Table of contents:
- Overview
- Performance Plots
- Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
- Performance of RSpredict(20)
- scored lower in this pairwise comparison
- Compile and download dataset for PETfold_pre2.0(seed) & RSpredict(20) [.zip] - may take several seconds...
Overview
| Metric |
PETfold_pre2.0(seed) |
|
RSpredict(20) |
|---|
| MCC |
0.835 |
>
|
0.672 |
| Average MCC ± 95% Confidence Intervals |
0.839
±
0.049
|
>
|
0.671
±
0.248
|
| Sensitivity |
0.774 |
>
|
0.549 |
| Positive Predictive Value |
0.904 |
>
|
0.830 |
| Total TP |
103 |
>
|
73 |
| Total TN |
14619 |
<
|
14645 |
| Total FP |
16 |
<
|
17 |
| Total FP CONTRA |
10 |
>
|
6 |
| Total FP INCONS |
1 |
<
|
9 |
| Total FP COMP |
5 |
>
|
2 |
| Total FN |
30 |
<
|
60 |
| P-value |
0.0 |
Performance plots
-
Comparison of performance of PETfold_pre2.0(seed) and RSpredict(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and RSpredict(20)).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and RSpredict(20)).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and RSpredict(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and RSpredict(20)).
Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
1. Total counts & total scores for PETfold_pre2.0(seed)
| Total Base Pair Counts |
|---|
| Total TP |
103 |
| Total TN |
14619 |
| Total FP |
16 |
| Total FP CONTRA |
10 |
| Total FP INCONS |
1 |
| Total FP COMP |
5 |
| Total FN |
30 |
| Total Scores |
|---|
| MCC |
0.835 |
| Average MCC ± 95% Confidence Intervals |
0.839
±
0.049
|
| Sensitivity |
0.774 |
| Positive Predictive Value |
0.904 |
| Nr of predictions |
5 |
Performance of RSpredict(20)
- scored lower in this pairwise comparison
1. Total counts & total scores for RSpredict(20)
| Total Base Pair Counts |
|---|
| Total TP |
73 |
| Total TN |
14645 |
| Total FP |
17 |
| Total FP CONTRA |
6 |
| Total FP INCONS |
9 |
| Total FP COMP |
2 |
| Total FN |
60 |
| Total Scores |
|---|
| MCC |
0.672 |
| Average MCC ± 95% Confidence Intervals |
0.671
±
0.248
|
| Sensitivity |
0.549 |
| Positive Predictive Value |
0.830 |
| Nr of predictions |
5 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based
on the paper by Gardener & Giegerich, 2004.
| 
