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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidAlifold(seed) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric CentroidAlifold(seed) Carnac(seed)
MCC 0.902 > 0.729
Average MCC ± 95% Confidence Intervals 0.902 ± > 0.729 ±
Sensitivity 0.858 > 0.570
Positive Predictive Value 0.949 > 0.932
Total TP 393 > 261
Total TN 1085187 < 1085321
Total FP 55 > 35
Total FP CONTRA 6 = 6
Total FP INCONS 15 > 13
Total FP COMP 34 > 16
Total FN 65 < 197
P-value 0.0

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Performance plots


  1. Comparison of performance of CentroidAlifold(seed) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidAlifold(seed) and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidAlifold(seed) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidAlifold(seed) and Carnac(seed)).

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Performance of CentroidAlifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(seed)

Total Base Pair Counts
Total TP 393
Total TN 1085187
Total FP 55
Total FP CONTRA 6
Total FP INCONS 15
Total FP COMP 34
Total FN 65
Total Scores
MCC 0.902
Average MCC ± 95% Confidence Intervals 0.902 ±
Sensitivity 0.858
Positive Predictive Value 0.949
Nr of predictions 1

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2. Individual counts for CentroidAlifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.90 0.86 0.95 393 1085187 55 6 15 34 65

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 261
Total TN 1085321
Total FP 35
Total FP CONTRA 6
Total FP INCONS 13
Total FP COMP 16
Total FN 197
Total Scores
MCC 0.729
Average MCC ± 95% Confidence Intervals 0.729 ±
Sensitivity 0.570
Positive Predictive Value 0.932
Nr of predictions 1

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.73 0.57 0.93 261 1085321 35 6 13 16 197

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.