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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidFold - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidFold & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric CentroidFold Mastr(seed)
MCC 0.432 > 0.000
Average MCC ± 95% Confidence Intervals 0.435 ± 1.845 > 0.000 ± 0.000
Sensitivity 0.376 > 0.000
Positive Predictive Value 0.497 > 0.000
Total TP 350 > 0
Total TN 2847121 < 2847825
Total FP 458 > 0
Total FP CONTRA 60 > 0
Total FP INCONS 294 > 0
Total FP COMP 104 > 0
Total FN 582 < 932
P-value 0.0

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Performance plots


  1. Comparison of performance of CentroidFold and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidFold and Mastr(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidFold and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidFold and Mastr(seed)).

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Performance of CentroidFold - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidFold

Total Base Pair Counts
Total TP 350
Total TN 2847121
Total FP 458
Total FP CONTRA 60
Total FP INCONS 294
Total FP COMP 104
Total FN 582
Total Scores
MCC 0.432
Average MCC ± 95% Confidence Intervals 0.435 ± 1.845
Sensitivity 0.376
Positive Predictive Value 0.497
Nr of predictions 2

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2. Individual counts for CentroidFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00306 0.29 0.26 0.32 120 1445480 309 50 200 59 342
CRW_00800 0.58 0.49 0.69 230 1401641 149 10 94 45 240

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 2847825
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 932
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 2

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00306 0.00 0.00 0.00 0 1445850 0 0 0 0 462
CRW_00800 0.00 0.00 0.00 0 1401975 0 0 0 0 470

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.