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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

  4. Performance of McQFold - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(seed) & McQFold [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(seed) McQFold
MCC 0.691 > 0.479
Average MCC ± 95% Confidence Intervals 0.688 ± 0.015 > 0.478 ± 0.018
Sensitivity 0.521 > 0.458
Positive Predictive Value 0.919 > 0.502
Total TP 15031 > 13240
Total TN 17467425 > 17457424
Total FP 1662 < 14834
Total FP CONTRA 179 < 1674
Total FP INCONS 1150 < 11447
Total FP COMP 333 < 1713
Total FN 13846 < 15637
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of CentroidAlifold(seed) and McQFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(seed) and McQFold).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for CentroidAlifold(seed) and McQFold).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(seed) and McQFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(seed) and McQFold).

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Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(seed)

Total Base Pair Counts
Total TP 15031
Total TN 17467425
Total FP 1662
Total FP CONTRA 179
Total FP INCONS 1150
Total FP COMP 333
Total FN 13846
Total Scores
MCC 0.691
Average MCC ± 95% Confidence Intervals 0.688 ± 0.015
Sensitivity 0.521
Positive Predictive Value 0.919
Nr of predictions 277

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2. Individual counts for CentroidAlifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00001 0.81 0.65 1.00 49 34142 0 0 0 0 26
ASE_00002 0.82 0.67 1.00 49 35462 0 0 0 0 24
ASE_00004 0.61 0.45 0.83 44 47842 9 0 9 0 53
ASE_00005 0.75 0.57 0.97 67 57901 2 0 2 0 50
ASE_00006 0.58 0.44 0.76 41 47532 13 0 13 0 52
ASE_00007 0.83 0.71 0.98 78 59605 2 0 2 0 32
ASE_00009 0.79 0.67 0.94 45 26058 3 0 3 0 22
ASE_00012 0.75 0.59 0.95 73 73843 7 1 3 3 50
ASE_00014 0.74 0.58 0.95 61 54221 3 0 3 0 45
ASE_00017 0.79 0.69 0.90 44 50991 5 1 4 0 20
ASE_00018 0.78 0.60 1.00 81 80520 0 0 0 0 53
ASE_00020 0.63 0.43 0.93 54 73862 4 3 1 0 72
ASE_00021 0.63 0.44 0.90 71 104117 11 2 6 3 89
ASE_00022 0.80 0.65 1.00 80 82948 5 0 0 5 44
ASE_00023 0.47 0.35 0.63 45 84184 28 8 18 2 82
ASE_00025 0.69 0.58 0.84 41 78557 8 1 7 0 30
ASE_00026 0.80 0.67 0.96 74 59608 4 0 3 1 36
ASE_00028 0.80 0.64 1.00 81 84585 3 0 0 3 45
ASE_00029 0.45 0.34 0.61 41 82961 30 4 22 4 81
ASE_00030 0.66 0.49 0.90 71 85412 8 0 8 0 74
ASE_00031 0.51 0.37 0.72 46 86672 18 0 18 0 80
ASE_00032 0.38 0.27 0.54 32 80141 30 1 26 3 86
ASE_00033 0.80 0.65 0.99 79 64900 3 1 0 2 42
ASE_00035 0.77 0.64 0.94 75 70420 8 0 5 3 43
ASE_00036 0.75 0.58 0.99 76 75778 1 1 0 0 56
ASE_00037 0.84 0.71 1.00 78 59262 1 0 0 1 32
ASE_00038 0.74 0.54 1.00 55 53573 0 0 0 0 46
ASE_00040 0.77 0.59 1.00 79 78924 2 0 0 2 54
ASE_00041 0.77 0.64 0.92 69 57555 6 0 6 0 39
ASE_00042 0.65 0.49 0.87 71 90018 11 0 11 0 74
ASE_00044 0.83 0.70 1.00 73 54542 0 0 0 0 32
ASE_00046 0.73 0.62 0.86 64 50329 10 0 10 0 39
ASE_00047 0.70 0.52 0.93 68 74232 5 0 5 0 62
ASE_00052 0.75 0.63 0.91 70 61348 8 0 7 1 42
ASE_00053 0.71 0.54 0.92 72 79323 6 3 3 0 61
ASE_00057 0.73 0.57 0.93 77 82132 6 2 4 0 57
ASE_00064 0.77 0.60 1.00 53 45398 0 0 0 0 36
ASE_00066 0.75 0.56 1.00 73 72317 1 0 0 1 57
ASE_00068 0.54 0.38 0.78 32 37634 9 0 9 0 53
ASE_00069 0.75 0.57 0.98 80 82946 3 0 2 1 60
ASE_00074 0.83 0.69 1.00 82 67814 1 0 0 1 37
ASE_00075 0.64 0.44 0.92 71 108734 11 1 5 5 91
ASE_00076 0.69 0.48 1.00 57 68208 0 0 0 0 61
ASE_00077 0.79 0.64 0.96 55 45093 2 1 1 0 31
ASE_00078 0.83 0.69 1.00 57 43014 0 0 0 0 26
ASE_00079 0.63 0.47 0.84 47 55555 9 0 9 0 53
ASE_00080 0.45 0.30 0.66 37 71575 19 1 18 0 86
ASE_00081 0.77 0.59 1.00 57 49713 0 0 0 0 40
ASE_00082 0.66 0.43 1.00 50 70450 6 0 0 6 66
ASE_00083 0.72 0.52 1.00 57 62424 0 0 0 0 53
ASE_00084 0.75 0.57 0.98 56 53571 1 1 0 0 43
ASE_00087 0.60 0.38 0.95 54 88353 3 0 3 0 90
ASE_00090 0.75 0.56 1.00 57 55554 0 0 0 0 44
ASE_00092 0.70 0.50 0.98 56 63489 1 1 0 0 57
ASE_00096 0.63 0.44 0.89 51 63489 6 0 6 0 64
ASE_00099 0.82 0.67 1.00 80 64540 0 0 0 0 40
ASE_00100 0.72 0.58 0.90 44 82166 5 1 4 0 32
ASE_00102 0.57 0.40 0.81 66 117774 15 1 14 0 100
ASE_00104 0.81 0.67 0.99 80 64180 1 0 1 0 39
ASE_00105 0.55 0.40 0.76 44 64203 14 4 10 0 67
ASE_00107 0.78 0.63 0.96 80 73070 3 0 3 0 47
ASE_00108 0.79 0.70 0.90 44 46922 5 1 4 0 19
ASE_00111 0.83 0.74 0.93 42 50041 3 1 2 0 15
ASE_00112 0.50 0.34 0.71 40 75410 16 0 16 0 76
ASE_00115 0.74 0.54 1.00 55 54560 0 0 0 0 46
ASE_00116 0.86 0.76 0.98 50 31575 1 0 1 0 16
ASE_00118 0.68 0.49 0.94 50 60673 4 1 2 1 52
ASE_00119 0.66 0.44 0.98 48 62786 1 1 0 0 60
ASE_00120 0.79 0.64 0.98 60 46910 2 0 1 1 34
ASE_00121 0.81 0.66 0.98 61 45088 1 0 1 0 31
ASE_00122 0.80 0.64 1.00 56 43309 1 0 0 1 32
ASE_00123 0.68 0.48 0.95 41 38460 2 0 2 0 44
ASE_00125 0.67 0.47 0.95 41 39297 2 0 2 0 47
ASE_00128 0.73 0.54 1.00 54 53247 0 0 0 0 46
ASE_00129 0.71 0.50 1.00 56 62779 0 0 0 0 55
ASE_00131 0.65 0.44 0.97 37 39302 1 1 0 0 48
ASE_00132 0.76 0.59 0.98 56 50346 1 1 0 0 39
ASE_00134 0.69 0.54 0.89 51 50346 6 0 6 0 44
ASE_00135 0.53 0.39 0.74 42 63133 15 0 15 0 67
ASE_00136 0.75 0.59 0.95 54 48148 3 0 3 0 38
ASE_00137 0.70 0.53 0.93 52 48460 4 0 4 0 46
ASE_00138 0.79 0.63 1.00 51 40419 0 0 0 0 30
ASE_00139 0.73 0.54 1.00 56 54229 0 0 0 0 48
ASE_00140 0.64 0.43 0.95 54 70819 3 3 0 0 71
ASE_00142 0.77 0.61 0.97 75 67084 4 0 2 2 47
ASE_00145 0.77 0.59 1.00 66 70059 0 0 0 0 45
ASE_00146 0.78 0.62 0.97 77 70797 2 0 2 0 47
ASE_00148 0.62 0.41 0.95 63 112509 3 0 3 0 91
ASE_00151 0.80 0.70 0.92 69 51928 6 5 1 0 29
ASE_00153 0.67 0.53 0.85 39 57584 7 1 6 0 34
ASE_00154 0.75 0.59 0.95 63 65275 3 0 3 0 44
ASE_00155 0.68 0.46 1.00 66 93462 0 0 0 0 76
ASE_00163 0.77 0.59 1.00 55 53246 0 0 0 0 38
ASE_00165 0.69 0.50 0.94 51 52921 4 1 2 1 50
ASE_00168 0.79 0.69 0.90 44 60677 5 1 4 0 20
ASE_00169 0.65 0.48 0.88 51 57233 7 1 6 0 56
ASE_00170 0.78 0.60 1.00 56 48772 0 0 0 0 37
ASE_00171 0.76 0.59 1.00 55 48461 1 0 0 1 39
ASE_00172 0.72 0.53 0.98 56 58939 1 1 0 0 50
ASE_00174 0.60 0.43 0.82 47 61018 10 1 9 0 62
ASE_00175 0.71 0.51 0.98 55 59975 1 1 0 0 52
ASE_00176 0.71 0.50 1.00 55 59976 0 0 0 0 55
ASE_00179 0.79 0.63 0.98 53 44199 2 0 1 1 31
ASE_00180 0.73 0.54 0.98 54 51305 1 1 0 0 46
ASE_00181 0.71 0.52 0.96 55 57573 3 2 0 1 51
ASE_00182 0.61 0.40 0.95 54 84198 3 0 3 0 82
ASE_00184 0.75 0.56 1.00 57 54558 0 0 0 0 45
ASE_00185 0.64 0.41 0.98 53 73482 1 1 0 0 75
ASE_00186 0.66 0.51 0.86 67 78925 14 0 11 3 65
ASE_00187 0.69 0.51 0.92 59 68571 5 1 4 0 56
ASE_00189 0.76 0.62 0.94 63 63123 8 0 4 4 39
ASE_00190 0.74 0.54 1.00 49 45402 3 0 0 3 41
ASE_00192 0.51 0.35 0.75 47 84603 20 0 16 4 86
ASE_00194 0.72 0.53 0.97 63 73471 7 0 2 5 56
ASE_00196 0.82 0.69 0.96 52 31572 2 0 2 0 23
ASE_00197 0.63 0.46 0.86 67 89175 12 0 11 1 78
ASE_00203 0.72 0.55 0.93 53 46608 4 2 2 0 43
ASE_00204 0.73 0.55 0.97 62 67832 7 1 1 5 50
ASE_00205 0.82 0.67 1.00 60 45996 1 0 0 1 30
ASE_00209 0.83 0.69 0.98 61 43009 1 0 1 0 27
ASE_00210 0.74 0.65 0.86 42 27212 9 0 7 2 23
ASE_00212 0.63 0.45 0.89 66 93887 9 0 8 1 82
ASE_00213 0.83 0.71 0.98 47 27213 3 0 1 2 19
ASE_00214 0.73 0.54 0.98 56 56223 2 1 0 1 47
ASE_00215 0.51 0.32 0.82 32 48477 7 0 7 0 67
ASE_00216 0.81 0.66 1.00 54 39286 0 0 0 0 28
ASE_00217 0.82 0.67 1.00 60 40410 1 0 0 1 30
ASE_00221 0.83 0.70 0.99 82 64537 1 0 1 0 35
ASE_00222 0.65 0.42 1.00 66 112035 0 0 0 0 91
ASE_00227 0.57 0.43 0.76 57 78928 18 0 18 0 76
ASE_00228 0.72 0.57 0.91 49 46917 6 3 2 1 37
ASE_00229 0.78 0.61 1.00 53 42433 2 0 0 2 34
ASE_00231 0.59 0.45 0.78 43 47840 12 0 12 0 53
ASE_00232 0.81 0.65 1.00 55 38448 0 0 0 0 29
ASE_00234 0.64 0.43 0.95 55 75408 3 3 0 0 74
ASE_00237 0.83 0.73 0.93 41 45709 3 1 2 0 15
ASE_00238 0.61 0.44 0.86 50 64203 8 2 6 0 64
ASE_00240 0.62 0.48 0.79 45 46608 12 0 12 0 48
ASE_00241 0.79 0.64 0.98 56 43899 1 0 1 0 31
ASE_00242 0.85 0.72 1.00 81 60994 1 0 0 1 31
ASE_00246 0.79 0.67 0.92 45 48156 4 1 3 0 22
ASE_00247 0.79 0.69 0.90 44 54236 5 1 4 0 20
ASE_00248 0.84 0.71 1.00 81 62400 1 0 0 1 33
ASE_00250 0.72 0.56 0.91 74 78922 8 1 6 1 57
ASE_00252 0.63 0.43 0.92 72 115362 10 2 4 4 96
ASE_00254 0.81 0.66 1.00 54 36802 0 0 0 0 28
ASE_00255 0.64 0.51 0.80 66 74609 16 0 16 0 64
ASE_00257 0.68 0.52 0.91 50 50985 5 1 4 0 47
ASE_00263 0.68 0.47 0.98 56 70443 1 1 0 0 64
ASE_00264 0.58 0.40 0.85 40 49094 8 0 7 1 60
ASE_00267 0.80 0.64 1.00 56 45094 0 0 0 0 32
ASE_00270 0.55 0.34 0.90 43 72342 6 0 5 1 85
ASE_00274 0.71 0.53 0.95 55 55553 3 3 0 0 48
ASE_00277 0.73 0.57 0.93 52 48149 4 3 1 0 39
ASE_00279 0.73 0.54 0.98 55 53245 1 0 1 0 46
ASE_00280 0.74 0.57 0.97 56 51945 2 1 1 0 42
ASE_00281 0.78 0.63 0.98 55 44495 1 0 1 0 33
ASE_00282 0.66 0.45 0.98 57 77757 1 1 0 0 70
ASE_00283 0.72 0.52 0.98 56 61719 1 0 1 0 51
ASE_00284 0.72 0.53 0.98 57 58253 1 1 0 0 51
ASE_00285 0.68 0.47 1.00 57 68949 0 0 0 0 65
ASE_00286 0.78 0.61 1.00 56 46609 0 0 0 0 36
ASE_00287 0.67 0.50 0.89 51 54889 6 0 6 0 52
ASE_00288 0.75 0.58 0.96 54 46000 2 2 0 0 39
ASE_00289 0.66 0.46 0.95 73 100948 4 0 4 0 84
ASE_00292 0.76 0.58 1.00 80 81730 1 0 0 1 58
ASE_00294 0.68 0.47 0.98 81 114398 2 0 2 0 90
ASE_00295 0.77 0.59 1.00 77 73843 0 0 0 0 54
ASE_00296 0.73 0.54 0.98 79 91725 3 0 2 1 66
ASE_00297 0.61 0.45 0.83 44 52922 9 2 7 0 54
ASE_00298 0.70 0.50 0.98 56 67471 1 1 0 0 57
ASE_00299 0.55 0.44 0.70 44 49392 19 0 19 0 56
ASE_00313 0.50 0.34 0.75 30 62441 14 2 8 4 59
ASE_00316 0.46 0.27 0.79 26 107847 8 0 7 1 72
ASE_00318 0.79 0.62 1.00 73 80127 6 0 0 6 45
ASE_00327 0.61 0.43 0.86 38 57247 11 0 6 5 51
ASE_00328 0.83 0.70 1.00 78 72693 5 0 0 5 34
ASE_00330 0.66 0.48 0.91 43 56233 5 0 4 1 47
ASE_00332 0.78 0.60 1.00 83 81727 0 0 0 0 55
ASE_00335 0.81 0.66 1.00 77 75389 7 0 0 7 39
ASE_00337 0.57 0.44 0.76 31 39299 18 0 10 8 40
ASE_00338 0.51 0.33 0.80 32 66390 8 0 8 0 66
ASE_00339 0.58 0.46 0.72 55 80124 22 7 14 1 64
ASE_00340 0.73 0.56 0.94 48 46005 7 0 3 4 37
ASE_00342 0.84 0.71 1.00 82 62399 0 0 0 0 33
ASE_00343 0.37 0.27 0.51 31 83375 32 2 28 2 82
ASE_00346 0.61 0.49 0.75 48 48141 16 0 16 0 49
ASE_00353 0.72 0.52 0.98 56 57913 2 1 0 1 51
ASE_00359 0.77 0.61 0.98 49 42728 2 0 1 1 31
ASE_00360 0.87 0.77 0.98 50 29352 1 0 1 0 15
ASE_00361 0.65 0.43 0.98 55 75410 1 1 0 0 72
ASE_00362 0.78 0.62 1.00 56 48149 1 0 0 1 35
ASE_00363 0.70 0.54 0.89 51 51303 6 0 6 0 43
ASE_00364 0.66 0.49 0.89 51 54228 6 1 5 0 54
ASE_00366 0.69 0.53 0.90 52 58595 6 2 4 0 46
ASE_00367 0.81 0.65 1.00 56 43015 1 0 0 1 30
ASE_00369 0.73 0.53 1.00 57 55888 0 0 0 0 50
ASE_00370 0.78 0.62 0.98 52 41852 1 0 1 0 32
ASE_00372 0.73 0.54 0.98 54 51948 1 0 1 0 46
ASE_00374 0.78 0.60 1.00 53 44797 0 0 0 0 35
ASE_00375 0.71 0.51 1.00 56 60322 1 0 0 1 54
ASE_00376 0.68 0.50 0.93 53 56896 4 0 4 0 52
ASE_00377 0.67 0.50 0.91 53 57572 5 1 4 0 54
ASE_00379 0.79 0.63 1.00 56 46000 1 0 0 1 33
ASE_00380 0.75 0.57 1.00 56 54890 0 0 0 0 43
ASE_00382 0.80 0.64 1.00 54 41851 1 0 0 1 30
ASE_00383 0.74 0.54 1.00 57 54558 0 0 0 0 48
ASE_00384 0.78 0.61 1.00 56 48460 0 0 0 0 36
ASE_00385 0.71 0.56 0.90 45 41855 5 0 5 0 36
ASE_00386 0.77 0.59 1.00 57 50346 0 0 0 0 39
ASE_00387 0.63 0.46 0.87 48 55890 7 0 7 0 56
ASE_00388 0.77 0.60 1.00 53 45700 1 0 0 1 36
ASE_00390 0.78 0.62 0.98 53 42141 1 0 1 0 32
ASE_00393 0.71 0.56 0.91 52 47838 5 0 5 0 41
ASE_00394 0.76 0.58 1.00 54 46917 0 0 0 0 39
ASE_00395 0.80 0.64 1.00 54 41562 0 0 0 0 30
ASE_00396 0.81 0.65 1.00 54 41562 0 0 0 0 29
ASE_00397 0.74 0.54 1.00 57 54558 0 0 0 0 48
ASE_00398 0.72 0.52 1.00 54 55891 0 0 0 0 50
ASE_00400 0.72 0.52 1.00 55 57915 1 0 0 1 51
ASE_00401 0.62 0.40 0.96 50 76976 2 1 1 0 76
ASE_00402 0.80 0.65 1.00 55 42431 0 0 0 0 30
ASE_00403 0.73 0.53 1.00 57 55888 0 0 0 0 50
ASE_00404 0.80 0.65 1.00 55 43016 1 0 0 1 30
ASE_00406 0.78 0.61 1.00 57 48771 0 0 0 0 37
ASE_00411 0.67 0.55 0.82 49 49395 11 5 6 0 40
ASE_00412 0.63 0.47 0.84 49 58253 9 2 7 0 56
ASE_00413 0.72 0.57 0.90 46 44500 7 2 3 2 35
ASE_00414 0.58 0.44 0.76 42 46305 13 3 10 0 53
ASE_00415 0.57 0.40 0.80 41 54895 10 0 10 0 62
ASE_00416 0.76 0.61 0.94 78 77338 5 1 4 0 49
ASE_00417 0.80 0.65 0.98 65 54549 1 0 1 0 35
ASE_00418 0.81 0.67 0.98 50 38730 1 0 1 0 25
ASE_00419 0.67 0.50 0.89 51 54889 6 2 4 0 52
ASE_00422 0.74 0.57 0.96 54 46915 3 0 2 1 40
ASE_00423 0.77 0.64 0.93 70 56878 6 0 5 1 39
ASE_00426 0.52 0.41 0.68 44 61010 22 5 16 1 64
ASE_00428 0.77 0.62 0.94 78 76553 5 1 4 0 47
ASE_00430 0.73 0.55 0.98 53 46917 1 0 1 0 44
ASE_00431 0.56 0.44 0.71 42 46301 17 7 10 0 53
ASE_00434 0.74 0.61 0.89 67 68190 14 0 8 6 43
ASE_00437 0.52 0.40 0.67 54 79320 27 0 27 0 81
ASE_00438 0.62 0.42 0.92 49 66013 4 1 3 0 67
ASE_00441 0.65 0.44 0.96 49 64210 3 0 2 1 63
ASE_00447 0.84 0.71 1.00 82 60296 0 0 0 0 34
ASE_00448 0.81 0.69 0.95 77 64180 4 0 4 0 35
ASE_00451 0.79 0.64 0.96 80 70793 3 0 3 0 45
CRW_00013 0.37 0.21 0.65 24 103703 17 1 12 4 91
CRW_00016 0.36 0.20 0.65 24 77384 16 1 12 3 96
CRW_00610 0.51 0.33 0.77 27 36280 11 1 7 3 54
CRW_00613 0.48 0.32 0.71 25 34945 14 0 10 4 53
CRW_00614 0.43 0.30 0.63 17 121744 16 2 8 6 40
CRW_00618 0.41 0.28 0.61 17 56252 12 3 8 1 44
CRW_00619 0.53 0.30 0.92 22 165001 5 0 2 3 51
CRW_00620 0.44 0.29 0.69 18 150949 18 0 8 10 45
CRW_00621 0.40 0.27 0.61 19 153150 14 3 9 2 52
CRW_00623 0.49 0.29 0.83 24 129766 9 1 4 4 59
CRW_00633 0.31 0.17 0.58 18 63515 14 2 11 1 88
CRW_00634 0.35 0.20 0.61 19 64589 20 1 11 8 75
CRW_00670 0.49 0.28 0.89 33 70088 8 0 4 4 87
CRW_00671 0.50 0.28 0.89 33 62798 8 0 4 4 84
CRW_00672 0.51 0.30 0.89 33 72353 8 0 4 4 78
CRW_00674 0.29 0.16 0.54 20 83399 20 6 11 3 104
CRW_00676 0.35 0.17 0.69 20 93499 20 0 9 11 95
CRW_00692 0.39 0.22 0.69 20 68606 20 0 9 11 70
PDB_00827 0.58 0.40 0.84 32 26990 6 1 5 0 49
PDB_00919 0.49 0.35 0.69 36 44201 18 0 16 2 67
RFA_00597 0.73 0.64 0.83 70 97819 19 0 14 5 39
RFA_00598 0.72 0.63 0.81 64 84587 26 0 15 11 37
RFA_00599 0.85 0.73 0.99 81 101393 4 0 1 3 30
RFA_00600 0.79 0.68 0.92 68 120221 15 0 6 9 32
RFA_00601 0.82 0.71 0.95 81 99150 9 0 4 5 33
RFA_00602 0.81 0.71 0.93 82 101387 10 0 6 4 34
TMR_00173 0.12 0.07 0.19 3 42179 23 0 13 10 39
TMR_00357 0.37 0.26 0.52 24 82982 24 7 15 2 68
TMR_00601 0.51 0.38 0.70 16 58973 33 2 5 26 26
TMR_00696 0.44 0.30 0.65 34 85026 19 2 16 1 80

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Performance of McQFold - scored lower in this pairwise comparison

1. Total counts & total scores for McQFold

Total Base Pair Counts
Total TP 13240
Total TN 17457424
Total FP 14834
Total FP CONTRA 1674
Total FP INCONS 11447
Total FP COMP 1713
Total FN 15637
Total Scores
MCC 0.479
Average MCC ± 95% Confidence Intervals 0.478 ± 0.018
Sensitivity 0.458
Positive Predictive Value 0.502
Nr of predictions 277

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2. Individual counts for McQFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00001 0.78 0.73 0.82 55 34124 17 7 5 5 20
ASE_00002 0.80 0.75 0.86 55 35447 12 4 5 3 18
ASE_00004 0.50 0.48 0.52 47 47805 48 9 34 5 50
ASE_00005 0.52 0.46 0.59 54 57878 40 0 38 2 63
ASE_00006 0.35 0.34 0.36 32 47498 60 6 50 4 61
ASE_00007 0.42 0.39 0.46 43 59591 55 2 49 4 67
ASE_00009 0.67 0.64 0.70 43 26045 18 3 15 0 24
ASE_00012 0.42 0.39 0.46 48 73816 61 3 53 5 75
ASE_00014 0.47 0.47 0.48 50 54180 56 9 46 1 56
ASE_00017 0.18 0.20 0.17 13 50963 78 25 39 14 51
ASE_00018 0.54 0.51 0.57 68 80482 52 2 49 1 66
ASE_00020 0.47 0.47 0.48 59 73797 64 9 55 0 67
ASE_00021 0.60 0.54 0.67 86 104068 47 2 40 5 74
ASE_00022 0.60 0.56 0.65 70 82920 45 5 33 7 54
ASE_00023 0.57 0.57 0.58 72 84131 57 6 46 5 55
ASE_00025 0.36 0.37 0.35 26 78531 92 6 43 43 45
ASE_00026 0.34 0.31 0.38 34 59595 58 7 49 2 76
ASE_00028 0.56 0.54 0.59 68 84550 50 11 37 2 58
ASE_00029 0.53 0.49 0.58 60 82924 48 3 41 4 62
ASE_00030 0.59 0.56 0.62 81 85360 51 6 44 1 64
ASE_00031 0.54 0.50 0.58 63 86627 56 5 41 10 63
ASE_00032 0.61 0.58 0.64 69 80093 39 12 26 1 49
ASE_00033 0.38 0.34 0.42 41 64883 57 3 53 1 80
ASE_00035 0.29 0.27 0.32 32 70401 71 9 58 4 86
ASE_00036 0.48 0.45 0.50 60 75736 64 8 51 5 72
ASE_00037 0.42 0.38 0.46 42 59248 50 5 45 0 68
ASE_00038 0.41 0.39 0.43 39 53538 53 3 48 2 62
ASE_00040 0.27 0.26 0.29 34 78886 88 9 74 5 99
ASE_00041 0.46 0.43 0.51 46 57539 48 6 39 3 62
ASE_00042 0.56 0.53 0.60 77 89972 53 4 47 2 68
ASE_00044 0.78 0.76 0.80 80 54515 25 4 16 5 25
ASE_00046 0.57 0.51 0.63 53 50319 32 3 28 1 50
ASE_00047 0.46 0.42 0.50 54 74198 54 3 50 1 76
ASE_00052 0.44 0.42 0.46 47 61323 59 9 46 4 65
ASE_00053 0.56 0.55 0.57 73 79274 62 9 45 8 60
ASE_00057 0.55 0.52 0.58 70 82095 57 13 37 7 64
ASE_00064 0.50 0.49 0.51 44 45364 46 5 38 3 45
ASE_00066 0.35 0.32 0.39 41 72286 64 3 60 1 89
ASE_00068 0.70 0.60 0.82 51 37613 16 2 9 5 34
ASE_00069 0.53 0.50 0.56 70 82902 60 6 50 4 70
ASE_00074 0.42 0.40 0.44 48 67786 62 3 59 0 71
ASE_00075 0.51 0.46 0.57 74 108681 62 4 52 6 88
ASE_00076 0.51 0.47 0.56 56 68165 46 2 42 2 62
ASE_00077 0.42 0.40 0.45 34 45075 47 5 36 6 52
ASE_00078 0.55 0.52 0.58 43 42997 38 2 29 7 40
ASE_00079 0.55 0.52 0.59 52 55523 39 5 31 3 48
ASE_00080 0.32 0.30 0.35 37 71524 71 6 64 1 86
ASE_00081 0.31 0.29 0.34 28 49688 56 5 49 2 69
ASE_00082 0.38 0.36 0.40 42 70396 73 2 60 11 74
ASE_00083 0.25 0.25 0.26 27 62379 75 6 69 0 83
ASE_00084 0.60 0.57 0.64 56 53540 36 2 30 4 43
ASE_00087 0.49 0.42 0.57 61 88303 52 2 44 6 83
ASE_00090 0.52 0.52 0.52 53 55510 52 6 42 4 48
ASE_00092 0.46 0.44 0.49 50 63444 55 6 46 3 63
ASE_00096 0.56 0.50 0.63 58 63454 35 2 32 1 57
ASE_00099 0.58 0.56 0.61 67 64510 44 4 39 1 53
ASE_00100 0.32 0.33 0.31 25 82134 111 7 49 55 51
ASE_00102 0.47 0.45 0.50 75 117705 78 5 70 3 91
ASE_00104 0.53 0.52 0.55 62 64148 52 8 43 1 57
ASE_00105 0.35 0.32 0.38 36 64165 64 2 58 4 75
ASE_00107 0.56 0.53 0.59 67 73039 48 1 46 1 60
ASE_00108 0.33 0.38 0.29 24 46888 72 19 40 13 39
ASE_00111 0.34 0.42 0.27 24 49998 74 33 31 10 33
ASE_00112 0.74 0.70 0.78 81 75362 33 2 21 10 35
ASE_00115 0.61 0.57 0.64 58 54525 40 4 28 8 43
ASE_00116 0.52 0.50 0.54 33 31565 32 3 25 4 33
ASE_00118 0.39 0.37 0.40 38 60632 60 3 53 4 64
ASE_00119 0.83 0.81 0.86 87 62734 14 2 12 0 21
ASE_00120 0.47 0.46 0.49 43 46883 45 4 41 0 51
ASE_00121 0.47 0.46 0.48 42 45063 47 7 38 2 50
ASE_00122 0.70 0.67 0.73 59 43284 25 1 21 3 29
ASE_00123 0.43 0.40 0.47 34 38430 45 0 39 6 51
ASE_00125 0.43 0.38 0.49 33 39272 38 2 33 3 55
ASE_00128 0.43 0.39 0.48 39 53219 47 3 40 4 61
ASE_00129 0.61 0.59 0.62 66 62729 42 3 37 2 45
ASE_00131 0.37 0.33 0.42 28 39274 43 3 35 5 57
ASE_00132 0.65 0.60 0.71 57 50323 24 4 19 1 38
ASE_00134 0.33 0.32 0.35 30 50317 57 7 49 1 65
ASE_00135 0.30 0.28 0.31 31 63090 74 3 66 5 78
ASE_00136 0.67 0.64 0.71 59 48122 32 1 23 8 33
ASE_00137 0.53 0.52 0.55 51 48423 45 5 37 3 47
ASE_00138 0.56 0.51 0.63 41 40405 25 4 20 1 40
ASE_00139 0.55 0.52 0.58 54 54192 42 1 38 3 50
ASE_00140 0.53 0.49 0.57 61 70769 47 7 39 1 64
ASE_00142 0.59 0.57 0.61 69 67048 47 5 39 3 53
ASE_00145 0.52 0.50 0.54 56 70022 50 2 45 3 55
ASE_00146 0.53 0.49 0.58 61 70770 48 1 44 3 63
ASE_00148 0.64 0.62 0.66 96 112430 49 4 45 0 58
ASE_00151 0.53 0.49 0.58 48 51920 39 9 26 4 50
ASE_00153 0.51 0.53 0.49 39 57550 72 9 32 31 34
ASE_00154 0.62 0.61 0.64 65 65239 37 1 36 0 42
ASE_00155 0.59 0.56 0.62 80 93398 54 3 47 4 62
ASE_00163 0.41 0.40 0.42 37 53213 57 4 47 6 56
ASE_00165 0.40 0.39 0.42 39 52882 56 6 48 2 62
ASE_00168 0.32 0.38 0.28 24 60640 89 18 44 27 40
ASE_00169 0.43 0.38 0.48 41 57205 47 2 43 2 66
ASE_00170 0.72 0.69 0.74 64 48742 24 2 20 2 29
ASE_00171 0.52 0.50 0.55 47 48431 38 3 35 0 47
ASE_00172 0.50 0.47 0.54 50 58903 50 5 38 7 56
ASE_00174 0.44 0.41 0.46 45 60978 53 5 47 1 64
ASE_00175 0.22 0.21 0.23 23 59931 80 5 72 3 84
ASE_00176 0.65 0.59 0.71 65 59940 30 4 22 4 45
ASE_00179 0.54 0.52 0.56 44 44174 36 8 27 1 40
ASE_00180 0.42 0.41 0.42 41 51263 60 4 52 4 59
ASE_00181 0.53 0.54 0.53 57 57522 51 4 47 0 49
ASE_00182 0.45 0.40 0.50 55 84145 57 2 53 2 81
ASE_00184 0.52 0.51 0.54 52 54519 46 8 36 2 50
ASE_00185 0.29 0.28 0.31 36 73419 81 14 67 0 92
ASE_00186 0.55 0.51 0.59 67 78889 56 3 44 9 65
ASE_00187 0.51 0.48 0.56 55 68536 48 3 41 4 60
ASE_00189 0.54 0.54 0.55 55 63090 47 7 38 2 47
ASE_00190 0.55 0.52 0.57 47 45369 40 2 33 5 43
ASE_00192 0.47 0.45 0.49 60 84543 68 10 53 5 73
ASE_00194 0.40 0.39 0.42 47 73423 67 15 51 1 72
ASE_00196 0.78 0.75 0.81 56 31557 16 2 11 3 19
ASE_00197 0.42 0.39 0.45 56 89129 76 1 67 8 89
ASE_00203 0.54 0.55 0.53 53 46565 51 4 43 4 43
ASE_00204 0.53 0.49 0.58 55 67801 46 7 33 6 57
ASE_00205 0.52 0.52 0.53 47 45967 45 10 32 3 43
ASE_00209 0.62 0.58 0.66 51 42994 26 4 22 0 37
ASE_00210 0.57 0.55 0.58 36 27199 28 6 20 2 29
ASE_00212 0.43 0.40 0.46 59 93832 80 3 67 10 89
ASE_00213 0.71 0.70 0.73 46 27198 18 4 13 1 20
ASE_00214 0.66 0.63 0.70 65 56187 35 2 26 7 38
ASE_00215 0.30 0.28 0.32 28 48429 60 7 52 1 71
ASE_00216 0.65 0.62 0.67 51 39264 26 7 18 1 31
ASE_00217 0.21 0.19 0.25 17 40401 54 6 46 2 73
ASE_00221 0.32 0.29 0.35 34 64522 65 3 61 1 83
ASE_00222 0.52 0.50 0.55 78 111958 65 5 60 0 79
ASE_00227 0.32 0.29 0.36 38 78898 67 3 64 0 95
ASE_00228 0.38 0.37 0.40 32 46890 50 11 38 1 54
ASE_00229 0.52 0.53 0.52 46 42398 44 6 36 2 41
ASE_00231 0.63 0.60 0.67 58 47808 33 4 25 4 38
ASE_00232 0.70 0.70 0.69 59 38418 29 8 18 3 25
ASE_00234 0.31 0.28 0.34 36 75360 71 9 61 1 93
ASE_00237 0.11 0.13 0.09 7 45676 81 21 49 11 49
ASE_00238 0.47 0.44 0.51 50 64163 50 2 46 2 64
ASE_00240 0.26 0.26 0.27 24 46575 68 3 63 2 69
ASE_00241 0.20 0.18 0.23 16 43886 55 3 51 1 71
ASE_00242 0.63 0.59 0.67 66 60976 34 3 30 1 46
ASE_00246 0.29 0.28 0.30 19 48141 65 6 39 20 48
ASE_00247 0.60 0.63 0.57 40 54215 63 11 19 33 24
ASE_00248 0.19 0.18 0.20 20 62382 81 6 73 2 94
ASE_00250 0.61 0.57 0.64 75 78886 49 2 40 7 56
ASE_00252 0.48 0.45 0.51 76 115292 77 4 68 5 92
ASE_00254 0.38 0.37 0.40 30 36781 48 3 42 3 52
ASE_00255 0.55 0.53 0.58 69 74572 54 4 46 4 61
ASE_00257 0.50 0.48 0.53 47 50951 49 3 39 7 50
ASE_00263 0.62 0.59 0.65 71 70390 40 4 35 1 49
ASE_00264 0.43 0.43 0.44 43 49043 59 4 51 4 57
ASE_00267 0.21 0.19 0.23 17 45075 63 8 50 5 71
ASE_00270 0.45 0.42 0.49 54 72279 57 5 52 0 74
ASE_00274 0.49 0.44 0.55 45 55529 38 5 32 1 58
ASE_00277 0.39 0.37 0.40 34 48121 50 17 33 0 57
ASE_00279 0.16 0.15 0.17 15 53215 73 2 69 2 86
ASE_00280 0.40 0.40 0.41 39 51908 60 9 47 4 59
ASE_00281 0.74 0.66 0.84 58 44482 17 0 11 6 30
ASE_00282 0.55 0.50 0.60 64 77708 50 7 36 7 63
ASE_00283 0.54 0.52 0.55 56 61675 47 3 42 2 51
ASE_00284 0.21 0.20 0.22 22 58211 82 8 70 4 86
ASE_00285 0.54 0.52 0.57 63 68895 53 2 46 5 59
ASE_00286 0.38 0.35 0.42 32 46589 45 4 40 1 60
ASE_00287 0.28 0.27 0.30 28 54852 67 9 57 1 75
ASE_00288 0.68 0.60 0.78 56 45984 22 0 16 6 37
ASE_00289 0.71 0.65 0.78 102 100895 33 3 25 5 55
ASE_00292 0.42 0.38 0.48 52 81701 58 3 54 1 86
ASE_00294 0.43 0.41 0.45 70 114326 87 5 80 2 101
ASE_00295 0.46 0.41 0.52 54 73816 53 6 44 3 77
ASE_00296 0.15 0.14 0.17 21 91680 105 6 99 0 124
ASE_00297 0.34 0.33 0.36 32 52887 59 8 48 3 66
ASE_00298 0.21 0.21 0.22 24 67418 87 14 72 1 89
ASE_00299 0.48 0.45 0.51 45 49366 50 7 37 6 55
ASE_00313 0.60 0.57 0.62 51 62399 57 4 27 26 38
ASE_00316 0.45 0.48 0.42 47 107767 88 16 50 22 51
ASE_00318 0.64 0.62 0.66 73 80090 41 10 27 4 45
ASE_00327 0.78 0.75 0.82 67 57209 33 3 12 18 22
ASE_00328 0.61 0.60 0.63 67 72665 47 2 37 8 45
ASE_00330 0.64 0.67 0.63 60 56184 52 10 26 16 30
ASE_00332 0.41 0.40 0.43 55 81683 75 3 69 3 83
ASE_00335 0.62 0.58 0.68 67 75367 37 5 27 5 49
ASE_00337 0.54 0.56 0.52 40 39263 49 5 32 12 31
ASE_00338 0.44 0.43 0.45 42 66336 67 6 46 15 56
ASE_00339 0.50 0.50 0.51 59 80085 64 7 49 8 60
ASE_00340 0.34 0.35 0.33 30 45965 64 10 51 3 55
ASE_00342 0.68 0.63 0.73 73 62381 29 2 25 2 42
ASE_00343 0.69 0.69 0.69 78 83323 53 7 28 18 35
ASE_00346 0.38 0.36 0.41 35 48120 53 4 46 3 62
ASE_00353 0.61 0.60 0.62 64 57867 40 2 37 1 43
ASE_00359 0.11 0.10 0.12 8 42711 62 2 57 3 72
ASE_00360 0.40 0.37 0.44 24 29348 31 3 28 0 41
ASE_00361 0.43 0.40 0.47 51 75358 59 8 49 2 76
ASE_00362 0.53 0.53 0.53 48 48114 45 4 39 2 43
ASE_00363 0.49 0.48 0.51 45 51272 50 5 38 7 49
ASE_00364 0.55 0.51 0.59 54 54193 39 3 35 1 51
ASE_00366 0.40 0.40 0.40 39 58555 60 10 49 1 59
ASE_00367 0.44 0.43 0.45 37 42988 54 2 44 8 49
ASE_00369 0.57 0.55 0.60 59 55846 42 6 34 2 48
ASE_00370 0.43 0.40 0.47 34 41832 40 6 33 1 50
ASE_00372 0.56 0.55 0.58 55 51908 43 7 33 3 45
ASE_00374 0.56 0.56 0.56 49 44762 39 6 33 0 39
ASE_00375 0.56 0.51 0.61 56 60286 41 2 34 5 54
ASE_00376 0.55 0.51 0.60 54 56863 37 4 32 1 51
ASE_00377 0.76 0.71 0.81 76 57536 23 2 16 5 31
ASE_00379 0.46 0.44 0.49 39 45976 42 7 34 1 50
ASE_00380 0.44 0.41 0.46 41 54857 51 1 47 3 58
ASE_00382 0.73 0.68 0.78 57 41832 18 5 11 2 27
ASE_00383 0.39 0.36 0.43 38 54526 51 3 48 0 67
ASE_00384 0.32 0.30 0.35 28 48435 62 3 50 9 64
ASE_00385 0.58 0.56 0.61 45 41831 31 10 19 2 36
ASE_00386 0.58 0.56 0.60 54 50313 38 7 29 2 42
ASE_00387 0.49 0.48 0.50 50 55845 53 5 45 3 54
ASE_00388 0.51 0.49 0.54 44 45671 48 1 37 10 45
ASE_00390 0.53 0.51 0.55 43 42117 46 1 34 11 42
ASE_00393 0.37 0.34 0.41 32 47816 53 2 45 6 61
ASE_00394 0.57 0.55 0.59 51 46884 41 2 34 5 42
ASE_00395 0.71 0.67 0.76 56 41542 28 1 17 10 28
ASE_00396 0.47 0.46 0.48 38 41536 46 8 34 4 45
ASE_00397 0.51 0.47 0.55 49 54526 41 4 36 1 56
ASE_00398 0.39 0.38 0.40 39 55847 61 6 53 2 65
ASE_00400 0.54 0.53 0.54 56 57867 48 7 40 1 50
ASE_00401 0.54 0.52 0.56 65 76912 53 7 44 2 61
ASE_00402 0.59 0.55 0.64 47 42412 29 7 20 2 38
ASE_00403 0.24 0.22 0.27 24 55855 70 4 62 4 83
ASE_00404 0.17 0.16 0.18 14 42992 70 4 61 5 71
ASE_00406 0.56 0.54 0.57 51 48739 49 2 36 11 43
ASE_00411 0.27 0.27 0.27 24 49367 65 7 57 1 65
ASE_00412 0.26 0.25 0.27 26 58215 71 9 61 1 79
ASE_00413 0.48 0.48 0.49 39 44471 45 1 40 4 42
ASE_00414 0.24 0.23 0.26 22 46276 65 0 62 3 73
ASE_00415 0.62 0.59 0.65 61 54852 38 5 28 5 42
ASE_00416 0.52 0.50 0.54 63 77304 57 5 49 3 64
ASE_00417 0.36 0.37 0.36 37 54512 68 9 57 2 63
ASE_00418 0.12 0.12 0.12 9 38703 71 10 59 2 66
ASE_00419 0.75 0.71 0.78 73 54853 22 2 18 2 30
ASE_00422 0.63 0.61 0.65 57 46883 38 3 28 7 37
ASE_00423 0.36 0.35 0.38 38 56853 62 6 56 0 71
ASE_00426 0.50 0.51 0.50 55 60965 55 10 45 0 53
ASE_00428 0.54 0.51 0.57 64 76523 52 6 43 3 61
ASE_00430 0.64 0.62 0.67 60 46881 36 1 29 6 37
ASE_00431 0.58 0.52 0.64 49 46284 34 1 26 7 46
ASE_00434 0.78 0.71 0.85 78 68173 28 1 13 14 32
ASE_00437 0.45 0.42 0.48 57 79283 62 1 60 1 78
ASE_00438 0.42 0.39 0.46 45 65968 53 1 52 0 71
ASE_00441 0.73 0.65 0.81 73 64171 21 6 11 4 39
ASE_00447 0.70 0.65 0.75 75 60278 31 4 21 6 41
ASE_00448 0.37 0.34 0.40 38 64167 62 5 51 6 74
ASE_00451 0.37 0.35 0.40 44 70766 67 2 64 1 81
CRW_00013 0.10 0.10 0.11 11 103641 107 9 79 19 104
CRW_00016 0.66 0.61 0.72 73 77320 38 5 23 10 47
CRW_00610 0.50 0.48 0.51 39 36239 38 6 31 1 42
CRW_00613 0.81 0.73 0.89 57 34916 15 0 7 8 21
CRW_00614 0.07 0.09 0.06 5 121689 132 26 51 55 52
CRW_00618 0.37 0.39 0.34 24 56210 60 15 31 14 37
CRW_00619 0.00 0.00 0.00 0 164963 138 7 55 76 73
CRW_00620 0.19 0.21 0.18 13 150901 128 14 47 67 50
CRW_00621 0.28 0.25 0.30 18 153121 121 12 30 79 53
CRW_00623 0.12 0.13 0.11 11 129696 122 21 67 34 72
CRW_00633 0.74 0.72 0.77 76 63447 26 8 15 3 30
CRW_00634 0.44 0.41 0.47 39 64537 48 18 26 4 55
CRW_00670 0.54 0.53 0.55 63 70011 53 6 45 2 57
CRW_00671 0.66 0.59 0.74 69 62742 28 5 19 4 48
CRW_00672 0.52 0.50 0.56 55 72291 48 9 35 4 56
CRW_00674 0.43 0.42 0.44 52 83319 69 14 51 4 72
CRW_00676 0.30 0.30 0.31 35 93414 85 9 70 6 80
CRW_00692 0.26 0.27 0.25 24 68538 77 23 50 4 66
PDB_00827 0.68 0.59 0.79 48 26967 15 0 13 2 33
PDB_00919 0.53 0.49 0.59 50 44168 38 3 32 3 53
RFA_00597 0.34 0.37 0.31 40 97776 101 20 67 14 69
RFA_00598 0.35 0.36 0.35 36 84563 76 12 55 9 65
RFA_00599 0.39 0.40 0.38 44 101359 92 13 59 20 67
RFA_00600 0.18 0.21 0.16 21 120164 129 29 81 19 79
RFA_00601 0.09 0.10 0.08 11 99104 129 18 102 9 103
RFA_00602 0.41 0.44 0.39 51 101343 91 19 62 10 65
TMR_00173 0.34 0.40 0.29 17 42137 64 19 22 23 25
TMR_00357 0.57 0.62 0.53 57 82921 57 23 27 7 35
TMR_00601 0.79 0.71 0.88 30 58962 47 1 3 43 12
TMR_00696 0.47 0.44 0.50 50 84978 63 10 40 13 64

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.