CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of RNAwolf - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & RNAwolf [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) RNAwolf
MCC 0.854 > 0.661
Average MCC ± 95% Confidence Intervals 0.858 ± 0.048 > 0.706 ± 0.377
Sensitivity 0.759 > 0.647
Positive Predictive Value 0.962 > 0.683
Total TP 101 > 86
Total TN 14628 > 14607
Total FP 12 < 43
Total FP CONTRA 3 < 7
Total FP INCONS 1 < 33
Total FP COMP 8 > 3
Total FN 32 < 47
P-value 0.0

^top




Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and RNAwolf. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RNAwolf).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RNAwolf).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and RNAwolf. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RNAwolf).

^top





Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 101
Total TN 14628
Total FP 12
Total FP CONTRA 3
Total FP INCONS 1
Total FP COMP 8
Total FN 32
Total Scores
MCC 0.854
Average MCC ± 95% Confidence Intervals 0.858 ± 0.048
Sensitivity 0.759
Positive Predictive Value 0.962
Nr of predictions 5

^top



2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
PDB_00571 0.87 0.80 0.95 20 3300 1 1 0 0 5
PDB_00828 0.88 0.78 1.00 21 2464 2 0 0 2 6
PDB_00829 0.86 0.75 1.00 18 2260 2 0 0 2 6
PDB_01020 0.88 0.78 1.00 18 2260 3 0 0 3 5
PDB_01073 0.79 0.71 0.89 24 4344 4 2 1 1 10

^top



Performance of RNAwolf - scored lower in this pairwise comparison

1. Total counts & total scores for RNAwolf

Total Base Pair Counts
Total TP 86
Total TN 14607
Total FP 43
Total FP CONTRA 7
Total FP INCONS 33
Total FP COMP 3
Total FN 47
Total Scores
MCC 0.661
Average MCC ± 95% Confidence Intervals 0.706 ± 0.377
Sensitivity 0.647
Positive Predictive Value 0.683
Nr of predictions 5

^top



2. Individual counts for RNAwolf [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
PDB_00571 0.89 0.84 0.95 21 3299 2 1 0 1 4
PDB_00828 0.85 0.81 0.88 22 2460 3 1 2 0 5
PDB_00829 0.78 0.75 0.82 18 2256 4 1 3 0 6
PDB_01020 0.84 0.83 0.86 19 2256 5 1 2 2 4
PDB_01073 0.17 0.18 0.17 6 4336 29 3 26 0 28

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.