CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Contrafold - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for Contrafold & RNASLOpt [.zip] - may take several seconds...


Overview

Metric Contrafold RNASLOpt
MCC 0.336 > 0.000
Average MCC ± 95% Confidence Intervals 0.336 ± > 0.000 ±
Sensitivity 0.262 > 0.000
Positive Predictive Value 0.433 > 0.000
Total TP 68 > 0
Total TN 456333 < 456490
Total FP 107 > 0
Total FP CONTRA 8 > 0
Total FP INCONS 81 > 0
Total FP COMP 18 > 0
Total FN 192 < 260
P-value 0.0

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Performance plots


  1. Comparison of performance of Contrafold and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Contrafold and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Contrafold and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Contrafold and RNASLOpt).

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Performance of Contrafold - scored higher in this pairwise comparison

1. Total counts & total scores for Contrafold

Total Base Pair Counts
Total TP 68
Total TN 456333
Total FP 107
Total FP CONTRA 8
Total FP INCONS 81
Total FP COMP 18
Total FN 192
Total Scores
MCC 0.336
Average MCC ± 95% Confidence Intervals 0.336 ±
Sensitivity 0.262
Positive Predictive Value 0.433
Nr of predictions 1

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2. Individual counts for Contrafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00443 - 0.34 0.26 0.43 68 456333 107 8 81 18 192

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 0
Total TN 456490
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 260
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ±
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 1

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00443 - 0.00 0.00 0.00 0 456490 0 0 0 0 260

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.