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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Cylofold - scored higher in this pairwise comparison

  4. Performance of Vsfold4 - scored lower in this pairwise comparison

  5. Compile and download dataset for Cylofold & Vsfold4 [.zip] - may take several seconds...


Overview

Metric Cylofold Vsfold4
MCC 0.271 > 0.267
Average MCC ± 95% Confidence Intervals 0.275 ± 1.303 > 0.267 ± 0.489
Sensitivity 0.241 = 0.241
Positive Predictive Value 0.308 > 0.300
Total TP 33 = 33
Total TN 60481 > 60478
Total FP 78 < 82
Total FP CONTRA 3 < 5
Total FP INCONS 71 < 72
Total FP COMP 4 < 5
Total FN 104 = 104
P-value 0.0

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Performance plots


  1. Comparison of performance of Cylofold and Vsfold4. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Cylofold and Vsfold4).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Cylofold and Vsfold4. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Cylofold and Vsfold4).

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Performance of Cylofold - scored higher in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 33
Total TN 60481
Total FP 78
Total FP CONTRA 3
Total FP INCONS 71
Total FP COMP 4
Total FN 104
Total Scores
MCC 0.271
Average MCC ± 95% Confidence Intervals 0.275 ± 1.303
Sensitivity 0.241
Positive Predictive Value 0.308
Nr of predictions 2

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00408 - 0.17 0.15 0.20 11 32329 45 3 42 0 60
ASE_00429 - 0.38 0.33 0.43 22 28152 33 0 29 4 44

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Performance of Vsfold4 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold4

Total Base Pair Counts
Total TP 33
Total TN 60478
Total FP 82
Total FP CONTRA 5
Total FP INCONS 72
Total FP COMP 5
Total FN 104
Total Scores
MCC 0.267
Average MCC ± 95% Confidence Intervals 0.267 ± 0.489
Sensitivity 0.241
Positive Predictive Value 0.300
Nr of predictions 2

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2. Individual counts for Vsfold4 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00408 - 0.31 0.27 0.35 19 32331 35 1 34 0 52
ASE_00429 - 0.23 0.21 0.25 14 28147 47 4 38 5 52

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.