CompaRNA - on-line benchmarks of RNA structure prediction methods

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Metric	Vsfold5		CMfinder(seed)
MCC	0.346	>	0.343
Average MCC ± 95% Confidence Intervals	0.336 ± 0.076	<	0.348 ± 0.069
Sensitivity	0.322	>	0.157
Positive Predictive Value	0.374	<	0.750
Total TP	418	>	204
Total TN	810021	<	810867
Total FP	762	>	68
Total FP CONTRA	95	>	3
Total FP INCONS	605	>	65
Total FP COMP	62	>	0
Total FN	880	<	1094
P-value	0.0869137492703

Comparison of performance of Vsfold5 and CMfinder(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Vsfold5 and CMfinder(seed)).
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Vsfold5 and CMfinder(seed)).
Comparison of average Matthews Correlation Coefficients (MCCs) for Vsfold5 and CMfinder(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Vsfold5 and CMfinder(seed)).

Total Scores
MCC	0.346
Average MCC ± 95% Confidence Intervals	0.336 ± 0.076
Sensitivity	0.322
Positive Predictive Value	0.374
Nr of predictions	13

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
CRW_00016	Intron_gpI links to Rfam database...	0.40	0.38	0.42	45	77315	67	4	57	6	75
CRW_00610	Intron_gpI links to Rfam database...	0.29	0.28	0.30	23	36238	57	6	48	3	58
CRW_00613	Intron_gpI links to Rfam database...	0.48	0.46	0.51	36	34909	41	2	33	6	42
CRW_00618	Intron_gpI links to Rfam database...	0.24	0.26	0.23	16	56210	76	9	45	22	45
CRW_00633	Intron_gpI links to Rfam database...	0.00	0.00	0.00	0	63546	0	0	0	0	106
CRW_00634	Intron_gpI links to Rfam database...	0.32	0.33	0.32	31	64523	75	10	56	9	63
CRW_00670	Intron_gpI links to Rfam database...	0.40	0.38	0.43	45	70020	61	3	57	1	75
CRW_00671	Intron_gpI links to Rfam database...	0.29	0.26	0.33	31	62740	64	2	62	0	86
CRW_00672	Intron_gpI links to Rfam database...	0.39	0.40	0.39	44	72278	70	14	54	2	67
CRW_00674	Intron_gpI links to Rfam database...	0.33	0.31	0.36	38	83330	74	5	63	6	86
CRW_00676	Intron_gpI links to Rfam database...	0.34	0.36	0.33	41	93405	88	19	63	6	74
CRW_00692	Intron_gpI links to Rfam database...	0.36	0.38	0.34	34	68534	67	21	46	0	56
PDB_00827	Intron_gpI links to Rfam database...	0.51	0.42	0.62	34	26973	22	0	21	1	47

Total Scores
MCC	0.343
Average MCC ± 95% Confidence Intervals	0.348 ± 0.069
Sensitivity	0.157
Positive Predictive Value	0.750
Nr of predictions	13

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
CRW_00016	Intron_gpI links to Rfam database...	0.36	0.14	0.89	17	77402	2	0	2	0	103
CRW_00610	Intron_gpI links to Rfam database...	0.49	0.31	0.78	25	36283	7	1	6	0	56
CRW_00613	Intron_gpI links to Rfam database...	0.54	0.33	0.87	26	34950	4	0	4	0	52
CRW_00618	Intron_gpI links to Rfam database...	0.36	0.13	1.00	8	56272	0	0	0	0	53
CRW_00633	Intron_gpI links to Rfam database...	0.32	0.12	0.81	13	63530	3	1	2	0	93
CRW_00634	Intron_gpI links to Rfam database...	0.40	0.17	0.94	16	64603	1	0	1	0	78
CRW_00670	Intron_gpI links to Rfam database...	0.32	0.18	0.55	22	70085	18	0	18	0	98
CRW_00671	Intron_gpI links to Rfam database...	0.20	0.09	0.41	11	62808	16	0	16	0	106
CRW_00672	Intron_gpI links to Rfam database...	0.38	0.15	0.94	17	72372	1	0	1	0	94
CRW_00674	Intron_gpI links to Rfam database...	0.40	0.17	0.95	21	83414	1	0	1	0	103
CRW_00676	Intron_gpI links to Rfam database...	0.12	0.04	0.33	5	93513	10	1	9	0	110
CRW_00692	Intron_gpI links to Rfam database...	0.41	0.17	1.00	15	68620	0	0	0	0	75
PDB_00827	Intron_gpI links to Rfam database...	0.25	0.10	0.62	8	27015	5	0	5	0	73

Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.