CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(20) - scored higher in this pairwise comparison

  4. Performance of RSpredict(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(20) & RSpredict(seed) [.zip] - may take several seconds...


Overview

Metric Murlet(20) RSpredict(seed)
MCC 0.533 > 0.059
Average MCC ± 95% Confidence Intervals 0.534 ± 0.025 > 0.042 ± 0.015
Sensitivity 0.389 > 0.015
Positive Predictive Value 0.732 > 0.233
Total TP 4397 > 174
Total TN 6436955 < 6442217
Total FP 1732 > 646
Total FP CONTRA 147 > 33
Total FP INCONS 1464 > 539
Total FP COMP 121 > 74
Total FN 6918 < 11141
P-value 3.56938820447e-08

^top




Performance plots


  1. Comparison of performance of Murlet(20) and RSpredict(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(20) and RSpredict(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Murlet(20) and RSpredict(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(20) and RSpredict(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(20) and RSpredict(seed)).

^top





Performance of Murlet(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 4397
Total TN 6436955
Total FP 1732
Total FP CONTRA 147
Total FP INCONS 1464
Total FP COMP 121
Total FN 6918
Total Scores
MCC 0.533
Average MCC ± 95% Confidence Intervals 0.534 ± 0.025
Sensitivity 0.389
Positive Predictive Value 0.732
Nr of predictions 106

^top



2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.46 0.34 0.61 33 47841 21 1 20 0 64
ASE_00007 0.71 0.57 0.89 63 59614 8 2 6 0 47
ASE_00018 0.61 0.45 0.82 60 80528 13 3 10 0 74
ASE_00022 0.67 0.50 0.89 62 82958 15 0 8 7 62
ASE_00028 0.56 0.40 0.77 51 84600 15 5 10 0 75
ASE_00035 0.62 0.49 0.79 58 70427 17 4 11 2 60
ASE_00040 0.62 0.43 0.90 57 78940 6 0 6 0 76
ASE_00064 0.55 0.39 0.76 35 45405 14 3 8 3 54
ASE_00068 0.62 0.42 0.90 36 37635 4 3 1 0 49
ASE_00075 0.51 0.34 0.76 55 108739 19 1 16 2 107
ASE_00077 0.48 0.35 0.67 30 45105 18 0 15 3 56
ASE_00078 0.64 0.53 0.79 44 43015 12 3 9 0 39
ASE_00080 0.31 0.21 0.46 26 71574 31 3 28 0 97
ASE_00081 0.73 0.58 0.93 56 49710 5 0 4 1 41
ASE_00082 0.27 0.20 0.37 23 70438 42 2 37 3 93
ASE_00083 0.54 0.39 0.75 43 62424 14 2 12 0 67
ASE_00084 0.53 0.36 0.77 36 53581 12 0 11 1 63
ASE_00087 0.35 0.21 0.58 30 88358 22 0 22 0 114
ASE_00092 0.58 0.40 0.85 45 63493 10 0 8 2 68
ASE_00104 0.51 0.38 0.69 45 64196 20 1 19 0 74
ASE_00107 0.64 0.48 0.86 61 73082 13 2 8 3 66
ASE_00115 0.46 0.30 0.71 30 54573 12 1 11 0 71
ASE_00119 0.11 0.08 0.16 9 62779 48 2 45 1 99
ASE_00123 0.55 0.40 0.76 34 38458 11 0 11 0 51
ASE_00135 0.34 0.24 0.49 26 63137 29 3 24 2 83
ASE_00138 0.60 0.47 0.76 38 40420 13 0 12 1 43
ASE_00142 0.52 0.40 0.68 49 67089 23 1 22 0 73
ASE_00146 0.70 0.56 0.87 69 70797 13 0 10 3 55
ASE_00153 0.34 0.23 0.50 17 57596 26 3 14 9 56
ASE_00163 0.47 0.32 0.70 30 53258 13 0 13 0 63
ASE_00170 0.52 0.37 0.74 34 48782 12 0 12 0 59
ASE_00174 0.30 0.23 0.39 25 61011 43 2 37 4 84
ASE_00179 0.49 0.40 0.61 34 44197 22 0 22 0 50
ASE_00180 0.70 0.55 0.90 55 51299 6 2 4 0 45
ASE_00182 0.24 0.15 0.41 20 84206 31 1 28 2 116
ASE_00184 0.58 0.42 0.80 43 54561 11 2 9 0 59
ASE_00185 0.28 0.16 0.48 21 73492 23 0 23 0 107
ASE_00186 0.61 0.45 0.84 59 78933 11 1 10 0 73
ASE_00190 0.38 0.22 0.67 20 45421 12 0 10 2 70
ASE_00212 0.55 0.39 0.78 58 93887 16 1 15 0 90
ASE_00214 0.40 0.27 0.58 28 56232 21 1 19 1 75
ASE_00215 0.46 0.31 0.69 31 48471 14 4 10 0 68
ASE_00217 0.66 0.50 0.87 45 40418 7 1 6 0 45
ASE_00221 0.58 0.44 0.78 51 64555 14 0 14 0 66
ASE_00228 0.53 0.44 0.63 38 46911 23 1 21 1 48
ASE_00229 0.61 0.48 0.76 42 42431 13 3 10 0 45
ASE_00238 0.45 0.30 0.68 34 64211 16 2 14 0 80
ASE_00241 0.66 0.55 0.79 48 43895 16 2 11 3 39
ASE_00248 0.76 0.63 0.91 72 62402 7 0 7 0 42
ASE_00255 0.53 0.39 0.72 51 74620 21 1 19 1 79
ASE_00257 0.55 0.43 0.69 42 50979 19 0 19 0 55
ASE_00267 0.76 0.61 0.95 54 45093 4 2 1 1 34
ASE_00270 0.21 0.14 0.32 18 72333 41 0 39 2 110
ASE_00279 0.63 0.48 0.84 48 53244 9 1 8 0 53
ASE_00280 0.67 0.54 0.84 53 51940 10 3 7 0 45
ASE_00281 0.74 0.60 0.91 53 44493 5 0 5 0 35
ASE_00283 0.55 0.41 0.73 44 61716 16 0 16 0 63
ASE_00285 0.45 0.33 0.62 40 68941 25 1 24 0 82
ASE_00292 0.52 0.36 0.74 50 81742 18 1 17 0 88
ASE_00294 0.55 0.37 0.83 63 114405 14 4 9 1 108
ASE_00297 0.59 0.41 0.85 40 52928 10 0 7 3 58
ASE_00298 0.22 0.15 0.32 17 67475 36 4 32 0 96
ASE_00318 0.66 0.49 0.89 58 80135 16 2 5 9 60
ASE_00328 0.59 0.48 0.72 54 72696 27 5 16 6 58
ASE_00332 0.63 0.47 0.83 65 81732 13 2 11 0 73
ASE_00335 0.60 0.48 0.76 56 75392 19 5 13 1 60
ASE_00340 0.45 0.34 0.60 29 46008 22 3 16 3 56
ASE_00353 0.50 0.35 0.71 37 57918 15 0 15 0 70
ASE_00361 0.57 0.39 0.82 50 75405 11 1 10 0 77
ASE_00362 0.56 0.38 0.81 35 48162 12 0 8 4 56
ASE_00363 0.61 0.44 0.85 41 51312 7 0 7 0 53
ASE_00364 0.58 0.38 0.89 40 54240 5 0 5 0 65
ASE_00366 0.49 0.36 0.67 35 58601 19 0 17 2 63
ASE_00367 0.71 0.57 0.89 49 43016 6 2 4 0 37
ASE_00372 0.40 0.31 0.53 31 51944 28 3 25 0 69
ASE_00376 0.57 0.40 0.82 42 56902 9 2 7 0 63
ASE_00382 0.65 0.51 0.83 43 41853 9 2 7 0 41
ASE_00384 0.59 0.43 0.80 40 48466 10 2 8 0 52
ASE_00386 0.54 0.36 0.80 35 50359 9 1 8 0 61
ASE_00387 0.64 0.45 0.90 47 55893 5 0 5 0 57
ASE_00388 0.53 0.38 0.72 34 45706 16 1 12 3 55
ASE_00390 0.77 0.64 0.93 54 42137 6 1 3 2 31
ASE_00393 0.55 0.41 0.73 38 47843 15 3 11 1 55
ASE_00394 0.56 0.41 0.78 38 46922 11 1 10 0 55
ASE_00395 0.68 0.51 0.90 43 41568 5 0 5 0 41
ASE_00396 0.62 0.47 0.81 39 41568 9 0 9 0 44
ASE_00397 0.63 0.45 0.89 47 54562 9 1 5 3 58
ASE_00398 0.49 0.32 0.75 33 55901 12 0 11 1 71
ASE_00400 0.47 0.36 0.61 38 57908 25 3 21 1 68
ASE_00402 0.55 0.35 0.86 30 42451 5 2 3 0 55
ASE_00404 0.72 0.55 0.94 47 43021 4 0 3 1 38
ASE_00406 0.60 0.44 0.84 41 48779 8 0 8 0 53
ASE_00411 0.59 0.39 0.88 35 49415 5 0 5 0 54
ASE_00412 0.51 0.32 0.79 34 58268 11 0 9 2 71
ASE_00416 0.45 0.33 0.62 42 77353 26 1 25 0 85
ASE_00419 0.49 0.33 0.74 34 54900 12 2 10 0 69
ASE_00422 0.50 0.35 0.70 33 46924 14 0 14 0 61
ASE_00423 0.65 0.53 0.79 58 56880 15 0 15 0 51
ASE_00428 0.47 0.34 0.67 42 76573 21 4 17 0 83
ASE_00430 0.50 0.37 0.68 36 46918 17 0 17 0 61
ASE_00437 0.42 0.32 0.56 43 79324 34 3 31 0 92
ASE_00448 0.63 0.49 0.82 55 64194 12 3 9 0 57
ASE_00451 0.56 0.41 0.76 51 70809 16 1 15 0 74
RFA_00599 0.44 0.34 0.58 38 101409 33 1 27 5 73
RFA_00601 0.31 0.23 0.42 26 99173 43 3 33 7 88
RFA_00602 0.24 0.16 0.35 19 101421 41 2 33 6 97

^top



Performance of RSpredict(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(seed)

Total Base Pair Counts
Total TP 174
Total TN 6442217
Total FP 646
Total FP CONTRA 33
Total FP INCONS 539
Total FP COMP 74
Total FN 11141
Total Scores
MCC 0.059
Average MCC ± 95% Confidence Intervals 0.042 ± 0.015
Sensitivity 0.015
Positive Predictive Value 0.233
Nr of predictions 106

^top



2. Individual counts for RSpredict(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00004 0.00 0.00 0.00 0 47894 2 0 1 1 97
ASE_00007 0.16 0.05 0.56 5 59676 4 0 4 0 105
ASE_00018 0.13 0.04 0.35 6 80584 11 0 11 0 128
ASE_00022 0.00 0.00 0.00 0 83008 21 3 17 1 124
ASE_00028 0.02 0.01 0.05 1 84646 22 5 14 3 125
ASE_00035 0.00 0.00 0.00 0 70496 6 0 4 2 118
ASE_00040 0.02 0.01 0.07 1 78989 13 0 13 0 132
ASE_00064 0.00 0.00 0.00 0 45448 3 0 3 0 89
ASE_00068 0.05 0.01 0.25 1 37671 3 0 3 0 84
ASE_00075 0.00 0.00 0.00 0 108804 8 0 7 1 162
ASE_00077 0.09 0.02 0.33 2 45144 4 1 3 0 84
ASE_00078 0.00 0.00 0.00 0 43071 0 0 0 0 83
ASE_00080 0.00 0.00 0.00 0 71623 9 2 6 1 123
ASE_00081 0.00 0.00 0.00 0 49768 2 0 2 0 97
ASE_00082 0.00 0.00 0.00 0 70494 6 0 6 0 116
ASE_00083 0.00 0.00 0.00 0 62477 5 0 4 1 110
ASE_00084 0.00 0.00 0.00 0 53625 4 0 3 1 99
ASE_00087 0.00 0.00 0.00 0 88406 4 0 4 0 144
ASE_00092 0.04 0.01 0.20 1 63541 4 0 4 0 112
ASE_00104 0.10 0.03 0.31 4 64248 9 0 9 0 115
ASE_00107 0.13 0.03 0.50 4 73145 4 0 4 0 123
ASE_00115 0.00 0.00 0.00 0 54615 0 0 0 0 101
ASE_00119 0.00 0.00 0.00 0 62834 3 0 1 2 108
ASE_00123 0.00 0.00 0.00 0 38499 4 0 4 0 85
ASE_00135 0.00 0.00 0.00 0 63187 3 0 3 0 109
ASE_00138 0.00 0.00 0.00 0 40467 3 0 3 0 81
ASE_00142 0.06 0.02 0.25 2 67153 6 0 6 0 120
ASE_00146 0.09 0.02 0.38 3 70868 5 0 5 0 121
ASE_00153 0.00 0.00 0.00 0 57629 1 1 0 0 73
ASE_00163 0.00 0.00 0.00 0 53297 4 1 3 0 93
ASE_00170 0.04 0.01 0.17 1 48822 5 0 5 0 92
ASE_00174 0.00 0.00 0.00 0 61075 0 0 0 0 109
ASE_00179 0.09 0.04 0.23 3 44240 12 1 9 2 81
ASE_00180 0.00 0.00 0.00 0 51355 5 3 2 0 100
ASE_00182 0.00 0.00 0.00 0 84254 1 0 1 0 136
ASE_00184 0.09 0.03 0.30 3 54605 7 0 7 0 99
ASE_00185 0.00 0.00 0.00 0 73531 5 0 5 0 128
ASE_00186 0.00 0.00 0.00 0 78994 9 1 8 0 132
ASE_00190 0.00 0.00 0.00 0 45437 15 3 11 1 90
ASE_00212 0.00 0.00 0.00 0 93956 5 0 5 0 148
ASE_00214 0.00 0.00 0.00 0 56271 9 0 9 0 103
ASE_00215 0.00 0.00 0.00 0 48513 3 0 3 0 99
ASE_00217 0.16 0.04 0.57 4 40463 3 0 3 0 86
ASE_00221 0.00 0.00 0.00 0 64617 3 0 3 0 117
ASE_00228 0.00 0.00 0.00 0 46967 4 0 4 0 86
ASE_00229 0.00 0.00 0.00 0 42482 4 1 3 0 87
ASE_00238 0.07 0.01 0.50 1 64259 1 0 1 0 113
ASE_00241 0.00 0.00 0.00 0 43954 2 0 2 0 87
ASE_00248 0.11 0.03 0.43 3 62474 4 0 4 0 111
ASE_00255 0.12 0.03 0.50 4 74683 4 0 4 0 126
ASE_00257 0.00 0.00 0.00 0 51035 5 0 5 0 97
ASE_00267 0.00 0.00 0.00 0 45145 6 0 5 1 88
ASE_00270 0.00 0.00 0.00 0 72388 3 0 2 1 128
ASE_00279 0.00 0.00 0.00 0 53299 2 0 2 0 101
ASE_00280 0.00 0.00 0.00 0 52001 2 0 2 0 98
ASE_00281 0.00 0.00 0.00 0 44548 3 0 3 0 88
ASE_00283 0.00 0.00 0.00 0 61769 7 0 7 0 107
ASE_00285 0.00 0.00 0.00 0 69000 6 0 6 0 122
ASE_00292 0.15 0.04 0.50 6 81798 6 0 6 0 132
ASE_00294 0.08 0.02 0.31 4 114468 9 0 9 0 167
ASE_00297 0.00 0.00 0.00 0 52972 3 0 3 0 98
ASE_00298 0.00 0.00 0.00 0 67525 3 1 2 0 113
ASE_00318 0.00 0.00 0.00 0 80184 21 0 16 5 118
ASE_00328 0.00 0.00 0.00 0 72760 15 0 11 4 112
ASE_00332 0.15 0.04 0.50 6 81798 6 0 6 0 132
ASE_00335 0.00 0.00 0.00 0 75451 19 1 14 4 116
ASE_00340 0.04 0.01 0.14 1 46049 6 0 6 0 84
ASE_00353 0.00 0.00 0.00 0 57968 2 0 2 0 107
ASE_00361 0.00 0.00 0.00 0 75463 3 0 3 0 127
ASE_00362 0.00 0.00 0.00 0 48200 5 0 5 0 91
ASE_00363 0.00 0.00 0.00 0 51354 6 0 6 0 94
ASE_00364 0.11 0.02 0.67 2 54282 1 0 1 0 103
ASE_00366 0.00 0.00 0.00 0 58652 1 0 1 0 98
ASE_00367 0.00 0.00 0.00 0 43067 5 0 4 1 86
ASE_00372 0.00 0.00 0.00 0 51997 6 0 6 0 100
ASE_00376 0.04 0.01 0.17 1 56947 5 0 5 0 104
ASE_00382 0.06 0.01 0.33 1 41902 3 0 2 1 83
ASE_00384 0.05 0.01 0.20 1 48511 4 0 4 0 91
ASE_00386 0.10 0.03 0.33 3 50394 7 0 6 1 93
ASE_00387 0.00 0.00 0.00 0 55940 5 0 5 0 104
ASE_00388 0.00 0.00 0.00 0 45749 5 0 4 1 89
ASE_00390 0.00 0.00 0.00 0 42192 4 0 3 1 85
ASE_00393 0.00 0.00 0.00 0 47891 4 0 4 0 93
ASE_00394 0.03 0.01 0.07 1 46956 15 0 14 1 92
ASE_00395 0.00 0.00 0.00 0 41612 6 0 4 2 84
ASE_00396 0.15 0.04 0.60 3 41611 2 0 2 0 80
ASE_00397 0.04 0.01 0.17 1 54609 5 1 4 0 104
ASE_00398 0.00 0.00 0.00 0 55934 11 0 11 0 104
ASE_00400 0.08 0.02 0.33 2 57964 4 3 1 0 104
ASE_00402 0.05 0.01 0.25 1 42482 3 0 3 0 84
ASE_00404 0.00 0.00 0.00 0 43065 9 0 6 3 85
ASE_00406 0.00 0.00 0.00 0 48823 6 0 5 1 94
ASE_00411 0.11 0.02 0.50 2 49451 2 0 2 0 87
ASE_00412 0.04 0.01 0.17 1 58305 5 1 4 0 104
ASE_00416 0.00 0.00 0.00 0 77412 9 0 9 0 127
ASE_00419 0.10 0.03 0.33 3 54937 6 0 6 0 100
ASE_00422 0.05 0.02 0.12 2 46954 19 1 14 4 92
ASE_00423 0.14 0.04 0.50 4 56945 4 0 4 0 105
ASE_00428 0.00 0.00 0.00 0 76629 8 0 7 1 125
ASE_00430 0.07 0.02 0.25 2 46963 6 0 6 0 95
ASE_00437 0.00 0.00 0.00 0 79395 7 0 6 1 135
ASE_00448 0.04 0.01 0.14 1 64254 6 1 5 0 111
ASE_00451 0.11 0.03 0.36 4 70865 7 0 7 0 121
RFA_00599 0.43 0.25 0.74 28 101437 25 0 10 15 83
RFA_00601 0.57 0.38 0.86 43 99185 16 1 6 9 71
RFA_00602 0.09 0.02 0.50 2 101471 3 1 1 1 114

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.