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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Cylofold - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for Cylofold & NanoFolder [.zip] - may take several seconds...


Overview

Metric Cylofold NanoFolder
MCC 0.378 > 0.076
Average MCC ± 95% Confidence Intervals 0.378 ± > 0.076 ±
Sensitivity 0.333 > 0.091
Positive Predictive Value 0.431 > 0.067
Total TP 22 > 6
Total TN 28152 > 28114
Total FP 33 < 84
Total FP CONTRA 0 < 14
Total FP INCONS 29 < 69
Total FP COMP 4 > 1
Total FN 44 < 60
P-value 0.0

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Performance plots


  1. Comparison of performance of Cylofold and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Cylofold and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Cylofold and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Cylofold and NanoFolder).

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Performance of Cylofold - scored higher in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 22
Total TN 28152
Total FP 33
Total FP CONTRA 0
Total FP INCONS 29
Total FP COMP 4
Total FN 44
Total Scores
MCC 0.378
Average MCC ± 95% Confidence Intervals 0.378 ±
Sensitivity 0.333
Positive Predictive Value 0.431
Nr of predictions 1

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00429 - 0.38 0.33 0.43 22 28152 33 0 29 4 44

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 6
Total TN 28114
Total FP 84
Total FP CONTRA 14
Total FP INCONS 69
Total FP COMP 1
Total FN 60
Total Scores
MCC 0.076
Average MCC ± 95% Confidence Intervals 0.076 ±
Sensitivity 0.091
Positive Predictive Value 0.067
Nr of predictions 1

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00429 - 0.08 0.09 0.07 6 28114 84 14 69 1 60

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.