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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of Contrafold - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & Contrafold [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) Contrafold
MCC 0.710 > 0.581
Average MCC ± 95% Confidence Intervals 0.710 ± > 0.581 ±
Sensitivity 0.677 > 0.600
Positive Predictive Value 0.746 > 0.565
Total TP 44 > 39
Total TN 27202 > 27192
Total FP 16 < 31
Total FP CONTRA 4 < 7
Total FP INCONS 11 < 23
Total FP COMP 1 = 1
Total FN 21 < 26
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(seed) and Contrafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and Contrafold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and Contrafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and Contrafold).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 44
Total TN 27202
Total FP 16
Total FP CONTRA 4
Total FP INCONS 11
Total FP COMP 1
Total FN 21
Total Scores
MCC 0.710
Average MCC ± 95% Confidence Intervals 0.710 ±
Sensitivity 0.677
Positive Predictive Value 0.746
Nr of predictions 1

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00210 0.71 0.68 0.75 44 27202 16 4 11 1 21

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Performance of Contrafold - scored lower in this pairwise comparison

1. Total counts & total scores for Contrafold

Total Base Pair Counts
Total TP 39
Total TN 27192
Total FP 31
Total FP CONTRA 7
Total FP INCONS 23
Total FP COMP 1
Total FN 26
Total Scores
MCC 0.581
Average MCC ± 95% Confidence Intervals 0.581 ±
Sensitivity 0.600
Positive Predictive Value 0.565
Nr of predictions 1

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2. Individual counts for Contrafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00210 0.58 0.60 0.57 39 27192 31 7 23 1 26

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.