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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of McQFold - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & McQFold [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) McQFold
MCC 0.710 > 0.566
Average MCC ± 95% Confidence Intervals 0.710 ± > 0.566 ±
Sensitivity 0.677 > 0.554
Positive Predictive Value 0.746 > 0.581
Total TP 44 > 36
Total TN 27202 > 27199
Total FP 16 < 28
Total FP CONTRA 4 < 6
Total FP INCONS 11 < 20
Total FP COMP 1 < 2
Total FN 21 < 29
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(seed) and McQFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and McQFold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and McQFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and McQFold).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 44
Total TN 27202
Total FP 16
Total FP CONTRA 4
Total FP INCONS 11
Total FP COMP 1
Total FN 21
Total Scores
MCC 0.710
Average MCC ± 95% Confidence Intervals 0.710 ±
Sensitivity 0.677
Positive Predictive Value 0.746
Nr of predictions 1

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00210 0.71 0.68 0.75 44 27202 16 4 11 1 21

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Performance of McQFold - scored lower in this pairwise comparison

1. Total counts & total scores for McQFold

Total Base Pair Counts
Total TP 36
Total TN 27199
Total FP 28
Total FP CONTRA 6
Total FP INCONS 20
Total FP COMP 2
Total FN 29
Total Scores
MCC 0.566
Average MCC ± 95% Confidence Intervals 0.566 ±
Sensitivity 0.554
Positive Predictive Value 0.581
Nr of predictions 1

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2. Individual counts for McQFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
ASE_00210 0.57 0.55 0.58 36 27199 28 6 20 2 29

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.