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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

  4. Performance of IPknot - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(seed) & IPknot [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(seed) IPknot
MCC 0.691 > 0.640
Average MCC ± 95% Confidence Intervals 0.688 ± 0.015 > 0.632 ± 0.017
Sensitivity 0.521 < 0.568
Positive Predictive Value 0.919 > 0.722
Total TP 15031 < 16389
Total TN 17467425 > 17461094
Total FP 1662 < 7681
Total FP CONTRA 179 < 945
Total FP INCONS 1150 < 5357
Total FP COMP 333 < 1379
Total FN 13846 > 12488
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of CentroidAlifold(seed) and IPknot. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(seed) and IPknot).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for CentroidAlifold(seed) and IPknot).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(seed) and IPknot. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(seed) and IPknot).

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Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(seed)

Total Base Pair Counts
Total TP 15031
Total TN 17467425
Total FP 1662
Total FP CONTRA 179
Total FP INCONS 1150
Total FP COMP 333
Total FN 13846
Total Scores
MCC 0.691
Average MCC ± 95% Confidence Intervals 0.688 ± 0.015
Sensitivity 0.521
Positive Predictive Value 0.919
Nr of predictions 277

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2. Individual counts for CentroidAlifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00001 0.81 0.65 1.00 49 34142 0 0 0 0 26
ASE_00002 0.82 0.67 1.00 49 35462 0 0 0 0 24
ASE_00004 0.61 0.45 0.83 44 47842 9 0 9 0 53
ASE_00005 0.75 0.57 0.97 67 57901 2 0 2 0 50
ASE_00006 0.58 0.44 0.76 41 47532 13 0 13 0 52
ASE_00007 0.83 0.71 0.98 78 59605 2 0 2 0 32
ASE_00009 0.79 0.67 0.94 45 26058 3 0 3 0 22
ASE_00012 0.75 0.59 0.95 73 73843 7 1 3 3 50
ASE_00014 0.74 0.58 0.95 61 54221 3 0 3 0 45
ASE_00017 0.79 0.69 0.90 44 50991 5 1 4 0 20
ASE_00018 0.78 0.60 1.00 81 80520 0 0 0 0 53
ASE_00020 0.63 0.43 0.93 54 73862 4 3 1 0 72
ASE_00021 0.63 0.44 0.90 71 104117 11 2 6 3 89
ASE_00022 0.80 0.65 1.00 80 82948 5 0 0 5 44
ASE_00023 0.47 0.35 0.63 45 84184 28 8 18 2 82
ASE_00025 0.69 0.58 0.84 41 78557 8 1 7 0 30
ASE_00026 0.80 0.67 0.96 74 59608 4 0 3 1 36
ASE_00028 0.80 0.64 1.00 81 84585 3 0 0 3 45
ASE_00029 0.45 0.34 0.61 41 82961 30 4 22 4 81
ASE_00030 0.66 0.49 0.90 71 85412 8 0 8 0 74
ASE_00031 0.51 0.37 0.72 46 86672 18 0 18 0 80
ASE_00032 0.38 0.27 0.54 32 80141 30 1 26 3 86
ASE_00033 0.80 0.65 0.99 79 64900 3 1 0 2 42
ASE_00035 0.77 0.64 0.94 75 70420 8 0 5 3 43
ASE_00036 0.75 0.58 0.99 76 75778 1 1 0 0 56
ASE_00037 0.84 0.71 1.00 78 59262 1 0 0 1 32
ASE_00038 0.74 0.54 1.00 55 53573 0 0 0 0 46
ASE_00040 0.77 0.59 1.00 79 78924 2 0 0 2 54
ASE_00041 0.77 0.64 0.92 69 57555 6 0 6 0 39
ASE_00042 0.65 0.49 0.87 71 90018 11 0 11 0 74
ASE_00044 0.83 0.70 1.00 73 54542 0 0 0 0 32
ASE_00046 0.73 0.62 0.86 64 50329 10 0 10 0 39
ASE_00047 0.70 0.52 0.93 68 74232 5 0 5 0 62
ASE_00052 0.75 0.63 0.91 70 61348 8 0 7 1 42
ASE_00053 0.71 0.54 0.92 72 79323 6 3 3 0 61
ASE_00057 0.73 0.57 0.93 77 82132 6 2 4 0 57
ASE_00064 0.77 0.60 1.00 53 45398 0 0 0 0 36
ASE_00066 0.75 0.56 1.00 73 72317 1 0 0 1 57
ASE_00068 0.54 0.38 0.78 32 37634 9 0 9 0 53
ASE_00069 0.75 0.57 0.98 80 82946 3 0 2 1 60
ASE_00074 0.83 0.69 1.00 82 67814 1 0 0 1 37
ASE_00075 0.64 0.44 0.92 71 108734 11 1 5 5 91
ASE_00076 0.69 0.48 1.00 57 68208 0 0 0 0 61
ASE_00077 0.79 0.64 0.96 55 45093 2 1 1 0 31
ASE_00078 0.83 0.69 1.00 57 43014 0 0 0 0 26
ASE_00079 0.63 0.47 0.84 47 55555 9 0 9 0 53
ASE_00080 0.45 0.30 0.66 37 71575 19 1 18 0 86
ASE_00081 0.77 0.59 1.00 57 49713 0 0 0 0 40
ASE_00082 0.66 0.43 1.00 50 70450 6 0 0 6 66
ASE_00083 0.72 0.52 1.00 57 62424 0 0 0 0 53
ASE_00084 0.75 0.57 0.98 56 53571 1 1 0 0 43
ASE_00087 0.60 0.38 0.95 54 88353 3 0 3 0 90
ASE_00090 0.75 0.56 1.00 57 55554 0 0 0 0 44
ASE_00092 0.70 0.50 0.98 56 63489 1 1 0 0 57
ASE_00096 0.63 0.44 0.89 51 63489 6 0 6 0 64
ASE_00099 0.82 0.67 1.00 80 64540 0 0 0 0 40
ASE_00100 0.72 0.58 0.90 44 82166 5 1 4 0 32
ASE_00102 0.57 0.40 0.81 66 117774 15 1 14 0 100
ASE_00104 0.81 0.67 0.99 80 64180 1 0 1 0 39
ASE_00105 0.55 0.40 0.76 44 64203 14 4 10 0 67
ASE_00107 0.78 0.63 0.96 80 73070 3 0 3 0 47
ASE_00108 0.79 0.70 0.90 44 46922 5 1 4 0 19
ASE_00111 0.83 0.74 0.93 42 50041 3 1 2 0 15
ASE_00112 0.50 0.34 0.71 40 75410 16 0 16 0 76
ASE_00115 0.74 0.54 1.00 55 54560 0 0 0 0 46
ASE_00116 0.86 0.76 0.98 50 31575 1 0 1 0 16
ASE_00118 0.68 0.49 0.94 50 60673 4 1 2 1 52
ASE_00119 0.66 0.44 0.98 48 62786 1 1 0 0 60
ASE_00120 0.79 0.64 0.98 60 46910 2 0 1 1 34
ASE_00121 0.81 0.66 0.98 61 45088 1 0 1 0 31
ASE_00122 0.80 0.64 1.00 56 43309 1 0 0 1 32
ASE_00123 0.68 0.48 0.95 41 38460 2 0 2 0 44
ASE_00125 0.67 0.47 0.95 41 39297 2 0 2 0 47
ASE_00128 0.73 0.54 1.00 54 53247 0 0 0 0 46
ASE_00129 0.71 0.50 1.00 56 62779 0 0 0 0 55
ASE_00131 0.65 0.44 0.97 37 39302 1 1 0 0 48
ASE_00132 0.76 0.59 0.98 56 50346 1 1 0 0 39
ASE_00134 0.69 0.54 0.89 51 50346 6 0 6 0 44
ASE_00135 0.53 0.39 0.74 42 63133 15 0 15 0 67
ASE_00136 0.75 0.59 0.95 54 48148 3 0 3 0 38
ASE_00137 0.70 0.53 0.93 52 48460 4 0 4 0 46
ASE_00138 0.79 0.63 1.00 51 40419 0 0 0 0 30
ASE_00139 0.73 0.54 1.00 56 54229 0 0 0 0 48
ASE_00140 0.64 0.43 0.95 54 70819 3 3 0 0 71
ASE_00142 0.77 0.61 0.97 75 67084 4 0 2 2 47
ASE_00145 0.77 0.59 1.00 66 70059 0 0 0 0 45
ASE_00146 0.78 0.62 0.97 77 70797 2 0 2 0 47
ASE_00148 0.62 0.41 0.95 63 112509 3 0 3 0 91
ASE_00151 0.80 0.70 0.92 69 51928 6 5 1 0 29
ASE_00153 0.67 0.53 0.85 39 57584 7 1 6 0 34
ASE_00154 0.75 0.59 0.95 63 65275 3 0 3 0 44
ASE_00155 0.68 0.46 1.00 66 93462 0 0 0 0 76
ASE_00163 0.77 0.59 1.00 55 53246 0 0 0 0 38
ASE_00165 0.69 0.50 0.94 51 52921 4 1 2 1 50
ASE_00168 0.79 0.69 0.90 44 60677 5 1 4 0 20
ASE_00169 0.65 0.48 0.88 51 57233 7 1 6 0 56
ASE_00170 0.78 0.60 1.00 56 48772 0 0 0 0 37
ASE_00171 0.76 0.59 1.00 55 48461 1 0 0 1 39
ASE_00172 0.72 0.53 0.98 56 58939 1 1 0 0 50
ASE_00174 0.60 0.43 0.82 47 61018 10 1 9 0 62
ASE_00175 0.71 0.51 0.98 55 59975 1 1 0 0 52
ASE_00176 0.71 0.50 1.00 55 59976 0 0 0 0 55
ASE_00179 0.79 0.63 0.98 53 44199 2 0 1 1 31
ASE_00180 0.73 0.54 0.98 54 51305 1 1 0 0 46
ASE_00181 0.71 0.52 0.96 55 57573 3 2 0 1 51
ASE_00182 0.61 0.40 0.95 54 84198 3 0 3 0 82
ASE_00184 0.75 0.56 1.00 57 54558 0 0 0 0 45
ASE_00185 0.64 0.41 0.98 53 73482 1 1 0 0 75
ASE_00186 0.66 0.51 0.86 67 78925 14 0 11 3 65
ASE_00187 0.69 0.51 0.92 59 68571 5 1 4 0 56
ASE_00189 0.76 0.62 0.94 63 63123 8 0 4 4 39
ASE_00190 0.74 0.54 1.00 49 45402 3 0 0 3 41
ASE_00192 0.51 0.35 0.75 47 84603 20 0 16 4 86
ASE_00194 0.72 0.53 0.97 63 73471 7 0 2 5 56
ASE_00196 0.82 0.69 0.96 52 31572 2 0 2 0 23
ASE_00197 0.63 0.46 0.86 67 89175 12 0 11 1 78
ASE_00203 0.72 0.55 0.93 53 46608 4 2 2 0 43
ASE_00204 0.73 0.55 0.97 62 67832 7 1 1 5 50
ASE_00205 0.82 0.67 1.00 60 45996 1 0 0 1 30
ASE_00209 0.83 0.69 0.98 61 43009 1 0 1 0 27
ASE_00210 0.74 0.65 0.86 42 27212 9 0 7 2 23
ASE_00212 0.63 0.45 0.89 66 93887 9 0 8 1 82
ASE_00213 0.83 0.71 0.98 47 27213 3 0 1 2 19
ASE_00214 0.73 0.54 0.98 56 56223 2 1 0 1 47
ASE_00215 0.51 0.32 0.82 32 48477 7 0 7 0 67
ASE_00216 0.81 0.66 1.00 54 39286 0 0 0 0 28
ASE_00217 0.82 0.67 1.00 60 40410 1 0 0 1 30
ASE_00221 0.83 0.70 0.99 82 64537 1 0 1 0 35
ASE_00222 0.65 0.42 1.00 66 112035 0 0 0 0 91
ASE_00227 0.57 0.43 0.76 57 78928 18 0 18 0 76
ASE_00228 0.72 0.57 0.91 49 46917 6 3 2 1 37
ASE_00229 0.78 0.61 1.00 53 42433 2 0 0 2 34
ASE_00231 0.59 0.45 0.78 43 47840 12 0 12 0 53
ASE_00232 0.81 0.65 1.00 55 38448 0 0 0 0 29
ASE_00234 0.64 0.43 0.95 55 75408 3 3 0 0 74
ASE_00237 0.83 0.73 0.93 41 45709 3 1 2 0 15
ASE_00238 0.61 0.44 0.86 50 64203 8 2 6 0 64
ASE_00240 0.62 0.48 0.79 45 46608 12 0 12 0 48
ASE_00241 0.79 0.64 0.98 56 43899 1 0 1 0 31
ASE_00242 0.85 0.72 1.00 81 60994 1 0 0 1 31
ASE_00246 0.79 0.67 0.92 45 48156 4 1 3 0 22
ASE_00247 0.79 0.69 0.90 44 54236 5 1 4 0 20
ASE_00248 0.84 0.71 1.00 81 62400 1 0 0 1 33
ASE_00250 0.72 0.56 0.91 74 78922 8 1 6 1 57
ASE_00252 0.63 0.43 0.92 72 115362 10 2 4 4 96
ASE_00254 0.81 0.66 1.00 54 36802 0 0 0 0 28
ASE_00255 0.64 0.51 0.80 66 74609 16 0 16 0 64
ASE_00257 0.68 0.52 0.91 50 50985 5 1 4 0 47
ASE_00263 0.68 0.47 0.98 56 70443 1 1 0 0 64
ASE_00264 0.58 0.40 0.85 40 49094 8 0 7 1 60
ASE_00267 0.80 0.64 1.00 56 45094 0 0 0 0 32
ASE_00270 0.55 0.34 0.90 43 72342 6 0 5 1 85
ASE_00274 0.71 0.53 0.95 55 55553 3 3 0 0 48
ASE_00277 0.73 0.57 0.93 52 48149 4 3 1 0 39
ASE_00279 0.73 0.54 0.98 55 53245 1 0 1 0 46
ASE_00280 0.74 0.57 0.97 56 51945 2 1 1 0 42
ASE_00281 0.78 0.63 0.98 55 44495 1 0 1 0 33
ASE_00282 0.66 0.45 0.98 57 77757 1 1 0 0 70
ASE_00283 0.72 0.52 0.98 56 61719 1 0 1 0 51
ASE_00284 0.72 0.53 0.98 57 58253 1 1 0 0 51
ASE_00285 0.68 0.47 1.00 57 68949 0 0 0 0 65
ASE_00286 0.78 0.61 1.00 56 46609 0 0 0 0 36
ASE_00287 0.67 0.50 0.89 51 54889 6 0 6 0 52
ASE_00288 0.75 0.58 0.96 54 46000 2 2 0 0 39
ASE_00289 0.66 0.46 0.95 73 100948 4 0 4 0 84
ASE_00292 0.76 0.58 1.00 80 81730 1 0 0 1 58
ASE_00294 0.68 0.47 0.98 81 114398 2 0 2 0 90
ASE_00295 0.77 0.59 1.00 77 73843 0 0 0 0 54
ASE_00296 0.73 0.54 0.98 79 91725 3 0 2 1 66
ASE_00297 0.61 0.45 0.83 44 52922 9 2 7 0 54
ASE_00298 0.70 0.50 0.98 56 67471 1 1 0 0 57
ASE_00299 0.55 0.44 0.70 44 49392 19 0 19 0 56
ASE_00313 0.50 0.34 0.75 30 62441 14 2 8 4 59
ASE_00316 0.46 0.27 0.79 26 107847 8 0 7 1 72
ASE_00318 0.79 0.62 1.00 73 80127 6 0 0 6 45
ASE_00327 0.61 0.43 0.86 38 57247 11 0 6 5 51
ASE_00328 0.83 0.70 1.00 78 72693 5 0 0 5 34
ASE_00330 0.66 0.48 0.91 43 56233 5 0 4 1 47
ASE_00332 0.78 0.60 1.00 83 81727 0 0 0 0 55
ASE_00335 0.81 0.66 1.00 77 75389 7 0 0 7 39
ASE_00337 0.57 0.44 0.76 31 39299 18 0 10 8 40
ASE_00338 0.51 0.33 0.80 32 66390 8 0 8 0 66
ASE_00339 0.58 0.46 0.72 55 80124 22 7 14 1 64
ASE_00340 0.73 0.56 0.94 48 46005 7 0 3 4 37
ASE_00342 0.84 0.71 1.00 82 62399 0 0 0 0 33
ASE_00343 0.37 0.27 0.51 31 83375 32 2 28 2 82
ASE_00346 0.61 0.49 0.75 48 48141 16 0 16 0 49
ASE_00353 0.72 0.52 0.98 56 57913 2 1 0 1 51
ASE_00359 0.77 0.61 0.98 49 42728 2 0 1 1 31
ASE_00360 0.87 0.77 0.98 50 29352 1 0 1 0 15
ASE_00361 0.65 0.43 0.98 55 75410 1 1 0 0 72
ASE_00362 0.78 0.62 1.00 56 48149 1 0 0 1 35
ASE_00363 0.70 0.54 0.89 51 51303 6 0 6 0 43
ASE_00364 0.66 0.49 0.89 51 54228 6 1 5 0 54
ASE_00366 0.69 0.53 0.90 52 58595 6 2 4 0 46
ASE_00367 0.81 0.65 1.00 56 43015 1 0 0 1 30
ASE_00369 0.73 0.53 1.00 57 55888 0 0 0 0 50
ASE_00370 0.78 0.62 0.98 52 41852 1 0 1 0 32
ASE_00372 0.73 0.54 0.98 54 51948 1 0 1 0 46
ASE_00374 0.78 0.60 1.00 53 44797 0 0 0 0 35
ASE_00375 0.71 0.51 1.00 56 60322 1 0 0 1 54
ASE_00376 0.68 0.50 0.93 53 56896 4 0 4 0 52
ASE_00377 0.67 0.50 0.91 53 57572 5 1 4 0 54
ASE_00379 0.79 0.63 1.00 56 46000 1 0 0 1 33
ASE_00380 0.75 0.57 1.00 56 54890 0 0 0 0 43
ASE_00382 0.80 0.64 1.00 54 41851 1 0 0 1 30
ASE_00383 0.74 0.54 1.00 57 54558 0 0 0 0 48
ASE_00384 0.78 0.61 1.00 56 48460 0 0 0 0 36
ASE_00385 0.71 0.56 0.90 45 41855 5 0 5 0 36
ASE_00386 0.77 0.59 1.00 57 50346 0 0 0 0 39
ASE_00387 0.63 0.46 0.87 48 55890 7 0 7 0 56
ASE_00388 0.77 0.60 1.00 53 45700 1 0 0 1 36
ASE_00390 0.78 0.62 0.98 53 42141 1 0 1 0 32
ASE_00393 0.71 0.56 0.91 52 47838 5 0 5 0 41
ASE_00394 0.76 0.58 1.00 54 46917 0 0 0 0 39
ASE_00395 0.80 0.64 1.00 54 41562 0 0 0 0 30
ASE_00396 0.81 0.65 1.00 54 41562 0 0 0 0 29
ASE_00397 0.74 0.54 1.00 57 54558 0 0 0 0 48
ASE_00398 0.72 0.52 1.00 54 55891 0 0 0 0 50
ASE_00400 0.72 0.52 1.00 55 57915 1 0 0 1 51
ASE_00401 0.62 0.40 0.96 50 76976 2 1 1 0 76
ASE_00402 0.80 0.65 1.00 55 42431 0 0 0 0 30
ASE_00403 0.73 0.53 1.00 57 55888 0 0 0 0 50
ASE_00404 0.80 0.65 1.00 55 43016 1 0 0 1 30
ASE_00406 0.78 0.61 1.00 57 48771 0 0 0 0 37
ASE_00411 0.67 0.55 0.82 49 49395 11 5 6 0 40
ASE_00412 0.63 0.47 0.84 49 58253 9 2 7 0 56
ASE_00413 0.72 0.57 0.90 46 44500 7 2 3 2 35
ASE_00414 0.58 0.44 0.76 42 46305 13 3 10 0 53
ASE_00415 0.57 0.40 0.80 41 54895 10 0 10 0 62
ASE_00416 0.76 0.61 0.94 78 77338 5 1 4 0 49
ASE_00417 0.80 0.65 0.98 65 54549 1 0 1 0 35
ASE_00418 0.81 0.67 0.98 50 38730 1 0 1 0 25
ASE_00419 0.67 0.50 0.89 51 54889 6 2 4 0 52
ASE_00422 0.74 0.57 0.96 54 46915 3 0 2 1 40
ASE_00423 0.77 0.64 0.93 70 56878 6 0 5 1 39
ASE_00426 0.52 0.41 0.68 44 61010 22 5 16 1 64
ASE_00428 0.77 0.62 0.94 78 76553 5 1 4 0 47
ASE_00430 0.73 0.55 0.98 53 46917 1 0 1 0 44
ASE_00431 0.56 0.44 0.71 42 46301 17 7 10 0 53
ASE_00434 0.74 0.61 0.89 67 68190 14 0 8 6 43
ASE_00437 0.52 0.40 0.67 54 79320 27 0 27 0 81
ASE_00438 0.62 0.42 0.92 49 66013 4 1 3 0 67
ASE_00441 0.65 0.44 0.96 49 64210 3 0 2 1 63
ASE_00447 0.84 0.71 1.00 82 60296 0 0 0 0 34
ASE_00448 0.81 0.69 0.95 77 64180 4 0 4 0 35
ASE_00451 0.79 0.64 0.96 80 70793 3 0 3 0 45
CRW_00013 0.37 0.21 0.65 24 103703 17 1 12 4 91
CRW_00016 0.36 0.20 0.65 24 77384 16 1 12 3 96
CRW_00610 0.51 0.33 0.77 27 36280 11 1 7 3 54
CRW_00613 0.48 0.32 0.71 25 34945 14 0 10 4 53
CRW_00614 0.43 0.30 0.63 17 121744 16 2 8 6 40
CRW_00618 0.41 0.28 0.61 17 56252 12 3 8 1 44
CRW_00619 0.53 0.30 0.92 22 165001 5 0 2 3 51
CRW_00620 0.44 0.29 0.69 18 150949 18 0 8 10 45
CRW_00621 0.40 0.27 0.61 19 153150 14 3 9 2 52
CRW_00623 0.49 0.29 0.83 24 129766 9 1 4 4 59
CRW_00633 0.31 0.17 0.58 18 63515 14 2 11 1 88
CRW_00634 0.35 0.20 0.61 19 64589 20 1 11 8 75
CRW_00670 0.49 0.28 0.89 33 70088 8 0 4 4 87
CRW_00671 0.50 0.28 0.89 33 62798 8 0 4 4 84
CRW_00672 0.51 0.30 0.89 33 72353 8 0 4 4 78
CRW_00674 0.29 0.16 0.54 20 83399 20 6 11 3 104
CRW_00676 0.35 0.17 0.69 20 93499 20 0 9 11 95
CRW_00692 0.39 0.22 0.69 20 68606 20 0 9 11 70
PDB_00827 0.58 0.40 0.84 32 26990 6 1 5 0 49
PDB_00919 0.49 0.35 0.69 36 44201 18 0 16 2 67
RFA_00597 0.73 0.64 0.83 70 97819 19 0 14 5 39
RFA_00598 0.72 0.63 0.81 64 84587 26 0 15 11 37
RFA_00599 0.85 0.73 0.99 81 101393 4 0 1 3 30
RFA_00600 0.79 0.68 0.92 68 120221 15 0 6 9 32
RFA_00601 0.82 0.71 0.95 81 99150 9 0 4 5 33
RFA_00602 0.81 0.71 0.93 82 101387 10 0 6 4 34
TMR_00173 0.12 0.07 0.19 3 42179 23 0 13 10 39
TMR_00357 0.37 0.26 0.52 24 82982 24 7 15 2 68
TMR_00601 0.51 0.38 0.70 16 58973 33 2 5 26 26
TMR_00696 0.44 0.30 0.65 34 85026 19 2 16 1 80

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Performance of IPknot - scored lower in this pairwise comparison

1. Total counts & total scores for IPknot

Total Base Pair Counts
Total TP 16389
Total TN 17461094
Total FP 7681
Total FP CONTRA 945
Total FP INCONS 5357
Total FP COMP 1379
Total FN 12488
Total Scores
MCC 0.640
Average MCC ± 95% Confidence Intervals 0.632 ± 0.017
Sensitivity 0.568
Positive Predictive Value 0.722
Nr of predictions 277

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2. Individual counts for IPknot [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00001 0.76 0.73 0.80 55 34122 20 3 11 6 20
ASE_00002 0.68 0.62 0.75 45 35451 20 2 13 5 28
ASE_00004 0.75 0.66 0.85 64 47820 11 5 6 0 33
ASE_00005 0.59 0.51 0.69 60 57883 30 0 27 3 57
ASE_00006 0.60 0.52 0.70 48 47517 22 3 18 1 45
ASE_00007 0.63 0.55 0.72 60 59602 27 0 23 4 50
ASE_00009 0.71 0.67 0.75 45 26046 15 0 15 0 22
ASE_00012 0.66 0.56 0.78 69 73832 22 5 14 3 54
ASE_00014 0.56 0.50 0.63 53 54201 33 7 24 2 53
ASE_00017 0.28 0.31 0.26 20 50962 71 19 39 13 44
ASE_00018 0.70 0.64 0.77 86 80489 27 0 26 1 48
ASE_00020 0.67 0.58 0.77 73 73825 22 2 20 0 53
ASE_00021 0.70 0.57 0.85 91 104089 21 3 13 5 69
ASE_00022 0.69 0.52 0.93 64 82959 9 0 5 4 60
ASE_00023 0.69 0.59 0.82 75 84163 20 0 17 3 52
ASE_00025 0.39 0.35 0.43 25 78548 82 5 28 49 46
ASE_00026 0.56 0.50 0.63 55 59598 36 3 29 4 55
ASE_00028 0.70 0.60 0.81 76 84572 24 3 15 6 50
ASE_00029 0.68 0.57 0.81 70 82942 16 4 12 0 52
ASE_00030 0.78 0.70 0.87 102 85374 15 3 12 0 43
ASE_00031 0.62 0.54 0.71 68 86640 32 1 27 4 58
ASE_00032 0.68 0.58 0.78 69 80112 22 0 19 3 49
ASE_00033 0.71 0.57 0.88 69 64902 11 0 9 2 52
ASE_00035 0.44 0.30 0.66 35 70447 21 4 14 3 83
ASE_00036 0.58 0.52 0.66 68 75752 37 4 31 2 64
ASE_00037 0.47 0.39 0.57 43 59265 34 0 32 2 67
ASE_00038 0.59 0.53 0.66 54 53546 28 4 24 0 47
ASE_00040 0.51 0.42 0.62 56 78913 38 0 34 4 77
ASE_00041 0.69 0.50 0.96 54 57574 4 0 2 2 54
ASE_00042 0.60 0.51 0.70 74 89994 33 1 31 1 71
ASE_00044 0.70 0.70 0.72 73 54513 34 3 26 5 32
ASE_00046 0.67 0.45 1.00 46 50357 1 0 0 1 57
ASE_00047 0.69 0.52 0.93 67 74233 5 1 4 0 63
ASE_00052 0.61 0.51 0.72 57 61346 26 0 22 4 55
ASE_00053 0.67 0.62 0.74 82 79290 31 6 23 2 51
ASE_00057 0.69 0.59 0.80 79 82116 23 3 17 3 55
ASE_00064 0.68 0.60 0.77 53 45382 22 3 13 6 36
ASE_00066 0.78 0.63 0.95 82 72304 4 0 4 0 48
ASE_00068 0.75 0.60 0.94 51 37621 3 0 3 0 34
ASE_00069 0.65 0.56 0.76 78 82926 26 4 20 2 62
ASE_00074 0.49 0.45 0.54 53 67798 45 4 41 0 66
ASE_00075 0.71 0.61 0.83 99 108691 25 2 19 4 63
ASE_00076 0.60 0.53 0.68 63 68173 31 3 26 2 55
ASE_00077 0.68 0.53 0.87 46 45097 12 2 5 5 40
ASE_00078 0.70 0.57 0.87 47 43017 7 1 6 0 36
ASE_00079 0.61 0.54 0.68 54 55532 25 2 23 0 46
ASE_00080 0.41 0.36 0.47 44 71537 54 5 45 4 79
ASE_00081 0.79 0.71 0.88 69 49692 10 1 8 1 28
ASE_00082 0.83 0.74 0.93 86 70408 18 0 6 12 30
ASE_00083 0.77 0.72 0.82 79 62385 22 0 17 5 31
ASE_00084 0.83 0.74 0.94 73 53550 8 1 4 3 26
ASE_00087 0.74 0.63 0.87 90 88306 14 2 12 0 54
ASE_00090 0.66 0.58 0.75 59 55532 20 1 19 0 42
ASE_00092 0.85 0.78 0.93 88 63451 9 1 6 2 25
ASE_00096 0.59 0.52 0.67 60 63456 30 3 27 0 55
ASE_00099 0.80 0.70 0.92 84 64529 7 0 7 0 36
ASE_00100 0.29 0.25 0.33 19 82158 85 2 36 47 57
ASE_00102 0.72 0.65 0.81 108 117721 29 5 21 3 58
ASE_00104 0.75 0.66 0.84 79 64167 15 2 13 0 40
ASE_00105 0.48 0.41 0.56 46 64179 39 6 30 3 65
ASE_00107 0.73 0.66 0.82 84 73050 19 1 18 0 43
ASE_00108 0.45 0.43 0.47 27 46913 62 5 26 31 36
ASE_00111 0.16 0.14 0.18 8 50041 46 12 25 9 49
ASE_00112 0.80 0.67 0.95 78 75384 10 1 3 6 38
ASE_00115 0.74 0.68 0.81 69 54530 23 4 12 7 32
ASE_00116 0.32 0.24 0.42 16 31588 25 1 21 3 50
ASE_00118 0.40 0.37 0.44 38 60639 50 3 46 1 64
ASE_00119 0.85 0.81 0.91 87 62739 9 1 8 0 21
ASE_00120 0.62 0.55 0.69 52 46896 23 7 16 0 42
ASE_00121 0.43 0.37 0.51 34 45083 34 4 29 1 58
ASE_00122 0.73 0.65 0.83 57 43296 12 0 12 0 31
ASE_00123 0.52 0.49 0.55 42 38427 38 2 32 4 43
ASE_00125 0.75 0.65 0.86 57 39274 11 0 9 2 31
ASE_00128 0.78 0.65 0.94 65 53232 7 0 4 3 35
ASE_00129 0.70 0.67 0.74 74 62735 27 5 21 1 37
ASE_00131 0.80 0.66 0.98 56 39283 5 0 1 4 29
ASE_00132 0.63 0.48 0.82 46 50347 11 1 9 1 49
ASE_00134 0.51 0.47 0.55 45 50321 37 4 33 0 50
ASE_00135 0.67 0.58 0.79 63 63110 22 1 16 5 46
ASE_00136 0.61 0.52 0.72 48 48138 28 1 18 9 44
ASE_00137 0.75 0.68 0.82 67 48434 15 0 15 0 31
ASE_00138 0.58 0.48 0.70 39 40414 17 1 16 0 42
ASE_00139 0.73 0.63 0.84 66 54206 15 0 13 2 38
ASE_00140 0.72 0.61 0.85 76 70787 14 3 10 1 49
ASE_00142 0.73 0.65 0.81 79 67064 19 4 14 1 43
ASE_00145 0.63 0.53 0.75 59 70046 24 5 15 4 52
ASE_00146 0.55 0.43 0.72 53 70802 22 5 16 1 71
ASE_00148 0.74 0.69 0.80 106 112443 26 3 23 0 48
ASE_00151 0.52 0.49 0.55 48 51916 41 9 30 2 50
ASE_00153 0.52 0.51 0.54 37 57562 60 6 25 29 36
ASE_00154 0.70 0.64 0.76 68 65252 24 2 19 3 39
ASE_00155 0.58 0.52 0.64 74 93412 45 4 38 3 68
ASE_00163 0.39 0.35 0.43 33 53224 53 4 40 9 60
ASE_00165 0.65 0.55 0.77 56 52902 18 4 13 1 45
ASE_00168 0.28 0.31 0.26 20 60648 74 18 40 16 44
ASE_00169 0.52 0.44 0.62 47 57215 30 0 29 1 60
ASE_00170 0.63 0.55 0.73 51 48758 20 3 16 1 42
ASE_00171 0.71 0.67 0.76 63 48433 20 4 16 0 31
ASE_00172 0.81 0.71 0.94 75 58916 5 1 4 0 31
ASE_00174 0.63 0.60 0.66 65 60977 33 8 25 0 44
ASE_00175 0.62 0.55 0.70 59 59947 26 2 23 1 48
ASE_00176 0.45 0.42 0.49 46 59937 50 6 42 2 64
ASE_00179 0.65 0.56 0.75 47 44190 18 2 14 2 37
ASE_00180 0.69 0.56 0.85 56 51294 10 2 8 0 44
ASE_00181 0.60 0.53 0.67 56 57547 31 0 27 4 50
ASE_00182 0.57 0.53 0.62 72 84139 44 3 41 0 64
ASE_00184 0.71 0.70 0.73 71 54518 26 4 22 0 31
ASE_00185 0.79 0.69 0.92 88 73440 10 0 8 2 40
ASE_00186 0.74 0.68 0.81 90 78892 26 1 20 5 42
ASE_00187 0.53 0.43 0.65 49 68560 28 2 24 2 66
ASE_00189 0.72 0.58 0.91 59 63125 8 1 5 2 43
ASE_00190 0.75 0.58 0.98 52 45398 3 0 1 2 38
ASE_00192 0.71 0.62 0.80 83 84562 26 2 19 5 50
ASE_00194 0.53 0.45 0.64 53 73453 34 0 30 4 66
ASE_00196 0.76 0.75 0.78 56 31554 20 2 14 4 19
ASE_00197 0.67 0.57 0.78 83 89147 28 1 22 5 62
ASE_00203 0.77 0.69 0.87 66 46589 10 1 9 0 30
ASE_00204 0.64 0.45 0.93 50 67842 8 0 4 4 62
ASE_00205 0.53 0.49 0.59 44 45981 33 6 25 2 46
ASE_00209 0.53 0.49 0.58 43 42997 31 5 26 0 45
ASE_00210 0.58 0.58 0.58 38 27195 30 7 21 2 27
ASE_00212 0.73 0.68 0.79 101 93833 31 3 24 4 47
ASE_00213 0.77 0.67 0.90 44 27212 5 1 4 0 22
ASE_00214 0.80 0.78 0.83 80 56184 23 3 13 7 23
ASE_00215 0.48 0.41 0.56 41 48443 32 1 31 0 58
ASE_00216 0.66 0.62 0.70 51 39267 22 3 19 0 31
ASE_00217 0.34 0.29 0.41 26 40406 39 7 31 1 64
ASE_00221 0.61 0.46 0.82 54 64554 12 1 11 0 63
ASE_00222 0.66 0.62 0.70 98 111961 42 4 38 0 59
ASE_00227 0.33 0.29 0.37 39 78897 67 5 62 0 94
ASE_00228 0.78 0.74 0.82 64 46893 16 6 8 2 22
ASE_00229 0.73 0.63 0.83 55 42420 12 3 8 1 32
ASE_00231 0.74 0.66 0.83 63 47819 13 3 10 0 33
ASE_00232 0.80 0.77 0.82 65 38424 14 7 7 0 19
ASE_00234 0.58 0.49 0.70 63 75376 31 2 25 4 66
ASE_00237 0.00 0.00 0.00 0 45686 81 18 49 14 56
ASE_00238 0.64 0.54 0.75 62 64178 22 1 20 1 52
ASE_00240 0.59 0.54 0.64 50 46587 30 1 27 2 43
ASE_00241 0.72 0.60 0.87 52 43896 8 1 7 0 35
ASE_00242 0.73 0.59 0.92 66 61003 6 1 5 0 46
ASE_00246 0.38 0.34 0.43 23 48151 40 6 25 9 44
ASE_00247 0.27 0.30 0.25 19 54209 72 17 40 15 45
ASE_00248 0.71 0.61 0.84 69 62399 15 0 13 2 45
ASE_00250 0.67 0.53 0.85 69 78922 15 4 8 3 62
ASE_00252 0.77 0.64 0.92 108 115323 13 0 9 4 60
ASE_00254 0.76 0.68 0.85 56 36790 15 3 7 5 26
ASE_00255 0.72 0.62 0.85 80 74597 14 3 11 0 50
ASE_00257 0.76 0.63 0.91 61 50973 6 1 5 0 36
ASE_00263 0.70 0.62 0.80 74 70407 19 3 16 0 46
ASE_00264 0.53 0.49 0.57 49 49055 45 1 36 8 51
ASE_00267 0.54 0.42 0.70 37 45097 22 0 16 6 51
ASE_00270 0.76 0.73 0.79 93 72273 26 1 23 2 35
ASE_00274 0.64 0.55 0.75 57 55535 19 5 14 0 46
ASE_00277 0.59 0.53 0.66 48 48132 25 4 21 0 43
ASE_00279 0.73 0.62 0.86 63 53228 10 3 7 0 38
ASE_00280 0.70 0.61 0.81 60 51929 15 1 13 1 38
ASE_00281 0.82 0.74 0.90 65 44479 13 0 7 6 23
ASE_00282 0.55 0.51 0.60 65 77706 44 6 38 0 62
ASE_00283 0.77 0.72 0.83 77 61683 16 5 11 0 30
ASE_00284 0.69 0.68 0.72 73 58209 34 5 24 5 35
ASE_00285 0.80 0.75 0.86 91 68900 23 3 12 8 31
ASE_00286 0.67 0.57 0.80 52 46600 17 1 12 4 40
ASE_00287 0.72 0.69 0.76 71 54853 23 2 20 1 32
ASE_00288 0.77 0.59 1.00 55 46001 0 0 0 0 38
ASE_00289 0.79 0.69 0.90 109 100904 15 5 7 3 48
ASE_00292 0.68 0.60 0.76 83 81701 27 2 24 1 55
ASE_00294 0.78 0.68 0.90 117 114351 14 1 12 1 54
ASE_00295 0.72 0.63 0.84 82 73822 16 3 13 0 49
ASE_00296 0.48 0.43 0.53 63 91688 56 5 50 1 82
ASE_00297 0.68 0.62 0.74 61 52893 21 3 18 0 37
ASE_00298 0.57 0.51 0.64 58 67438 34 1 31 2 55
ASE_00299 0.63 0.56 0.72 56 49377 27 1 21 5 44
ASE_00313 0.69 0.66 0.71 59 62398 44 4 20 20 30
ASE_00316 0.78 0.63 0.97 62 107816 35 0 2 33 36
ASE_00318 0.52 0.43 0.64 51 80120 32 4 25 3 67
ASE_00327 0.74 0.72 0.76 64 57207 25 6 14 5 25
ASE_00328 0.70 0.60 0.83 67 72690 20 4 10 6 45
ASE_00330 0.75 0.71 0.79 64 56199 35 0 17 18 26
ASE_00332 0.55 0.50 0.60 69 81695 47 2 44 1 69
ASE_00335 0.68 0.59 0.78 68 75379 25 2 17 6 48
ASE_00337 0.60 0.59 0.62 42 39272 39 5 21 13 29
ASE_00338 0.77 0.68 0.87 67 66353 26 3 7 16 31
ASE_00339 0.72 0.63 0.82 75 80108 26 0 17 9 44
ASE_00340 0.76 0.75 0.77 64 45973 25 8 11 6 21
ASE_00342 0.75 0.68 0.83 78 62387 17 1 15 1 37
ASE_00343 0.77 0.67 0.87 76 83349 21 0 11 10 37
ASE_00346 0.37 0.34 0.40 33 48123 51 3 46 2 64
ASE_00353 0.57 0.51 0.63 55 57882 35 4 29 2 52
ASE_00359 0.51 0.43 0.61 34 42722 22 3 19 0 46
ASE_00360 0.50 0.45 0.57 29 29352 22 3 19 0 36
ASE_00361 0.53 0.47 0.59 60 75364 45 9 33 3 67
ASE_00362 0.66 0.59 0.74 54 48132 20 2 17 1 37
ASE_00363 0.76 0.64 0.91 60 51294 7 0 6 1 34
ASE_00364 0.63 0.56 0.70 59 54201 25 3 22 0 46
ASE_00366 0.54 0.51 0.58 50 58567 36 5 31 0 48
ASE_00367 0.62 0.55 0.71 47 43005 23 5 14 4 39
ASE_00369 0.73 0.71 0.75 76 55843 27 0 26 1 31
ASE_00370 0.49 0.43 0.55 36 41840 29 1 28 0 48
ASE_00372 0.74 0.68 0.80 68 51918 20 3 14 3 32
ASE_00374 0.64 0.61 0.68 54 44770 26 5 21 0 34
ASE_00375 0.79 0.70 0.89 77 60291 10 1 9 0 33
ASE_00376 0.62 0.57 0.68 60 56865 30 5 23 2 45
ASE_00377 0.77 0.74 0.81 79 57532 24 3 16 5 28
ASE_00379 0.70 0.62 0.79 55 45986 16 5 10 1 34
ASE_00380 0.54 0.49 0.59 49 54863 35 4 30 1 50
ASE_00382 0.69 0.58 0.82 49 41845 14 5 6 3 35
ASE_00383 0.71 0.64 0.80 67 54531 19 5 12 2 38
ASE_00384 0.73 0.71 0.76 65 48430 25 1 20 4 27
ASE_00385 0.63 0.56 0.73 45 41843 17 7 10 0 36
ASE_00386 0.65 0.60 0.70 58 50320 30 1 24 5 38
ASE_00387 0.75 0.65 0.86 68 55866 13 1 10 2 36
ASE_00388 0.74 0.61 0.90 54 45693 7 0 6 1 35
ASE_00390 0.77 0.71 0.85 60 42124 18 0 11 7 25
ASE_00393 0.72 0.65 0.81 60 47821 15 0 14 1 33
ASE_00394 0.80 0.76 0.85 71 46887 14 3 10 1 22
ASE_00395 0.77 0.73 0.81 61 41541 14 2 12 0 23
ASE_00396 0.68 0.61 0.76 51 41549 18 5 11 2 32
ASE_00397 0.81 0.72 0.92 76 54532 7 2 5 0 29
ASE_00398 0.65 0.59 0.72 61 55860 25 1 23 1 43
ASE_00400 0.74 0.65 0.83 69 57887 15 1 13 1 37
ASE_00401 0.64 0.60 0.68 75 76918 35 5 30 0 51
ASE_00402 0.68 0.60 0.77 51 42420 15 4 11 0 34
ASE_00403 0.57 0.47 0.69 50 55873 22 0 22 0 57
ASE_00404 0.58 0.51 0.66 43 43006 22 1 21 0 42
ASE_00406 0.74 0.64 0.87 60 48759 11 0 9 2 34
ASE_00411 0.59 0.46 0.75 41 49400 15 5 9 1 48
ASE_00412 0.56 0.47 0.67 49 58238 24 7 17 0 56
ASE_00413 0.47 0.46 0.49 37 44475 42 5 34 3 44
ASE_00414 0.46 0.40 0.52 38 46287 42 2 33 7 57
ASE_00415 0.70 0.65 0.74 67 54856 28 1 22 5 36
ASE_00416 0.71 0.60 0.84 76 77330 20 0 15 5 51
ASE_00417 0.43 0.41 0.46 41 54525 53 4 45 4 59
ASE_00418 0.20 0.19 0.21 14 38714 55 2 51 2 61
ASE_00419 0.78 0.74 0.83 76 54854 17 3 13 1 27
ASE_00422 0.69 0.65 0.74 61 46889 26 6 15 5 33
ASE_00423 0.65 0.64 0.66 70 56847 36 6 30 0 39
ASE_00426 0.59 0.52 0.68 56 60993 26 1 25 0 52
ASE_00428 0.65 0.59 0.72 74 76533 33 2 27 4 51
ASE_00430 0.76 0.68 0.85 66 46893 17 3 9 5 31
ASE_00431 0.71 0.61 0.82 58 46289 18 1 12 5 37
ASE_00434 0.70 0.60 0.81 66 68184 23 3 12 8 44
ASE_00437 0.55 0.41 0.74 56 79325 20 0 20 0 79
ASE_00438 0.69 0.59 0.79 69 65979 18 0 18 0 47
ASE_00441 0.79 0.72 0.86 81 64167 15 2 11 2 31
ASE_00447 0.67 0.59 0.77 68 60290 25 0 20 5 48
ASE_00448 0.53 0.42 0.66 47 64190 30 4 20 6 65
ASE_00451 0.75 0.66 0.85 82 70780 14 2 12 0 43
CRW_00013 0.33 0.26 0.42 30 103669 55 7 34 14 85
CRW_00016 0.75 0.67 0.83 80 77325 26 6 10 10 40
CRW_00610 0.61 0.54 0.68 44 36250 21 6 15 0 37
CRW_00613 0.86 0.78 0.94 61 34915 13 1 3 9 17
CRW_00614 0.13 0.14 0.13 8 121707 95 15 41 39 49
CRW_00618 0.25 0.25 0.26 15 56223 56 5 37 14 46
CRW_00619 0.42 0.30 0.58 22 164987 82 4 12 66 51
CRW_00620 0.20 0.21 0.19 13 150907 93 14 41 38 50
CRW_00621 0.35 0.31 0.39 22 153125 120 4 30 86 49
CRW_00623 0.30 0.23 0.39 19 129746 89 5 25 59 64
CRW_00633 0.64 0.58 0.72 61 63461 25 5 19 1 45
CRW_00634 0.60 0.56 0.65 53 64538 30 10 19 1 41
CRW_00670 0.83 0.78 0.87 94 70017 14 6 8 0 26
CRW_00671 0.82 0.74 0.92 86 62742 8 1 6 1 31
CRW_00672 0.76 0.72 0.80 80 72290 24 8 12 4 31
CRW_00674 0.75 0.69 0.83 85 83333 20 7 11 2 39
CRW_00676 0.47 0.44 0.51 51 93428 52 14 35 3 64
CRW_00692 0.56 0.47 0.68 42 68573 21 7 13 1 48
PDB_00827 0.79 0.65 0.95 53 26972 5 0 3 2 28
PDB_00919 0.53 0.47 0.62 48 44175 34 2 28 4 55
RFA_00597 0.52 0.50 0.55 54 97804 55 4 41 10 55
RFA_00598 0.49 0.48 0.51 48 84572 68 5 41 22 53
RFA_00599 0.75 0.73 0.77 81 101370 40 8 16 16 30
RFA_00600 0.22 0.22 0.21 22 120191 99 29 53 17 78
RFA_00601 0.45 0.46 0.43 53 99113 82 25 44 13 61
RFA_00602 0.42 0.43 0.40 50 101351 83 20 54 9 66
TMR_00173 0.50 0.40 0.63 17 42168 32 2 8 22 25
TMR_00357 0.52 0.49 0.56 45 82948 53 16 19 18 47
TMR_00601 0.61 0.48 0.77 20 58970 37 0 6 31 22
TMR_00696 0.51 0.50 0.53 57 84970 62 9 42 11 57

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.