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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

  4. Performance of CentroidHomfold‑LAST - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(seed) & CentroidHomfold‑LAST [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(seed) CentroidHomfold‑LAST
MCC 0.693 > 0.675
Average MCC ± 95% Confidence Intervals 0.691 ± 0.015 > 0.670 ± 0.014
Sensitivity 0.523 > 0.507
Positive Predictive Value 0.920 > 0.899
Total TP 14948 > 14505
Total TN 16868559 < 16868669
Total FP 1616 < 2088
Total FP CONTRA 175 < 221
Total FP INCONS 1127 < 1414
Total FP COMP 314 < 453
Total FN 13639 < 14082
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of CentroidAlifold(seed) and CentroidHomfold-LAST. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(seed) and CentroidHomfold‑LAST).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for CentroidAlifold(seed) and CentroidHomfold‑LAST).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(seed) and CentroidHomfold-LAST. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(seed) and CentroidHomfold‑LAST).

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Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(seed)

Total Base Pair Counts
Total TP 14948
Total TN 16868559
Total FP 1616
Total FP CONTRA 175
Total FP INCONS 1127
Total FP COMP 314
Total FN 13639
Total Scores
MCC 0.693
Average MCC ± 95% Confidence Intervals 0.691 ± 0.015
Sensitivity 0.523
Positive Predictive Value 0.920
Nr of predictions 273

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2. Individual counts for CentroidAlifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00001 0.81 0.65 1.00 49 34142 0 0 0 0 26
ASE_00002 0.82 0.67 1.00 49 35462 0 0 0 0 24
ASE_00004 0.61 0.45 0.83 44 47842 9 0 9 0 53
ASE_00005 0.75 0.57 0.97 67 57901 2 0 2 0 50
ASE_00006 0.58 0.44 0.76 41 47532 13 0 13 0 52
ASE_00007 0.83 0.71 0.98 78 59605 2 0 2 0 32
ASE_00009 0.79 0.67 0.94 45 26058 3 0 3 0 22
ASE_00012 0.75 0.59 0.95 73 73843 7 1 3 3 50
ASE_00014 0.74 0.58 0.95 61 54221 3 0 3 0 45
ASE_00017 0.79 0.69 0.90 44 50991 5 1 4 0 20
ASE_00018 0.78 0.60 1.00 81 80520 0 0 0 0 53
ASE_00020 0.63 0.43 0.93 54 73862 4 3 1 0 72
ASE_00021 0.63 0.44 0.90 71 104117 11 2 6 3 89
ASE_00022 0.80 0.65 1.00 80 82948 5 0 0 5 44
ASE_00023 0.47 0.35 0.63 45 84184 28 8 18 2 82
ASE_00025 0.69 0.58 0.84 41 78557 8 1 7 0 30
ASE_00026 0.80 0.67 0.96 74 59608 4 0 3 1 36
ASE_00028 0.80 0.64 1.00 81 84585 3 0 0 3 45
ASE_00029 0.45 0.34 0.61 41 82961 30 4 22 4 81
ASE_00030 0.66 0.49 0.90 71 85412 8 0 8 0 74
ASE_00031 0.51 0.37 0.72 46 86672 18 0 18 0 80
ASE_00032 0.38 0.27 0.54 32 80141 30 1 26 3 86
ASE_00033 0.80 0.65 0.99 79 64900 3 1 0 2 42
ASE_00035 0.77 0.64 0.94 75 70420 8 0 5 3 43
ASE_00036 0.75 0.58 0.99 76 75778 1 1 0 0 56
ASE_00037 0.84 0.71 1.00 78 59262 1 0 0 1 32
ASE_00038 0.74 0.54 1.00 55 53573 0 0 0 0 46
ASE_00040 0.77 0.59 1.00 79 78924 2 0 0 2 54
ASE_00041 0.77 0.64 0.92 69 57555 6 0 6 0 39
ASE_00042 0.65 0.49 0.87 71 90018 11 0 11 0 74
ASE_00044 0.83 0.70 1.00 73 54542 0 0 0 0 32
ASE_00046 0.73 0.62 0.86 64 50329 10 0 10 0 39
ASE_00047 0.70 0.52 0.93 68 74232 5 0 5 0 62
ASE_00052 0.75 0.63 0.91 70 61348 8 0 7 1 42
ASE_00053 0.71 0.54 0.92 72 79323 6 3 3 0 61
ASE_00057 0.73 0.57 0.93 77 82132 6 2 4 0 57
ASE_00064 0.77 0.60 1.00 53 45398 0 0 0 0 36
ASE_00066 0.75 0.56 1.00 73 72317 1 0 0 1 57
ASE_00068 0.54 0.38 0.78 32 37634 9 0 9 0 53
ASE_00069 0.75 0.57 0.98 80 82946 3 0 2 1 60
ASE_00074 0.83 0.69 1.00 82 67814 1 0 0 1 37
ASE_00075 0.64 0.44 0.92 71 108734 11 1 5 5 91
ASE_00076 0.69 0.48 1.00 57 68208 0 0 0 0 61
ASE_00077 0.79 0.64 0.96 55 45093 2 1 1 0 31
ASE_00078 0.83 0.69 1.00 57 43014 0 0 0 0 26
ASE_00079 0.63 0.47 0.84 47 55555 9 0 9 0 53
ASE_00080 0.45 0.30 0.66 37 71575 19 1 18 0 86
ASE_00081 0.77 0.59 1.00 57 49713 0 0 0 0 40
ASE_00082 0.66 0.43 1.00 50 70450 6 0 0 6 66
ASE_00083 0.72 0.52 1.00 57 62424 0 0 0 0 53
ASE_00084 0.75 0.57 0.98 56 53571 1 1 0 0 43
ASE_00087 0.60 0.38 0.95 54 88353 3 0 3 0 90
ASE_00090 0.75 0.56 1.00 57 55554 0 0 0 0 44
ASE_00092 0.70 0.50 0.98 56 63489 1 1 0 0 57
ASE_00096 0.63 0.44 0.89 51 63489 6 0 6 0 64
ASE_00099 0.82 0.67 1.00 80 64540 0 0 0 0 40
ASE_00100 0.72 0.58 0.90 44 82166 5 1 4 0 32
ASE_00102 0.57 0.40 0.81 66 117774 15 1 14 0 100
ASE_00104 0.81 0.67 0.99 80 64180 1 0 1 0 39
ASE_00105 0.55 0.40 0.76 44 64203 14 4 10 0 67
ASE_00107 0.78 0.63 0.96 80 73070 3 0 3 0 47
ASE_00108 0.79 0.70 0.90 44 46922 5 1 4 0 19
ASE_00111 0.83 0.74 0.93 42 50041 3 1 2 0 15
ASE_00112 0.50 0.34 0.71 40 75410 16 0 16 0 76
ASE_00115 0.74 0.54 1.00 55 54560 0 0 0 0 46
ASE_00116 0.86 0.76 0.98 50 31575 1 0 1 0 16
ASE_00118 0.68 0.49 0.94 50 60673 4 1 2 1 52
ASE_00119 0.66 0.44 0.98 48 62786 1 1 0 0 60
ASE_00120 0.79 0.64 0.98 60 46910 2 0 1 1 34
ASE_00121 0.81 0.66 0.98 61 45088 1 0 1 0 31
ASE_00122 0.80 0.64 1.00 56 43309 1 0 0 1 32
ASE_00123 0.68 0.48 0.95 41 38460 2 0 2 0 44
ASE_00125 0.67 0.47 0.95 41 39297 2 0 2 0 47
ASE_00128 0.73 0.54 1.00 54 53247 0 0 0 0 46
ASE_00129 0.71 0.50 1.00 56 62779 0 0 0 0 55
ASE_00131 0.65 0.44 0.97 37 39302 1 1 0 0 48
ASE_00132 0.76 0.59 0.98 56 50346 1 1 0 0 39
ASE_00134 0.69 0.54 0.89 51 50346 6 0 6 0 44
ASE_00135 0.53 0.39 0.74 42 63133 15 0 15 0 67
ASE_00136 0.75 0.59 0.95 54 48148 3 0 3 0 38
ASE_00137 0.70 0.53 0.93 52 48460 4 0 4 0 46
ASE_00138 0.79 0.63 1.00 51 40419 0 0 0 0 30
ASE_00139 0.73 0.54 1.00 56 54229 0 0 0 0 48
ASE_00140 0.64 0.43 0.95 54 70819 3 3 0 0 71
ASE_00142 0.77 0.61 0.97 75 67084 4 0 2 2 47
ASE_00145 0.77 0.59 1.00 66 70059 0 0 0 0 45
ASE_00146 0.78 0.62 0.97 77 70797 2 0 2 0 47
ASE_00148 0.62 0.41 0.95 63 112509 3 0 3 0 91
ASE_00151 0.80 0.70 0.92 69 51928 6 5 1 0 29
ASE_00153 0.67 0.53 0.85 39 57584 7 1 6 0 34
ASE_00154 0.75 0.59 0.95 63 65275 3 0 3 0 44
ASE_00155 0.68 0.46 1.00 66 93462 0 0 0 0 76
ASE_00163 0.77 0.59 1.00 55 53246 0 0 0 0 38
ASE_00165 0.69 0.50 0.94 51 52921 4 1 2 1 50
ASE_00168 0.79 0.69 0.90 44 60677 5 1 4 0 20
ASE_00169 0.65 0.48 0.88 51 57233 7 1 6 0 56
ASE_00170 0.78 0.60 1.00 56 48772 0 0 0 0 37
ASE_00171 0.76 0.59 1.00 55 48461 1 0 0 1 39
ASE_00172 0.72 0.53 0.98 56 58939 1 1 0 0 50
ASE_00174 0.60 0.43 0.82 47 61018 10 1 9 0 62
ASE_00175 0.71 0.51 0.98 55 59975 1 1 0 0 52
ASE_00176 0.71 0.50 1.00 55 59976 0 0 0 0 55
ASE_00179 0.79 0.63 0.98 53 44199 2 0 1 1 31
ASE_00180 0.73 0.54 0.98 54 51305 1 1 0 0 46
ASE_00181 0.71 0.52 0.96 55 57573 3 2 0 1 51
ASE_00182 0.61 0.40 0.95 54 84198 3 0 3 0 82
ASE_00184 0.75 0.56 1.00 57 54558 0 0 0 0 45
ASE_00185 0.64 0.41 0.98 53 73482 1 1 0 0 75
ASE_00186 0.66 0.51 0.86 67 78925 14 0 11 3 65
ASE_00187 0.69 0.51 0.92 59 68571 5 1 4 0 56
ASE_00189 0.76 0.62 0.94 63 63123 8 0 4 4 39
ASE_00190 0.74 0.54 1.00 49 45402 3 0 0 3 41
ASE_00192 0.51 0.35 0.75 47 84603 20 0 16 4 86
ASE_00194 0.72 0.53 0.97 63 73471 7 0 2 5 56
ASE_00196 0.82 0.69 0.96 52 31572 2 0 2 0 23
ASE_00197 0.63 0.46 0.86 67 89175 12 0 11 1 78
ASE_00203 0.72 0.55 0.93 53 46608 4 2 2 0 43
ASE_00204 0.73 0.55 0.97 62 67832 7 1 1 5 50
ASE_00205 0.82 0.67 1.00 60 45996 1 0 0 1 30
ASE_00209 0.83 0.69 0.98 61 43009 1 0 1 0 27
ASE_00210 0.74 0.65 0.86 42 27212 9 0 7 2 23
ASE_00212 0.63 0.45 0.89 66 93887 9 0 8 1 82
ASE_00213 0.83 0.71 0.98 47 27213 3 0 1 2 19
ASE_00214 0.73 0.54 0.98 56 56223 2 1 0 1 47
ASE_00215 0.51 0.32 0.82 32 48477 7 0 7 0 67
ASE_00216 0.81 0.66 1.00 54 39286 0 0 0 0 28
ASE_00217 0.82 0.67 1.00 60 40410 1 0 0 1 30
ASE_00221 0.83 0.70 0.99 82 64537 1 0 1 0 35
ASE_00222 0.65 0.42 1.00 66 112035 0 0 0 0 91
ASE_00227 0.57 0.43 0.76 57 78928 18 0 18 0 76
ASE_00228 0.72 0.57 0.91 49 46917 6 3 2 1 37
ASE_00229 0.78 0.61 1.00 53 42433 2 0 0 2 34
ASE_00231 0.59 0.45 0.78 43 47840 12 0 12 0 53
ASE_00232 0.81 0.65 1.00 55 38448 0 0 0 0 29
ASE_00234 0.64 0.43 0.95 55 75408 3 3 0 0 74
ASE_00237 0.83 0.73 0.93 41 45709 3 1 2 0 15
ASE_00238 0.61 0.44 0.86 50 64203 8 2 6 0 64
ASE_00240 0.62 0.48 0.79 45 46608 12 0 12 0 48
ASE_00241 0.79 0.64 0.98 56 43899 1 0 1 0 31
ASE_00242 0.85 0.72 1.00 81 60994 1 0 0 1 31
ASE_00246 0.79 0.67 0.92 45 48156 4 1 3 0 22
ASE_00247 0.79 0.69 0.90 44 54236 5 1 4 0 20
ASE_00248 0.84 0.71 1.00 81 62400 1 0 0 1 33
ASE_00250 0.72 0.56 0.91 74 78922 8 1 6 1 57
ASE_00252 0.63 0.43 0.92 72 115362 10 2 4 4 96
ASE_00254 0.81 0.66 1.00 54 36802 0 0 0 0 28
ASE_00255 0.64 0.51 0.80 66 74609 16 0 16 0 64
ASE_00257 0.68 0.52 0.91 50 50985 5 1 4 0 47
ASE_00263 0.68 0.47 0.98 56 70443 1 1 0 0 64
ASE_00264 0.58 0.40 0.85 40 49094 8 0 7 1 60
ASE_00267 0.80 0.64 1.00 56 45094 0 0 0 0 32
ASE_00270 0.55 0.34 0.90 43 72342 6 0 5 1 85
ASE_00274 0.71 0.53 0.95 55 55553 3 3 0 0 48
ASE_00277 0.73 0.57 0.93 52 48149 4 3 1 0 39
ASE_00279 0.73 0.54 0.98 55 53245 1 0 1 0 46
ASE_00280 0.74 0.57 0.97 56 51945 2 1 1 0 42
ASE_00281 0.78 0.63 0.98 55 44495 1 0 1 0 33
ASE_00282 0.66 0.45 0.98 57 77757 1 1 0 0 70
ASE_00283 0.72 0.52 0.98 56 61719 1 0 1 0 51
ASE_00284 0.72 0.53 0.98 57 58253 1 1 0 0 51
ASE_00285 0.68 0.47 1.00 57 68949 0 0 0 0 65
ASE_00286 0.78 0.61 1.00 56 46609 0 0 0 0 36
ASE_00287 0.67 0.50 0.89 51 54889 6 0 6 0 52
ASE_00288 0.75 0.58 0.96 54 46000 2 2 0 0 39
ASE_00289 0.66 0.46 0.95 73 100948 4 0 4 0 84
ASE_00292 0.76 0.58 1.00 80 81730 1 0 0 1 58
ASE_00294 0.68 0.47 0.98 81 114398 2 0 2 0 90
ASE_00295 0.77 0.59 1.00 77 73843 0 0 0 0 54
ASE_00296 0.73 0.54 0.98 79 91725 3 0 2 1 66
ASE_00297 0.61 0.45 0.83 44 52922 9 2 7 0 54
ASE_00298 0.70 0.50 0.98 56 67471 1 1 0 0 57
ASE_00299 0.55 0.44 0.70 44 49392 19 0 19 0 56
ASE_00313 0.50 0.34 0.75 30 62441 14 2 8 4 59
ASE_00316 0.46 0.27 0.79 26 107847 8 0 7 1 72
ASE_00318 0.79 0.62 1.00 73 80127 6 0 0 6 45
ASE_00327 0.61 0.43 0.86 38 57247 11 0 6 5 51
ASE_00328 0.83 0.70 1.00 78 72693 5 0 0 5 34
ASE_00330 0.66 0.48 0.91 43 56233 5 0 4 1 47
ASE_00332 0.78 0.60 1.00 83 81727 0 0 0 0 55
ASE_00335 0.81 0.66 1.00 77 75389 7 0 0 7 39
ASE_00337 0.57 0.44 0.76 31 39299 18 0 10 8 40
ASE_00338 0.51 0.33 0.80 32 66390 8 0 8 0 66
ASE_00339 0.58 0.46 0.72 55 80124 22 7 14 1 64
ASE_00340 0.73 0.56 0.94 48 46005 7 0 3 4 37
ASE_00342 0.84 0.71 1.00 82 62399 0 0 0 0 33
ASE_00343 0.37 0.27 0.51 31 83375 32 2 28 2 82
ASE_00346 0.61 0.49 0.75 48 48141 16 0 16 0 49
ASE_00353 0.72 0.52 0.98 56 57913 2 1 0 1 51
ASE_00359 0.77 0.61 0.98 49 42728 2 0 1 1 31
ASE_00360 0.87 0.77 0.98 50 29352 1 0 1 0 15
ASE_00361 0.65 0.43 0.98 55 75410 1 1 0 0 72
ASE_00362 0.78 0.62 1.00 56 48149 1 0 0 1 35
ASE_00363 0.70 0.54 0.89 51 51303 6 0 6 0 43
ASE_00364 0.66 0.49 0.89 51 54228 6 1 5 0 54
ASE_00366 0.69 0.53 0.90 52 58595 6 2 4 0 46
ASE_00367 0.81 0.65 1.00 56 43015 1 0 0 1 30
ASE_00369 0.73 0.53 1.00 57 55888 0 0 0 0 50
ASE_00370 0.78 0.62 0.98 52 41852 1 0 1 0 32
ASE_00372 0.73 0.54 0.98 54 51948 1 0 1 0 46
ASE_00374 0.78 0.60 1.00 53 44797 0 0 0 0 35
ASE_00375 0.71 0.51 1.00 56 60322 1 0 0 1 54
ASE_00376 0.68 0.50 0.93 53 56896 4 0 4 0 52
ASE_00377 0.67 0.50 0.91 53 57572 5 1 4 0 54
ASE_00379 0.79 0.63 1.00 56 46000 1 0 0 1 33
ASE_00380 0.75 0.57 1.00 56 54890 0 0 0 0 43
ASE_00382 0.80 0.64 1.00 54 41851 1 0 0 1 30
ASE_00383 0.74 0.54 1.00 57 54558 0 0 0 0 48
ASE_00384 0.78 0.61 1.00 56 48460 0 0 0 0 36
ASE_00385 0.71 0.56 0.90 45 41855 5 0 5 0 36
ASE_00386 0.77 0.59 1.00 57 50346 0 0 0 0 39
ASE_00387 0.63 0.46 0.87 48 55890 7 0 7 0 56
ASE_00388 0.77 0.60 1.00 53 45700 1 0 0 1 36
ASE_00390 0.78 0.62 0.98 53 42141 1 0 1 0 32
ASE_00393 0.71 0.56 0.91 52 47838 5 0 5 0 41
ASE_00394 0.76 0.58 1.00 54 46917 0 0 0 0 39
ASE_00395 0.80 0.64 1.00 54 41562 0 0 0 0 30
ASE_00396 0.81 0.65 1.00 54 41562 0 0 0 0 29
ASE_00397 0.74 0.54 1.00 57 54558 0 0 0 0 48
ASE_00398 0.72 0.52 1.00 54 55891 0 0 0 0 50
ASE_00400 0.72 0.52 1.00 55 57915 1 0 0 1 51
ASE_00401 0.62 0.40 0.96 50 76976 2 1 1 0 76
ASE_00402 0.80 0.65 1.00 55 42431 0 0 0 0 30
ASE_00403 0.73 0.53 1.00 57 55888 0 0 0 0 50
ASE_00404 0.80 0.65 1.00 55 43016 1 0 0 1 30
ASE_00406 0.78 0.61 1.00 57 48771 0 0 0 0 37
ASE_00411 0.67 0.55 0.82 49 49395 11 5 6 0 40
ASE_00412 0.63 0.47 0.84 49 58253 9 2 7 0 56
ASE_00413 0.72 0.57 0.90 46 44500 7 2 3 2 35
ASE_00414 0.58 0.44 0.76 42 46305 13 3 10 0 53
ASE_00415 0.57 0.40 0.80 41 54895 10 0 10 0 62
ASE_00416 0.76 0.61 0.94 78 77338 5 1 4 0 49
ASE_00417 0.80 0.65 0.98 65 54549 1 0 1 0 35
ASE_00418 0.81 0.67 0.98 50 38730 1 0 1 0 25
ASE_00419 0.67 0.50 0.89 51 54889 6 2 4 0 52
ASE_00422 0.74 0.57 0.96 54 46915 3 0 2 1 40
ASE_00423 0.77 0.64 0.93 70 56878 6 0 5 1 39
ASE_00426 0.52 0.41 0.68 44 61010 22 5 16 1 64
ASE_00428 0.77 0.62 0.94 78 76553 5 1 4 0 47
ASE_00430 0.73 0.55 0.98 53 46917 1 0 1 0 44
ASE_00431 0.56 0.44 0.71 42 46301 17 7 10 0 53
ASE_00434 0.74 0.61 0.89 67 68190 14 0 8 6 43
ASE_00437 0.52 0.40 0.67 54 79320 27 0 27 0 81
ASE_00438 0.62 0.42 0.92 49 66013 4 1 3 0 67
ASE_00441 0.65 0.44 0.96 49 64210 3 0 2 1 63
ASE_00447 0.84 0.71 1.00 82 60296 0 0 0 0 34
ASE_00448 0.81 0.69 0.95 77 64180 4 0 4 0 35
ASE_00451 0.79 0.64 0.96 80 70793 3 0 3 0 45
CRW_00013 0.37 0.21 0.65 24 103703 17 1 12 4 91
CRW_00016 0.36 0.20 0.65 24 77384 16 1 12 3 96
CRW_00610 0.51 0.33 0.77 27 36280 11 1 7 3 54
CRW_00613 0.48 0.32 0.71 25 34945 14 0 10 4 53
CRW_00614 0.43 0.30 0.63 17 121744 16 2 8 6 40
CRW_00618 0.41 0.28 0.61 17 56252 12 3 8 1 44
CRW_00633 0.31 0.17 0.58 18 63515 14 2 11 1 88
CRW_00634 0.35 0.20 0.61 19 64589 20 1 11 8 75
CRW_00670 0.49 0.28 0.89 33 70088 8 0 4 4 87
CRW_00671 0.50 0.28 0.89 33 62798 8 0 4 4 84
CRW_00672 0.51 0.30 0.89 33 72353 8 0 4 4 78
CRW_00674 0.29 0.16 0.54 20 83399 20 6 11 3 104
CRW_00676 0.35 0.17 0.69 20 93499 20 0 9 11 95
CRW_00692 0.39 0.22 0.69 20 68606 20 0 9 11 70
PDB_00827 0.58 0.40 0.84 32 26990 6 1 5 0 49
PDB_00919 0.49 0.35 0.69 36 44201 18 0 16 2 67
RFA_00597 0.73 0.64 0.83 70 97819 19 0 14 5 39
RFA_00598 0.72 0.63 0.81 64 84587 26 0 15 11 37
RFA_00599 0.85 0.73 0.99 81 101393 4 0 1 3 30
RFA_00600 0.79 0.68 0.92 68 120221 15 0 6 9 32
RFA_00601 0.82 0.71 0.95 81 99150 9 0 4 5 33
RFA_00602 0.81 0.71 0.93 82 101387 10 0 6 4 34
TMR_00173 0.12 0.07 0.19 3 42179 23 0 13 10 39
TMR_00357 0.37 0.26 0.52 24 82982 24 7 15 2 68
TMR_00601 0.51 0.38 0.70 16 58973 33 2 5 26 26
TMR_00696 0.44 0.30 0.65 34 85026 19 2 16 1 80

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Performance of CentroidHomfold‑LAST - scored lower in this pairwise comparison

1. Total counts & total scores for CentroidHomfold‑LAST

Total Base Pair Counts
Total TP 14505
Total TN 16868669
Total FP 2088
Total FP CONTRA 221
Total FP INCONS 1414
Total FP COMP 453
Total FN 14082
Total Scores
MCC 0.675
Average MCC ± 95% Confidence Intervals 0.670 ± 0.014
Sensitivity 0.507
Positive Predictive Value 0.899
Nr of predictions 273

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2. Individual counts for CentroidHomfold‑LAST [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00001 0.77 0.60 0.98 45 34145 5 0 1 4 30
ASE_00002 0.82 0.77 0.88 56 35447 11 1 7 3 17
ASE_00004 0.66 0.46 0.94 45 47847 3 1 2 0 52
ASE_00005 0.81 0.67 0.98 78 57890 3 0 2 1 39
ASE_00006 0.67 0.52 0.87 48 47531 7 1 6 0 45
ASE_00007 0.79 0.65 0.95 72 59609 9 0 4 5 38
ASE_00009 0.56 0.34 0.92 23 26081 3 0 2 1 44
ASE_00012 0.76 0.62 0.94 76 73839 7 2 3 2 47
ASE_00014 0.55 0.35 0.86 37 54242 6 1 5 0 69
ASE_00017 0.56 0.38 0.83 24 51011 5 0 5 0 40
ASE_00018 0.82 0.70 0.95 94 80502 7 0 5 2 40
ASE_00020 0.66 0.48 0.91 60 73854 7 1 5 1 66
ASE_00021 0.67 0.47 0.96 75 104118 5 0 3 2 85
ASE_00022 0.67 0.52 0.87 65 82953 13 0 10 3 59
ASE_00023 0.63 0.41 0.96 52 84201 4 0 2 2 75
ASE_00025 0.54 0.35 0.83 25 78576 5 0 5 0 46
ASE_00026 0.67 0.50 0.89 55 59623 8 0 7 1 55
ASE_00028 0.70 0.53 0.92 67 84593 8 0 6 2 59
ASE_00029 0.65 0.49 0.86 60 82958 11 0 10 1 62
ASE_00030 0.53 0.30 0.93 43 85445 3 1 2 0 102
ASE_00031 0.76 0.59 0.97 74 86660 4 0 2 2 52
ASE_00032 0.70 0.57 0.87 67 80123 12 0 10 2 51
ASE_00033 0.78 0.63 0.96 76 64901 4 0 3 1 45
ASE_00035 0.65 0.44 0.95 52 70445 8 1 2 5 66
ASE_00036 0.67 0.52 0.87 68 75777 13 3 7 3 64
ASE_00037 0.78 0.65 0.94 72 59263 8 0 5 3 38
ASE_00038 0.79 0.66 0.94 67 53557 5 1 3 1 34
ASE_00040 0.64 0.44 0.94 59 78940 5 2 2 1 74
ASE_00041 0.73 0.56 0.95 61 57566 7 0 3 4 47
ASE_00042 0.74 0.58 0.93 84 90010 6 1 5 0 61
ASE_00044 0.82 0.70 0.97 73 54540 3 0 2 1 32
ASE_00046 0.73 0.56 0.95 58 50342 3 0 3 0 45
ASE_00047 0.71 0.50 1.00 65 74240 0 0 0 0 65
ASE_00052 0.53 0.33 0.84 37 61381 7 0 7 0 75
ASE_00053 0.61 0.44 0.85 58 79333 12 3 7 2 75
ASE_00057 0.66 0.51 0.87 68 82137 13 5 5 3 66
ASE_00064 0.75 0.61 0.93 54 45393 8 0 4 4 35
ASE_00066 0.73 0.53 1.00 69 72321 0 0 0 0 61
ASE_00068 0.70 0.49 1.00 42 37633 0 0 0 0 43
ASE_00069 0.70 0.56 0.88 79 82938 14 5 6 3 61
ASE_00074 0.76 0.62 0.94 74 67817 7 1 4 2 45
ASE_00075 0.62 0.42 0.93 68 108738 7 1 4 2 94
ASE_00076 0.60 0.38 0.96 45 68218 2 0 2 0 73
ASE_00077 0.77 0.65 0.90 56 45088 7 2 4 1 30
ASE_00078 0.82 0.72 0.94 60 43007 5 1 3 1 23
ASE_00079 0.63 0.42 0.93 42 55566 4 0 3 1 58
ASE_00080 0.48 0.30 0.77 37 71583 11 0 11 0 86
ASE_00081 0.71 0.55 0.93 53 49713 5 1 3 1 44
ASE_00082 0.44 0.22 0.89 25 70472 3 0 3 0 91
ASE_00083 0.72 0.56 0.93 62 62414 6 1 4 1 48
ASE_00084 0.73 0.62 0.87 61 53558 11 2 7 2 38
ASE_00087 0.58 0.44 0.77 63 88328 21 2 17 2 81
ASE_00090 0.69 0.60 0.78 61 55533 17 1 16 0 40
ASE_00092 0.68 0.49 0.96 55 63489 4 0 2 2 58
ASE_00096 0.51 0.30 0.89 34 63508 5 0 4 1 81
ASE_00099 0.82 0.68 0.98 82 64536 3 1 1 1 38
ASE_00100 0.54 0.34 0.84 26 82184 6 0 5 1 50
ASE_00102 0.50 0.27 0.94 45 117807 3 1 2 0 121
ASE_00104 0.80 0.69 0.93 82 64173 7 1 5 1 37
ASE_00105 0.61 0.43 0.87 48 64206 9 0 7 2 63
ASE_00107 0.78 0.72 0.84 91 73045 19 1 16 2 36
ASE_00108 0.59 0.41 0.84 26 46940 5 0 5 0 37
ASE_00111 0.60 0.44 0.83 25 50056 5 0 5 0 32
ASE_00112 0.79 0.64 0.99 74 75391 4 0 1 3 42
ASE_00115 0.68 0.50 0.93 51 54560 7 0 4 3 50
ASE_00116 0.48 0.23 1.00 15 31611 2 0 0 2 51
ASE_00118 0.52 0.27 1.00 28 60698 2 0 0 2 74
ASE_00119 0.34 0.13 0.88 14 62819 2 0 2 0 94
ASE_00120 0.67 0.53 0.85 50 46912 9 1 8 0 44
ASE_00121 0.57 0.39 0.82 36 45106 8 1 7 0 56
ASE_00122 0.78 0.61 1.00 54 43311 0 0 0 0 34
ASE_00123 0.64 0.46 0.89 39 38459 6 1 4 1 46
ASE_00125 0.68 0.50 0.92 44 39292 5 1 3 1 44
ASE_00128 0.72 0.56 0.93 56 53241 4 1 3 0 44
ASE_00129 0.74 0.64 0.87 71 62753 13 1 10 2 40
ASE_00131 0.63 0.45 0.88 38 39297 9 1 4 4 47
ASE_00132 0.65 0.47 0.88 45 50352 7 2 4 1 50
ASE_00134 0.74 0.61 0.91 58 50339 7 1 5 1 37
ASE_00135 0.64 0.46 0.89 50 63134 7 1 5 1 59
ASE_00136 0.75 0.61 0.92 56 48144 8 1 4 3 36
ASE_00137 0.80 0.68 0.93 67 48444 5 1 4 0 31
ASE_00138 0.80 0.65 0.98 53 40416 2 0 1 1 28
ASE_00139 0.65 0.42 1.00 44 54241 0 0 0 0 60
ASE_00140 0.66 0.47 0.92 59 70812 7 1 4 2 66
ASE_00142 0.80 0.70 0.92 85 67069 8 3 4 1 37
ASE_00145 0.64 0.50 0.81 56 70056 13 0 13 0 55
ASE_00146 0.68 0.54 0.86 67 70798 12 1 10 1 57
ASE_00148 0.49 0.27 0.89 41 112529 5 0 5 0 113
ASE_00151 0.73 0.62 0.86 61 51932 10 4 6 0 37
ASE_00153 0.54 0.48 0.60 35 57572 43 2 21 20 38
ASE_00154 0.60 0.43 0.85 46 65287 8 0 8 0 61
ASE_00155 0.56 0.35 0.88 50 93471 7 0 7 0 92
ASE_00163 0.72 0.54 0.96 50 53249 2 0 2 0 43
ASE_00165 0.67 0.50 0.89 51 52918 6 1 5 0 50
ASE_00168 0.44 0.25 0.76 16 60705 5 0 5 0 48
ASE_00169 0.62 0.39 0.98 42 57248 1 0 1 0 65
ASE_00170 0.70 0.55 0.89 51 48771 6 0 6 0 42
ASE_00171 0.72 0.57 0.92 54 48457 7 1 4 2 40
ASE_00172 0.69 0.49 0.98 52 58943 2 0 1 1 54
ASE_00174 0.66 0.47 0.94 51 61021 3 1 2 0 58
ASE_00175 0.53 0.42 0.66 45 59963 24 3 20 1 62
ASE_00176 0.62 0.39 1.00 43 59988 0 0 0 0 67
ASE_00179 0.71 0.52 0.96 44 44207 2 1 1 0 40
ASE_00180 0.70 0.53 0.91 53 51302 6 0 5 1 47
ASE_00181 0.71 0.54 0.95 57 57570 5 0 3 2 49
ASE_00182 0.55 0.35 0.86 48 84199 8 1 7 0 88
ASE_00184 0.69 0.58 0.83 59 54544 13 2 10 1 43
ASE_00185 0.62 0.41 0.95 52 73481 4 1 2 1 76
ASE_00186 0.79 0.73 0.86 96 78892 16 1 14 1 36
ASE_00187 0.65 0.44 0.94 51 68581 5 0 3 2 64
ASE_00189 0.42 0.23 0.77 23 63160 7 0 7 0 79
ASE_00190 0.46 0.23 0.91 21 45428 3 0 2 1 69
ASE_00192 0.30 0.09 1.00 12 84654 0 0 0 0 121
ASE_00194 0.43 0.18 1.00 22 73514 0 0 0 0 97
ASE_00196 0.65 0.47 0.90 35 31587 4 0 4 0 40
ASE_00197 0.74 0.64 0.86 93 89145 15 1 14 0 52
ASE_00203 0.82 0.70 0.96 67 46595 4 1 2 1 29
ASE_00204 0.33 0.13 0.83 15 67878 3 0 3 0 97
ASE_00205 0.68 0.54 0.84 49 45998 12 0 9 3 41
ASE_00209 0.63 0.45 0.87 40 43025 6 1 5 0 48
ASE_00210 0.79 0.69 0.90 45 27211 5 0 5 0 20
ASE_00212 0.75 0.65 0.86 96 93849 16 1 15 0 52
ASE_00213 0.85 0.77 0.94 51 27207 5 0 3 2 15
ASE_00214 0.69 0.59 0.80 61 56204 17 2 13 2 42
ASE_00215 0.62 0.40 0.95 40 48474 3 1 1 1 59
ASE_00216 0.82 0.71 0.95 58 39279 3 0 3 0 24
ASE_00217 0.67 0.56 0.82 50 40409 14 1 10 3 40
ASE_00221 0.75 0.61 0.93 71 64544 6 1 4 1 46
ASE_00222 0.52 0.31 0.86 49 112044 8 0 8 0 108
ASE_00227 0.41 0.18 0.92 24 78977 2 0 2 0 109
ASE_00228 0.79 0.69 0.92 59 46907 6 2 3 1 27
ASE_00229 0.79 0.69 0.90 60 42419 7 1 6 0 27
ASE_00231 0.76 0.63 0.92 60 47830 5 1 4 0 36
ASE_00232 0.85 0.75 0.95 63 38437 3 2 1 0 21
ASE_00234 0.61 0.42 0.90 54 75406 8 1 5 2 75
ASE_00237 0.67 0.54 0.83 30 45717 6 0 6 0 26
ASE_00238 0.57 0.37 0.89 42 64214 5 0 5 0 72
ASE_00240 0.53 0.30 0.93 28 46635 2 1 1 0 65
ASE_00241 0.73 0.64 0.84 56 43889 12 2 9 1 31
ASE_00242 0.81 0.71 0.93 79 60990 7 0 6 1 33
ASE_00246 0.37 0.22 0.63 15 48181 9 1 8 0 52
ASE_00247 0.67 0.52 0.87 33 54247 5 0 5 0 31
ASE_00248 0.82 0.71 0.94 81 62395 6 0 5 1 33
ASE_00250 0.70 0.50 1.00 65 78938 0 0 0 0 66
ASE_00252 0.58 0.37 0.93 62 115373 6 0 5 1 106
ASE_00254 0.84 0.74 0.95 61 36792 4 2 1 1 21
ASE_00255 0.73 0.57 0.94 74 74612 5 0 5 0 56
ASE_00257 0.82 0.68 0.99 66 50973 2 0 1 1 31
ASE_00263 0.69 0.48 0.98 58 70441 2 0 1 1 62
ASE_00264 0.77 0.61 0.98 61 49079 7 0 1 6 39
ASE_00267 0.72 0.66 0.79 58 45077 17 2 13 2 30
ASE_00270 0.52 0.27 1.00 35 72355 0 0 0 0 93
ASE_00274 0.66 0.47 0.92 48 55559 5 0 4 1 55
ASE_00277 0.64 0.56 0.74 51 48136 21 3 15 3 40
ASE_00279 0.72 0.58 0.89 59 53235 8 3 4 1 42
ASE_00280 0.75 0.58 0.97 57 51944 3 0 2 1 41
ASE_00281 0.81 0.68 0.97 60 44489 2 1 1 0 28
ASE_00282 0.60 0.40 0.89 51 77758 7 3 3 1 76
ASE_00283 0.71 0.56 0.91 60 61710 7 2 4 1 47
ASE_00284 0.68 0.51 0.90 55 58250 7 2 4 1 53
ASE_00285 0.63 0.44 0.89 54 68945 8 3 4 1 68
ASE_00286 0.75 0.59 0.95 54 46608 3 1 2 0 38
ASE_00287 0.66 0.49 0.91 50 54891 6 0 5 1 53
ASE_00288 0.70 0.51 0.96 47 46007 2 0 2 0 46
ASE_00289 0.53 0.30 0.94 47 100975 3 0 3 0 110
ASE_00292 0.55 0.43 0.71 59 81727 25 3 21 1 79
ASE_00294 0.75 0.60 0.94 103 114372 8 1 5 2 68
ASE_00295 0.70 0.54 0.91 71 73842 8 1 6 1 60
ASE_00296 0.71 0.53 0.96 77 91726 4 0 3 1 68
ASE_00297 0.68 0.47 0.98 46 52928 1 0 1 0 52
ASE_00298 0.62 0.39 1.00 44 67484 1 0 0 1 69
ASE_00299 0.74 0.58 0.94 58 49393 8 1 3 4 42
ASE_00313 0.62 0.52 0.74 46 62419 16 2 14 0 43
ASE_00316 0.57 0.41 0.78 40 107829 16 2 9 5 58
ASE_00318 0.55 0.35 0.87 41 80153 12 0 6 6 77
ASE_00327 0.78 0.70 0.87 62 57220 13 3 6 4 27
ASE_00328 0.80 0.66 0.97 74 72695 9 0 2 7 38
ASE_00330 0.66 0.46 0.95 41 56237 6 0 2 4 49
ASE_00332 0.80 0.71 0.89 98 81700 14 1 11 2 40
ASE_00335 0.80 0.66 0.97 76 75388 8 0 2 6 40
ASE_00337 0.53 0.51 0.55 36 39275 45 5 24 16 35
ASE_00338 0.67 0.61 0.73 60 66348 36 3 19 14 38
ASE_00339 0.79 0.64 0.97 76 80122 8 0 2 6 43
ASE_00340 0.63 0.48 0.84 41 46007 11 6 2 3 44
ASE_00342 0.82 0.75 0.90 86 62385 12 1 9 2 29
ASE_00343 0.73 0.61 0.88 69 83358 16 0 9 7 44
ASE_00346 0.52 0.41 0.67 40 48145 24 3 17 4 57
ASE_00353 0.79 0.69 0.91 74 57889 7 1 6 0 33
ASE_00359 0.44 0.23 0.86 18 42757 3 0 3 0 62
ASE_00360 0.64 0.52 0.79 34 29360 9 1 8 0 31
ASE_00361 0.65 0.43 0.96 55 75409 4 0 2 2 72
ASE_00362 0.80 0.69 0.93 63 48137 7 1 4 2 28
ASE_00363 0.75 0.64 0.88 60 51292 9 1 7 1 34
ASE_00364 0.79 0.67 0.93 70 54210 6 1 4 1 35
ASE_00366 0.68 0.49 0.94 48 58602 4 0 3 1 50
ASE_00367 0.78 0.70 0.87 60 43002 11 1 8 2 26
ASE_00369 0.79 0.64 0.97 68 55875 2 0 2 0 39
ASE_00370 0.78 0.67 0.90 56 41843 7 1 5 1 28
ASE_00372 0.70 0.54 0.90 54 51943 6 3 3 0 46
ASE_00374 0.77 0.64 0.93 56 44790 4 2 2 0 32
ASE_00375 0.71 0.50 1.00 55 60323 0 0 0 0 55
ASE_00376 0.65 0.51 0.83 54 56888 15 0 11 4 51
ASE_00377 0.75 0.62 0.92 66 57558 7 0 6 1 41
ASE_00379 0.75 0.63 0.90 56 45994 6 2 4 0 33
ASE_00380 0.69 0.47 1.00 47 54899 0 0 0 0 52
ASE_00382 0.78 0.69 0.89 58 41840 8 1 6 1 26
ASE_00383 0.79 0.66 0.95 69 54542 5 1 3 1 36
ASE_00384 0.78 0.68 0.90 63 48446 8 1 6 1 29
ASE_00385 0.68 0.53 0.88 43 41856 6 3 3 0 38
ASE_00386 0.70 0.56 0.87 54 50341 9 1 7 1 42
ASE_00387 0.63 0.45 0.87 47 55891 8 1 6 1 57
ASE_00388 0.78 0.69 0.90 61 45685 9 1 6 2 28
ASE_00390 0.81 0.72 0.91 61 42128 8 1 5 2 24
ASE_00393 0.70 0.57 0.87 53 47834 9 1 7 1 40
ASE_00394 0.72 0.62 0.83 58 46901 14 1 11 2 35
ASE_00395 0.78 0.71 0.86 60 41546 12 1 9 2 24
ASE_00396 0.78 0.71 0.86 59 41547 12 2 8 2 24
ASE_00397 0.80 0.69 0.92 72 54537 7 1 5 1 33
ASE_00398 0.68 0.53 0.87 55 55882 11 1 7 3 49
ASE_00400 0.67 0.45 0.98 48 57921 1 0 1 0 58
ASE_00401 0.60 0.37 0.98 47 76980 2 0 1 1 79
ASE_00402 0.79 0.68 0.91 58 42422 8 1 5 2 27
ASE_00403 0.75 0.63 0.91 67 55871 7 1 6 0 40
ASE_00404 0.81 0.69 0.94 59 43008 5 0 4 1 26
ASE_00406 0.73 0.62 0.85 58 48760 12 1 9 2 36
ASE_00411 0.64 0.44 0.93 39 49413 3 0 3 0 50
ASE_00412 0.62 0.40 0.98 42 58268 3 0 1 2 63
ASE_00413 0.72 0.54 0.96 44 44505 2 0 2 0 37
ASE_00414 0.62 0.47 0.80 45 46304 11 0 11 0 50
ASE_00415 0.55 0.34 0.90 35 54907 4 0 4 0 68
ASE_00416 0.58 0.36 0.92 46 77371 5 1 3 1 81
ASE_00417 0.51 0.43 0.61 43 54545 28 1 26 1 57
ASE_00418 0.42 0.33 0.53 25 38734 23 1 21 1 50
ASE_00419 0.67 0.48 0.94 49 54894 3 1 2 0 54
ASE_00422 0.72 0.55 0.95 52 46916 4 0 3 1 42
ASE_00423 0.76 0.59 0.98 64 56888 2 1 0 1 45
ASE_00426 0.52 0.27 1.00 29 61046 0 0 0 0 79
ASE_00428 0.60 0.39 0.91 49 76582 6 1 4 1 76
ASE_00430 0.77 0.61 0.98 59 46911 3 0 1 2 38
ASE_00431 0.62 0.49 0.78 47 46300 13 1 12 0 48
ASE_00434 0.50 0.26 0.94 29 68234 2 0 2 0 81
ASE_00437 0.55 0.47 0.66 63 79305 35 1 32 2 72
ASE_00438 0.43 0.18 1.00 21 66045 0 0 0 0 95
ASE_00441 0.63 0.44 0.91 49 64207 9 0 5 4 63
ASE_00447 0.73 0.55 0.97 64 60312 3 0 2 1 52
ASE_00448 0.75 0.63 0.88 71 64180 11 1 9 1 41
ASE_00451 0.77 0.72 0.83 90 70768 20 1 17 2 35
CRW_00013 0.62 0.42 0.92 48 103688 4 0 4 0 67
CRW_00016 0.70 0.50 0.97 60 77359 2 0 2 0 60
CRW_00610 0.66 0.46 0.95 37 36276 2 0 2 0 44
CRW_00613 0.74 0.55 1.00 43 34937 0 0 0 0 35
CRW_00614 0.21 0.18 0.25 10 121731 73 7 23 43 47
CRW_00618 0.38 0.25 0.58 15 56254 20 1 10 9 46
CRW_00633 0.64 0.42 0.98 45 63500 2 1 0 1 61
CRW_00634 0.69 0.54 0.88 51 64562 7 1 6 0 43
CRW_00670 0.69 0.50 0.95 60 70062 3 0 3 0 60
CRW_00671 0.66 0.48 0.92 56 62774 5 1 4 0 61
CRW_00672 0.69 0.50 0.96 55 72333 3 0 2 1 56
CRW_00674 0.76 0.57 1.00 71 83365 1 0 0 1 53
CRW_00676 0.73 0.55 0.98 63 93464 3 0 1 2 52
CRW_00692 0.82 0.70 0.95 63 68569 3 0 3 0 27
PDB_00827 0.73 0.54 0.98 44 26983 2 0 1 1 37
PDB_00919 0.62 0.40 0.95 41 44210 2 0 2 0 62
RFA_00597 0.50 0.25 1.00 27 97876 3 0 0 3 82
RFA_00598 0.58 0.34 1.00 34 84632 5 0 0 5 67
RFA_00599 0.65 0.46 0.91 51 101419 10 3 2 5 60
RFA_00600 0.51 0.29 0.91 29 120263 7 0 3 4 71
RFA_00601 0.86 0.82 0.91 93 99133 20 3 6 11 21
RFA_00602 0.85 0.80 0.90 93 101372 20 3 7 10 23
TMR_00173 0.58 0.33 1.00 14 42181 0 0 0 0 28
TMR_00357 0.44 0.23 0.84 21 83003 4 0 4 0 71
TMR_00601 0.80 0.69 0.94 29 58965 10 0 2 8 13
TMR_00696 0.46 0.28 0.76 32 85036 10 2 8 0 82

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.