CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAfold - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAfold & RNASLOpt [.zip] - may take several seconds...


Overview

Metric RNAfold RNASLOpt
MCC 0.386 > 0.000
Average MCC ± 95% Confidence Intervals 0.386 ± > 0.000 ±
Sensitivity 0.358 > 0.000
Positive Predictive Value 0.417 > 0.000
Total TP 93 > 0
Total TN 456267 < 456490
Total FP 151 > 0
Total FP CONTRA 22 > 0
Total FP INCONS 108 > 0
Total FP COMP 21 > 0
Total FN 167 < 260
P-value 0.0

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Performance plots


  1. Comparison of performance of RNAfold and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAfold and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAfold and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAfold and RNASLOpt).

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Performance of RNAfold - scored higher in this pairwise comparison

1. Total counts & total scores for RNAfold

Total Base Pair Counts
Total TP 93
Total TN 456267
Total FP 151
Total FP CONTRA 22
Total FP INCONS 108
Total FP COMP 21
Total FN 167
Total Scores
MCC 0.386
Average MCC ± 95% Confidence Intervals 0.386 ±
Sensitivity 0.358
Positive Predictive Value 0.417
Nr of predictions 1

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2. Individual counts for RNAfold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00443 - 0.39 0.36 0.42 93 456267 151 22 108 21 167

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 0
Total TN 456490
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 260
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ±
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 1

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00443 - 0.00 0.00 0.00 0 456490 0 0 0 0 260

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.