CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Contrafold - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Contrafold & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric Contrafold Carnac(seed)
MCC 0.775 > 0.729
Average MCC ± 95% Confidence Intervals 0.775 ± > 0.729 ±
Sensitivity 0.766 > 0.570
Positive Predictive Value 0.783 < 0.932
Total TP 351 > 261
Total TN 1085153 < 1085321
Total FP 140 > 35
Total FP CONTRA 12 > 6
Total FP INCONS 85 > 13
Total FP COMP 43 > 16
Total FN 107 < 197
P-value 0.0

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Performance plots


  1. Comparison of performance of Contrafold and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Contrafold and Carnac(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Contrafold and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Contrafold and Carnac(seed)).

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Performance of Contrafold - scored higher in this pairwise comparison

1. Total counts & total scores for Contrafold

Total Base Pair Counts
Total TP 351
Total TN 1085153
Total FP 140
Total FP CONTRA 12
Total FP INCONS 85
Total FP COMP 43
Total FN 107
Total Scores
MCC 0.775
Average MCC ± 95% Confidence Intervals 0.775 ±
Sensitivity 0.766
Positive Predictive Value 0.783
Nr of predictions 1

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2. Individual counts for Contrafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.77 0.77 0.78 351 1085153 140 12 85 43 107

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 261
Total TN 1085321
Total FP 35
Total FP CONTRA 6
Total FP INCONS 13
Total FP COMP 16
Total FN 197
Total Scores
MCC 0.729
Average MCC ± 95% Confidence Intervals 0.729 ±
Sensitivity 0.570
Positive Predictive Value 0.932
Nr of predictions 1

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00024 0.73 0.57 0.93 261 1085321 35 6 13 16 197

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.