CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(20) - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(20) & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric Murlet(20) Mastr(seed)
MCC 0.537 > 0.000
Average MCC ± 95% Confidence Intervals 0.538 ± 0.026 > 0.000 ± 0.000
Sensitivity 0.394 > 0.000
Positive Predictive Value 0.734 > 0.000
Total TP 3977 > 0
Total TN 5725382 < 5730798
Total FP 1551 > 0
Total FP CONTRA 134 > 0
Total FP INCONS 1305 > 0
Total FP COMP 112 > 0
Total FN 6126 < 10103
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of Murlet(20) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(20) and Mastr(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Murlet(20) and Mastr(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(20) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(20) and Mastr(seed)).

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Performance of Murlet(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 3977
Total TN 5725382
Total FP 1551
Total FP CONTRA 134
Total FP INCONS 1305
Total FP COMP 112
Total FN 6126
Total Scores
MCC 0.537
Average MCC ± 95% Confidence Intervals 0.538 ± 0.026
Sensitivity 0.394
Positive Predictive Value 0.734
Nr of predictions 96

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2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.46 0.34 0.61 33 47841 21 1 20 0 64
ASE_00018 0.61 0.45 0.82 60 80528 13 3 10 0 74
ASE_00022 0.67 0.50 0.89 62 82958 15 0 8 7 62
ASE_00028 0.56 0.40 0.77 51 84600 15 5 10 0 75
ASE_00035 0.62 0.49 0.79 58 70427 17 4 11 2 60
ASE_00064 0.55 0.39 0.76 35 45405 14 3 8 3 54
ASE_00068 0.62 0.42 0.90 36 37635 4 3 1 0 49
ASE_00077 0.48 0.35 0.67 30 45105 18 0 15 3 56
ASE_00078 0.64 0.53 0.79 44 43015 12 3 9 0 39
ASE_00081 0.73 0.58 0.93 56 49710 5 0 4 1 41
ASE_00082 0.27 0.20 0.37 23 70438 42 2 37 3 93
ASE_00084 0.53 0.36 0.77 36 53581 12 0 11 1 63
ASE_00092 0.58 0.40 0.85 45 63493 10 0 8 2 68
ASE_00104 0.51 0.38 0.69 45 64196 20 1 19 0 74
ASE_00119 0.11 0.08 0.16 9 62779 48 2 45 1 99
ASE_00123 0.55 0.40 0.76 34 38458 11 0 11 0 51
ASE_00135 0.34 0.24 0.49 26 63137 29 3 24 2 83
ASE_00138 0.60 0.47 0.76 38 40420 13 0 12 1 43
ASE_00142 0.52 0.40 0.68 49 67089 23 1 22 0 73
ASE_00146 0.70 0.56 0.87 69 70797 13 0 10 3 55
ASE_00153 0.34 0.23 0.50 17 57596 26 3 14 9 56
ASE_00170 0.52 0.37 0.74 34 48782 12 0 12 0 59
ASE_00179 0.49 0.40 0.61 34 44197 22 0 22 0 50
ASE_00180 0.70 0.55 0.90 55 51299 6 2 4 0 45
ASE_00182 0.24 0.15 0.41 20 84206 31 1 28 2 116
ASE_00184 0.58 0.42 0.80 43 54561 11 2 9 0 59
ASE_00185 0.28 0.16 0.48 21 73492 23 0 23 0 107
ASE_00186 0.61 0.45 0.84 59 78933 11 1 10 0 73
ASE_00190 0.38 0.22 0.67 20 45421 12 0 10 2 70
ASE_00212 0.55 0.39 0.78 58 93887 16 1 15 0 90
ASE_00214 0.40 0.27 0.58 28 56232 21 1 19 1 75
ASE_00215 0.46 0.31 0.69 31 48471 14 4 10 0 68
ASE_00217 0.66 0.50 0.87 45 40418 7 1 6 0 45
ASE_00221 0.58 0.44 0.78 51 64555 14 0 14 0 66
ASE_00228 0.53 0.44 0.63 38 46911 23 1 21 1 48
ASE_00229 0.61 0.48 0.76 42 42431 13 3 10 0 45
ASE_00238 0.45 0.30 0.68 34 64211 16 2 14 0 80
ASE_00241 0.66 0.55 0.79 48 43895 16 2 11 3 39
ASE_00248 0.76 0.63 0.91 72 62402 7 0 7 0 42
ASE_00255 0.53 0.39 0.72 51 74620 21 1 19 1 79
ASE_00257 0.55 0.43 0.69 42 50979 19 0 19 0 55
ASE_00267 0.76 0.61 0.95 54 45093 4 2 1 1 34
ASE_00270 0.21 0.14 0.32 18 72333 41 0 39 2 110
ASE_00279 0.63 0.48 0.84 48 53244 9 1 8 0 53
ASE_00280 0.67 0.54 0.84 53 51940 10 3 7 0 45
ASE_00281 0.74 0.60 0.91 53 44493 5 0 5 0 35
ASE_00283 0.55 0.41 0.73 44 61716 16 0 16 0 63
ASE_00285 0.45 0.33 0.62 40 68941 25 1 24 0 82
ASE_00292 0.52 0.36 0.74 50 81742 18 1 17 0 88
ASE_00294 0.55 0.37 0.83 63 114405 14 4 9 1 108
ASE_00297 0.59 0.41 0.85 40 52928 10 0 7 3 58
ASE_00298 0.22 0.15 0.32 17 67475 36 4 32 0 96
ASE_00318 0.66 0.49 0.89 58 80135 16 2 5 9 60
ASE_00328 0.59 0.48 0.72 54 72696 27 5 16 6 58
ASE_00332 0.63 0.47 0.83 65 81732 13 2 11 0 73
ASE_00335 0.60 0.48 0.76 56 75392 19 5 13 1 60
ASE_00340 0.45 0.34 0.60 29 46008 22 3 16 3 56
ASE_00353 0.50 0.35 0.71 37 57918 15 0 15 0 70
ASE_00361 0.57 0.39 0.82 50 75405 11 1 10 0 77
ASE_00362 0.56 0.38 0.81 35 48162 12 0 8 4 56
ASE_00363 0.61 0.44 0.85 41 51312 7 0 7 0 53
ASE_00364 0.58 0.38 0.89 40 54240 5 0 5 0 65
ASE_00366 0.49 0.36 0.67 35 58601 19 0 17 2 63
ASE_00367 0.71 0.57 0.89 49 43016 6 2 4 0 37
ASE_00372 0.40 0.31 0.53 31 51944 28 3 25 0 69
ASE_00376 0.57 0.40 0.82 42 56902 9 2 7 0 63
ASE_00382 0.65 0.51 0.83 43 41853 9 2 7 0 41
ASE_00384 0.59 0.43 0.80 40 48466 10 2 8 0 52
ASE_00386 0.54 0.36 0.80 35 50359 9 1 8 0 61
ASE_00387 0.64 0.45 0.90 47 55893 5 0 5 0 57
ASE_00388 0.53 0.38 0.72 34 45706 16 1 12 3 55
ASE_00390 0.77 0.64 0.93 54 42137 6 1 3 2 31
ASE_00393 0.55 0.41 0.73 38 47843 15 3 11 1 55
ASE_00394 0.56 0.41 0.78 38 46922 11 1 10 0 55
ASE_00395 0.68 0.51 0.90 43 41568 5 0 5 0 41
ASE_00396 0.62 0.47 0.81 39 41568 9 0 9 0 44
ASE_00397 0.63 0.45 0.89 47 54562 9 1 5 3 58
ASE_00398 0.49 0.32 0.75 33 55901 12 0 11 1 71
ASE_00400 0.47 0.36 0.61 38 57908 25 3 21 1 68
ASE_00402 0.55 0.35 0.86 30 42451 5 2 3 0 55
ASE_00404 0.72 0.55 0.94 47 43021 4 0 3 1 38
ASE_00406 0.60 0.44 0.84 41 48779 8 0 8 0 53
ASE_00411 0.59 0.39 0.88 35 49415 5 0 5 0 54
ASE_00412 0.51 0.32 0.79 34 58268 11 0 9 2 71
ASE_00416 0.45 0.33 0.62 42 77353 26 1 25 0 85
ASE_00419 0.49 0.33 0.74 34 54900 12 2 10 0 69
ASE_00422 0.50 0.35 0.70 33 46924 14 0 14 0 61
ASE_00423 0.65 0.53 0.79 58 56880 15 0 15 0 51
ASE_00428 0.47 0.34 0.67 42 76573 21 4 17 0 83
ASE_00430 0.50 0.37 0.68 36 46918 17 0 17 0 61
ASE_00437 0.42 0.32 0.56 43 79324 34 3 31 0 92
ASE_00448 0.63 0.49 0.82 55 64194 12 3 9 0 57
ASE_00451 0.56 0.41 0.76 51 70809 16 1 15 0 74
RFA_00599 0.44 0.34 0.58 38 101409 33 1 27 5 73
RFA_00601 0.31 0.23 0.42 26 99173 43 3 33 7 88
RFA_00602 0.24 0.16 0.35 19 101421 41 2 33 6 97

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 5730798
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 10103
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 96

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.00 0.00 0.00 0 47895 0 0 0 0 97
ASE_00018 0.00 0.00 0.00 0 80601 0 0 0 0 134
ASE_00022 0.00 0.00 0.00 0 83028 0 0 0 0 124
ASE_00028 0.00 0.00 0.00 0 84666 0 0 0 0 126
ASE_00035 0.00 0.00 0.00 0 70500 0 0 0 0 118
ASE_00064 0.00 0.00 0.00 0 45451 0 0 0 0 89
ASE_00068 0.00 0.00 0.00 0 37675 0 0 0 0 85
ASE_00077 0.00 0.00 0.00 0 45150 0 0 0 0 86
ASE_00078 0.00 0.00 0.00 0 43071 0 0 0 0 83
ASE_00081 0.00 0.00 0.00 0 49770 0 0 0 0 97
ASE_00082 0.00 0.00 0.00 0 70500 0 0 0 0 116
ASE_00084 0.00 0.00 0.00 0 53628 0 0 0 0 99
ASE_00092 0.00 0.00 0.00 0 63546 0 0 0 0 113
ASE_00104 0.00 0.00 0.00 0 64261 0 0 0 0 119
ASE_00119 0.00 0.00 0.00 0 62835 0 0 0 0 108
ASE_00123 0.00 0.00 0.00 0 38503 0 0 0 0 85
ASE_00135 0.00 0.00 0.00 0 63190 0 0 0 0 109
ASE_00138 0.00 0.00 0.00 0 40470 0 0 0 0 81
ASE_00142 0.00 0.00 0.00 0 67161 0 0 0 0 122
ASE_00146 0.00 0.00 0.00 0 70876 0 0 0 0 124
ASE_00153 0.00 0.00 0.00 0 57630 0 0 0 0 73
ASE_00170 0.00 0.00 0.00 0 48828 0 0 0 0 93
ASE_00179 0.00 0.00 0.00 0 44253 0 0 0 0 84
ASE_00180 0.00 0.00 0.00 0 51360 0 0 0 0 100
ASE_00182 0.00 0.00 0.00 0 84255 0 0 0 0 136
ASE_00184 0.00 0.00 0.00 0 54615 0 0 0 0 102
ASE_00185 0.00 0.00 0.00 0 73536 0 0 0 0 128
ASE_00186 0.00 0.00 0.00 0 79003 0 0 0 0 132
ASE_00190 0.00 0.00 0.00 0 45451 0 0 0 0 90
ASE_00212 0.00 0.00 0.00 0 93961 0 0 0 0 148
ASE_00214 0.00 0.00 0.00 0 56280 0 0 0 0 103
ASE_00215 0.00 0.00 0.00 0 48516 0 0 0 0 99
ASE_00217 0.00 0.00 0.00 0 40470 0 0 0 0 90
ASE_00221 0.00 0.00 0.00 0 64620 0 0 0 0 117
ASE_00228 0.00 0.00 0.00 0 46971 0 0 0 0 86
ASE_00229 0.00 0.00 0.00 0 42486 0 0 0 0 87
ASE_00238 0.00 0.00 0.00 0 64261 0 0 0 0 114
ASE_00241 0.00 0.00 0.00 0 43956 0 0 0 0 87
ASE_00248 0.00 0.00 0.00 0 62481 0 0 0 0 114
ASE_00255 0.00 0.00 0.00 0 74691 0 0 0 0 130
ASE_00257 0.00 0.00 0.00 0 51040 0 0 0 0 97
ASE_00267 0.00 0.00 0.00 0 45150 0 0 0 0 88
ASE_00270 0.00 0.00 0.00 0 72390 0 0 0 0 128
ASE_00279 0.00 0.00 0.00 0 53301 0 0 0 0 101
ASE_00280 0.00 0.00 0.00 0 52003 0 0 0 0 98
ASE_00281 0.00 0.00 0.00 0 44551 0 0 0 0 88
ASE_00283 0.00 0.00 0.00 0 61776 0 0 0 0 107
ASE_00285 0.00 0.00 0.00 0 69006 0 0 0 0 122
ASE_00292 0.00 0.00 0.00 0 81810 0 0 0 0 138
ASE_00294 0.00 0.00 0.00 0 114481 0 0 0 0 171
ASE_00297 0.00 0.00 0.00 0 52975 0 0 0 0 98
ASE_00298 0.00 0.00 0.00 0 67528 0 0 0 0 113
ASE_00318 0.00 0.00 0.00 0 80200 0 0 0 0 118
ASE_00328 0.00 0.00 0.00 0 72771 0 0 0 0 112
ASE_00332 0.00 0.00 0.00 0 81810 0 0 0 0 138
ASE_00335 0.00 0.00 0.00 0 75466 0 0 0 0 116
ASE_00340 0.00 0.00 0.00 0 46056 0 0 0 0 85
ASE_00353 0.00 0.00 0.00 0 57970 0 0 0 0 107
ASE_00361 0.00 0.00 0.00 0 75466 0 0 0 0 127
ASE_00362 0.00 0.00 0.00 0 48205 0 0 0 0 91
ASE_00363 0.00 0.00 0.00 0 51360 0 0 0 0 94
ASE_00364 0.00 0.00 0.00 0 54285 0 0 0 0 105
ASE_00366 0.00 0.00 0.00 0 58653 0 0 0 0 98
ASE_00367 0.00 0.00 0.00 0 43071 0 0 0 0 86
ASE_00372 0.00 0.00 0.00 0 52003 0 0 0 0 100
ASE_00376 0.00 0.00 0.00 0 56953 0 0 0 0 105
ASE_00382 0.00 0.00 0.00 0 41905 0 0 0 0 84
ASE_00384 0.00 0.00 0.00 0 48516 0 0 0 0 92
ASE_00386 0.00 0.00 0.00 0 50403 0 0 0 0 96
ASE_00387 0.00 0.00 0.00 0 55945 0 0 0 0 104
ASE_00388 0.00 0.00 0.00 0 45753 0 0 0 0 89
ASE_00390 0.00 0.00 0.00 0 42195 0 0 0 0 85
ASE_00393 0.00 0.00 0.00 0 47895 0 0 0 0 93
ASE_00394 0.00 0.00 0.00 0 46971 0 0 0 0 93
ASE_00395 0.00 0.00 0.00 0 41616 0 0 0 0 84
ASE_00396 0.00 0.00 0.00 0 41616 0 0 0 0 83
ASE_00397 0.00 0.00 0.00 0 54615 0 0 0 0 105
ASE_00398 0.00 0.00 0.00 0 55945 0 0 0 0 104
ASE_00400 0.00 0.00 0.00 0 57970 0 0 0 0 106
ASE_00402 0.00 0.00 0.00 0 42486 0 0 0 0 85
ASE_00404 0.00 0.00 0.00 0 43071 0 0 0 0 85
ASE_00406 0.00 0.00 0.00 0 48828 0 0 0 0 94
ASE_00411 0.00 0.00 0.00 0 49455 0 0 0 0 89
ASE_00412 0.00 0.00 0.00 0 58311 0 0 0 0 105
ASE_00416 0.00 0.00 0.00 0 77421 0 0 0 0 127
ASE_00419 0.00 0.00 0.00 0 54946 0 0 0 0 103
ASE_00422 0.00 0.00 0.00 0 46971 0 0 0 0 94
ASE_00423 0.00 0.00 0.00 0 56953 0 0 0 0 109
ASE_00428 0.00 0.00 0.00 0 76636 0 0 0 0 125
ASE_00430 0.00 0.00 0.00 0 46971 0 0 0 0 97
ASE_00437 0.00 0.00 0.00 0 79401 0 0 0 0 135
ASE_00448 0.00 0.00 0.00 0 64261 0 0 0 0 112
ASE_00451 0.00 0.00 0.00 0 70876 0 0 0 0 125
RFA_00599 0.00 0.00 0.00 0 101475 0 0 0 0 111
RFA_00601 0.00 0.00 0.00 0 99235 0 0 0 0 114
RFA_00602 0.00 0.00 0.00 0 101475 0 0 0 0 116

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.