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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MaxExpect - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for MaxExpect & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric MaxExpect Mastr(seed)
MCC 0.387 > 0.000
Average MCC ± 95% Confidence Intervals 0.389 ± 0.465 > 0.000 ± 0.000
Sensitivity 0.381 > 0.000
Positive Predictive Value 0.393 > 0.000
Total TP 559 > 0
Total TN 4973354 < 4974778
Total FP 1078 > 0
Total FP CONTRA 139 > 0
Total FP INCONS 726 > 0
Total FP COMP 213 > 0
Total FN 907 < 1466
P-value 0.0

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Performance plots


  1. Comparison of performance of MaxExpect and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MaxExpect and Mastr(seed)).

  2. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for MaxExpect and Mastr(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for MaxExpect and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MaxExpect and Mastr(seed)).

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Performance of MaxExpect - scored higher in this pairwise comparison

1. Total counts & total scores for MaxExpect

Total Base Pair Counts
Total TP 559
Total TN 4973354
Total FP 1078
Total FP CONTRA 139
Total FP INCONS 726
Total FP COMP 213
Total FN 907
Total Scores
MCC 0.387
Average MCC ± 95% Confidence Intervals 0.389 ± 0.465
Sensitivity 0.381
Positive Predictive Value 0.393
Nr of predictions 3

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2. Individual counts for MaxExpect [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00306 0.18 0.19 0.18 86 1445370 462 62 332 68 376
CRW_00379 0.44 0.44 0.43 234 2126414 384 57 248 79 300
CRW_00800 0.55 0.51 0.59 239 1401570 232 20 146 66 231

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 4974778
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 1466
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 3

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00306 0.00 0.00 0.00 0 1445850 0 0 0 0 462
CRW_00379 0.00 0.00 0.00 0 2126953 0 0 0 0 534
CRW_00800 0.00 0.00 0.00 0 1401975 0 0 0 0 470

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.