CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RSpredict(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RSpredict(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric RSpredict(20) Carnac(seed)
MCC 0.469 > 0.000
Average MCC ± 95% Confidence Intervals 0.470 ± 0.127 > 0.000 ± 0.000
Sensitivity 0.323 > 0.000
Positive Predictive Value 0.683 > 0.000
Total TP 110 > 0
Total TN 302024 < 302185
Total FP 82 > 0
Total FP CONTRA 3 > 0
Total FP INCONS 48 > 0
Total FP COMP 31 > 0
Total FN 231 < 341
P-value 0.0

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Performance plots


  1. Comparison of performance of RSpredict(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RSpredict(20) and Carnac(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for RSpredict(20) and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RSpredict(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RSpredict(20) and Carnac(seed)).

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Performance of RSpredict(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RSpredict(20)

Total Base Pair Counts
Total TP 110
Total TN 302024
Total FP 82
Total FP CONTRA 3
Total FP INCONS 48
Total FP COMP 31
Total FN 231
Total Scores
MCC 0.469
Average MCC ± 95% Confidence Intervals 0.470 ± 0.127
Sensitivity 0.323
Positive Predictive Value 0.683
Nr of predictions 3

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2. Individual counts for RSpredict(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00599 0.44 0.32 0.61 36 101416 35 2 21 12 75
RFA_00601 0.53 0.35 0.80 40 99185 20 0 10 10 74
RFA_00602 0.44 0.29 0.65 34 101423 27 1 17 9 82

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 0
Total TN 302185
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 341
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 3

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00599 0.00 0.00 0.00 0 101475 0 0 0 0 111
RFA_00601 0.00 0.00 0.00 0 99235 0 0 0 0 114
RFA_00602 0.00 0.00 0.00 0 101475 0 0 0 0 116

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.