CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CentroidFold - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for CentroidFold & RNASLOpt [.zip] - may take several seconds...


Overview

Metric CentroidFold RNASLOpt
MCC 0.307 > 0.000
Average MCC ± 95% Confidence Intervals 0.307 ± > 0.000 ±
Sensitivity 0.212 > 0.000
Positive Predictive Value 0.447 > 0.000
Total TP 55 > 0
Total TN 456367 < 456490
Total FP 78 > 0
Total FP CONTRA 4 > 0
Total FP INCONS 64 > 0
Total FP COMP 10 > 0
Total FN 205 < 260
P-value 0.0

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Performance plots


  1. Comparison of performance of CentroidFold and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CentroidFold and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CentroidFold and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CentroidFold and RNASLOpt).

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Performance of CentroidFold - scored higher in this pairwise comparison

1. Total counts & total scores for CentroidFold

Total Base Pair Counts
Total TP 55
Total TN 456367
Total FP 78
Total FP CONTRA 4
Total FP INCONS 64
Total FP COMP 10
Total FN 205
Total Scores
MCC 0.307
Average MCC ± 95% Confidence Intervals 0.307 ±
Sensitivity 0.212
Positive Predictive Value 0.447
Nr of predictions 1

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2. Individual counts for CentroidFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00443 - 0.31 0.21 0.45 55 456367 78 4 64 10 205

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 0
Total TN 456490
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 260
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ±
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 1

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00443 - 0.00 0.00 0.00 0 456490 0 0 0 0 260

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.