CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric TurboFold(20) Mastr(seed)
MCC 0.860 > 0.000
Average MCC ± 95% Confidence Intervals 0.860 ± 0.006 > 0.000 ± 0.000
Sensitivity 0.741 > 0.000
Positive Predictive Value 1.000 > 0.000
Total TP 80 > 0
Total TN 11332 < 11412
Total FP 2 > 0
Total FP CONTRA 0 = 0
Total FP INCONS 0 = 0
Total FP COMP 2 > 0
Total FN 28 < 108
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Mastr(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for TurboFold(20) and Mastr(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Mastr(seed)).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 80
Total TN 11332
Total FP 2
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 2
Total FN 28
Total Scores
MCC 0.860
Average MCC ± 95% Confidence Intervals 0.860 ± 0.006
Sensitivity 0.741
Positive Predictive Value 1.000
Nr of predictions 4

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
PDB_00828 0.86 0.74 1.00 20 2465 0 0 0 0 7
PDB_00829 0.86 0.75 1.00 18 2260 0 0 0 0 6
PDB_01020 0.86 0.74 1.00 17 2261 1 0 0 1 6
PDB_01073 0.86 0.74 1.00 25 4346 1 0 0 1 9

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 11412
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 108
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 4

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
PDB_00828 0.00 0.00 0.00 0 2485 0 0 0 0 27
PDB_00829 0.00 0.00 0.00 0 2278 0 0 0 0 24
PDB_01020 0.00 0.00 0.00 0 2278 0 0 0 0 23
PDB_01073 0.00 0.00 0.00 0 4371 0 0 0 0 34

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.