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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of Mastr(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & Mastr(20) [.zip] - may take several seconds...


Overview

Metric PPfold(20) Mastr(20)
MCC 0.598 > 0.000
Average MCC ± 95% Confidence Intervals 0.598 ± 0.525 > 0.000 ± 0.000
Sensitivity 0.521 > 0.000
Positive Predictive Value 0.686 > 0.000
Total TP 526 > 0
Total TN 3302708 < 3303475
Total FP 321 > 0
Total FP CONTRA 32 > 0
Total FP INCONS 209 > 0
Total FP COMP 80 > 0
Total FN 483 < 1009
P-value 0.0

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Performance plots


  1. Comparison of performance of PPfold(20) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and Mastr(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and Mastr(20)).

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Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 526
Total TN 3302708
Total FP 321
Total FP CONTRA 32
Total FP INCONS 209
Total FP COMP 80
Total FN 483
Total Scores
MCC 0.598
Average MCC ± 95% Confidence Intervals 0.598 ± 0.525
Sensitivity 0.521
Positive Predictive Value 0.686
Nr of predictions 2

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00326 0.64 0.56 0.73 280 1627728 143 17 85 41 222
CRW_00358 0.56 0.49 0.64 246 1674980 178 15 124 39 261

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Performance of Mastr(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 0
Total TN 3303475
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 1009
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 2

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00326 0.00 0.00 0.00 0 1628110 0 0 0 0 502
CRW_00358 0.00 0.00 0.00 0 1675365 0 0 0 0 507

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.