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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CRWrnafold - scored higher in this pairwise comparison

  4. Performance of Cylofold - scored lower in this pairwise comparison

  5. Compile and download dataset for CRWrnafold & Cylofold [.zip] - may take several seconds...


Overview

Metric CRWrnafold Cylofold
MCC 0.470 > 0.271
Average MCC ± 95% Confidence Intervals 0.469 ± 0.202 > 0.275 ± 1.303
Sensitivity 0.474 > 0.241
Positive Predictive Value 0.468 > 0.308
Total TP 65 > 33
Total TN 60449 < 60481
Total FP 80 > 78
Total FP CONTRA 9 > 3
Total FP INCONS 65 < 71
Total FP COMP 6 > 4
Total FN 72 < 104
P-value 0.0

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Performance plots


  1. Comparison of performance of CRWrnafold and Cylofold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CRWrnafold and Cylofold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CRWrnafold and Cylofold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CRWrnafold and Cylofold).

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Performance of CRWrnafold - scored higher in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 65
Total TN 60449
Total FP 80
Total FP CONTRA 9
Total FP INCONS 65
Total FP COMP 6
Total FN 72
Total Scores
MCC 0.470
Average MCC ± 95% Confidence Intervals 0.469 ± 0.202
Sensitivity 0.474
Positive Predictive Value 0.468
Nr of predictions 2

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00408 - 0.49 0.49 0.48 35 32312 42 3 35 4 36
ASE_00429 - 0.45 0.45 0.45 30 28137 38 6 30 2 36

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Performance of Cylofold - scored lower in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 33
Total TN 60481
Total FP 78
Total FP CONTRA 3
Total FP INCONS 71
Total FP COMP 4
Total FN 104
Total Scores
MCC 0.271
Average MCC ± 95% Confidence Intervals 0.275 ± 1.303
Sensitivity 0.241
Positive Predictive Value 0.308
Nr of predictions 2

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00408 - 0.17 0.15 0.20 11 32329 45 3 42 0 60
ASE_00429 - 0.38 0.33 0.43 22 28152 33 0 29 4 44

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.