CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of Vsfold4 - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & Vsfold4 [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) Vsfold4
MCC 0.600 > 0.316
Average MCC ± 95% Confidence Intervals 0.632 ± 0.110 > 0.301 ± 0.233
Sensitivity 0.518 > 0.298
Positive Predictive Value 0.702 > 0.347
Total TP 87 > 50
Total TN 19699 > 19679
Total FP 41 < 98
Total FP CONTRA 7 < 16
Total FP INCONS 30 < 78
Total FP COMP 4 = 4
Total FN 81 < 118
P-value 0.0

^top




Performance plots


  1. Comparison of performance of TurboFold(seed) and Vsfold4. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and Vsfold4).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for TurboFold(seed) and Vsfold4).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and Vsfold4. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and Vsfold4).

^top





Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 87
Total TN 19699
Total FP 41
Total FP CONTRA 7
Total FP INCONS 30
Total FP COMP 4
Total FN 81
Total Scores
MCC 0.600
Average MCC ± 95% Confidence Intervals 0.632 ± 0.110
Sensitivity 0.518
Positive Predictive Value 0.702
Nr of predictions 9

^top



2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00636 0.42 0.43 0.43 12 3977 16 2 14 0 16
RFA_00767 0.74 0.56 1.00 10 1881 0 0 0 0 8
RFA_00768 0.74 0.56 1.00 10 1881 0 0 0 0 8
RFA_00769 0.55 0.56 0.56 10 1935 8 3 5 0 8
RFA_00770 0.68 0.56 0.83 10 2004 5 0 2 3 8
RFA_00773 0.71 0.56 0.91 10 1942 2 1 0 1 8
RFA_00779 0.71 0.56 0.91 10 1942 1 0 1 0 8
RFA_00808 0.75 0.56 1.00 9 2007 0 0 0 0 7
RFA_00809 0.38 0.38 0.40 6 2130 9 1 8 0 10

^top



Performance of Vsfold4 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold4

Total Base Pair Counts
Total TP 50
Total TN 19679
Total FP 98
Total FP CONTRA 16
Total FP INCONS 78
Total FP COMP 4
Total FN 118
Total Scores
MCC 0.316
Average MCC ± 95% Confidence Intervals 0.301 ± 0.233
Sensitivity 0.298
Positive Predictive Value 0.347
Nr of predictions 9

^top



2. Individual counts for Vsfold4 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00636 0.58 0.57 0.59 16 3978 11 1 10 0 12
RFA_00767 -0.01 0.00 0.00 0 1878 13 1 12 0 18
RFA_00768 -0.01 0.00 0.00 0 1875 16 1 15 0 18
RFA_00769 0.50 0.50 0.50 9 1935 9 4 5 0 9
RFA_00770 -0.01 0.00 0.00 0 2003 15 2 11 2 18
RFA_00773 -0.01 0.00 0.00 0 1936 19 1 16 2 18
RFA_00779 0.65 0.56 0.77 10 1940 3 2 1 0 8
RFA_00808 0.62 0.56 0.69 9 2003 4 3 1 0 7
RFA_00809 0.40 0.38 0.43 6 2131 8 1 7 0 10

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.