.48 0.43 0.53 49 67435 46 2 42 2 64
ASE_00328 0.76 0.67 0.87 75 72685 23 1 10 12 37
ASE_00332 0.45 0.37 0.55 51 81717 44 3 39 2 87
ASE_00340 0.58 0.54 0.63 46 45983 31 8 19 4 39
ASE_00342 0.82 0.76 0.88 87 62382 12 2 10 0 28
ASE_00353 0.65 0.62 0.69 66 57874 35 2 28 5 41
ASE_00361 0.58 0.49 0.69 62 75376 29 3 25 1 65
ASE_00362 0.74 0.65 0.86 59 48136 10 0 10 0 32
ASE_00363 0.81 0.73 0.90 69 51283 14 1 7 6 25
ASE_00364 0.63 0.56 0.71 59 54202 29 1 23 5 46
ASE_00366 0.62 0.57 0.67 56 58570 31 6 21 4 42
ASE_00367 0.57 0.53 0.61 46 42995 36 1 29 6 40
ASE_00369 0.82 0.74 0.92 79 55859 7 1 6 0 28
ASE_00372 0.67 0.59 0.77 59 51926 19 1 17 1 41
ASE_00374 0.81 0.73 0.90 64 44779 8 1 6 1 24
ASE_00376 0.66 0.61 0.71 64 56863 28 1 25 2 41
ASE_00377 0.61 0.55 0.69 59 57544 29 3 24 2 48
ASE_00382 0.86 0.81 0.92 68 41831 14 0 6 8 16
ASE_00383 0.79 0.72 0.85 76 54526 14 4 9 1 29
ASE_00384 0.70 0.65 0.75 60 48436 26 4 16 6 32
ASE_00386 0.65 0.60 0.70 58 50320 27 5 20 2 38
ASE_00387 0.67 0.63 0.70 66 55851 29 0 28 1 38
ASE_00388 0.51 0.47 0.56 42 45678 40 2 31 7 47
ASE_00390 0.85 0.80 0.89 68 42119 17 0 8 9 17
ASE_00393 0.70 0.63 0.77 59 47818 20 1 17 2 34
ASE_00394 0.80 0.72 0.88 67 46895 13 4 5 4 26
ASE_00395 0.73 0.69 0.77 58 41541 21 0 17 4 26
ASE_00396 0.72 0.66 0.79 55 41546 19 2 13 4 28
ASE_00397 0.74 0.69 0.79 72 54524 23 1 18 4 33
ASE_00398 0.68 0.62 0.76 64 55861 29 1 19 9 40
ASE_00400 0.74 0.69 0.80 73 57879 19 1 17 1 33
ASE_00401 0.52 0.44 0.63 55 76940 40 0 33 7 71
ASE_00402 0.76 0.69 0.84 59 42416 15 1 10 4 26
ASE_00403 0.66 0.58 0.76 62 55863 25 3 17 5 45
ASE_00404 0.78 0.73 0.83 62 42996 17 1 12 4 23
ASE_00406 0.82 0.73 0.91 69 48752 15 0 7 8 25
ASE_00411 0.57 0.53 0.62 47 49379 30 10 19 1 42
ASE_00412 0.56 0.50 0.62 53 58226 34 3 29 2 52
ASE_00413 0.60 0.57 0.64 46 44479 27 2 24 1 35
ASE_00416 0.69 0.59 0.80 75 77327 28 1 18 9 52
ASE_00419 0.75 0.68 0.83 70 54862 16 3 11 2 33
ASE_00422 0.65 0.63 0.67 59 46883 30 4 25 1 35
ASE_00423 0.84 0.77 0.92 84 56862 10 1 6 3 25
ASE_00428 0.57 0.54 0.60 68 76522 47 4 42 1 57
ASE_00430 0.79 0.76 0.82 74 46881 16 2 14 0 23
ASE_00437 0.67 0.60 0.75 81 79293 27 1 26 0 54
ASE_00441 0.66 0.57 0.77 64 64178 19 2 17 0 48
ASE_00448 0.63 0.59 0.67 66 64163 39 2 30 7 46
ASE_00451 0.68 0.60 0.77 75 70779 24 1 21 2 50
PDB_00571 0.85 0.76 0.95 19 3301 1 1 0 0 6
PDB_00828 0.88 0.78 1.00 21 2464 0 0 0 0 6
PDB_00829 0.86 0.75 1.00 18 2260 2 0 0 2 6
PDB_01020 0.86 0.74 1.00 17 2261 3 0 0 3 6
PDB_01073 0.86 0.74 1.00 25 4346 1 0 0 1 9
RFA_00599 0.71 0.71 0.71 79 101363 50 13 20 17 32
RFA_00601 0.58 0.54 0.61 62 99134 50 10 29 11 52
TMR_00017 0.59 0.56 0.62 57 67069 39 8 27 4 45
TMR_00018 0.59 0.54 0.65 50 64543 31 7 20 4 42
TMR_00038 0.73 0.66 0.79 73 71161 24 1 18 5 37
TMR_00042 0.61 0.57 0.65 56 62749 34 7 23 4 42
TMR_00046 0.65 0.63 0.67 60 62746 35 9 20 6 36
TMR_00048 0.59 0.55 0.63 52 64898 38 6 24 8 43
TMR_00080 0.51 0.46 0.56 44 70422 34 10 24 0 52
TMR_00082 0.65 0.59 0.71 57 67816 30 7 16 7 39
TMR_00123 0.64 0.59 0.68 60 66342 34 4 24 6 41
TMR_00137 0.33 0.28 0.38 25 61009 44 9 32 3 64
TMR_00142 0.62 0.64 0.61 65 70769 49 12 30 7 37
TMR_00207 0.40 0.35 0.45 36 72310 49 6 38 5 67
TMR_00257 0.68 0.61 0.76 60 67082 27 4 15 8 38
TMR_00271 0.64 0.56 0.74 51 64192 20 6 12 2 40
TMR_00366 0.64 0.60 0.67 60 67807 40 12 17 11 40
TMR_00378 0.67 0.63 0.71 61 67810 38 5 20 13 36
TMR_00399 0.48 0.45 0.52 42 64899 46 9 30 7 52
TMR_00404 0.59 0.59 0.60 54 67438 49 12 24 13 38
TMR_00427 0.53 0.41 0.69 40 67470 22 7 11 4 57
TMR_00443 0.67 0.59 0.77 61 67082 22 4 14 4 43
TMR_00451 0.52 0.45 0.60 40 63479 31 7 20 4 49
TMR_00458 0.70 0.63 0.77 59 63469 21 4 14 3 34
TMR_00469 0.75 0.73 0.78 73 64526 30 7 14 9 27
TMR_00472 0.76 0.73 0.80 71 64531 23 7 11 5 26
TMR_00519 0.60 0.57 0.64 54 63106 34 12 18 4 41
TMR_00520 0.67 0.62 0.73 61 63106 31 4 19 8 38
TMR_00522 0.53 0.47 0.60 46 63113 36 9 22 5 51
TMR_00528 0.51 0.45 0.58 44 63114 37 10 22 5 53
TMR_00568 0.62 0.59 0.65 58 60637 40 8 23 9 41
TMR_00571 0.69 0.65 0.73 64 60638 34 10 14 10 35
TMR_00580 0.62 0.61 0.63 61 60629 46 10 26 10 39
TMR_00584 0.65 0.61 0.69 59 60989 36 6 21 9 38
TMR_00586 0.60 0.59 0.61 57 60982 43 11 25 7 40
TMR_00616 0.65 0.63 0.68 62 67070 35 7 22 6 37
TMR_00699 0.69 0.60 0.80 61 67085 16 2 13 1 41
TMR_00702 0.63 0.54 0.73 54 67087 26 7 13 6 46

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.