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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of Cylofold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & Cylofold [.zip] - may take several seconds...


Overview

Metric RNASLOpt Cylofold
MCC 0.382 > 0.271
Average MCC ± 95% Confidence Intervals 0.386 ± 2.005 > 0.275 ± 1.303
Sensitivity 0.358 > 0.241
Positive Predictive Value 0.412 > 0.308
Total TP 49 > 33
Total TN 60469 < 60481
Total FP 73 < 78
Total FP CONTRA 5 > 3
Total FP INCONS 65 < 71
Total FP COMP 3 < 4
Total FN 88 < 104
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASLOpt and Cylofold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and Cylofold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and Cylofold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and Cylofold).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 49
Total TN 60469
Total FP 73
Total FP CONTRA 5
Total FP INCONS 65
Total FP COMP 3
Total FN 88
Total Scores
MCC 0.382
Average MCC ± 95% Confidence Intervals 0.386 ± 2.005
Sensitivity 0.358
Positive Predictive Value 0.412
Nr of predictions 2

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00408 - 0.23 0.21 0.25 15 32325 47 2 43 2 56
ASE_00429 - 0.54 0.52 0.58 34 28144 26 3 22 1 32

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Performance of Cylofold - scored lower in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 33
Total TN 60481
Total FP 78
Total FP CONTRA 3
Total FP INCONS 71
Total FP COMP 4
Total FN 104
Total Scores
MCC 0.271
Average MCC ± 95% Confidence Intervals 0.275 ± 1.303
Sensitivity 0.241
Positive Predictive Value 0.308
Nr of predictions 2

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00408 - 0.17 0.15 0.20 11 32329 45 3 42 0 60
ASE_00429 - 0.38 0.33 0.43 22 28152 33 0 29 4 44

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.

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