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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

  4. Performance of Vsfold4 - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(seed) & Vsfold4 [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(seed) Vsfold4
MCC 0.697 > 0.406
Average MCC ± 95% Confidence Intervals 0.694 ± 0.015 > 0.403 ± 0.015
Sensitivity 0.528 > 0.365
Positive Predictive Value 0.921 > 0.452
Total TP 14087 > 9755
Total TN 15326387 > 15320119
Total FP 1490 < 12759
Total FP CONTRA 166 < 1199
Total FP INCONS 1049 < 10616
Total FP COMP 275 < 944
Total FN 12608 < 16940
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of CentroidAlifold(seed) and Vsfold4. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(seed) and Vsfold4).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for CentroidAlifold(seed) and Vsfold4).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(seed) and Vsfold4. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(seed) and Vsfold4).

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Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(seed)

Total Base Pair Counts
Total TP 14087
Total TN 15326387
Total FP 1490
Total FP CONTRA 166
Total FP INCONS 1049
Total FP COMP 275
Total FN 12608
Total Scores
MCC 0.697
Average MCC ± 95% Confidence Intervals 0.694 ± 0.015
Sensitivity 0.528
Positive Predictive Value 0.921
Nr of predictions 259

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2. Individual counts for CentroidAlifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00001 0.81 0.65 1.00 49 34142 0 0 0 0 26
ASE_00002 0.82 0.67 1.00 49 35462 0 0 0 0 24
ASE_00004 0.61 0.45 0.83 44 47842 9 0 9 0 53
ASE_00005 0.75 0.57 0.97 67 57901 2 0 2 0 50
ASE_00006 0.58 0.44 0.76 41 47532 13 0 13 0 52
ASE_00007 0.83 0.71 0.98 78 59605 2 0 2 0 32
ASE_00009 0.79 0.67 0.94 45 26058 3 0 3 0 22
ASE_00012 0.75 0.59 0.95 73 73843 7 1 3 3 50
ASE_00014 0.74 0.58 0.95 61 54221 3 0 3 0 45
ASE_00017 0.79 0.69 0.90 44 50991 5 1 4 0 20
ASE_00018 0.78 0.60 1.00 81 80520 0 0 0 0 53
ASE_00020 0.63 0.43 0.93 54 73862 4 3 1 0 72
ASE_00022 0.80 0.65 1.00 80 82948 5 0 0 5 44
ASE_00023 0.47 0.35 0.63 45 84184 28 8 18 2 82
ASE_00025 0.69 0.58 0.84 41 78557 8 1 7 0 30
ASE_00026 0.80 0.67 0.96 74 59608 4 0 3 1 36
ASE_00028 0.80 0.64 1.00 81 84585 3 0 0 3 45
ASE_00029 0.45 0.34 0.61 41 82961 30 4 22 4 81
ASE_00030 0.66 0.49 0.90 71 85412 8 0 8 0 74
ASE_00031 0.51 0.37 0.72 46 86672 18 0 18 0 80
ASE_00032 0.38 0.27 0.54 32 80141 30 1 26 3 86
ASE_00033 0.80 0.65 0.99 79 64900 3 1 0 2 42
ASE_00035 0.77 0.64 0.94 75 70420 8 0 5 3 43
ASE_00036 0.75 0.58 0.99 76 75778 1 1 0 0 56
ASE_00037 0.84 0.71 1.00 78 59262 1 0 0 1 32
ASE_00038 0.74 0.54 1.00 55 53573 0 0 0 0 46
ASE_00040 0.77 0.59 1.00 79 78924 2 0 0 2 54
ASE_00041 0.77 0.64 0.92 69 57555 6 0 6 0 39
ASE_00042 0.65 0.49 0.87 71 90018 11 0 11 0 74
ASE_00044 0.83 0.70 1.00 73 54542 0 0 0 0 32
ASE_00046 0.73 0.62 0.86 64 50329 10 0 10 0 39
ASE_00047 0.70 0.52 0.93 68 74232 5 0 5 0 62
ASE_00052 0.75 0.63 0.91 70 61348 8 0 7 1 42
ASE_00053 0.71 0.54 0.92 72 79323 6 3 3 0 61
ASE_00057 0.73 0.57 0.93 77 82132 6 2 4 0 57
ASE_00064 0.77 0.60 1.00 53 45398 0 0 0 0 36
ASE_00066 0.75 0.56 1.00 73 72317 1 0 0 1 57
ASE_00068 0.54 0.38 0.78 32 37634 9 0 9 0 53
ASE_00069 0.75 0.57 0.98 80 82946 3 0 2 1 60
ASE_00074 0.83 0.69 1.00 82 67814 1 0 0 1 37
ASE_00076 0.69 0.48 1.00 57 68208 0 0 0 0 61
ASE_00077 0.79 0.64 0.96 55 45093 2 1 1 0 31
ASE_00078 0.83 0.69 1.00 57 43014 0 0 0 0 26
ASE_00079 0.63 0.47 0.84 47 55555 9 0 9 0 53
ASE_00080 0.45 0.30 0.66 37 71575 19 1 18 0 86
ASE_00081 0.77 0.59 1.00 57 49713 0 0 0 0 40
ASE_00082 0.66 0.43 1.00 50 70450 6 0 0 6 66
ASE_00083 0.72 0.52 1.00 57 62424 0 0 0 0 53
ASE_00084 0.75 0.57 0.98 56 53571 1 1 0 0 43
ASE_00087 0.60 0.38 0.95 54 88353 3 0 3 0 90
ASE_00090 0.75 0.56 1.00 57 55554 0 0 0 0 44
ASE_00092 0.70 0.50 0.98 56 63489 1 1 0 0 57
ASE_00096 0.63 0.44 0.89 51 63489 6 0 6 0 64
ASE_00099 0.82 0.67 1.00 80 64540 0 0 0 0 40
ASE_00100 0.72 0.58 0.90 44 82166 5 1 4 0 32
ASE_00104 0.81 0.67 0.99 80 64180 1 0 1 0 39
ASE_00105 0.55 0.40 0.76 44 64203 14 4 10 0 67
ASE_00107 0.78 0.63 0.96 80 73070 3 0 3 0 47
ASE_00108 0.79 0.70 0.90 44 46922 5 1 4 0 19
ASE_00111 0.83 0.74 0.93 42 50041 3 1 2 0 15
ASE_00112 0.50 0.34 0.71 40 75410 16 0 16 0 76
ASE_00115 0.74 0.54 1.00 55 54560 0 0 0 0 46
ASE_00116 0.86 0.76 0.98 50 31575 1 0 1 0 16
ASE_00118 0.68 0.49 0.94 50 60673 4 1 2 1 52
ASE_00119 0.66 0.44 0.98 48 62786 1 1 0 0 60
ASE_00120 0.79 0.64 0.98 60 46910 2 0 1 1 34
ASE_00121 0.81 0.66 0.98 61 45088 1 0 1 0 31
ASE_00122 0.80 0.64 1.00 56 43309 1 0 0 1 32
ASE_00123 0.68 0.48 0.95 41 38460 2 0 2 0 44
ASE_00125 0.67 0.47 0.95 41 39297 2 0 2 0 47
ASE_00128 0.73 0.54 1.00 54 53247 0 0 0 0 46
ASE_00129 0.71 0.50 1.00 56 62779 0 0 0 0 55
ASE_00131 0.65 0.44 0.97 37 39302 1 1 0 0 48
ASE_00132 0.76 0.59 0.98 56 50346 1 1 0 0 39
ASE_00134 0.69 0.54 0.89 51 50346 6 0 6 0 44
ASE_00135 0.53 0.39 0.74 42 63133 15 0 15 0 67
ASE_00136 0.75 0.59 0.95 54 48148 3 0 3 0 38
ASE_00137 0.70 0.53 0.93 52 48460 4 0 4 0 46
ASE_00138 0.79 0.63 1.00 51 40419 0 0 0 0 30
ASE_00139 0.73 0.54 1.00 56 54229 0 0 0 0 48
ASE_00140 0.64 0.43 0.95 54 70819 3 3 0 0 71
ASE_00142 0.77 0.61 0.97 75 67084 4 0 2 2 47
ASE_00145 0.77 0.59 1.00 66 70059 0 0 0 0 45
ASE_00146 0.78 0.62 0.97 77 70797 2 0 2 0 47
ASE_00151 0.80 0.70 0.92 69 51928 6 5 1 0 29
ASE_00153 0.67 0.53 0.85 39 57584 7 1 6 0 34
ASE_00154 0.75 0.59 0.95 63 65275 3 0 3 0 44
ASE_00155 0.68 0.46 1.00 66 93462 0 0 0 0 76
ASE_00163 0.77 0.59 1.00 55 53246 0 0 0 0 38
ASE_00165 0.69 0.50 0.94 51 52921 4 1 2 1 50
ASE_00168 0.79 0.69 0.90 44 60677 5 1 4 0 20
ASE_00169 0.65 0.48 0.88 51 57233 7 1 6 0 56
ASE_00170 0.78 0.60 1.00 56 48772 0 0 0 0 37
ASE_00171 0.76 0.59 1.00 55 48461 1 0 0 1 39
ASE_00172 0.72 0.53 0.98 56 58939 1 1 0 0 50
ASE_00174 0.60 0.43 0.82 47 61018 10 1 9 0 62
ASE_00175 0.71 0.51 0.98 55 59975 1 1 0 0 52
ASE_00176 0.71 0.50 1.00 55 59976 0 0 0 0 55
ASE_00179 0.79 0.63 0.98 53 44199 2 0 1 1 31
ASE_00180 0.73 0.54 0.98 54 51305 1 1 0 0 46
ASE_00181 0.71 0.52 0.96 55 57573 3 2 0 1 51
ASE_00182 0.61 0.40 0.95 54 84198 3 0 3 0 82
ASE_00184 0.75 0.56 1.00 57 54558 0 0 0 0 45
ASE_00185 0.64 0.41 0.98 53 73482 1 1 0 0 75
ASE_00186 0.66 0.51 0.86 67 78925 14 0 11 3 65
ASE_00187 0.69 0.51 0.92 59 68571 5 1 4 0 56
ASE_00189 0.76 0.62 0.94 63 63123 8 0 4 4 39
ASE_00190 0.74 0.54 1.00 49 45402 3 0 0 3 41
ASE_00192 0.51 0.35 0.75 47 84603 20 0 16 4 86
ASE_00194 0.72 0.53 0.97 63 73471 7 0 2 5 56
ASE_00196 0.82 0.69 0.96 52 31572 2 0 2 0 23
ASE_00197 0.63 0.46 0.86 67 89175 12 0 11 1 78
ASE_00203 0.72 0.55 0.93 53 46608 4 2 2 0 43
ASE_00204 0.73 0.55 0.97 62 67832 7 1 1 5 50
ASE_00205 0.82 0.67 1.00 60 45996 1 0 0 1 30
ASE_00209 0.83 0.69 0.98 61 43009 1 0 1 0 27
ASE_00210 0.74 0.65 0.86 42 27212 9 0 7 2 23
ASE_00212 0.63 0.45 0.89 66 93887 9 0 8 1 82
ASE_00213 0.83 0.71 0.98 47 27213 3 0 1 2 19
ASE_00214 0.73 0.54 0.98 56 56223 2 1 0 1 47
ASE_00215 0.51 0.32 0.82 32 48477 7 0 7 0 67
ASE_00216 0.81 0.66 1.00 54 39286 0 0 0 0 28
ASE_00217 0.82 0.67 1.00 60 40410 1 0 0 1 30
ASE_00221 0.83 0.70 0.99 82 64537 1 0 1 0 35
ASE_00227 0.57 0.43 0.76 57 78928 18 0 18 0 76
ASE_00228 0.72 0.57 0.91 49 46917 6 3 2 1 37
ASE_00229 0.78 0.61 1.00 53 42433 2 0 0 2 34
ASE_00231 0.59 0.45 0.78 43 47840 12 0 12 0 53
ASE_00232 0.81 0.65 1.00 55 38448 0 0 0 0 29
ASE_00234 0.64 0.43 0.95 55 75408 3 3 0 0 74
ASE_00237 0.83 0.73 0.93 41 45709 3 1 2 0 15
ASE_00238 0.61 0.44 0.86 50 64203 8 2 6 0 64
ASE_00240 0.62 0.48 0.79 45 46608 12 0 12 0 48
ASE_00241 0.79 0.64 0.98 56 43899 1 0 1 0 31
ASE_00242 0.85 0.72 1.00 81 60994 1 0 0 1 31
ASE_00246 0.79 0.67 0.92 45 48156 4 1 3 0 22
ASE_00247 0.79 0.69 0.90 44 54236 5 1 4 0 20
ASE_00248 0.84 0.71 1.00 81 62400 1 0 0 1 33
ASE_00250 0.72 0.56 0.91 74 78922 8 1 6 1 57
ASE_00254 0.81 0.66 1.00 54 36802 0 0 0 0 28
ASE_00255 0.64 0.51 0.80 66 74609 16 0 16 0 64
ASE_00257 0.68 0.52 0.91 50 50985 5 1 4 0 47
ASE_00263 0.68 0.47 0.98 56 70443 1 1 0 0 64
ASE_00264 0.58 0.40 0.85 40 49094 8 0 7 1 60
ASE_00267 0.80 0.64 1.00 56 45094 0 0 0 0 32
ASE_00270 0.55 0.34 0.90 43 72342 6 0 5 1 85
ASE_00274 0.71 0.53 0.95 55 55553 3 3 0 0 48
ASE_00277 0.73 0.57 0.93 52 48149 4 3 1 0 39
ASE_00279 0.73 0.54 0.98 55 53245 1 0 1 0 46
ASE_00280 0.74 0.57 0.97 56 51945 2 1 1 0 42
ASE_00281 0.78 0.63 0.98 55 44495 1 0 1 0 33
ASE_00282 0.66 0.45 0.98 57 77757 1 1 0 0 70
ASE_00283 0.72 0.52 0.98 56 61719 1 0 1 0 51
ASE_00284 0.72 0.53 0.98 57 58253 1 1 0 0 51
ASE_00285 0.68 0.47 1.00 57 68949 0 0 0 0 65
ASE_00286 0.78 0.61 1.00 56 46609 0 0 0 0 36
ASE_00287 0.67 0.50 0.89 51 54889 6 0 6 0 52
ASE_00288 0.75 0.58 0.96 54 46000 2 2 0 0 39
ASE_00292 0.76 0.58 1.00 80 81730 1 0 0 1 58
ASE_00295 0.77 0.59 1.00 77 73843 0 0 0 0 54
ASE_00296 0.73 0.54 0.98 79 91725 3 0 2 1 66
ASE_00297 0.61 0.45 0.83 44 52922 9 2 7 0 54
ASE_00298 0.70 0.50 0.98 56 67471 1 1 0 0 57
ASE_00299 0.55 0.44 0.70 44 49392 19 0 19 0 56
ASE_00313 0.50 0.34 0.75 30 62441 14 2 8 4 59
ASE_00318 0.79 0.62 1.00 73 80127 6 0 0 6 45
ASE_00327 0.61 0.43 0.86 38 57247 11 0 6 5 51
ASE_00328 0.83 0.70 1.00 78 72693 5 0 0 5 34
ASE_00330 0.66 0.48 0.91 43 56233 5 0 4 1 47
ASE_00332 0.78 0.60 1.00 83 81727 0 0 0 0 55
ASE_00335 0.81 0.66 1.00 77 75389 7 0 0 7 39
ASE_00337 0.57 0.44 0.76 31 39299 18 0 10 8 40
ASE_00338 0.51 0.33 0.80 32 66390 8 0 8 0 66
ASE_00339 0.58 0.46 0.72 55 80124 22 7 14 1 64
ASE_00340 0.73 0.56 0.94 48 46005 7 0 3 4 37
ASE_00342 0.84 0.71 1.00 82 62399 0 0 0 0 33
ASE_00343 0.37 0.27 0.51 31 83375 32 2 28 2 82
ASE_00346 0.61 0.49 0.75 48 48141 16 0 16 0 49
ASE_00353 0.72 0.52 0.98 56 57913 2 1 0 1 51
ASE_00359 0.77 0.61 0.98 49 42728 2 0 1 1 31
ASE_00360 0.87 0.77 0.98 50 29352 1 0 1 0 15
ASE_00361 0.65 0.43 0.98 55 75410 1 1 0 0 72
ASE_00362 0.78 0.62 1.00 56 48149 1 0 0 1 35
ASE_00363 0.70 0.54 0.89 51 51303 6 0 6 0 43
ASE_00364 0.66 0.49 0.89 51 54228 6 1 5 0 54
ASE_00366 0.69 0.53 0.90 52 58595 6 2 4 0 46
ASE_00367 0.81 0.65 1.00 56 43015 1 0 0 1 30
ASE_00369 0.73 0.53 1.00 57 55888 0 0 0 0 50
ASE_00370 0.78 0.62 0.98 52 41852 1 0 1 0 32
ASE_00372 0.73 0.54 0.98 54 51948 1 0 1 0 46
ASE_00374 0.78 0.60 1.00 53 44797 0 0 0 0 35
ASE_00375 0.71 0.51 1.00 56 60322 1 0 0 1 54
ASE_00376 0.68 0.50 0.93 53 56896 4 0 4 0 52
ASE_00377 0.67 0.50 0.91 53 57572 5 1 4 0 54
ASE_00379 0.79 0.63 1.00 56 46000 1 0 0 1 33
ASE_00380 0.75 0.57 1.00 56 54890 0 0 0 0 43
ASE_00382 0.80 0.64 1.00 54 41851 1 0 0 1 30
ASE_00383 0.74 0.54 1.00 57 54558 0 0 0 0 48
ASE_00384 0.78 0.61 1.00 56 48460 0 0 0 0 36
ASE_00385 0.71 0.56 0.90 45 41855 5 0 5 0 36
ASE_00386 0.77 0.59 1.00 57 50346 0 0 0 0 39
ASE_00387 0.63 0.46 0.87 48 55890 7 0 7 0 56
ASE_00388 0.77 0.60 1.00 53 45700 1 0 0 1 36
ASE_00390 0.78 0.62 0.98 53 42141 1 0 1 0 32
ASE_00393 0.71 0.56 0.91 52 47838 5 0 5 0 41
ASE_00394 0.76 0.58 1.00 54 46917 0 0 0 0 39
ASE_00395 0.80 0.64 1.00 54 41562 0 0 0 0 30
ASE_00396 0.81 0.65 1.00 54 41562 0 0 0 0 29
ASE_00397 0.74 0.54 1.00 57 54558 0 0 0 0 48
ASE_00398 0.72 0.52 1.00 54 55891 0 0 0 0 50
ASE_00400 0.72 0.52 1.00 55 57915 1 0 0 1 51
ASE_00401 0.62 0.40 0.96 50 76976 2 1 1 0 76
ASE_00402 0.80 0.65 1.00 55 42431 0 0 0 0 30
ASE_00403 0.73 0.53 1.00 57 55888 0 0 0 0 50
ASE_00404 0.80 0.65 1.00 55 43016 1 0 0 1 30
ASE_00406 0.78 0.61 1.00 57 48771 0 0 0 0 37
ASE_00411 0.67 0.55 0.82 49 49395 11 5 6 0 40
ASE_00412 0.63 0.47 0.84 49 58253 9 2 7 0 56
ASE_00413 0.72 0.57 0.90 46 44500 7 2 3 2 35
ASE_00414 0.58 0.44 0.76 42 46305 13 3 10 0 53
ASE_00415 0.57 0.40 0.80 41 54895 10 0 10 0 62
ASE_00416 0.76 0.61 0.94 78 77338 5 1 4 0 49
ASE_00417 0.80 0.65 0.98 65 54549 1 0 1 0 35
ASE_00418 0.81 0.67 0.98 50 38730 1 0 1 0 25
ASE_00419 0.67 0.50 0.89 51 54889 6 2 4 0 52
ASE_00422 0.74 0.57 0.96 54 46915 3 0 2 1 40
ASE_00423 0.77 0.64 0.93 70 56878 6 0 5 1 39
ASE_00426 0.52 0.41 0.68 44 61010 22 5 16 1 64
ASE_00428 0.77 0.62 0.94 78 76553 5 1 4 0 47
ASE_00430 0.73 0.55 0.98 53 46917 1 0 1 0 44
ASE_00431 0.56 0.44 0.71 42 46301 17 7 10 0 53
ASE_00434 0.74 0.61 0.89 67 68190 14 0 8 6 43
ASE_00437 0.52 0.40 0.67 54 79320 27 0 27 0 81
ASE_00438 0.62 0.42 0.92 49 66013 4 1 3 0 67
ASE_00441 0.65 0.44 0.96 49 64210 3 0 2 1 63
ASE_00447 0.84 0.71 1.00 82 60296 0 0 0 0 34
ASE_00448 0.81 0.69 0.95 77 64180 4 0 4 0 35
ASE_00451 0.79 0.64 0.96 80 70793 3 0 3 0 45
CRW_00016 0.36 0.20 0.65 24 77384 16 1 12 3 96
CRW_00610 0.51 0.33 0.77 27 36280 11 1 7 3 54
CRW_00613 0.48 0.32 0.71 25 34945 14 0 10 4 53
CRW_00618 0.41 0.28 0.61 17 56252 12 3 8 1 44
CRW_00633 0.31 0.17 0.58 18 63515 14 2 11 1 88
CRW_00634 0.35 0.20 0.61 19 64589 20 1 11 8 75
CRW_00670 0.49 0.28 0.89 33 70088 8 0 4 4 87
CRW_00671 0.50 0.28 0.89 33 62798 8 0 4 4 84
CRW_00672 0.51 0.30 0.89 33 72353 8 0 4 4 78
CRW_00674 0.29 0.16 0.54 20 83399 20 6 11 3 104
CRW_00676 0.35 0.17 0.69 20 93499 20 0 9 11 95
CRW_00692 0.39 0.22 0.69 20 68606 20 0 9 11 70
PDB_00827 0.58 0.40 0.84 32 26990 6 1 5 0 49
PDB_00919 0.49 0.35 0.69 36 44201 18 0 16 2 67
RFA_00597 0.73 0.64 0.83 70 97819 19 0 14 5 39
RFA_00598 0.72 0.63 0.81 64 84587 26 0 15 11 37
RFA_00601 0.82 0.71 0.95 81 99150 9 0 4 5 33
TMR_00173 0.12 0.07 0.19 3 42179 23 0 13 10 39
TMR_00357 0.37 0.26 0.52 24 82982 24 7 15 2 68
TMR_00601 0.51 0.38 0.70 16 58973 33 2 5 26 26
TMR_00696 0.44 0.30 0.65 34 85026 19 2 16 1 80

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Performance of Vsfold4 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold4

Total Base Pair Counts
Total TP 9755
Total TN 15320119
Total FP 12759
Total FP CONTRA 1199
Total FP INCONS 10616
Total FP COMP 944
Total FN 16940
Total Scores
MCC 0.406
Average MCC ± 95% Confidence Intervals 0.403 ± 0.015
Sensitivity 0.365
Positive Predictive Value 0.452
Nr of predictions 259

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2. Individual counts for Vsfold4 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00001 0.52 0.45 0.60 34 34134 27 5 18 4 41
ASE_00002 0.33 0.30 0.37 22 35451 38 2 36 0 51
ASE_00004 0.66 0.59 0.74 57 47818 20 1 19 0 40
ASE_00005 0.31 0.26 0.36 31 57883 60 1 55 4 86
ASE_00006 0.40 0.37 0.45 34 47510 43 0 42 1 59
ASE_00007 0.36 0.33 0.40 36 59596 57 1 52 4 74
ASE_00009 0.20 0.18 0.22 12 26051 43 3 40 0 55
ASE_00012 0.34 0.30 0.39 37 73826 62 2 55 5 86
ASE_00014 0.38 0.36 0.41 38 54192 56 7 48 1 68
ASE_00017 0.16 0.16 0.16 10 50976 69 14 40 15 54
ASE_00018 0.48 0.43 0.54 57 80496 48 2 46 0 77
ASE_00020 0.41 0.36 0.48 45 73827 48 1 47 0 81
ASE_00022 0.48 0.41 0.57 51 82938 42 5 34 3 73
ASE_00023 0.41 0.39 0.43 49 84141 67 5 60 2 78
ASE_00025 0.30 0.28 0.31 20 78542 82 17 27 38 51
ASE_00026 0.43 0.37 0.49 41 59601 43 11 32 0 69
ASE_00028 0.34 0.30 0.38 38 84565 63 6 57 0 88
ASE_00029 0.29 0.26 0.33 32 82932 64 7 57 0 90
ASE_00030 0.53 0.46 0.61 66 85383 42 5 37 0 79
ASE_00031 0.50 0.45 0.56 57 86635 46 1 43 2 69
ASE_00032 0.43 0.39 0.47 46 80103 52 5 46 1 72
ASE_00033 0.39 0.34 0.44 41 64887 53 1 51 1 80
ASE_00035 0.26 0.24 0.29 28 70403 69 3 66 0 90
ASE_00036 0.37 0.33 0.42 44 75751 61 6 54 1 88
ASE_00037 0.31 0.26 0.37 29 59262 51 0 49 2 81
ASE_00038 0.47 0.44 0.51 44 53541 45 0 43 2 57
ASE_00040 0.42 0.37 0.49 49 78903 51 1 50 0 84
ASE_00041 0.29 0.25 0.34 27 57551 52 8 44 0 81
ASE_00042 0.44 0.38 0.51 55 89992 56 2 51 3 90
ASE_00044 0.54 0.52 0.57 55 54518 46 3 39 4 50
ASE_00046 0.32 0.26 0.39 27 50334 43 3 39 1 76
ASE_00047 0.27 0.23 0.31 30 74208 67 2 65 0 100
ASE_00052 0.35 0.30 0.41 34 61343 49 7 41 1 78
ASE_00053 0.54 0.47 0.63 62 79303 37 7 29 1 71
ASE_00057 0.50 0.45 0.57 60 82109 48 7 39 2 74
ASE_00064 0.47 0.42 0.54 37 45382 38 0 32 6 52
ASE_00066 0.49 0.42 0.56 55 72292 44 0 43 1 75
ASE_00068 0.35 0.29 0.41 25 37614 39 1 35 3 60
ASE_00069 0.44 0.37 0.53 52 82930 47 7 39 1 88
ASE_00074 0.43 0.39 0.47 47 67797 52 2 50 0 72
ASE_00076 0.35 0.32 0.39 38 68168 59 6 53 0 80
ASE_00077 0.27 0.26 0.30 22 45076 56 5 47 4 64
ASE_00078 0.32 0.30 0.35 25 42999 52 3 44 5 58
ASE_00079 0.42 0.39 0.46 39 55526 46 4 42 0 61
ASE_00080 0.37 0.32 0.43 39 71540 52 2 50 0 84
ASE_00081 0.39 0.35 0.45 34 49694 42 3 39 0 63
ASE_00082 0.39 0.34 0.44 39 70412 57 1 48 8 77
ASE_00083 0.55 0.50 0.60 55 62389 41 5 32 4 55
ASE_00084 0.51 0.44 0.59 44 53554 35 3 27 5 55
ASE_00087 0.42 0.35 0.52 50 88313 51 2 45 4 94
ASE_00090 0.48 0.46 0.51 46 55521 46 4 40 2 55
ASE_00092 0.51 0.46 0.58 52 63456 38 10 28 0 61
ASE_00096 0.56 0.50 0.62 58 63453 35 0 35 0 57
ASE_00099 0.58 0.53 0.63 64 64518 39 5 33 1 56
ASE_00100 0.34 0.32 0.38 24 82151 96 4 36 56 52
ASE_00104 0.51 0.45 0.57 54 64167 40 3 37 0 65
ASE_00105 0.32 0.29 0.37 32 64174 57 6 49 2 79
ASE_00107 0.41 0.36 0.46 46 73053 54 2 52 0 81
ASE_00108 0.25 0.25 0.25 16 46908 69 10 37 22 47
ASE_00111 0.17 0.19 0.15 11 50013 75 25 37 13 46
ASE_00112 0.49 0.43 0.56 50 75376 41 4 36 1 66
ASE_00115 0.43 0.39 0.49 39 54535 48 6 35 7 62
ASE_00116 0.17 0.15 0.19 10 31573 43 2 41 0 56
ASE_00118 0.37 0.35 0.40 36 60636 54 4 50 0 66
ASE_00119 0.72 0.63 0.82 68 62752 20 1 14 5 40
ASE_00120 0.35 0.31 0.39 29 46897 45 3 42 0 65
ASE_00121 0.20 0.17 0.22 16 45078 58 4 52 2 76
ASE_00122 0.49 0.42 0.58 37 43301 28 1 26 1 51
ASE_00123 0.33 0.29 0.38 25 38437 45 0 41 4 60
ASE_00125 0.41 0.38 0.45 33 39267 40 2 38 0 55
ASE_00128 0.47 0.41 0.53 41 53224 39 4 32 3 59
ASE_00129 0.55 0.49 0.61 54 62747 34 5 29 0 57
ASE_00131 0.53 0.46 0.61 39 39276 30 4 21 5 46
ASE_00132 0.55 0.49 0.60 47 50325 33 4 27 2 48
ASE_00134 0.46 0.41 0.51 39 50326 42 5 33 4 56
ASE_00135 0.38 0.35 0.42 38 63100 57 8 44 5 71
ASE_00136 0.52 0.47 0.59 43 48132 39 1 29 9 49
ASE_00137 0.52 0.48 0.56 47 48432 37 0 37 0 51
ASE_00138 0.42 0.38 0.47 31 40404 37 5 30 2 50
ASE_00139 0.57 0.49 0.66 51 54208 29 1 25 3 53
ASE_00140 0.42 0.37 0.48 46 70780 50 4 46 0 79
ASE_00142 0.50 0.44 0.57 54 67066 41 6 35 0 68
ASE_00145 0.25 0.23 0.27 25 70033 69 3 64 2 86
ASE_00146 0.30 0.26 0.35 32 70784 61 2 58 1 92
ASE_00151 0.43 0.39 0.47 38 51922 43 11 32 0 60
ASE_00153 0.38 0.37 0.39 27 57561 65 9 33 23 46
ASE_00154 0.34 0.30 0.40 32 65260 50 5 44 1 75
ASE_00155 0.31 0.27 0.36 39 93419 73 2 68 3 103
ASE_00163 0.36 0.32 0.39 30 53225 50 8 38 4 63
ASE_00165 0.43 0.40 0.46 40 52888 48 6 41 1 61
ASE_00168 0.31 0.34 0.29 22 60650 75 19 35 21 42
ASE_00169 0.54 0.47 0.63 50 57211 31 2 28 1 57
ASE_00170 0.47 0.44 0.50 41 48746 41 4 37 0 52
ASE_00171 0.39 0.33 0.46 31 48449 40 2 34 4 63
ASE_00172 0.44 0.39 0.51 41 58916 40 5 34 1 65
ASE_00174 0.42 0.38 0.47 41 60988 46 2 44 0 68
ASE_00175 0.41 0.37 0.46 40 59944 48 0 47 1 67
ASE_00176 0.56 0.52 0.61 57 59937 38 0 37 1 53
ASE_00179 0.57 0.51 0.63 43 44185 25 5 20 0 41
ASE_00180 0.38 0.36 0.41 36 51273 52 4 47 1 64
ASE_00181 0.49 0.45 0.52 48 57538 48 2 42 4 58
ASE_00182 0.41 0.35 0.48 47 84158 50 6 44 0 89
ASE_00184 0.50 0.45 0.56 46 54533 41 1 35 5 56
ASE_00185 0.39 0.32 0.47 41 73448 49 2 45 2 87
ASE_00186 0.34 0.30 0.38 40 78899 66 3 61 2 92
ASE_00187 0.25 0.23 0.28 26 68543 67 7 59 1 89
ASE_00189 0.28 0.25 0.31 26 63107 57 4 53 0 76
ASE_00190 0.42 0.37 0.49 33 45383 38 7 28 3 57
ASE_00192 0.26 0.23 0.30 30 84565 77 7 64 6 103
ASE_00194 0.45 0.40 0.51 48 73442 50 9 37 4 71
ASE_00196 0.17 0.15 0.19 11 31569 47 4 42 1 64
ASE_00197 0.38 0.33 0.44 48 89143 64 2 60 2 97
ASE_00203 0.48 0.44 0.52 42 46584 39 0 39 0 54
ASE_00204 0.38 0.32 0.45 36 67816 48 12 32 4 76
ASE_00205 0.19 0.18 0.20 16 45976 65 6 58 1 74
ASE_00209 0.29 0.25 0.33 22 43004 45 2 43 0 66
ASE_00210 0.10 0.09 0.11 6 27207 50 7 41 2 59
ASE_00212 0.33 0.29 0.39 43 93850 70 5 63 2 105
ASE_00213 0.32 0.30 0.34 20 27203 40 10 28 2 46
ASE_00214 0.63 0.57 0.69 59 56194 32 2 25 5 44
ASE_00215 0.47 0.41 0.53 41 48438 38 7 30 1 58
ASE_00216 0.58 0.54 0.63 44 39270 27 0 26 1 38
ASE_00217 0.24 0.21 0.28 19 40402 50 4 45 1 71
ASE_00221 0.38 0.32 0.44 38 64533 49 3 46 0 79
ASE_00227 0.38 0.33 0.44 44 78904 55 3 52 0 89
ASE_00228 0.35 0.33 0.37 28 46896 49 13 34 2 58
ASE_00229 0.58 0.52 0.64 45 42416 27 1 24 2 42
ASE_00231 0.66 0.63 0.71 60 47810 25 8 17 0 36
ASE_00232 0.47 0.44 0.50 37 38429 37 6 31 0 47
ASE_00234 0.32 0.26 0.40 33 75384 49 2 47 0 96
ASE_00237 0.33 0.38 0.30 21 45683 62 15 34 13 35
ASE_00238 0.34 0.31 0.39 35 64171 55 3 52 0 79
ASE_00240 0.29 0.26 0.33 24 46593 49 2 46 1 69
ASE_00241 0.35 0.31 0.40 27 43889 44 8 32 4 60
ASE_00242 0.47 0.43 0.53 48 60984 43 4 39 0 64
ASE_00246 0.28 0.27 0.29 18 48142 61 11 34 16 49
ASE_00247 0.35 0.34 0.35 22 54222 70 14 27 29 42
ASE_00248 0.41 0.36 0.48 41 62395 48 1 44 3 73
ASE_00250 0.47 0.43 0.53 56 78897 53 6 44 3 75
ASE_00254 0.34 0.30 0.38 25 36790 46 4 37 5 57
ASE_00255 0.33 0.29 0.38 38 74591 62 9 53 0 92
ASE_00257 0.54 0.47 0.62 46 50966 28 2 26 0 51
ASE_00263 0.37 0.33 0.40 40 70401 59 6 53 0 80
ASE_00264 0.26 0.25 0.28 25 49051 68 2 63 3 75
ASE_00267 0.38 0.34 0.43 30 45081 47 3 36 8 58
ASE_00270 0.39 0.36 0.43 46 72283 61 4 57 0 82
ASE_00274 0.38 0.34 0.42 35 55527 49 4 45 0 68
ASE_00277 0.31 0.29 0.33 26 48127 52 8 44 0 65
ASE_00279 0.26 0.23 0.31 23 53226 53 4 48 1 78
ASE_00280 0.60 0.55 0.65 54 51920 29 1 28 0 44
ASE_00281 0.60 0.51 0.71 45 44488 23 0 18 5 43
ASE_00282 0.40 0.35 0.46 45 77717 53 6 47 0 82
ASE_00283 0.41 0.36 0.48 38 61697 41 3 38 0 69
ASE_00284 0.20 0.18 0.22 19 58225 67 1 66 0 89
ASE_00285 0.49 0.43 0.56 52 68913 41 1 40 0 70
ASE_00286 0.45 0.40 0.51 37 46592 40 4 32 4 55
ASE_00287 0.40 0.34 0.47 35 54872 41 0 39 2 68
ASE_00288 0.52 0.47 0.57 44 45979 33 6 27 0 49
ASE_00292 0.48 0.41 0.56 56 81710 46 2 42 2 82
ASE_00295 0.40 0.35 0.46 46 73821 55 1 52 2 85
ASE_00296 0.43 0.38 0.48 55 91692 59 2 57 0 90
ASE_00297 0.50 0.47 0.53 46 52889 40 3 37 0 52
ASE_00298 0.38 0.33 0.44 37 67443 51 0 48 3 76
ASE_00299 0.28 0.26 0.30 26 49368 61 8 53 0 74
ASE_00313 0.35 0.33 0.37 29 62403 66 11 38 17 60
ASE_00318 0.38 0.35 0.41 41 80101 61 5 53 3 77
ASE_00327 0.36 0.34 0.39 30 57215 57 4 42 11 59
ASE_00328 0.43 0.39 0.48 44 72679 54 4 44 6 68
ASE_00330 0.30 0.28 0.33 25 56204 62 4 47 11 65
ASE_00332 0.43 0.39 0.48 54 81698 59 2 56 1 84
ASE_00335 0.35 0.32 0.39 37 75372 61 4 53 4 79
ASE_00337 0.47 0.48 0.47 34 39268 45 7 31 7 37
ASE_00338 0.28 0.27 0.31 26 66345 73 12 47 14 72
ASE_00339 0.38 0.34 0.42 41 80103 57 7 49 1 78
ASE_00340 0.43 0.38 0.48 32 45990 34 9 25 0 53
ASE_00342 0.40 0.35 0.45 40 62393 49 0 48 1 75
ASE_00343 0.43 0.41 0.46 46 83336 61 5 49 7 67
ASE_00346 0.23 0.21 0.26 20 48128 58 3 54 1 77
ASE_00353 0.57 0.54 0.61 58 57875 37 6 31 0 49
ASE_00359 0.36 0.34 0.39 27 42708 43 4 39 0 53
ASE_00360 0.20 0.20 0.21 13 29342 50 10 38 2 52
ASE_00361 0.37 0.32 0.43 41 75371 54 2 52 0 86
ASE_00362 0.54 0.52 0.57 47 48123 35 5 30 0 44
ASE_00363 0.50 0.46 0.54 43 51281 42 6 30 6 51
ASE_00364 0.37 0.34 0.40 36 54195 54 3 51 0 69
ASE_00366 0.34 0.33 0.35 32 58562 59 8 51 0 66
ASE_00367 0.30 0.27 0.33 23 43001 51 5 42 4 63
ASE_00369 0.54 0.49 0.60 52 55859 37 1 33 3 55
ASE_00370 0.41 0.37 0.46 31 41837 42 5 32 5 53
ASE_00372 0.44 0.40 0.48 40 51919 49 1 43 5 60
ASE_00374 0.45 0.41 0.50 36 44778 38 4 32 2 52
ASE_00375 0.61 0.55 0.67 61 60287 36 1 29 6 49
ASE_00376 0.59 0.53 0.66 56 56868 33 4 25 4 49
ASE_00377 0.67 0.63 0.73 67 57538 29 3 22 4 40
ASE_00379 0.33 0.30 0.36 27 45981 50 7 41 2 62
ASE_00380 0.56 0.52 0.61 51 54863 34 7 25 2 48
ASE_00382 0.63 0.56 0.71 47 41839 25 0 19 6 37
ASE_00383 0.47 0.43 0.51 45 54527 45 1 42 2 60
ASE_00384 0.53 0.47 0.61 43 48445 36 2 26 8 49
ASE_00385 0.39 0.32 0.48 26 41851 28 6 22 0 55
ASE_00386 0.43 0.39 0.47 37 50325 46 7 34 5 59
ASE_00387 0.40 0.37 0.44 38 55858 49 8 41 0 66
ASE_00388 0.49 0.44 0.55 39 45682 39 1 31 7 50
ASE_00390 0.43 0.38 0.48 32 42129 39 3 31 5 53
ASE_00393 0.34 0.30 0.39 28 47824 49 1 42 6 65
ASE_00394 0.37 0.32 0.42 30 46899 45 2 40 3 63
ASE_00395 0.43 0.39 0.48 33 41547 42 3 33 6 51
ASE_00396 0.45 0.42 0.49 35 41544 40 7 30 3 48
ASE_00397 0.34 0.31 0.38 33 54528 55 4 50 1 72
ASE_00398 0.56 0.50 0.62 52 55861 35 5 27 3 52
ASE_00400 0.51 0.47 0.56 50 57881 43 4 35 4 56
ASE_00401 0.51 0.48 0.54 60 76917 51 4 47 0 66
ASE_00402 0.39 0.34 0.44 29 42420 39 5 32 2 56
ASE_00403 0.31 0.27 0.36 29 55864 57 1 51 5 78
ASE_00404 0.28 0.26 0.31 22 43000 53 7 42 4 63
ASE_00406 0.69 0.63 0.77 59 48751 24 0 18 6 35
ASE_00411 0.37 0.34 0.40 30 49380 50 5 40 5 59
ASE_00412 0.43 0.38 0.48 40 58228 43 5 38 0 65
ASE_00413 0.60 0.58 0.62 47 44475 35 8 21 6 34
ASE_00414 0.33 0.29 0.37 28 46284 54 4 44 6 67
ASE_00415 0.39 0.34 0.45 35 54868 46 0 43 3 68
ASE_00416 0.40 0.35 0.45 45 77321 55 2 53 0 82
ASE_00417 0.46 0.44 0.47 44 54522 50 3 46 1 56
ASE_00418 0.29 0.27 0.32 20 38719 44 0 42 2 55
ASE_00419 0.65 0.60 0.70 62 54858 27 3 23 1 41
ASE_00422 0.71 0.64 0.79 60 46895 21 1 15 5 34
ASE_00423 0.61 0.56 0.66 61 56860 32 6 26 0 48
ASE_00426 0.34 0.31 0.38 33 60988 54 5 49 0 75
ASE_00428 0.26 0.23 0.29 29 76537 70 2 68 0 96
ASE_00430 0.75 0.67 0.83 65 46893 18 1 12 5 32
ASE_00431 0.31 0.26 0.37 25 46292 43 6 37 0 70
ASE_00434 0.36 0.34 0.38 37 68167 64 11 50 3 73
ASE_00437 0.40 0.34 0.46 46 79302 53 2 51 0 89
ASE_00438 0.39 0.34 0.46 39 65982 45 0 45 0 77
ASE_00441 0.36 0.32 0.41 36 64173 52 0 52 0 76
ASE_00447 0.35 0.29 0.43 34 60298 47 1 45 1 82
ASE_00448 0.28 0.26 0.30 29 64164 68 6 62 0 83
ASE_00451 0.38 0.34 0.43 42 70778 56 3 53 0 83
CRW_00016 0.53 0.46 0.61 55 77331 44 4 31 9 65
CRW_00610 0.40 0.36 0.46 29 36252 37 5 29 3 52
CRW_00613 0.48 0.42 0.54 33 34919 34 2 26 6 45
CRW_00618 0.33 0.31 0.35 19 56225 57 6 30 21 42
CRW_00633 0.38 0.35 0.42 37 63457 52 6 46 0 69
CRW_00634 0.29 0.28 0.30 26 64533 68 8 53 7 68
CRW_00670 0.37 0.34 0.41 41 70025 60 3 56 1 79
CRW_00671 0.55 0.50 0.60 59 62736 40 2 38 0 58
CRW_00672 0.30 0.29 0.32 32 72291 71 14 53 4 79
CRW_00674 0.29 0.26 0.33 32 83339 67 8 57 2 92
CRW_00676 0.34 0.34 0.34 39 93413 80 20 56 4 76
CRW_00692 0.26 0.24 0.28 22 68555 62 20 38 4 68
PDB_00827 0.65 0.54 0.79 44 26972 13 0 12 1 37
PDB_00919 0.29 0.24 0.36 25 44183 45 2 43 0 78
RFA_00597 0.15 0.15 0.15 16 97796 96 11 80 5 93
RFA_00598 0.14 0.13 0.14 13 84576 88 14 63 11 88
RFA_00601 0.10 0.11 0.11 12 99122 105 21 80 4 102
TMR_00173 0.32 0.33 0.32 14 42151 66 10 20 36 28
TMR_00357 0.24 0.22 0.26 20 82950 75 7 51 17 72
TMR_00601 0.25 0.24 0.26 10 58957 74 7 22 45 32
TMR_00696 0.05 0.04 0.05 5 84980 104 5 88 11 109

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.