CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of McQFold - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for McQFold & RNASLOpt [.zip] - may take several seconds...


Overview

Metric McQFold RNASLOpt
MCC 0.155 > 0.000
Average MCC ± 95% Confidence Intervals 0.155 ± > 0.000 ±
Sensitivity 0.131 > 0.000
Positive Predictive Value 0.184 > 0.000
Total TP 34 > 0
Total TN 456305 < 456490
Total FP 172 > 0
Total FP CONTRA 19 > 0
Total FP INCONS 132 > 0
Total FP COMP 21 > 0
Total FN 226 < 260
P-value 0.0

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Performance plots


  1. Comparison of performance of McQFold and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for McQFold and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for McQFold and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for McQFold and RNASLOpt).

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Performance of McQFold - scored higher in this pairwise comparison

1. Total counts & total scores for McQFold

Total Base Pair Counts
Total TP 34
Total TN 456305
Total FP 172
Total FP CONTRA 19
Total FP INCONS 132
Total FP COMP 21
Total FN 226
Total Scores
MCC 0.155
Average MCC ± 95% Confidence Intervals 0.155 ±
Sensitivity 0.131
Positive Predictive Value 0.184
Nr of predictions 1

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2. Individual counts for McQFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00443 - 0.15 0.13 0.18 34 456305 172 19 132 21 226

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 0
Total TN 456490
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 260
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ±
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 1

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00443 - 0.00 0.00 0.00 0 456490 0 0 0 0 260

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.