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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(20) - scored higher in this pairwise comparison

  4. Performance of Afold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(20) & Afold [.zip] - may take several seconds...


Overview

Metric RNAalifold(20) Afold
MCC 0.671 > 0.453
Average MCC ± 95% Confidence Intervals 0.671 ± 0.018 > 0.504 ± 0.020
Sensitivity 0.592 > 0.449
Positive Predictive Value 0.760 > 0.458
Total TP 30335 > 22979
Total TN 108064642 > 108054370
Total FP 11237 < 30435
Total FP CONTRA 1691 < 4084
Total FP INCONS 7900 < 23135
Total FP COMP 1646 < 3216
Total FN 20869 < 28225
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of RNAalifold(20) and Afold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(20) and Afold).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for RNAalifold(20) and Afold).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(20) and Afold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(20) and Afold).

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Performance of RNAalifold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(20)

Total Base Pair Counts
Total TP 30335
Total TN 108064642
Total FP 11237
Total FP CONTRA 1691
Total FP INCONS 7900
Total FP COMP 1646
Total FN 20869
Total Scores
MCC 0.671
Average MCC ± 95% Confidence Intervals 0.671 ± 0.018
Sensitivity 0.592
Positive Predictive Value 0.760
Nr of predictions 228

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2. Individual counts for RNAalifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.58 0.45 0.75 44 47836 15 1 14 0 53
ASE_00005 0.64 0.49 0.85 57 57903 10 1 9 0 60
ASE_00006 0.68 0.56 0.83 52 47523 12 0 11 1 41
ASE_00007 0.75 0.63 0.90 69 59608 8 1 7 0 41
ASE_00012 0.55 0.45 0.68 55 73839 30 1 25 4 68
ASE_00020 0.49 0.35 0.70 44 73857 20 7 12 1 82
ASE_00021 0.54 0.41 0.73 65 104107 28 4 20 4 95
ASE_00028 0.76 0.62 0.93 78 84582 10 1 5 4 48
ASE_00037 0.72 0.62 0.83 68 59258 18 0 14 4 42
ASE_00038 0.65 0.51 0.81 52 53564 12 1 11 0 49
ASE_00040 0.69 0.55 0.86 73 78918 13 1 11 1 60
ASE_00041 0.73 0.65 0.82 70 57545 15 0 15 0 38
ASE_00042 0.52 0.39 0.70 57 90018 25 1 24 0 88
ASE_00044 0.74 0.63 0.88 66 54540 9 1 8 0 39
ASE_00064 0.72 0.61 0.84 54 45387 13 0 10 3 35
ASE_00068 0.73 0.55 0.96 47 37626 2 2 0 0 38
ASE_00074 0.72 0.61 0.86 72 67812 14 0 12 2 47
ASE_00075 0.55 0.40 0.76 65 108725 27 3 18 6 97
ASE_00077 0.79 0.65 0.97 56 45092 5 1 1 3 30
ASE_00078 0.77 0.70 0.84 58 43002 11 3 8 0 25
ASE_00080 0.43 0.32 0.59 39 71565 27 3 24 0 84
ASE_00081 0.72 0.56 0.93 54 49712 4 0 4 0 43
ASE_00082 0.49 0.34 0.72 39 70446 21 1 14 6 77
ASE_00083 0.77 0.62 0.96 68 62410 4 2 1 1 42
ASE_00084 0.61 0.51 0.75 50 53561 17 4 13 0 49
ASE_00087 0.64 0.44 0.93 64 88341 5 0 5 0 80
ASE_00090 0.72 0.55 0.93 56 55551 4 0 4 0 45
ASE_00092 0.73 0.58 0.93 65 63476 6 1 4 1 48
ASE_00104 0.66 0.54 0.81 64 64182 15 2 13 0 55
ASE_00115 0.73 0.60 0.88 61 54546 12 1 7 4 40
ASE_00118 0.58 0.44 0.78 45 60668 14 4 9 1 57
ASE_00119 0.57 0.41 0.80 44 62780 11 3 8 0 64
ASE_00123 0.67 0.54 0.84 46 38448 9 2 7 0 39
ASE_00125 0.70 0.55 0.89 48 39286 6 0 6 0 40
ASE_00126 0.81 0.71 0.94 58 40408 4 0 4 0 24
ASE_00128 0.74 0.60 0.91 60 53235 6 0 6 0 40
ASE_00129 0.65 0.49 0.86 54 62772 9 3 6 0 57
ASE_00131 0.62 0.48 0.80 41 39289 10 3 7 0 44
ASE_00134 0.64 0.52 0.80 49 50342 12 3 9 0 46
ASE_00135 0.49 0.38 0.63 41 63125 24 1 23 0 68
ASE_00136 0.80 0.67 0.95 62 48140 3 2 1 0 30
ASE_00137 0.62 0.45 0.85 44 48464 9 2 6 1 54
ASE_00138 0.71 0.62 0.81 50 40408 15 0 12 3 31
ASE_00140 0.69 0.51 0.93 64 70807 5 1 4 0 61
ASE_00146 0.78 0.67 0.91 83 70785 11 1 7 3 41
ASE_00153 0.41 0.34 0.50 25 57580 28 1 24 3 48
ASE_00163 0.64 0.52 0.79 48 53240 13 4 9 0 45
ASE_00165 0.66 0.48 0.91 48 52922 6 1 4 1 53
ASE_00170 0.62 0.53 0.74 49 48762 18 4 13 1 44
ASE_00171 0.60 0.46 0.80 43 48462 11 4 7 0 51
ASE_00172 0.80 0.67 0.95 71 58921 7 3 1 3 35
ASE_00174 0.56 0.41 0.75 45 61015 15 2 13 0 64
ASE_00175 0.61 0.50 0.74 54 59958 19 3 16 0 53
ASE_00179 0.78 0.68 0.90 57 44190 6 2 4 0 27
ASE_00180 0.66 0.53 0.82 53 51295 12 4 8 0 47
ASE_00181 0.58 0.42 0.80 45 57574 12 3 8 1 61
ASE_00182 0.44 0.29 0.68 39 84198 18 4 14 0 97
ASE_00183 0.55 0.39 0.79 44 61369 12 4 8 0 69
ASE_00185 0.70 0.51 0.97 65 73469 2 1 1 0 63
ASE_00186 0.62 0.49 0.79 65 78921 19 2 15 2 67
ASE_00190 0.64 0.52 0.78 47 45391 17 0 13 4 43
ASE_00197 0.50 0.37 0.69 53 89176 24 0 24 0 92
ASE_00198 0.68 0.54 0.86 55 52586 9 1 8 0 47
ASE_00203 0.65 0.51 0.83 49 46606 10 2 8 0 47
ASE_00212 0.64 0.49 0.84 73 93874 17 0 14 3 75
ASE_00214 0.69 0.51 0.93 53 56223 5 0 4 1 50
ASE_00215 0.69 0.49 0.96 49 48465 2 2 0 0 50
ASE_00216 0.77 0.61 0.96 50 39288 3 0 2 1 32
ASE_00217 0.78 0.67 0.91 60 40404 7 2 4 1 30
ASE_00221 0.78 0.68 0.89 80 64530 10 1 9 0 37
ASE_00228 0.70 0.62 0.79 53 46904 15 5 9 1 33
ASE_00229 0.74 0.61 0.90 53 42427 8 0 6 2 34
ASE_00231 0.59 0.46 0.76 44 47837 18 0 14 4 52
ASE_00232 0.78 0.65 0.93 55 38444 4 0 4 0 29
ASE_00234 0.50 0.32 0.77 41 75413 12 3 9 0 88
ASE_00238 0.59 0.46 0.78 52 64194 16 0 15 1 62
ASE_00241 0.70 0.60 0.83 52 43893 14 3 8 3 35
ASE_00254 0.79 0.68 0.92 56 36795 6 0 5 1 26
ASE_00255 0.49 0.40 0.60 52 74605 35 1 33 1 78
ASE_00257 0.62 0.52 0.75 50 50973 17 3 14 0 47
ASE_00263 0.61 0.44 0.85 53 70438 9 1 8 0 67
ASE_00267 0.82 0.75 0.89 66 45076 9 3 5 1 22
ASE_00270 0.30 0.18 0.50 23 72344 25 1 22 2 105
ASE_00274 0.50 0.36 0.69 37 55557 17 5 12 0 66
ASE_00277 0.48 0.37 0.62 34 48150 21 4 17 0 57
ASE_00279 0.74 0.60 0.91 61 53234 6 0 6 0 40
ASE_00280 0.68 0.55 0.84 54 51939 10 1 9 0 44
ASE_00282 0.59 0.43 0.82 54 77749 12 3 9 0 73
ASE_00283 0.65 0.51 0.83 55 61710 11 2 9 0 52
ASE_00284 0.70 0.53 0.92 57 58249 5 0 5 0 51
ASE_00285 0.63 0.48 0.84 58 68937 11 2 9 0 64
ASE_00286 0.79 0.66 0.94 61 46600 4 0 4 0 31
ASE_00287 0.63 0.48 0.84 49 54888 9 1 8 0 54
ASE_00292 0.69 0.56 0.85 77 81719 14 3 11 0 61
ASE_00294 0.64 0.47 0.87 81 114388 14 2 10 2 90
ASE_00296 0.62 0.47 0.81 68 91722 16 3 13 0 77
ASE_00297 0.69 0.52 0.93 51 52920 7 0 4 3 47
ASE_00298 0.65 0.51 0.83 58 67458 12 5 7 0 55
ASE_00328 0.71 0.64 0.77 72 72678 27 5 16 6 40
ASE_00332 0.76 0.63 0.92 87 81715 8 0 8 0 51
ASE_00340 0.65 0.55 0.76 47 45994 15 7 8 0 38
ASE_00342 0.72 0.61 0.86 70 62400 14 3 8 3 45
ASE_00361 0.69 0.51 0.93 65 75396 5 1 4 0 62
ASE_00362 0.75 0.63 0.90 57 48142 6 2 4 0 34
ASE_00363 0.72 0.63 0.83 59 51289 12 2 10 0 35
ASE_00364 0.55 0.39 0.77 41 54232 12 1 11 0 64
ASE_00366 0.51 0.37 0.71 36 58602 16 1 14 1 62
ASE_00367 0.78 0.65 0.93 56 43011 4 0 4 0 30
ASE_00369 0.69 0.57 0.84 61 55872 12 3 9 0 46
ASE_00370 0.66 0.51 0.84 43 41854 8 0 8 0 41
ASE_00372 0.74 0.62 0.87 62 51932 9 0 9 0 38
ASE_00374 0.74 0.59 0.93 52 44794 4 0 4 0 36
ASE_00376 0.73 0.58 0.92 61 56887 6 0 5 1 44
ASE_00379 0.75 0.62 0.90 55 45995 6 2 4 0 34
ASE_00382 0.70 0.60 0.82 50 41844 11 2 9 0 34
ASE_00383 0.77 0.66 0.90 69 54538 11 3 5 3 36
ASE_00384 0.74 0.59 0.93 54 48458 4 0 4 0 38
ASE_00386 0.75 0.64 0.90 61 50335 7 2 5 0 35
ASE_00387 0.74 0.61 0.90 63 55875 7 0 7 0 41
ASE_00388 0.73 0.61 0.87 54 45691 10 1 7 2 35
ASE_00390 0.73 0.60 0.88 51 42137 7 0 7 0 34
ASE_00393 0.67 0.58 0.78 54 47826 16 2 13 1 39
ASE_00394 0.68 0.56 0.83 52 46908 11 3 8 0 41
ASE_00395 0.87 0.79 0.97 66 41548 2 0 2 0 18
ASE_00396 0.74 0.63 0.88 52 41557 7 0 7 0 31
ASE_00397 0.78 0.64 0.96 67 54545 5 3 0 2 38
ASE_00398 0.63 0.48 0.82 50 55884 12 3 8 1 54
ASE_00400 0.78 0.66 0.92 70 57894 11 3 3 5 36
ASE_00401 0.54 0.37 0.81 46 76971 11 3 8 0 80
ASE_00402 0.78 0.66 0.93 56 42426 4 0 4 0 29
ASE_00403 0.69 0.51 0.93 55 55886 4 0 4 0 52
ASE_00404 0.77 0.64 0.93 54 43013 5 1 3 1 31
ASE_00411 0.64 0.52 0.79 46 49397 12 7 5 0 43
ASE_00413 0.60 0.52 0.70 42 44491 21 4 14 3 39
ASE_00415 0.55 0.40 0.76 41 54892 14 0 13 1 62
ASE_00416 0.70 0.60 0.83 76 77329 16 2 14 0 51
ASE_00419 0.56 0.40 0.79 41 54894 11 2 9 0 62
ASE_00422 0.69 0.59 0.82 55 46904 13 0 12 1 39
ASE_00428 0.66 0.54 0.80 68 76551 17 1 16 0 57
ASE_00430 0.69 0.57 0.83 55 46905 12 0 11 1 42
ASE_00437 0.45 0.36 0.58 48 79318 35 2 33 0 87
ASE_00441 0.55 0.38 0.80 43 64207 15 0 11 4 69
ASE_00448 0.77 0.70 0.86 78 64170 13 1 12 0 34
ASE_00451 0.70 0.56 0.86 70 70795 11 3 8 0 55
CRW_00024 0.87 0.84 0.90 385 1085172 61 7 37 17 73
CRW_00048 0.83 0.80 0.86 374 1170779 75 11 51 13 96
CRW_00054 0.84 0.82 0.87 372 1107390 68 12 42 14 84
CRW_00059 0.81 0.76 0.86 361 1172324 71 11 50 10 112
CRW_00061 0.85 0.80 0.90 382 1181529 55 14 28 13 94
CRW_00068 0.86 0.83 0.89 381 1108875 61 12 37 12 76
CRW_00096 0.85 0.81 0.90 376 1178461 63 6 37 20 89
CRW_00140 0.84 0.82 0.87 380 1135841 71 13 44 14 83
CRW_00141 0.82 0.78 0.87 371 1201597 71 12 45 14 105
CRW_00150 0.84 0.80 0.88 372 1152500 62 12 37 13 94
CRW_00152 0.79 0.75 0.82 355 1179984 91 17 60 14 116
CRW_00166 0.83 0.79 0.88 368 1190777 71 7 44 20 100
CRW_00173 0.77 0.75 0.80 332 1082242 94 12 70 12 113
CRW_00177 0.80 0.76 0.84 358 1178455 78 13 54 11 115
CRW_00196 0.82 0.79 0.86 373 1207803 68 15 44 9 102
CRW_00230 0.83 0.79 0.88 378 1198495 67 12 41 14 100
CRW_00245 0.86 0.83 0.89 378 1105903 56 14 33 9 75
CRW_00248 0.79 0.75 0.83 364 1218705 87 17 55 15 120
CRW_00250 0.83 0.78 0.88 373 1198502 61 12 39 10 105
CRW_00256 0.82 0.78 0.87 363 1192322 68 14 41 13 105
CRW_00270 0.85 0.83 0.88 376 1111859 66 12 39 15 79
CRW_00271 0.82 0.79 0.87 363 1122332 69 11 45 13 99
CRW_00273 0.84 0.81 0.87 360 1085185 68 13 43 12 86
CRW_00275 0.84 0.81 0.87 368 1114849 68 12 42 14 89
CRW_00277 0.82 0.79 0.85 359 1110374 76 14 48 14 94
CRW_00278 0.82 0.78 0.86 349 1129851 72 10 46 16 101
CRW_00279 0.81 0.78 0.85 360 1179994 80 12 50 18 104
CRW_00280 0.83 0.79 0.87 360 1117845 71 12 43 16 93
CRW_00281 0.82 0.78 0.85 363 1144916 75 12 50 13 101
CRW_00284 0.84 0.80 0.89 363 1131350 62 12 35 15 93
CRW_00285 0.83 0.79 0.88 364 1117844 66 13 39 14 94
CRW_00289 0.81 0.76 0.86 361 1189232 70 13 47 10 115
CRW_00298 0.43 0.38 0.49 187 1620517 224 43 153 28 307
CRW_00301 0.42 0.37 0.48 192 1762101 229 37 173 19 327
CRW_00310 0.46 0.39 0.55 204 1805579 190 29 138 23 317
CRW_00326 0.41 0.35 0.47 178 1627730 219 36 166 17 324
CRW_00330 0.40 0.35 0.47 182 1988624 243 35 174 34 335
CRW_00332 0.39 0.34 0.43 164 1769642 239 35 180 24 313
CRW_00333 0.34 0.29 0.40 150 1892114 241 34 187 20 364
CRW_00345 0.43 0.38 0.48 189 1586477 222 39 166 17 309
CRW_00348 0.43 0.38 0.48 190 1615106 228 41 166 21 313
CRW_00358 0.43 0.38 0.49 192 1674972 227 34 167 26 315
CRW_00366 0.39 0.34 0.45 166 1579381 248 30 176 42 316
CRW_00370 0.52 0.47 0.57 240 1640342 204 34 150 20 266
CRW_00371 0.43 0.38 0.49 187 1611527 222 27 169 26 309
CRW_00372 0.40 0.35 0.46 174 1625925 228 37 170 21 324
CRW_00379 0.40 0.34 0.47 179 2126574 228 31 169 28 355
CRW_00386 0.44 0.37 0.51 193 1750879 199 35 149 15 322
CRW_00403 0.39 0.37 0.42 170 1606127 272 38 193 41 294
CRW_00411 0.43 0.39 0.48 191 1615105 227 43 164 20 305
CRW_00414 0.38 0.35 0.41 171 1665811 266 36 207 23 324
CRW_00466 0.84 0.81 0.86 373 1116333 74 11 48 15 85
CRW_00589 0.86 0.81 0.91 361 1094062 61 7 30 24 84
CRW_00590 0.84 0.79 0.89 358 1119354 70 6 38 26 94
CRW_00591 0.87 0.83 0.91 368 1098500 61 9 26 26 78
CRW_00598 0.42 0.38 0.47 187 1665825 229 39 174 16 304
CRW_00758 0.48 0.43 0.53 210 1640373 205 34 149 22 273
CRW_00759 0.42 0.38 0.48 182 1636762 232 39 162 31 299
CRW_00760 0.43 0.37 0.50 179 1638594 209 38 144 27 307
CRW_00772 0.78 0.74 0.83 298 945642 94 6 54 34 106
CRW_00789 0.82 0.78 0.87 348 1137388 80 6 44 30 99
CRW_00795 0.74 0.70 0.79 276 1152572 131 10 63 58 118
CRW_00849 0.78 0.74 0.82 350 1117832 97 13 65 19 120
CRW_01153 0.47 0.42 0.53 210 1606133 216 27 158 31 293
CRW_01171 0.44 0.38 0.50 193 1593619 210 32 161 17 313
CRW_01300 0.52 0.45 0.59 231 1693331 174 31 127 16 284
PDB_00571 0.87 0.80 0.95 20 3300 1 1 0 0 5
PDB_00703 0.78 0.71 0.86 353 1073436 80 10 46 24 142
PDB_00828 0.84 0.70 1.00 19 2466 0 0 0 0 8
PDB_00829 0.86 0.75 1.00 18 2260 0 0 0 0 6
PDB_00854 0.75 0.65 0.86 347 1500373 97 7 51 39 188
PDB_01088 0.73 0.62 0.86 341 1471072 93 2 55 36 206
PDB_01103 0.75 0.65 0.87 364 1606111 77 8 45 24 198
PDB_01105 0.76 0.67 0.87 360 1433555 85 3 53 29 180
PDB_01120 0.72 0.65 0.80 341 1204702 101 13 72 16 186
PDB_01273 0.78 0.71 0.86 347 1117857 83 8 48 27 144
RFA_00599 0.75 0.65 0.87 72 101392 18 0 11 7 39
RFA_00601 0.75 0.66 0.85 75 99147 17 0 13 4 39
RFA_00602 0.65 0.54 0.78 63 101394 21 0 18 3 53
TMR_00038 0.65 0.53 0.81 58 71181 14 4 10 0 52
TMR_00046 0.56 0.49 0.64 47 62761 28 4 23 1 49
TMR_00048 0.64 0.52 0.80 49 64919 13 5 7 1 46
TMR_00458 0.54 0.46 0.64 43 63479 28 8 16 4 50
TMR_00568 0.73 0.67 0.80 66 60644 22 3 13 6 33

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Performance of Afold - scored lower in this pairwise comparison

1. Total counts & total scores for Afold

Total Base Pair Counts
Total TP 22979
Total TN 108054370
Total FP 30435
Total FP CONTRA 4084
Total FP INCONS 23135
Total FP COMP 3216
Total FN 28225
Total Scores
MCC 0.453
Average MCC ± 95% Confidence Intervals 0.504 ± 0.020
Sensitivity 0.449
Positive Predictive Value 0.458
Nr of predictions 228

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2. Individual counts for Afold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.51 0.52 0.51 50 47797 49 10 38 1 47
ASE_00005 0.61 0.56 0.66 66 57870 39 0 34 5 51
ASE_00006 0.66 0.67 0.65 62 47491 36 7 26 3 31
ASE_00007 0.56 0.53 0.59 58 59586 45 1 40 4 52
ASE_00012 0.41 0.39 0.43 48 73808 72 1 63 8 75
ASE_00020 0.57 0.54 0.60 68 73807 46 6 39 1 58
ASE_00021 0.54 0.51 0.59 81 104058 66 7 50 9 79
ASE_00028 0.58 0.56 0.61 70 84551 54 4 41 9 56
ASE_00037 0.34 0.32 0.37 35 59245 63 0 60 3 75
ASE_00038 0.53 0.52 0.54 53 53529 48 4 42 2 48
ASE_00040 0.50 0.47 0.53 63 78883 63 5 52 6 70
ASE_00041 0.53 0.51 0.55 55 57530 51 2 43 6 53
ASE_00042 0.44 0.42 0.47 61 89969 73 3 67 3 84
ASE_00044 0.74 0.70 0.78 74 54520 26 3 18 5 31
ASE_00064 0.43 0.43 0.44 38 45364 54 5 44 5 51
ASE_00068 0.33 0.32 0.36 27 37599 50 2 47 1 58
ASE_00074 0.48 0.47 0.50 56 67784 57 7 49 1 63
ASE_00075 0.65 0.59 0.72 95 108679 46 3 34 9 67
ASE_00077 0.52 0.51 0.54 44 45068 39 6 32 1 42
ASE_00078 0.67 0.67 0.67 56 42988 32 5 22 5 27
ASE_00080 0.50 0.48 0.52 59 71518 59 3 51 5 64
ASE_00081 0.46 0.45 0.46 44 49675 53 5 46 2 53
ASE_00082 0.57 0.54 0.61 63 70396 51 1 40 10 53
ASE_00083 0.71 0.67 0.76 74 62383 32 1 23 8 36
ASE_00084 0.72 0.71 0.73 70 53532 30 6 20 4 29
ASE_00087 0.56 0.51 0.61 74 88288 54 5 43 6 70
ASE_00090 0.46 0.47 0.47 47 55510 59 6 48 5 54
ASE_00092 0.68 0.65 0.72 73 63444 35 3 26 6 40
ASE_00104 0.53 0.50 0.56 60 64153 49 8 40 1 59
ASE_00115 0.55 0.54 0.56 55 54517 51 1 42 8 46
ASE_00118 0.38 0.38 0.39 39 60625 64 5 57 2 63
ASE_00119 0.63 0.60 0.67 65 62738 35 1 31 3 43
ASE_00123 0.44 0.42 0.46 36 38425 48 3 39 6 49
ASE_00125 0.64 0.63 0.65 55 39255 32 4 26 2 33
ASE_00126 0.74 0.74 0.73 61 40387 27 3 19 5 21
ASE_00128 0.74 0.72 0.77 72 53207 30 2 20 8 28
ASE_00129 0.77 0.74 0.80 82 62732 26 3 18 5 29
ASE_00131 0.62 0.55 0.70 47 39273 31 0 20 11 38
ASE_00134 0.43 0.42 0.44 40 50313 54 7 43 4 55
ASE_00135 0.45 0.44 0.45 48 63084 63 8 50 5 61
ASE_00136 0.69 0.65 0.72 60 48122 28 3 20 5 32
ASE_00137 0.44 0.43 0.45 42 48423 53 4 47 2 56
ASE_00138 0.51 0.49 0.53 40 40395 36 4 31 1 41
ASE_00140 0.62 0.57 0.67 71 70770 38 6 29 3 54
ASE_00146 0.55 0.52 0.59 64 70768 50 2 42 6 60
ASE_00153 0.66 0.67 0.65 49 57555 68 2 24 42 24
ASE_00163 0.64 0.63 0.66 59 53211 43 4 27 12 34
ASE_00165 0.64 0.60 0.67 61 52884 31 5 25 1 40
ASE_00170 0.70 0.68 0.72 63 48740 27 2 23 2 30
ASE_00171 0.70 0.69 0.71 65 48425 28 5 21 2 29
ASE_00172 0.62 0.61 0.63 65 58893 41 8 30 3 41
ASE_00174 0.59 0.57 0.62 62 60975 42 6 32 4 47
ASE_00175 0.59 0.59 0.59 63 59925 45 7 36 2 44
ASE_00179 0.64 0.65 0.62 55 44164 35 7 27 1 29
ASE_00180 0.71 0.69 0.74 69 51267 31 2 22 7 31
ASE_00181 0.54 0.53 0.55 56 57528 52 3 43 6 50
ASE_00182 0.60 0.58 0.62 79 84128 49 6 42 1 57
ASE_00183 0.71 0.70 0.72 79 61316 35 2 28 5 34
ASE_00185 0.72 0.70 0.74 89 73416 38 6 25 7 39
ASE_00186 0.73 0.69 0.78 91 78887 30 3 22 5 41
ASE_00190 0.49 0.46 0.52 41 45372 44 7 31 6 49
ASE_00197 0.49 0.46 0.52 67 89123 66 4 59 3 78
ASE_00198 0.61 0.59 0.64 60 52556 40 6 28 6 42
ASE_00203 0.70 0.69 0.72 66 46573 26 7 19 0 30
ASE_00212 0.70 0.67 0.74 99 93827 39 3 32 4 49
ASE_00214 0.72 0.72 0.73 74 56178 36 4 24 8 29
ASE_00215 0.54 0.51 0.57 50 48429 39 4 33 2 49
ASE_00216 0.67 0.68 0.66 56 39255 31 9 20 2 26
ASE_00217 0.40 0.37 0.45 33 40396 48 3 38 7 57
ASE_00221 0.49 0.45 0.54 53 64522 48 3 42 3 64
ASE_00228 0.52 0.53 0.50 46 46879 46 14 32 0 40
ASE_00229 0.61 0.61 0.62 53 42400 33 8 25 0 34
ASE_00231 0.65 0.65 0.65 62 47800 33 5 28 0 34
ASE_00232 0.63 0.64 0.61 54 38415 37 10 24 3 30
ASE_00234 0.58 0.53 0.62 69 75355 47 3 39 5 60
ASE_00238 0.59 0.59 0.60 67 64150 50 2 42 6 47
ASE_00241 0.49 0.49 0.49 43 43868 47 7 38 2 44
ASE_00254 0.49 0.46 0.52 38 36783 39 4 31 4 44
ASE_00255 0.64 0.62 0.66 80 74570 45 7 34 4 50
ASE_00257 0.55 0.55 0.55 53 50944 47 4 39 4 44
ASE_00263 0.62 0.63 0.62 76 70377 49 5 42 2 44
ASE_00267 0.32 0.31 0.34 27 45070 62 5 48 9 61
ASE_00270 0.76 0.73 0.80 94 72272 29 4 20 5 34
ASE_00274 0.45 0.44 0.46 45 55513 54 10 43 1 58
ASE_00277 0.38 0.38 0.38 35 48112 61 9 49 3 56
ASE_00279 0.68 0.66 0.71 67 53206 35 3 25 7 34
ASE_00280 0.36 0.36 0.37 35 51909 65 4 55 6 63
ASE_00282 0.56 0.55 0.57 70 77693 58 5 47 6 57
ASE_00283 0.75 0.73 0.77 78 61675 30 3 20 7 29
ASE_00284 0.62 0.60 0.64 65 58210 44 4 32 8 43
ASE_00285 0.75 0.70 0.80 86 68899 28 3 18 7 36
ASE_00286 0.43 0.42 0.43 39 46574 63 5 47 11 53
ASE_00287 0.59 0.55 0.63 57 54856 39 2 31 6 46
ASE_00292 0.62 0.58 0.66 80 81689 43 2 39 2 58
ASE_00294 0.74 0.68 0.80 117 114335 32 2 27 3 54
ASE_00296 0.25 0.24 0.27 35 91676 98 8 87 3 110
ASE_00297 0.50 0.50 0.51 49 52878 53 4 44 5 49
ASE_00298 0.28 0.27 0.29 31 67420 79 9 68 2 82
ASE_00328 0.40 0.41 0.40 46 72656 75 3 66 6 66
ASE_00332 0.56 0.54 0.59 75 81682 55 2 51 2 63
ASE_00340 0.76 0.73 0.78 62 45977 26 6 11 9 23
ASE_00342 0.57 0.54 0.60 62 62378 41 5 36 0 53
ASE_00361 0.51 0.49 0.53 62 75349 59 7 48 4 65
ASE_00362 0.61 0.60 0.61 55 48115 39 6 29 4 36
ASE_00363 0.53 0.54 0.53 51 51263 47 5 41 1 43
ASE_00364 0.42 0.42 0.43 44 54182 63 4 55 4 61
ASE_00366 0.54 0.56 0.53 55 58549 52 10 39 3 43
ASE_00367 0.28 0.29 0.27 25 42979 68 8 59 1 61
ASE_00369 0.56 0.55 0.58 59 55843 44 4 39 1 48
ASE_00370 0.63 0.63 0.62 53 41820 33 7 25 1 31
ASE_00372 0.63 0.62 0.65 62 51907 39 6 28 5 38
ASE_00374 0.53 0.52 0.54 46 44765 40 8 31 1 42
ASE_00376 0.48 0.46 0.50 48 56857 52 4 44 4 57
ASE_00379 0.57 0.55 0.60 49 45974 41 3 30 8 40
ASE_00382 0.49 0.49 0.50 41 41823 45 6 35 4 43
ASE_00383 0.58 0.55 0.62 58 54521 40 3 33 4 47
ASE_00384 0.41 0.39 0.43 36 48432 58 2 46 10 56
ASE_00386 0.65 0.65 0.65 62 50307 41 3 31 7 34
ASE_00387 0.43 0.43 0.43 45 55841 59 6 53 0 59
ASE_00388 0.43 0.42 0.44 37 45669 53 3 44 6 52
ASE_00390 0.44 0.42 0.47 36 42118 52 6 35 11 49
ASE_00393 0.37 0.35 0.39 33 47811 58 2 49 7 60
ASE_00394 0.69 0.68 0.70 63 46881 29 5 22 2 30
ASE_00395 0.65 0.63 0.68 53 41538 35 1 24 10 31
ASE_00396 0.16 0.16 0.16 13 41535 71 2 66 3 70
ASE_00397 0.54 0.54 0.54 57 54510 51 4 44 3 48
ASE_00398 0.61 0.58 0.65 60 55852 37 1 32 4 44
ASE_00400 0.53 0.53 0.54 56 57866 51 7 41 3 50
ASE_00401 0.52 0.53 0.51 67 76897 65 13 51 1 59
ASE_00402 0.41 0.40 0.43 34 42406 52 7 39 6 51
ASE_00403 0.44 0.42 0.47 45 55849 55 4 47 4 62
ASE_00404 0.55 0.54 0.57 46 42990 43 0 35 8 39
ASE_00411 0.35 0.35 0.35 31 49366 63 7 51 5 58
ASE_00413 0.55 0.58 0.52 47 44461 44 13 30 1 34
ASE_00415 0.51 0.51 0.51 53 54843 53 7 43 3 50
ASE_00416 0.65 0.61 0.68 78 77307 43 0 36 7 49
ASE_00419 0.75 0.73 0.78 75 54850 26 5 16 5 28
ASE_00422 0.44 0.44 0.45 41 46880 56 5 45 6 53
ASE_00428 0.51 0.50 0.53 62 76520 58 5 49 4 63
ASE_00430 0.64 0.63 0.66 61 46878 39 5 27 7 36
ASE_00437 0.42 0.39 0.46 53 79285 64 4 59 1 82
ASE_00441 0.77 0.72 0.83 81 64163 30 1 16 13 31
ASE_00448 0.22 0.22 0.23 25 64150 91 6 80 5 87
ASE_00451 0.61 0.57 0.66 71 70768 40 2 35 3 54
CRW_00024 0.78 0.77 0.79 351 1085158 132 17 75 40 107
CRW_00048 0.49 0.49 0.50 228 1170758 252 20 209 23 242
CRW_00054 0.46 0.46 0.46 208 1107368 260 31 209 20 248
CRW_00059 0.52 0.51 0.53 240 1172289 233 26 191 16 233
CRW_00061 0.55 0.54 0.55 259 1181483 231 27 184 20 217
CRW_00068 0.49 0.49 0.50 226 1108849 247 24 206 17 231
CRW_00096 0.46 0.46 0.47 214 1178420 264 32 214 18 251
CRW_00140 0.64 0.63 0.64 291 1135826 182 20 141 21 172
CRW_00141 0.59 0.58 0.60 274 1201566 212 26 159 27 202
CRW_00150 0.42 0.41 0.42 193 1152465 282 35 228 19 273
CRW_00152 0.64 0.62 0.65 293 1179965 180 30 128 22 178
CRW_00166 0.54 0.53 0.55 248 1190745 226 28 175 23 220
CRW_00173 0.29 0.29 0.29 127 1082216 323 37 276 10 318
CRW_00177 0.44 0.43 0.45 203 1178433 259 22 222 15 270
CRW_00196 0.47 0.46 0.48 220 1207772 267 24 219 24 255
CRW_00230 0.57 0.56 0.58 266 1198467 216 21 172 23 212
CRW_00245 0.38 0.38 0.38 172 1105880 289 44 232 13 281
CRW_00248 0.57 0.57 0.58 274 1218666 234 21 180 33 210
CRW_00250 0.44 0.44 0.45 210 1198459 274 34 223 17 268
CRW_00256 0.41 0.40 0.42 188 1192291 278 39 222 17 280
CRW_00270 0.44 0.43 0.45 196 1111850 260 40 200 20 259
CRW_00271 0.51 0.50 0.51 231 1122302 237 43 175 19 231
CRW_00273 0.59 0.58 0.60 258 1085174 195 26 143 26 188
CRW_00275 0.47 0.47 0.48 213 1114826 258 28 204 26 244
CRW_00277 0.38 0.38 0.38 172 1110338 300 45 240 15 281
CRW_00278 0.41 0.40 0.42 180 1129825 274 33 218 23 270
CRW_00279 0.51 0.49 0.53 229 1179985 227 29 173 25 235
CRW_00280 0.51 0.50 0.51 227 1117817 231 28 188 15 226
CRW_00281 0.30 0.30 0.29 138 1144872 347 41 290 16 326
CRW_00284 0.28 0.27 0.28 124 1131316 337 30 290 17 332
CRW_00285 0.72 0.71 0.74 325 1117819 142 23 93 26 133
CRW_00289 0.46 0.45 0.48 214 1189204 258 34 201 23 262
CRW_00298 0.19 0.20 0.18 99 1620353 490 81 367 42 395
CRW_00301 0.30 0.31 0.30 162 1761957 428 86 298 44 357
CRW_00310 0.29 0.30 0.28 157 1805386 453 81 326 46 364
CRW_00326 0.41 0.41 0.42 204 1627621 339 47 238 54 298
CRW_00330 0.32 0.32 0.31 167 1988474 452 69 305 78 350
CRW_00332 0.18 0.20 0.17 94 1769479 492 105 343 44 383
CRW_00333 0.29 0.30 0.28 153 1891946 449 74 312 63 361
CRW_00345 0.34 0.35 0.33 175 1586340 403 71 285 47 323
CRW_00348 0.25 0.25 0.24 127 1614982 437 68 326 43 376
CRW_00358 0.36 0.36 0.35 183 1674845 391 61 276 54 324
CRW_00366 0.35 0.36 0.33 174 1579230 395 88 261 46 308
CRW_00370 0.28 0.28 0.28 143 1640248 420 77 298 45 363
CRW_00371 0.29 0.29 0.28 145 1611389 409 77 299 33 351
CRW_00372 0.36 0.36 0.35 181 1625787 378 59 279 40 317
CRW_00379 0.42 0.43 0.41 227 2126401 423 55 270 98 307
CRW_00386 0.24 0.25 0.23 129 1750683 478 83 361 34 386
CRW_00403 0.31 0.31 0.30 146 1606035 431 65 282 84 318
CRW_00411 0.34 0.34 0.34 169 1615006 381 62 266 53 327
CRW_00414 0.27 0.28 0.26 140 1665694 436 77 314 45 355
CRW_00466 0.60 0.59 0.62 268 1116330 196 21 146 29 190
CRW_00589 0.18 0.18 0.18 78 1094024 374 34 324 16 367
CRW_00590 0.36 0.36 0.37 161 1119326 290 30 239 21 291
CRW_00591 0.57 0.56 0.59 251 1098476 205 23 153 29 195
CRW_00598 0.31 0.33 0.29 162 1665675 440 88 300 52 329
CRW_00758 0.29 0.30 0.29 144 1640268 416 66 288 62 339
CRW_00759 0.22 0.22 0.21 107 1636633 462 78 327 57 374
CRW_00760 0.28 0.29 0.28 140 1638458 411 74 283 54 346
CRW_00772 0.26 0.25 0.26 103 945610 313 37 250 26 301
CRW_00789 0.36 0.36 0.36 160 1137342 302 44 240 18 287
CRW_00795 0.21 0.22 0.21 85 1152511 379 51 274 54 309
CRW_00849 0.49 0.48 0.49 227 1117798 259 23 212 24 243
CRW_01153 0.32 0.32 0.32 160 1606024 390 54 290 46 343
CRW_01171 0.32 0.33 0.31 167 1593473 402 81 284 37 339
CRW_01300 0.36 0.37 0.35 189 1693186 392 71 274 47 326
PDB_00571 -0.01 0.00 0.00 0 3302 20 5 14 1 25
PDB_00703 0.53 0.50 0.56 246 1073408 220 17 174 29 249
PDB_00828 0.88 0.78 1.00 21 2464 0 0 0 0 6
PDB_00829 0.82 0.71 0.94 17 2260 1 0 1 0 7
PDB_00854 0.55 0.53 0.56 284 1500271 276 22 201 53 251
PDB_01088 0.36 0.35 0.37 191 1470959 352 45 275 32 356
PDB_01103 0.56 0.54 0.58 306 1605999 254 32 191 31 256
PDB_01105 0.60 0.58 0.63 313 1433471 221 15 172 34 227
PDB_01120 0.46 0.43 0.49 228 1204659 250 31 210 9 299
PDB_01273 0.51 0.48 0.53 237 1117812 242 21 190 31 254
RFA_00599 0.67 0.70 0.64 78 101353 66 16 28 22 33
RFA_00601 0.09 0.11 0.08 12 99092 139 35 96 8 102
RFA_00602 0.50 0.53 0.47 62 101344 91 18 51 22 54
TMR_00038 0.25 0.25 0.25 28 71140 89 12 73 4 82
TMR_00046 0.47 0.48 0.46 46 62734 61 10 45 6 50
TMR_00048 0.35 0.37 0.34 35 64876 73 9 60 4 60
TMR_00458 0.22 0.22 0.23 20 63458 76 7 61 8 73
TMR_00568 0.57 0.57 0.58 56 60629 50 3 38 9 43

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.