CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric TurboFold(20) Carnac(seed)
MCC 0.781 > 0.000
Average MCC ± 95% Confidence Intervals 0.781 ± 0.147 > 0.000 ± 0.000
Sensitivity 0.777 > 0.000
Positive Predictive Value 0.786 > 0.000
Total TP 265 > 0
Total TN 301848 < 302185
Total FP 128 > 0
Total FP CONTRA 17 > 0
Total FP INCONS 55 > 0
Total FP COMP 56 > 0
Total FN 76 < 341
P-value 0.0

^top




Performance plots


  1. Comparison of performance of TurboFold(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Carnac(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for TurboFold(20) and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Carnac(seed)).

^top





Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 265
Total TN 301848
Total FP 128
Total FP CONTRA 17
Total FP INCONS 55
Total FP COMP 56
Total FN 76
Total Scores
MCC 0.781
Average MCC ± 95% Confidence Intervals 0.781 ± 0.147
Sensitivity 0.777
Positive Predictive Value 0.786
Nr of predictions 3

^top



2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00599 0.74 0.74 0.74 82 101364 50 9 20 21 29
RFA_00601 0.76 0.75 0.77 85 99124 46 3 23 20 29
RFA_00602 0.85 0.84 0.85 98 101360 32 5 12 15 18

^top



Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 0
Total TN 302185
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 341
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 3

^top



2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
RFA_00599 0.00 0.00 0.00 0 101475 0 0 0 0 111
RFA_00601 0.00 0.00 0.00 0 99235 0 0 0 0 114
RFA_00602 0.00 0.00 0.00 0 101475 0 0 0 0 116

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.