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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

  4. Performance of PknotsRG - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(seed) & PknotsRG [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(seed) PknotsRG
MCC 0.691 > 0.527
Average MCC ± 95% Confidence Intervals 0.688 ± 0.015 > 0.520 ± 0.019
Sensitivity 0.521 > 0.517
Positive Predictive Value 0.919 > 0.539
Total TP 15031 > 14931
Total TN 17467425 > 17456106
Total FP 1662 < 14721
Total FP CONTRA 179 < 1770
Total FP INCONS 1150 < 10978
Total FP COMP 333 < 1973
Total FN 13846 < 13946
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of CentroidAlifold(seed) and PknotsRG. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(seed) and PknotsRG).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for CentroidAlifold(seed) and PknotsRG).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(seed) and PknotsRG. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(seed) and PknotsRG).

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Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(seed)

Total Base Pair Counts
Total TP 15031
Total TN 17467425
Total FP 1662
Total FP CONTRA 179
Total FP INCONS 1150
Total FP COMP 333
Total FN 13846
Total Scores
MCC 0.691
Average MCC ± 95% Confidence Intervals 0.688 ± 0.015
Sensitivity 0.521
Positive Predictive Value 0.919
Nr of predictions 277

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2. Individual counts for CentroidAlifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00001 0.81 0.65 1.00 49 34142 0 0 0 0 26
ASE_00002 0.82 0.67 1.00 49 35462 0 0 0 0 24
ASE_00004 0.61 0.45 0.83 44 47842 9 0 9 0 53
ASE_00005 0.75 0.57 0.97 67 57901 2 0 2 0 50
ASE_00006 0.58 0.44 0.76 41 47532 13 0 13 0 52
ASE_00007 0.83 0.71 0.98 78 59605 2 0 2 0 32
ASE_00009 0.79 0.67 0.94 45 26058 3 0 3 0 22
ASE_00012 0.75 0.59 0.95 73 73843 7 1 3 3 50
ASE_00014 0.74 0.58 0.95 61 54221 3 0 3 0 45
ASE_00017 0.79 0.69 0.90 44 50991 5 1 4 0 20
ASE_00018 0.78 0.60 1.00 81 80520 0 0 0 0 53
ASE_00020 0.63 0.43 0.93 54 73862 4 3 1 0 72
ASE_00021 0.63 0.44 0.90 71 104117 11 2 6 3 89
ASE_00022 0.80 0.65 1.00 80 82948 5 0 0 5 44
ASE_00023 0.47 0.35 0.63 45 84184 28 8 18 2 82
ASE_00025 0.69 0.58 0.84 41 78557 8 1 7 0 30
ASE_00026 0.80 0.67 0.96 74 59608 4 0 3 1 36
ASE_00028 0.80 0.64 1.00 81 84585 3 0 0 3 45
ASE_00029 0.45 0.34 0.61 41 82961 30 4 22 4 81
ASE_00030 0.66 0.49 0.90 71 85412 8 0 8 0 74
ASE_00031 0.51 0.37 0.72 46 86672 18 0 18 0 80
ASE_00032 0.38 0.27 0.54 32 80141 30 1 26 3 86
ASE_00033 0.80 0.65 0.99 79 64900 3 1 0 2 42
ASE_00035 0.77 0.64 0.94 75 70420 8 0 5 3 43
ASE_00036 0.75 0.58 0.99 76 75778 1 1 0 0 56
ASE_00037 0.84 0.71 1.00 78 59262 1 0 0 1 32
ASE_00038 0.74 0.54 1.00 55 53573 0 0 0 0 46
ASE_00040 0.77 0.59 1.00 79 78924 2 0 0 2 54
ASE_00041 0.77 0.64 0.92 69 57555 6 0 6 0 39
ASE_00042 0.65 0.49 0.87 71 90018 11 0 11 0 74
ASE_00044 0.83 0.70 1.00 73 54542 0 0 0 0 32
ASE_00046 0.73 0.62 0.86 64 50329 10 0 10 0 39
ASE_00047 0.70 0.52 0.93 68 74232 5 0 5 0 62
ASE_00052 0.75 0.63 0.91 70 61348 8 0 7 1 42
ASE_00053 0.71 0.54 0.92 72 79323 6 3 3 0 61
ASE_00057 0.73 0.57 0.93 77 82132 6 2 4 0 57
ASE_00064 0.77 0.60 1.00 53 45398 0 0 0 0 36
ASE_00066 0.75 0.56 1.00 73 72317 1 0 0 1 57
ASE_00068 0.54 0.38 0.78 32 37634 9 0 9 0 53
ASE_00069 0.75 0.57 0.98 80 82946 3 0 2 1 60
ASE_00074 0.83 0.69 1.00 82 67814 1 0 0 1 37
ASE_00075 0.64 0.44 0.92 71 108734 11 1 5 5 91
ASE_00076 0.69 0.48 1.00 57 68208 0 0 0 0 61
ASE_00077 0.79 0.64 0.96 55 45093 2 1 1 0 31
ASE_00078 0.83 0.69 1.00 57 43014 0 0 0 0 26
ASE_00079 0.63 0.47 0.84 47 55555 9 0 9 0 53
ASE_00080 0.45 0.30 0.66 37 71575 19 1 18 0 86
ASE_00081 0.77 0.59 1.00 57 49713 0 0 0 0 40
ASE_00082 0.66 0.43 1.00 50 70450 6 0 0 6 66
ASE_00083 0.72 0.52 1.00 57 62424 0 0 0 0 53
ASE_00084 0.75 0.57 0.98 56 53571 1 1 0 0 43
ASE_00087 0.60 0.38 0.95 54 88353 3 0 3 0 90
ASE_00090 0.75 0.56 1.00 57 55554 0 0 0 0 44
ASE_00092 0.70 0.50 0.98 56 63489 1 1 0 0 57
ASE_00096 0.63 0.44 0.89 51 63489 6 0 6 0 64
ASE_00099 0.82 0.67 1.00 80 64540 0 0 0 0 40
ASE_00100 0.72 0.58 0.90 44 82166 5 1 4 0 32
ASE_00102 0.57 0.40 0.81 66 117774 15 1 14 0 100
ASE_00104 0.81 0.67 0.99 80 64180 1 0 1 0 39
ASE_00105 0.55 0.40 0.76 44 64203 14 4 10 0 67
ASE_00107 0.78 0.63 0.96 80 73070 3 0 3 0 47
ASE_00108 0.79 0.70 0.90 44 46922 5 1 4 0 19
ASE_00111 0.83 0.74 0.93 42 50041 3 1 2 0 15
ASE_00112 0.50 0.34 0.71 40 75410 16 0 16 0 76
ASE_00115 0.74 0.54 1.00 55 54560 0 0 0 0 46
ASE_00116 0.86 0.76 0.98 50 31575 1 0 1 0 16
ASE_00118 0.68 0.49 0.94 50 60673 4 1 2 1 52
ASE_00119 0.66 0.44 0.98 48 62786 1 1 0 0 60
ASE_00120 0.79 0.64 0.98 60 46910 2 0 1 1 34
ASE_00121 0.81 0.66 0.98 61 45088 1 0 1 0 31
ASE_00122 0.80 0.64 1.00 56 43309 1 0 0 1 32
ASE_00123 0.68 0.48 0.95 41 38460 2 0 2 0 44
ASE_00125 0.67 0.47 0.95 41 39297 2 0 2 0 47
ASE_00128 0.73 0.54 1.00 54 53247 0 0 0 0 46
ASE_00129 0.71 0.50 1.00 56 62779 0 0 0 0 55
ASE_00131 0.65 0.44 0.97 37 39302 1 1 0 0 48
ASE_00132 0.76 0.59 0.98 56 50346 1 1 0 0 39
ASE_00134 0.69 0.54 0.89 51 50346 6 0 6 0 44
ASE_00135 0.53 0.39 0.74 42 63133 15 0 15 0 67
ASE_00136 0.75 0.59 0.95 54 48148 3 0 3 0 38
ASE_00137 0.70 0.53 0.93 52 48460 4 0 4 0 46
ASE_00138 0.79 0.63 1.00 51 40419 0 0 0 0 30
ASE_00139 0.73 0.54 1.00 56 54229 0 0 0 0 48
ASE_00140 0.64 0.43 0.95 54 70819 3 3 0 0 71
ASE_00142 0.77 0.61 0.97 75 67084 4 0 2 2 47
ASE_00145 0.77 0.59 1.00 66 70059 0 0 0 0 45
ASE_00146 0.78 0.62 0.97 77 70797 2 0 2 0 47
ASE_00148 0.62 0.41 0.95 63 112509 3 0 3 0 91
ASE_00151 0.80 0.70 0.92 69 51928 6 5 1 0 29
ASE_00153 0.67 0.53 0.85 39 57584 7 1 6 0 34
ASE_00154 0.75 0.59 0.95 63 65275 3 0 3 0 44
ASE_00155 0.68 0.46 1.00 66 93462 0 0 0 0 76
ASE_00163 0.77 0.59 1.00 55 53246 0 0 0 0 38
ASE_00165 0.69 0.50 0.94 51 52921 4 1 2 1 50
ASE_00168 0.79 0.69 0.90 44 60677 5 1 4 0 20
ASE_00169 0.65 0.48 0.88 51 57233 7 1 6 0 56
ASE_00170 0.78 0.60 1.00 56 48772 0 0 0 0 37
ASE_00171 0.76 0.59 1.00 55 48461 1 0 0 1 39
ASE_00172 0.72 0.53 0.98 56 58939 1 1 0 0 50
ASE_00174 0.60 0.43 0.82 47 61018 10 1 9 0 62
ASE_00175 0.71 0.51 0.98 55 59975 1 1 0 0 52
ASE_00176 0.71 0.50 1.00 55 59976 0 0 0 0 55
ASE_00179 0.79 0.63 0.98 53 44199 2 0 1 1 31
ASE_00180 0.73 0.54 0.98 54 51305 1 1 0 0 46
ASE_00181 0.71 0.52 0.96 55 57573 3 2 0 1 51
ASE_00182 0.61 0.40 0.95 54 84198 3 0 3 0 82
ASE_00184 0.75 0.56 1.00 57 54558 0 0 0 0 45
ASE_00185 0.64 0.41 0.98 53 73482 1 1 0 0 75
ASE_00186 0.66 0.51 0.86 67 78925 14 0 11 3 65
ASE_00187 0.69 0.51 0.92 59 68571 5 1 4 0 56
ASE_00189 0.76 0.62 0.94 63 63123 8 0 4 4 39
ASE_00190 0.74 0.54 1.00 49 45402 3 0 0 3 41
ASE_00192 0.51 0.35 0.75 47 84603 20 0 16 4 86
ASE_00194 0.72 0.53 0.97 63 73471 7 0 2 5 56
ASE_00196 0.82 0.69 0.96 52 31572 2 0 2 0 23
ASE_00197 0.63 0.46 0.86 67 89175 12 0 11 1 78
ASE_00203 0.72 0.55 0.93 53 46608 4 2 2 0 43
ASE_00204 0.73 0.55 0.97 62 67832 7 1 1 5 50
ASE_00205 0.82 0.67 1.00 60 45996 1 0 0 1 30
ASE_00209 0.83 0.69 0.98 61 43009 1 0 1 0 27
ASE_00210 0.74 0.65 0.86 42 27212 9 0 7 2 23
ASE_00212 0.63 0.45 0.89 66 93887 9 0 8 1 82
ASE_00213 0.83 0.71 0.98 47 27213 3 0 1 2 19
ASE_00214 0.73 0.54 0.98 56 56223 2 1 0 1 47
ASE_00215 0.51 0.32 0.82 32 48477 7 0 7 0 67
ASE_00216 0.81 0.66 1.00 54 39286 0 0 0 0 28
ASE_00217 0.82 0.67 1.00 60 40410 1 0 0 1 30
ASE_00221 0.83 0.70 0.99 82 64537 1 0 1 0 35
ASE_00222 0.65 0.42 1.00 66 112035 0 0 0 0 91
ASE_00227 0.57 0.43 0.76 57 78928 18 0 18 0 76
ASE_00228 0.72 0.57 0.91 49 46917 6 3 2 1 37
ASE_00229 0.78 0.61 1.00 53 42433 2 0 0 2 34
ASE_00231 0.59 0.45 0.78 43 47840 12 0 12 0 53
ASE_00232 0.81 0.65 1.00 55 38448 0 0 0 0 29
ASE_00234 0.64 0.43 0.95 55 75408 3 3 0 0 74
ASE_00237 0.83 0.73 0.93 41 45709 3 1 2 0 15
ASE_00238 0.61 0.44 0.86 50 64203 8 2 6 0 64
ASE_00240 0.62 0.48 0.79 45 46608 12 0 12 0 48
ASE_00241 0.79 0.64 0.98 56 43899 1 0 1 0 31
ASE_00242 0.85 0.72 1.00 81 60994 1 0 0 1 31
ASE_00246 0.79 0.67 0.92 45 48156 4 1 3 0 22
ASE_00247 0.79 0.69 0.90 44 54236 5 1 4 0 20
ASE_00248 0.84 0.71 1.00 81 62400 1 0 0 1 33
ASE_00250 0.72 0.56 0.91 74 78922 8 1 6 1 57
ASE_00252 0.63 0.43 0.92 72 115362 10 2 4 4 96
ASE_00254 0.81 0.66 1.00 54 36802 0 0 0 0 28
ASE_00255 0.64 0.51 0.80 66 74609 16 0 16 0 64
ASE_00257 0.68 0.52 0.91 50 50985 5 1 4 0 47
ASE_00263 0.68 0.47 0.98 56 70443 1 1 0 0 64
ASE_00264 0.58 0.40 0.85 40 49094 8 0 7 1 60
ASE_00267 0.80 0.64 1.00 56 45094 0 0 0 0 32
ASE_00270 0.55 0.34 0.90 43 72342 6 0 5 1 85
ASE_00274 0.71 0.53 0.95 55 55553 3 3 0 0 48
ASE_00277 0.73 0.57 0.93 52 48149 4 3 1 0 39
ASE_00279 0.73 0.54 0.98 55 53245 1 0 1 0 46
ASE_00280 0.74 0.57 0.97 56 51945 2 1 1 0 42
ASE_00281 0.78 0.63 0.98 55 44495 1 0 1 0 33
ASE_00282 0.66 0.45 0.98 57 77757 1 1 0 0 70
ASE_00283 0.72 0.52 0.98 56 61719 1 0 1 0 51
ASE_00284 0.72 0.53 0.98 57 58253 1 1 0 0 51
ASE_00285 0.68 0.47 1.00 57 68949 0 0 0 0 65
ASE_00286 0.78 0.61 1.00 56 46609 0 0 0 0 36
ASE_00287 0.67 0.50 0.89 51 54889 6 0 6 0 52
ASE_00288 0.75 0.58 0.96 54 46000 2 2 0 0 39
ASE_00289 0.66 0.46 0.95 73 100948 4 0 4 0 84
ASE_00292 0.76 0.58 1.00 80 81730 1 0 0 1 58
ASE_00294 0.68 0.47 0.98 81 114398 2 0 2 0 90
ASE_00295 0.77 0.59 1.00 77 73843 0 0 0 0 54
ASE_00296 0.73 0.54 0.98 79 91725 3 0 2 1 66
ASE_00297 0.61 0.45 0.83 44 52922 9 2 7 0 54
ASE_00298 0.70 0.50 0.98 56 67471 1 1 0 0 57
ASE_00299 0.55 0.44 0.70 44 49392 19 0 19 0 56
ASE_00313 0.50 0.34 0.75 30 62441 14 2 8 4 59
ASE_00316 0.46 0.27 0.79 26 107847 8 0 7 1 72
ASE_00318 0.79 0.62 1.00 73 80127 6 0 0 6 45
ASE_00327 0.61 0.43 0.86 38 57247 11 0 6 5 51
ASE_00328 0.83 0.70 1.00 78 72693 5 0 0 5 34
ASE_00330 0.66 0.48 0.91 43 56233 5 0 4 1 47
ASE_00332 0.78 0.60 1.00 83 81727 0 0 0 0 55
ASE_00335 0.81 0.66 1.00 77 75389 7 0 0 7 39
ASE_00337 0.57 0.44 0.76 31 39299 18 0 10 8 40
ASE_00338 0.51 0.33 0.80 32 66390 8 0 8 0 66
ASE_00339 0.58 0.46 0.72 55 80124 22 7 14 1 64
ASE_00340 0.73 0.56 0.94 48 46005 7 0 3 4 37
ASE_00342 0.84 0.71 1.00 82 62399 0 0 0 0 33
ASE_00343 0.37 0.27 0.51 31 83375 32 2 28 2 82
ASE_00346 0.61 0.49 0.75 48 48141 16 0 16 0 49
ASE_00353 0.72 0.52 0.98 56 57913 2 1 0 1 51
ASE_00359 0.77 0.61 0.98 49 42728 2 0 1 1 31
ASE_00360 0.87 0.77 0.98 50 29352 1 0 1 0 15
ASE_00361 0.65 0.43 0.98 55 75410 1 1 0 0 72
ASE_00362 0.78 0.62 1.00 56 48149 1 0 0 1 35
ASE_00363 0.70 0.54 0.89 51 51303 6 0 6 0 43
ASE_00364 0.66 0.49 0.89 51 54228 6 1 5 0 54
ASE_00366 0.69 0.53 0.90 52 58595 6 2 4 0 46
ASE_00367 0.81 0.65 1.00 56 43015 1 0 0 1 30
ASE_00369 0.73 0.53 1.00 57 55888 0 0 0 0 50
ASE_00370 0.78 0.62 0.98 52 41852 1 0 1 0 32
ASE_00372 0.73 0.54 0.98 54 51948 1 0 1 0 46
ASE_00374 0.78 0.60 1.00 53 44797 0 0 0 0 35
ASE_00375 0.71 0.51 1.00 56 60322 1 0 0 1 54
ASE_00376 0.68 0.50 0.93 53 56896 4 0 4 0 52
ASE_00377 0.67 0.50 0.91 53 57572 5 1 4 0 54
ASE_00379 0.79 0.63 1.00 56 46000 1 0 0 1 33
ASE_00380 0.75 0.57 1.00 56 54890 0 0 0 0 43
ASE_00382 0.80 0.64 1.00 54 41851 1 0 0 1 30
ASE_00383 0.74 0.54 1.00 57 54558 0 0 0 0 48
ASE_00384 0.78 0.61 1.00 56 48460 0 0 0 0 36
ASE_00385 0.71 0.56 0.90 45 41855 5 0 5 0 36
ASE_00386 0.77 0.59 1.00 57 50346 0 0 0 0 39
ASE_00387 0.63 0.46 0.87 48 55890 7 0 7 0 56
ASE_00388 0.77 0.60 1.00 53 45700 1 0 0 1 36
ASE_00390 0.78 0.62 0.98 53 42141 1 0 1 0 32
ASE_00393 0.71 0.56 0.91 52 47838 5 0 5 0 41
ASE_00394 0.76 0.58 1.00 54 46917 0 0 0 0 39
ASE_00395 0.80 0.64 1.00 54 41562 0 0 0 0 30
ASE_00396 0.81 0.65 1.00 54 41562 0 0 0 0 29
ASE_00397 0.74 0.54 1.00 57 54558 0 0 0 0 48
ASE_00398 0.72 0.52 1.00 54 55891 0 0 0 0 50
ASE_00400 0.72 0.52 1.00 55 57915 1 0 0 1 51
ASE_00401 0.62 0.40 0.96 50 76976 2 1 1 0 76
ASE_00402 0.80 0.65 1.00 55 42431 0 0 0 0 30
ASE_00403 0.73 0.53 1.00 57 55888 0 0 0 0 50
ASE_00404 0.80 0.65 1.00 55 43016 1 0 0 1 30
ASE_00406 0.78 0.61 1.00 57 48771 0 0 0 0 37
ASE_00411 0.67 0.55 0.82 49 49395 11 5 6 0 40
ASE_00412 0.63 0.47 0.84 49 58253 9 2 7 0 56
ASE_00413 0.72 0.57 0.90 46 44500 7 2 3 2 35
ASE_00414 0.58 0.44 0.76 42 46305 13 3 10 0 53
ASE_00415 0.57 0.40 0.80 41 54895 10 0 10 0 62
ASE_00416 0.76 0.61 0.94 78 77338 5 1 4 0 49
ASE_00417 0.80 0.65 0.98 65 54549 1 0 1 0 35
ASE_00418 0.81 0.67 0.98 50 38730 1 0 1 0 25
ASE_00419 0.67 0.50 0.89 51 54889 6 2 4 0 52
ASE_00422 0.74 0.57 0.96 54 46915 3 0 2 1 40
ASE_00423 0.77 0.64 0.93 70 56878 6 0 5 1 39
ASE_00426 0.52 0.41 0.68 44 61010 22 5 16 1 64
ASE_00428 0.77 0.62 0.94 78 76553 5 1 4 0 47
ASE_00430 0.73 0.55 0.98 53 46917 1 0 1 0 44
ASE_00431 0.56 0.44 0.71 42 46301 17 7 10 0 53
ASE_00434 0.74 0.61 0.89 67 68190 14 0 8 6 43
ASE_00437 0.52 0.40 0.67 54 79320 27 0 27 0 81
ASE_00438 0.62 0.42 0.92 49 66013 4 1 3 0 67
ASE_00441 0.65 0.44 0.96 49 64210 3 0 2 1 63
ASE_00447 0.84 0.71 1.00 82 60296 0 0 0 0 34
ASE_00448 0.81 0.69 0.95 77 64180 4 0 4 0 35
ASE_00451 0.79 0.64 0.96 80 70793 3 0 3 0 45
CRW_00013 0.37 0.21 0.65 24 103703 17 1 12 4 91
CRW_00016 0.36 0.20 0.65 24 77384 16 1 12 3 96
CRW_00610 0.51 0.33 0.77 27 36280 11 1 7 3 54
CRW_00613 0.48 0.32 0.71 25 34945 14 0 10 4 53
CRW_00614 0.43 0.30 0.63 17 121744 16 2 8 6 40
CRW_00618 0.41 0.28 0.61 17 56252 12 3 8 1 44
CRW_00619 0.53 0.30 0.92 22 165001 5 0 2 3 51
CRW_00620 0.44 0.29 0.69 18 150949 18 0 8 10 45
CRW_00621 0.40 0.27 0.61 19 153150 14 3 9 2 52
CRW_00623 0.49 0.29 0.83 24 129766 9 1 4 4 59
CRW_00633 0.31 0.17 0.58 18 63515 14 2 11 1 88
CRW_00634 0.35 0.20 0.61 19 64589 20 1 11 8 75
CRW_00670 0.49 0.28 0.89 33 70088 8 0 4 4 87
CRW_00671 0.50 0.28 0.89 33 62798 8 0 4 4 84
CRW_00672 0.51 0.30 0.89 33 72353 8 0 4 4 78
CRW_00674 0.29 0.16 0.54 20 83399 20 6 11 3 104
CRW_00676 0.35 0.17 0.69 20 93499 20 0 9 11 95
CRW_00692 0.39 0.22 0.69 20 68606 20 0 9 11 70
PDB_00827 0.58 0.40 0.84 32 26990 6 1 5 0 49
PDB_00919 0.49 0.35 0.69 36 44201 18 0 16 2 67
RFA_00597 0.73 0.64 0.83 70 97819 19 0 14 5 39
RFA_00598 0.72 0.63 0.81 64 84587 26 0 15 11 37
RFA_00599 0.85 0.73 0.99 81 101393 4 0 1 3 30
RFA_00600 0.79 0.68 0.92 68 120221 15 0 6 9 32
RFA_00601 0.82 0.71 0.95 81 99150 9 0 4 5 33
RFA_00602 0.81 0.71 0.93 82 101387 10 0 6 4 34
TMR_00173 0.12 0.07 0.19 3 42179 23 0 13 10 39
TMR_00357 0.37 0.26 0.52 24 82982 24 7 15 2 68
TMR_00601 0.51 0.38 0.70 16 58973 33 2 5 26 26
TMR_00696 0.44 0.30 0.65 34 85026 19 2 16 1 80

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Performance of PknotsRG - scored lower in this pairwise comparison

1. Total counts & total scores for PknotsRG

Total Base Pair Counts
Total TP 14931
Total TN 17456106
Total FP 14721
Total FP CONTRA 1770
Total FP INCONS 10978
Total FP COMP 1973
Total FN 13946
Total Scores
MCC 0.527
Average MCC ± 95% Confidence Intervals 0.520 ± 0.019
Sensitivity 0.517
Positive Predictive Value 0.539
Nr of predictions 277

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2. Individual counts for PknotsRG [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00001 0.63 0.61 0.64 46 34119 33 3 23 7 29
ASE_00002 0.50 0.49 0.51 36 35440 40 5 30 5 37
ASE_00004 0.70 0.71 0.70 69 47796 32 9 21 2 28
ASE_00005 0.63 0.58 0.68 68 57870 38 0 32 6 49
ASE_00006 0.57 0.58 0.57 54 47491 44 7 34 3 39
ASE_00007 0.57 0.55 0.61 60 59586 43 1 38 4 50
ASE_00009 0.78 0.75 0.82 50 26045 13 0 11 2 17
ASE_00012 0.58 0.54 0.61 67 73811 49 2 40 7 56
ASE_00014 0.24 0.25 0.24 26 54178 82 8 73 1 80
ASE_00017 0.14 0.16 0.13 10 50964 85 8 58 19 54
ASE_00018 0.80 0.76 0.84 102 80479 22 3 17 2 32
ASE_00020 0.53 0.52 0.53 66 73796 58 8 50 0 60
ASE_00021 0.57 0.54 0.61 86 104056 61 7 47 7 74
ASE_00022 0.46 0.44 0.48 54 82915 65 6 53 6 70
ASE_00023 0.64 0.63 0.65 80 84131 47 5 39 3 47
ASE_00025 0.23 0.24 0.22 17 78528 115 12 49 54 54
ASE_00026 0.53 0.51 0.54 56 59582 55 1 46 8 54
ASE_00028 0.59 0.56 0.61 71 84550 53 4 41 8 55
ASE_00029 0.56 0.54 0.59 66 82916 48 4 42 2 56
ASE_00030 0.65 0.62 0.68 90 85358 45 3 40 2 55
ASE_00031 0.63 0.60 0.65 76 86619 50 2 39 9 50
ASE_00032 0.57 0.54 0.60 64 80094 47 6 36 5 54
ASE_00033 0.52 0.48 0.57 58 64879 45 5 38 2 63
ASE_00035 0.30 0.28 0.32 33 70398 76 11 58 7 85
ASE_00036 0.46 0.45 0.48 59 75731 68 8 57 3 73
ASE_00037 0.24 0.23 0.25 25 59239 79 3 73 3 85
ASE_00038 0.55 0.54 0.56 55 53529 45 4 40 1 46
ASE_00040 0.50 0.47 0.52 63 78882 64 5 53 6 70
ASE_00041 0.52 0.50 0.55 54 57532 48 2 42 4 54
ASE_00042 0.53 0.50 0.58 72 89975 54 3 50 1 73
ASE_00044 0.69 0.68 0.70 71 54513 35 3 28 4 34
ASE_00046 0.63 0.57 0.69 59 50317 27 2 25 0 44
ASE_00047 0.33 0.31 0.35 40 74190 76 5 70 1 90
ASE_00052 0.50 0.46 0.55 52 61330 48 2 41 5 60
ASE_00053 0.59 0.58 0.60 77 79273 54 5 46 3 56
ASE_00057 0.63 0.60 0.65 81 82090 49 8 36 5 53
ASE_00064 0.43 0.43 0.44 38 45364 53 5 44 4 51
ASE_00066 0.67 0.64 0.71 83 72273 35 4 30 1 47
ASE_00068 0.24 0.24 0.25 20 37596 59 5 54 0 65
ASE_00069 0.68 0.65 0.71 91 82899 44 5 33 6 49
ASE_00074 0.58 0.57 0.59 68 67781 47 6 41 0 51
ASE_00075 0.65 0.59 0.71 96 108676 46 2 37 7 66
ASE_00076 0.60 0.57 0.63 67 68158 42 2 38 2 51
ASE_00077 0.25 0.24 0.25 21 45067 67 7 55 5 65
ASE_00078 0.68 0.67 0.68 56 42989 31 5 21 5 27
ASE_00079 0.51 0.50 0.53 50 55517 44 5 39 0 50
ASE_00080 0.46 0.44 0.48 54 71519 61 5 53 3 69
ASE_00081 0.53 0.53 0.54 51 49676 44 5 38 1 46
ASE_00082 0.50 0.47 0.54 54 70400 60 1 45 14 62
ASE_00083 0.79 0.75 0.83 82 62382 26 2 15 9 28
ASE_00084 0.70 0.69 0.72 68 53534 29 6 20 3 31
ASE_00087 0.61 0.58 0.65 83 88283 49 5 39 5 61
ASE_00090 0.59 0.59 0.59 60 55509 47 2 40 5 41
ASE_00092 0.73 0.70 0.76 79 63442 30 0 25 5 34
ASE_00096 0.48 0.47 0.50 54 63437 58 4 51 3 61
ASE_00099 0.51 0.50 0.53 60 64506 56 6 48 2 60
ASE_00100 0.20 0.22 0.19 17 82125 115 16 57 42 59
ASE_00102 0.42 0.41 0.44 68 117699 89 8 80 1 98
ASE_00104 0.65 0.63 0.68 75 64151 36 3 32 1 44
ASE_00105 0.38 0.36 0.40 40 64160 66 9 52 5 71
ASE_00107 0.47 0.45 0.50 57 73039 57 2 55 0 70
ASE_00108 0.24 0.29 0.20 18 46881 83 21 51 11 45
ASE_00111 0.14 0.18 0.11 10 49998 88 24 54 10 47
ASE_00112 0.79 0.75 0.84 87 75362 23 5 12 6 29
ASE_00115 0.48 0.47 0.49 47 54520 56 1 47 8 54
ASE_00116 0.19 0.20 0.19 13 31558 58 2 53 3 53
ASE_00118 0.45 0.44 0.45 45 60627 57 4 50 3 57
ASE_00119 0.67 0.65 0.69 70 62734 33 1 30 2 38
ASE_00120 0.35 0.34 0.36 32 46883 56 9 47 0 62
ASE_00121 0.25 0.25 0.26 23 45061 68 9 57 2 69
ASE_00122 0.28 0.27 0.28 24 43280 61 4 57 0 64
ASE_00123 0.40 0.39 0.42 33 38424 50 2 44 4 52
ASE_00125 0.64 0.63 0.65 55 39255 30 4 26 0 33
ASE_00128 0.76 0.73 0.80 73 53210 25 2 16 7 27
ASE_00129 0.52 0.50 0.53 56 62730 53 5 44 4 55
ASE_00131 0.64 0.58 0.72 49 39272 29 0 19 10 36
ASE_00132 0.66 0.63 0.68 60 50315 30 4 24 2 35
ASE_00134 0.56 0.57 0.55 54 50305 49 4 40 5 41
ASE_00135 0.47 0.46 0.48 50 63085 59 8 47 4 59
ASE_00136 0.49 0.47 0.51 43 48121 50 1 40 9 49
ASE_00137 0.44 0.43 0.45 42 48423 53 5 46 2 56
ASE_00138 0.53 0.52 0.55 42 40393 35 4 31 0 39
ASE_00139 0.80 0.73 0.88 76 54199 15 2 8 5 28
ASE_00140 0.69 0.65 0.74 81 70767 33 3 25 5 44
ASE_00142 0.74 0.70 0.79 85 67054 26 4 18 4 37
ASE_00145 0.43 0.42 0.44 47 70019 64 6 53 5 64
ASE_00146 0.51 0.46 0.56 57 70775 47 0 44 3 67
ASE_00148 0.70 0.67 0.73 103 112433 42 4 35 3 51
ASE_00151 0.42 0.41 0.43 40 51911 52 12 40 0 58
ASE_00153 0.61 0.62 0.61 45 57556 71 2 27 42 28
ASE_00154 0.64 0.63 0.65 67 65238 39 4 32 3 40
ASE_00155 0.51 0.50 0.52 71 93391 71 10 56 5 71
ASE_00163 0.29 0.29 0.30 27 53211 72 7 56 9 66
ASE_00165 0.57 0.55 0.60 56 52881 39 7 31 1 45
ASE_00168 0.23 0.28 0.19 18 60629 92 25 54 13 46
ASE_00169 0.50 0.49 0.51 52 57190 53 7 42 4 55
ASE_00170 0.70 0.68 0.72 63 48741 25 2 22 1 30
ASE_00171 0.71 0.70 0.73 66 48425 25 5 20 0 28
ASE_00172 0.68 0.66 0.70 70 58896 35 4 26 5 36
ASE_00174 0.55 0.51 0.59 56 60980 39 3 36 0 53
ASE_00175 0.44 0.44 0.45 47 59926 62 6 52 4 60
ASE_00176 0.59 0.55 0.63 61 59934 39 5 31 3 49
ASE_00179 0.64 0.65 0.62 55 44164 34 7 27 0 29
ASE_00180 0.72 0.69 0.75 69 51268 29 2 21 6 31
ASE_00181 0.54 0.53 0.55 56 57528 50 3 43 4 50
ASE_00182 0.49 0.47 0.51 64 84129 65 6 56 3 72
ASE_00184 0.63 0.64 0.63 65 54511 39 10 29 0 37
ASE_00185 0.61 0.59 0.65 75 73420 43 5 36 2 53
ASE_00186 0.74 0.70 0.78 92 78885 31 3 23 5 40
ASE_00187 0.51 0.50 0.52 57 68526 57 7 45 5 58
ASE_00189 0.57 0.55 0.60 56 63097 42 9 28 5 46
ASE_00190 0.46 0.44 0.47 40 45366 45 8 37 0 50
ASE_00192 0.46 0.44 0.48 59 84544 69 10 53 6 74
ASE_00194 0.46 0.45 0.47 53 73423 64 8 52 4 66
ASE_00196 0.70 0.69 0.71 52 31553 24 2 19 3 23
ASE_00197 0.48 0.46 0.51 66 89124 66 4 59 3 79
ASE_00203 0.70 0.68 0.72 65 46575 29 6 19 4 31
ASE_00204 0.63 0.60 0.67 67 67796 38 7 26 5 45
ASE_00205 0.56 0.56 0.56 50 45967 44 7 32 5 40
ASE_00209 0.28 0.27 0.29 24 42989 58 4 54 0 64
ASE_00210 0.59 0.60 0.59 39 27195 28 6 21 1 26
ASE_00212 0.54 0.52 0.55 77 93822 66 5 57 4 71
ASE_00213 0.73 0.73 0.73 48 27195 19 6 12 1 18
ASE_00214 0.78 0.76 0.80 78 56182 28 3 17 8 25
ASE_00215 0.55 0.53 0.57 52 48425 42 4 35 3 47
ASE_00216 0.60 0.61 0.60 50 39256 36 8 26 2 32
ASE_00217 0.30 0.29 0.32 26 40388 60 6 50 4 64
ASE_00221 0.40 0.38 0.42 45 64514 65 3 58 4 72
ASE_00222 0.62 0.60 0.64 94 111954 55 9 44 2 63
ASE_00227 0.31 0.29 0.33 39 78884 80 5 75 0 94
ASE_00228 0.59 0.59 0.58 51 46883 37 14 23 0 35
ASE_00229 0.58 0.57 0.59 50 42401 39 5 30 4 37
ASE_00231 0.69 0.69 0.70 66 47801 28 5 23 0 30
ASE_00232 0.56 0.55 0.57 46 38422 38 3 32 3 38
ASE_00234 0.52 0.49 0.55 63 75351 56 2 50 4 66
ASE_00237 0.00 0.00 0.00 0 45672 99 25 56 18 56
ASE_00238 0.48 0.47 0.50 54 64152 58 4 51 3 60
ASE_00240 0.64 0.62 0.66 58 46577 37 2 28 7 35
ASE_00241 0.56 0.54 0.58 47 43875 43 0 34 9 40
ASE_00242 0.72 0.68 0.76 76 60975 27 3 21 3 36
ASE_00246 0.16 0.18 0.15 12 48124 82 19 50 13 55
ASE_00247 0.17 0.19 0.16 12 54210 91 16 47 28 52
ASE_00248 0.46 0.42 0.49 48 62384 49 3 46 0 66
ASE_00250 0.61 0.59 0.64 77 78883 46 4 39 3 54
ASE_00252 0.59 0.56 0.62 94 115289 62 5 52 5 74
ASE_00254 0.61 0.60 0.63 49 36778 33 5 24 4 33
ASE_00255 0.47 0.45 0.50 59 74572 60 7 53 0 71
ASE_00257 0.64 0.64 0.65 62 50944 34 0 34 0 35
ASE_00263 0.62 0.62 0.62 74 70380 47 5 41 1 46
ASE_00264 0.84 0.78 0.90 78 49054 24 0 9 15 22
ASE_00267 0.46 0.44 0.48 39 45069 51 5 37 9 49
ASE_00270 0.63 0.62 0.64 79 72267 45 8 36 1 49
ASE_00274 0.48 0.47 0.50 48 55515 48 8 40 0 55
ASE_00277 0.39 0.40 0.39 36 48113 58 9 47 2 55
ASE_00279 0.38 0.36 0.41 36 53213 58 1 51 6 65
ASE_00280 0.37 0.37 0.38 36 51908 62 6 53 3 62
ASE_00281 0.54 0.51 0.58 45 44473 39 0 33 6 43
ASE_00282 0.42 0.41 0.42 52 77692 72 6 65 1 75
ASE_00283 0.74 0.73 0.76 78 61673 27 5 20 2 29
ASE_00284 0.62 0.60 0.64 65 58210 43 4 32 7 43
ASE_00285 0.62 0.58 0.66 71 68899 43 2 34 7 51
ASE_00286 0.43 0.42 0.43 39 46574 61 3 49 9 53
ASE_00287 0.59 0.55 0.63 57 54855 40 0 34 6 46
ASE_00288 0.46 0.45 0.48 42 45968 47 3 43 1 51
ASE_00289 0.66 0.62 0.71 98 100886 44 4 37 3 59
ASE_00292 0.71 0.66 0.76 91 81690 34 4 25 5 47
ASE_00294 0.78 0.74 0.83 127 114328 29 3 23 3 44
ASE_00295 0.53 0.50 0.57 65 73805 53 5 45 3 66
ASE_00296 0.31 0.30 0.33 43 91677 88 8 78 2 102
ASE_00297 0.53 0.53 0.54 52 52878 50 3 42 5 46
ASE_00298 0.19 0.19 0.19 21 67420 90 9 78 3 92
ASE_00299 0.55 0.55 0.56 55 49357 48 8 35 5 45
ASE_00313 0.72 0.72 0.73 64 62393 46 6 18 22 25
ASE_00316 0.56 0.57 0.54 56 107777 87 13 34 40 42
ASE_00318 0.64 0.61 0.67 72 80092 40 13 23 4 46
ASE_00327 0.80 0.78 0.82 69 57207 34 4 11 19 20
ASE_00328 0.41 0.41 0.41 46 72659 73 3 63 7 66
ASE_00330 0.75 0.74 0.75 67 56191 42 3 19 20 23
ASE_00332 0.54 0.51 0.57 71 81686 59 2 51 6 67
ASE_00335 0.52 0.52 0.52 60 75350 64 13 43 8 56
ASE_00337 0.36 0.37 0.36 26 39268 58 4 42 12 45
ASE_00338 0.72 0.69 0.74 68 66338 41 7 17 17 30
ASE_00339 0.53 0.52 0.53 62 80084 65 5 49 11 57
ASE_00340 0.71 0.72 0.71 61 45970 34 7 18 9 24
ASE_00342 0.48 0.45 0.50 52 62378 51 1 50 0 63
ASE_00343 0.60 0.62 0.58 70 83316 60 9 41 10 43
ASE_00346 0.30 0.29 0.31 28 48115 64 7 55 2 69
ASE_00353 0.46 0.47 0.45 50 57860 60 11 49 0 57
ASE_00359 0.49 0.49 0.49 39 42698 46 3 38 5 41
ASE_00360 0.30 0.31 0.30 20 29337 50 11 35 4 45
ASE_00361 0.37 0.36 0.38 46 75345 78 9 66 3 81
ASE_00362 0.62 0.62 0.63 56 48116 36 6 27 3 35
ASE_00363 0.54 0.55 0.53 52 51262 46 5 41 0 42
ASE_00364 0.32 0.31 0.33 33 54184 72 7 61 4 72
ASE_00366 0.52 0.54 0.50 53 58547 55 12 41 2 45
ASE_00367 0.33 0.35 0.32 30 42976 65 8 57 0 56
ASE_00369 0.68 0.67 0.69 72 55841 37 2 30 5 35
ASE_00370 0.65 0.63 0.66 53 41825 27 5 22 0 31
ASE_00372 0.72 0.71 0.72 71 51905 30 5 22 3 29
ASE_00374 0.56 0.56 0.57 49 44764 37 8 29 0 39
ASE_00375 0.57 0.54 0.60 59 60280 42 6 33 3 51
ASE_00376 0.52 0.50 0.54 53 56855 48 4 41 3 52
ASE_00377 0.69 0.66 0.72 71 57531 34 3 25 6 36
ASE_00379 0.44 0.44 0.45 39 45969 55 7 41 7 50
ASE_00380 0.46 0.44 0.47 44 54853 54 1 48 5 55
ASE_00382 0.51 0.51 0.52 43 41822 43 6 34 3 41
ASE_00383 0.44 0.43 0.45 45 54516 59 4 50 5 60
ASE_00384 0.73 0.71 0.75 65 48429 27 4 18 5 27
ASE_00385 0.42 0.43 0.41 35 41819 52 6 45 1 46
ASE_00386 0.53 0.53 0.53 51 50306 51 4 42 5 45
ASE_00387 0.36 0.37 0.35 38 55837 70 6 64 0 66
ASE_00388 0.68 0.67 0.69 60 45666 32 1 26 5 29
ASE_00390 0.50 0.48 0.53 41 42117 44 6 31 7 44
ASE_00393 0.36 0.34 0.38 32 47810 59 3 50 6 61
ASE_00394 0.72 0.72 0.73 67 46879 28 3 22 3 26
ASE_00395 0.51 0.49 0.53 41 41539 45 1 35 9 43
ASE_00396 0.37 0.36 0.38 30 41536 55 5 45 5 53
ASE_00397 0.52 0.51 0.52 54 54511 50 7 43 0 51
ASE_00398 0.64 0.62 0.66 64 55848 36 1 32 3 40
ASE_00400 0.53 0.52 0.54 55 57868 48 5 42 1 51
ASE_00401 0.55 0.56 0.54 70 76898 60 13 47 0 56
ASE_00402 0.60 0.59 0.61 50 42404 35 4 28 3 35
ASE_00403 0.47 0.44 0.50 47 55851 51 3 44 4 60
ASE_00404 0.56 0.55 0.56 47 42987 42 0 37 5 38
ASE_00406 0.69 0.66 0.72 62 48742 33 2 22 9 32
ASE_00411 0.26 0.27 0.26 24 49362 69 12 57 0 65
ASE_00412 0.38 0.37 0.39 39 58212 60 13 47 0 66
ASE_00413 0.46 0.49 0.43 40 44457 54 14 40 0 41
ASE_00414 0.37 0.36 0.40 34 46274 59 9 43 7 61
ASE_00415 0.51 0.51 0.51 53 54843 52 7 43 2 50
ASE_00416 0.71 0.68 0.75 86 77306 36 1 28 7 41
ASE_00417 0.36 0.37 0.35 37 54508 73 10 60 3 63
ASE_00418 0.21 0.21 0.21 16 38703 67 8 54 5 59
ASE_00419 0.76 0.73 0.80 75 54852 23 4 15 4 28
ASE_00422 0.48 0.47 0.49 44 46881 51 5 41 5 50
ASE_00423 0.49 0.49 0.50 53 56847 56 9 44 3 56
ASE_00426 0.40 0.39 0.40 42 60971 62 5 57 0 66
ASE_00428 0.54 0.52 0.57 65 76521 54 5 45 4 60
ASE_00430 0.63 0.61 0.66 59 46881 36 5 26 5 38
ASE_00431 0.64 0.59 0.70 56 46280 36 3 21 12 39
ASE_00434 0.63 0.60 0.66 66 68165 46 9 25 12 44
ASE_00437 0.42 0.41 0.44 55 79275 71 4 67 0 80
ASE_00438 0.43 0.42 0.45 49 65957 60 6 54 0 67
ASE_00441 0.78 0.74 0.83 83 64161 28 1 16 11 29
ASE_00447 0.49 0.47 0.52 54 60274 55 1 49 5 62
ASE_00448 0.22 0.22 0.23 25 64151 91 6 79 6 87
ASE_00451 0.50 0.47 0.52 59 70763 57 3 51 3 66
CRW_00013 0.16 0.17 0.15 19 103617 114 25 79 10 96
CRW_00016 0.64 0.62 0.66 74 77309 50 5 33 12 46
CRW_00610 0.49 0.49 0.49 40 36233 43 7 35 1 41
CRW_00613 0.64 0.59 0.69 46 34913 29 1 20 8 32
CRW_00614 0.09 0.11 0.07 6 121690 145 21 54 70 51
CRW_00618 0.11 0.11 0.10 7 56211 83 13 49 21 54
CRW_00619 0.38 0.44 0.34 32 164930 138 28 35 75 41
CRW_00620 0.16 0.21 0.13 13 150871 158 31 60 67 50
CRW_00621 0.10 0.10 0.10 7 153109 156 13 52 91 64
CRW_00623 0.30 0.29 0.32 24 129720 119 11 40 68 59
CRW_00633 0.50 0.48 0.52 51 63447 50 10 38 2 55
CRW_00634 0.56 0.60 0.52 56 64513 53 17 34 2 38
CRW_00670 0.75 0.74 0.77 89 70009 30 5 22 3 31
CRW_00671 0.77 0.76 0.78 89 62721 30 6 19 5 28
CRW_00672 0.53 0.55 0.52 61 72273 60 21 35 4 50
CRW_00674 0.52 0.52 0.52 65 83310 63 12 49 2 59
CRW_00676 0.56 0.60 0.52 69 93396 67 13 50 4 46
CRW_00692 0.43 0.46 0.41 41 68536 66 18 40 8 49
PDB_00827 0.50 0.46 0.55 37 26961 31 1 29 1 44
PDB_00919 0.50 0.47 0.54 48 44164 44 3 38 3 55
RFA_00597 0.52 0.53 0.51 58 97789 83 8 48 27 51
RFA_00598 0.68 0.66 0.69 67 84569 57 6 24 27 34
RFA_00599 0.63 0.68 0.60 75 101349 70 18 33 19 36
RFA_00600 0.63 0.70 0.56 70 120170 88 32 23 33 30
RFA_00601 0.48 0.50 0.46 57 99111 86 21 46 19 57
RFA_00602 0.69 0.72 0.67 83 101351 61 10 31 20 33
TMR_00173 0.31 0.36 0.28 15 42141 67 16 23 28 27
TMR_00357 0.40 0.41 0.39 38 82931 75 22 37 16 54
TMR_00601 0.56 0.57 0.55 24 58952 77 2 18 57 18
TMR_00696 0.12 0.12 0.11 14 84955 125 19 90 16 100

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.