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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(seed) - scored higher in this pairwise comparison

  4. Performance of RNASampler(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(seed) & RNASampler(20) [.zip] - may take several seconds...


Overview

Metric MXScarna(seed) RNASampler(20)
MCC 0.574 > 0.480
Average MCC ± 95% Confidence Intervals 0.571 ± 0.152 > 0.474 ± 0.098
Sensitivity 0.455 > 0.343
Positive Predictive Value 0.725 > 0.673
Total TP 374 > 282
Total TN 482380 < 482477
Total FP 185 > 163
Total FP CONTRA 19 > 16
Total FP INCONS 123 > 121
Total FP COMP 43 > 26
Total FN 448 < 540
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(seed) and RNASampler(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(seed) and RNASampler(20)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for MXScarna(seed) and RNASampler(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(seed) and RNASampler(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(seed) and RNASampler(20)).

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Performance of MXScarna(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(seed)

Total Base Pair Counts
Total TP 374
Total TN 482380
Total FP 185
Total FP CONTRA 19
Total FP INCONS 123
Total FP COMP 43
Total FN 448
Total Scores
MCC 0.574
Average MCC ± 95% Confidence Intervals 0.571 ± 0.152
Sensitivity 0.455
Positive Predictive Value 0.725
Nr of predictions 8

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2. Individual counts for MXScarna(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00064 0.82 0.71 0.94 63 45384 7 1 3 3 26
ASE_00090 0.66 0.54 0.81 55 55543 16 2 11 3 46
ASE_00135 0.40 0.32 0.51 35 63121 35 4 30 1 74
ASE_00153 0.60 0.48 0.76 35 57584 26 0 11 15 38
ASE_00215 0.38 0.26 0.54 26 48468 23 2 20 1 73
ASE_00328 0.73 0.66 0.80 74 72679 31 5 13 13 38
ASE_00361 0.66 0.46 0.94 59 75403 7 1 3 3 68
ASE_00441 0.32 0.24 0.43 27 64198 40 4 32 4 85

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Performance of RNASampler(20) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 282
Total TN 482477
Total FP 163
Total FP CONTRA 16
Total FP INCONS 121
Total FP COMP 26
Total FN 540
Total Scores
MCC 0.480
Average MCC ± 95% Confidence Intervals 0.474 ± 0.098
Sensitivity 0.343
Positive Predictive Value 0.673
Nr of predictions 8

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2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00064 0.44 0.34 0.58 30 45399 23 1 21 1 59
ASE_00090 0.54 0.40 0.74 40 55557 14 0 14 0 61
ASE_00135 0.54 0.36 0.83 39 63143 16 0 8 8 70
ASE_00153 0.38 0.33 0.44 24 57576 38 7 23 8 49
ASE_00215 0.38 0.23 0.62 23 48479 16 0 14 2 76
ASE_00328 0.70 0.57 0.85 64 72696 14 5 6 3 48
ASE_00361 0.34 0.21 0.55 27 75417 26 3 19 4 100
ASE_00441 0.46 0.31 0.69 35 64210 16 0 16 0 77

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.