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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidHomfold‑LAST - scored higher in this pairwise comparison

  4. Performance of TurboFold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidHomfold‑LAST & TurboFold(seed) [.zip] - may take several seconds...


Overview

Metric CentroidHomfold‑LAST TurboFold(seed)
MCC 0.789 > 0.710
Average MCC ± 95% Confidence Intervals 0.789 ± > 0.710 ±
Sensitivity 0.692 > 0.677
Positive Predictive Value 0.900 > 0.746
Total TP 45 > 44
Total TN 27211 > 27202
Total FP 5 < 16
Total FP CONTRA 0 < 4
Total FP INCONS 5 < 11
Total FP COMP 0 < 1
Total FN 20 < 21
P-value 0.0

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Performance plots


  1. Comparison of performance of CentroidHomfold-LAST and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidHomfold‑LAST and TurboFold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidHomfold-LAST and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidHomfold‑LAST and TurboFold(seed)).

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Performance of CentroidHomfold‑LAST - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidHomfold‑LAST

Total Base Pair Counts
Total TP 45
Total TN 27211
Total FP 5
Total FP CONTRA 0
Total FP INCONS 5
Total FP COMP 0
Total FN 20
Total Scores
MCC 0.789
Average MCC ± 95% Confidence Intervals 0.789 ±
Sensitivity 0.692
Positive Predictive Value 0.900
Nr of predictions 1

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2. Individual counts for CentroidHomfold‑LAST [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00210 0.79 0.69 0.90 45 27211 5 0 5 0 20

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Performance of TurboFold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 44
Total TN 27202
Total FP 16
Total FP CONTRA 4
Total FP INCONS 11
Total FP COMP 1
Total FN 21
Total Scores
MCC 0.710
Average MCC ± 95% Confidence Intervals 0.710 ±
Sensitivity 0.677
Positive Predictive Value 0.746
Nr of predictions 1

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00210 0.71 0.68 0.75 44 27202 16 4 11 1 21

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.