Table of contents:
- Overview
- Performance Plots
- Performance of PETfold_pre2.0(20)
- scored higher in this pairwise comparison
- Performance of Carnac(20)
- scored lower in this pairwise comparison
- Compile and download dataset for PETfold_pre2.0(20) & Carnac(20) [.zip] - may take several seconds...
Overview
| Metric |
PETfold_pre2.0(20) |
|
Carnac(20) |
|---|
| MCC |
0.854 |
>
|
0.821 |
| Average MCC ± 95% Confidence Intervals |
0.858
±
0.048
|
>
|
0.825
±
0.075
|
| Sensitivity |
0.759 |
>
|
0.684 |
| Positive Predictive Value |
0.962 |
<
|
0.989 |
| Total TP |
101 |
>
|
91 |
| Total TN |
14628 |
<
|
14641 |
| Total FP |
12 |
>
|
3 |
| Total FP CONTRA |
3 |
>
|
1 |
| Total FP INCONS |
1 |
>
|
0 |
| Total FP COMP |
8 |
>
|
2 |
| Total FN |
32 |
<
|
42 |
| P-value |
0.0 |
Performance plots
-
Comparison of performance of PETfold_pre2.0(20) and Carnac(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(20)
and Carnac(20)).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(20)
and Carnac(20)).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Carnac(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(20)
and Carnac(20)).
Performance of PETfold_pre2.0(20)
- scored higher in this pairwise comparison
1. Total counts & total scores for PETfold_pre2.0(20)
| Total Base Pair Counts |
|---|
| Total TP |
101 |
| Total TN |
14628 |
| Total FP |
12 |
| Total FP CONTRA |
3 |
| Total FP INCONS |
1 |
| Total FP COMP |
8 |
| Total FN |
32 |
| Total Scores |
|---|
| MCC |
0.854 |
| Average MCC ± 95% Confidence Intervals |
0.858
±
0.048
|
| Sensitivity |
0.759 |
| Positive Predictive Value |
0.962 |
| Nr of predictions |
5 |
Performance of Carnac(20)
- scored lower in this pairwise comparison
1. Total counts & total scores for Carnac(20)
| Total Base Pair Counts |
|---|
| Total TP |
91 |
| Total TN |
14641 |
| Total FP |
3 |
| Total FP CONTRA |
1 |
| Total FP INCONS |
0 |
| Total FP COMP |
2 |
| Total FN |
42 |
| Total Scores |
|---|
| MCC |
0.821 |
| Average MCC ± 95% Confidence Intervals |
0.825
±
0.075
|
| Sensitivity |
0.684 |
| Positive Predictive Value |
0.989 |
| Nr of predictions |
5 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based
on the paper by Gardener & Giegerich, 2004.
| 
