CompaRNA - on-line benchmarks of RNA structure prediction methods

Laboratory of Structural Bioinformatics @ Adam Mickiewicz University in Poznan

Home

Methods

Datasets

Rankings

RNA 2D Atlas

Help

FAQ

Contact us

RSS feeds

Twitter

Overview

Metric	RSpredict(seed)		Fold
MCC	0.532	>	0.407
Average MCC ± 95% Confidence Intervals	0.529 ± 0.062	>	0.408 ± 0.027
Sensitivity	0.447	>	0.409
Positive Predictive Value	0.632	>	0.406
Total TP	12037	>	10997
Total TN	71042306	>	71034276
Total FP	8416	<	17687
Total FP CONTRA	1137	<	2253
Total FP INCONS	5864	<	13818
Total FP COMP	1415	<	1616
Total FN	14867	<	15907
P-value	3.56938820447e-08

^top

Performance plots

Comparison of performance of RSpredict(seed) and Fold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RSpredict(seed) and Fold).
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for RSpredict(seed) and Fold).
Comparison of average Matthews Correlation Coefficients (MCCs) for RSpredict(seed) and Fold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RSpredict(seed) and Fold).

^top

Performance of RSpredict(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RSpredict(seed)

Total Base Pair Counts
Total TP	12037
Total TN	71042306
Total FP	8416
Total FP CONTRA	1137
Total FP INCONS	5864
Total FP COMP	1415
Total FN	14867

Total Scores
MCC	0.532
Average MCC ± 95% Confidence Intervals	0.529 ± 0.062
Sensitivity	0.447
Positive Predictive Value	0.632
Nr of predictions	57

^top

2. Individual counts for RSpredict(seed) [ download as .csv ]

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
CRW_00024	SSU_rRNA_archaea links to Rfam database...	0.78	0.76	0.80	346	1085169	116	15	71	30	112
CRW_00048	SSU_rRNA_bacteria links to Rfam database...	0.65	0.57	0.74	268	1170853	120	15	79	26	202
CRW_00054	SSU_rRNA_bacteria links to Rfam database...	0.66	0.59	0.75	269	1107457	114	15	75	24	187
CRW_00059	SSU_rRNA_bacteria links to Rfam database...	0.63	0.54	0.73	257	1172394	120	18	77	25	216
CRW_00061	SSU_rRNA_bacteria links to Rfam database...	0.62	0.54	0.72	258	1181594	124	19	82	23	218
CRW_00068	SSU_rRNA_bacteria links to Rfam database...	0.65	0.57	0.75	261	1108955	113	16	73	24	196
CRW_00096	SSU_rRNA_bacteria links to Rfam database...	0.66	0.57	0.75	267	1178524	119	14	75	30	198
CRW_00140	SSU_rRNA_bacteria links to Rfam database...	0.67	0.59	0.76	273	1135921	112	13	71	28	190
CRW_00141	SSU_rRNA_bacteria links to Rfam database...	0.63	0.55	0.72	260	1201662	126	16	87	23	216
CRW_00150	SSU_rRNA_bacteria links to Rfam database...	0.66	0.58	0.74	270	1152558	117	19	74	24	196
CRW_00152	SSU_rRNA_bacteria links to Rfam database...	0.63	0.54	0.74	252	1180075	110	15	74	21	219
CRW_00166	SSU_rRNA_bacteria links to Rfam database...	0.64	0.55	0.74	258	1190849	118	11	78	29	210
CRW_00173	SSU_rRNA_bacteria links to Rfam database...	0.62	0.55	0.71	243	1082316	119	17	80	22	202
CRW_00177	SSU_rRNA_bacteria links to Rfam database...	0.67	0.58	0.77	274	1178524	103	15	67	21	199
CRW_00196	SSU_rRNA_bacteria links to Rfam database...	0.63	0.54	0.73	257	1207883	117	16	79	22	218
CRW_00230	SSU_rRNA_bacteria links to Rfam database...	0.62	0.54	0.71	257	1198565	127	16	88	23	221
CRW_00245	SSU_rRNA_bacteria links to Rfam database...	0.63	0.55	0.72	248	1105984	121	17	79	25	205
CRW_00248	SSU_rRNA_bacteria links to Rfam database...	0.65	0.57	0.75	278	1218768	123	17	78	28	206
CRW_00250	SSU_rRNA_bacteria links to Rfam database...	0.67	0.60	0.74	285	1198543	124	18	80	26	193
CRW_00256	SSU_rRNA_bacteria links to Rfam database...	0.62	0.54	0.72	251	1192392	119	17	80	22	217
CRW_00270	SSU_rRNA_bacteria links to Rfam database...	0.64	0.56	0.74	255	1111941	113	15	75	23	200
CRW_00271	SSU_rRNA_bacteria links to Rfam database...	0.62	0.53	0.73	243	1122417	115	15	76	24	219
CRW_00273	SSU_rRNA_bacteria links to Rfam database...	0.64	0.56	0.73	250	1085260	113	15	76	22	196
CRW_00275	SSU_rRNA_bacteria links to Rfam database...	0.63	0.54	0.72	249	1114926	120	15	81	24	208
CRW_00277	SSU_rRNA_bacteria links to Rfam database...	0.61	0.52	0.72	235	1110468	113	17	75	21	218
CRW_00280	SSU_rRNA_bacteria links to Rfam database...	0.61	0.53	0.70	240	1117918	122	15	87	20	213
CRW_00281	SSU_rRNA_bacteria links to Rfam database...	0.65	0.56	0.74	260	1144991	117	12	78	27	204
CRW_00283	SSU_rRNA_bacteria links to Rfam database...	0.53	0.42	0.68	180	1015761	96	14	70	12	252
CRW_00289	SSU_rRNA_bacteria links to Rfam database...	0.60	0.50	0.70	240	1189312	122	16	85	21	236
CRW_00292	SSU_rRNA_bacteria links to Rfam database...	0.55	0.43	0.72	196	1123976	99	12	66	21	265
CRW_00306	SSU_rRNA_eukarya links to Rfam database...	0.00	0.00	0.00	0	1445558	306	53	239	14	462
CRW_00366	SSU_rRNA_eukarya links to Rfam database...	0.00	0.00	0.00	0	1579464	301	50	239	12	482
CRW_00371	SSU_rRNA_eukarya links to Rfam database...	0.00	0.00	0.00	0	1611598	319	50	262	7	496
CRW_00379	SSU_rRNA_eukarya links to Rfam database...	0.00	0.00	0.00	0	2126581	414	77	295	42	534
CRW_00411	SSU_rRNA_eukarya links to Rfam database...	0.00	0.00	0.00	0	1615206	309	45	252	12	496
CRW_00414	SSU_rRNA_eukarya links to Rfam database...	0.00	0.00	0.00	0	1665933	312	53	239	20	495
CRW_00466	SSU_rRNA_bacteria links to Rfam database...	0.64	0.55	0.74	252	1116423	114	13	77	24	206
CRW_00589	SSU_rRNA_bacteria links to Rfam database...	0.63	0.53	0.74	236	1094141	110	9	74	27	209
CRW_00590	SSU_rRNA_bacteria links to Rfam database...	0.64	0.54	0.76	245	1119432	103	8	71	24	207
CRW_00591	SSU_rRNA_bacteria links to Rfam database...	0.66	0.58	0.76	258	1098562	118	11	72	35	188
CRW_00759	SSU_rRNA_eukarya links to Rfam database...	0.00	0.00	0.00	1	1636859	310	50	235	25	480
CRW_00763	SSU_rRNA_bacteria links to Rfam database...	0.62	0.49	0.79	217	1215744	86	5	54	27	229
CRW_00778	SSU_rRNA_bacteria links to Rfam database...	0.59	0.48	0.73	185	1201773	99	7	60	32	199
CRW_00789	SSU_rRNA_bacteria links to Rfam database...	0.64	0.56	0.74	249	1137451	114	13	73	28	198
CRW_00795	SSU_rRNA_bacteria links to Rfam database...	0.58	0.47	0.72	184	1152666	117	7	64	46	210
CRW_00849	SSU_rRNA_bacteria links to Rfam database...	0.60	0.49	0.73	232	1117943	100	11	74	15	238
CRW_00997	SSU_rRNA_bacteria links to Rfam database...	0.63	0.55	0.72	256	1135921	123	14	87	22	208
CRW_01153	SSU_rRNA_eukarya links to Rfam database...	0.00	0.00	0.00	0	1606225	319	65	238	16	503
CRW_01171	SSU_rRNA_eukarya links to Rfam database...	0.00	0.00	0.00	0	1593701	318	50	254	14	506
CRW_01343	SSU_rRNA_archaea links to Rfam database...	0.52	0.41	0.68	177	977639	95	12	73	10	257
PDB_00703	SSU_rRNA_bacteria links to Rfam database...	0.63	0.53	0.76	261	1073500	115	11	73	31	234
PDB_00854	SSU_rRNA_bacteria links to Rfam database...	0.60	0.48	0.76	259	1500435	126	9	75	42	276
PDB_01088	SSU_rRNA_bacteria links to Rfam database...	0.60	0.47	0.76	259	1471129	122	8	74	40	288
PDB_01103	SSU_rRNA_bacteria links to Rfam database...	0.60	0.47	0.76	266	1606178	119	12	72	35	296
PDB_01105	SSU_rRNA_bacteria links to Rfam database...	0.61	0.50	0.76	268	1433617	119	7	79	33	272
PDB_01120	SSU_rRNA_bacteria links to Rfam database...	0.64	0.53	0.78	280	1204768	120	9	71	40	247
PDB_01273	SSU_rRNA_bacteria links to Rfam database...	0.65	0.55	0.76	272	1117903	116	13	72	31	219

^top

Performance of Fold - scored lower in this pairwise comparison

1. Total counts & total scores for Fold

Total Base Pair Counts
Total TP	10997
Total TN	71034276
Total FP	17687
Total FP CONTRA	2253
Total FP INCONS	13818
Total FP COMP	1616
Total FN	15907

Total Scores
MCC	0.407
Average MCC ± 95% Confidence Intervals	0.408 ± 0.027
Sensitivity	0.409
Positive Predictive Value	0.406
Nr of predictions	57

^top

2. Individual counts for Fold [ download as .csv ]

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
CRW_00024	SSU_rRNA_archaea links to Rfam database...	0.56	0.57	0.56	259	1085140	238	22	180	36	199
CRW_00048	SSU_rRNA_bacteria links to Rfam database...	0.51	0.51	0.52	239	1170753	241	24	199	18	231
CRW_00054	SSU_rRNA_bacteria links to Rfam database...	0.40	0.41	0.40	185	1107355	286	30	246	10	271
CRW_00059	SSU_rRNA_bacteria links to Rfam database...	0.44	0.44	0.44	207	1172278	279	31	230	18	266
CRW_00061	SSU_rRNA_bacteria links to Rfam database...	0.54	0.54	0.54	259	1181475	236	33	186	17	217
CRW_00068	SSU_rRNA_bacteria links to Rfam database...	0.43	0.43	0.43	198	1108845	279	32	230	17	259
CRW_00096	SSU_rRNA_bacteria links to Rfam database...	0.42	0.43	0.42	200	1178403	299	28	249	22	265
CRW_00140	SSU_rRNA_bacteria links to Rfam database...	0.38	0.38	0.38	176	1135818	299	27	257	15	287
CRW_00141	SSU_rRNA_bacteria links to Rfam database...	0.53	0.53	0.54	253	1201553	246	34	185	27	223
CRW_00150	SSU_rRNA_bacteria links to Rfam database...	0.45	0.44	0.45	204	1152472	262	26	219	17	262
CRW_00152	SSU_rRNA_bacteria links to Rfam database...	0.53	0.52	0.54	246	1179962	231	33	175	23	225
CRW_00166	SSU_rRNA_bacteria links to Rfam database...	0.40	0.40	0.39	188	1190720	309	32	256	21	280
CRW_00173	SSU_rRNA_bacteria links to Rfam database...	0.28	0.28	0.28	125	1082214	333	31	286	16	320
CRW_00177	SSU_rRNA_bacteria links to Rfam database...	0.49	0.48	0.50	226	1178426	251	26	202	23	247
CRW_00196	SSU_rRNA_bacteria links to Rfam database...	0.45	0.46	0.44	219	1207740	296	42	234	20	256
CRW_00230	SSU_rRNA_bacteria links to Rfam database...	0.53	0.52	0.54	247	1198465	241	32	182	27	231
CRW_00245	SSU_rRNA_bacteria links to Rfam database...	0.37	0.37	0.37	167	1105882	297	32	247	18	286
CRW_00248	SSU_rRNA_bacteria links to Rfam database...	0.49	0.49	0.48	238	1218645	286	36	222	28	246
CRW_00250	SSU_rRNA_bacteria links to Rfam database...	0.37	0.38	0.37	181	1198432	321	48	265	8	297
CRW_00256	SSU_rRNA_bacteria links to Rfam database...	0.39	0.39	0.40	183	1192281	294	41	235	18	285
CRW_00270	SSU_rRNA_bacteria links to Rfam database...	0.54	0.54	0.54	245	1111832	232	27	182	23	210
CRW_00271	SSU_rRNA_bacteria links to Rfam database...	0.36	0.36	0.37	168	1122293	309	37	253	19	294
CRW_00273	SSU_rRNA_bacteria links to Rfam database...	0.52	0.52	0.52	233	1085151	238	41	176	21	213
CRW_00275	SSU_rRNA_bacteria links to Rfam database...	0.59	0.59	0.59	271	1114809	212	28	163	21	186
CRW_00277	SSU_rRNA_bacteria links to Rfam database...	0.32	0.32	0.32	144	1110348	313	38	265	10	309
CRW_00280	SSU_rRNA_bacteria links to Rfam database...	0.33	0.33	0.32	151	1117794	327	43	272	12	302
CRW_00281	SSU_rRNA_bacteria links to Rfam database...	0.53	0.52	0.53	243	1144885	238	27	186	25	221
CRW_00283	SSU_rRNA_bacteria links to Rfam database...	0.32	0.32	0.33	140	1015595	312	49	241	22	292
CRW_00289	SSU_rRNA_bacteria links to Rfam database...	0.51	0.50	0.52	237	1189193	251	38	185	28	239
CRW_00292	SSU_rRNA_bacteria links to Rfam database...	0.41	0.39	0.42	181	1123819	271	41	209	21	280
CRW_00306	SSU_rRNA_eukarya links to Rfam database...	0.09	0.09	0.08	43	1445337	532	80	390	62	419
CRW_00366	SSU_rRNA_eukarya links to Rfam database...	0.27	0.29	0.25	138	1579211	437	87	317	33	344
CRW_00371	SSU_rRNA_eukarya links to Rfam database...	0.34	0.35	0.33	173	1611383	414	61	293	60	323
CRW_00379	SSU_rRNA_eukarya links to Rfam database...	0.44	0.45	0.44	241	2126401	411	60	251	100	293
CRW_00411	SSU_rRNA_eukarya links to Rfam database...	0.35	0.36	0.34	177	1614982	392	60	284	48	319
CRW_00414	SSU_rRNA_eukarya links to Rfam database...	0.29	0.31	0.28	152	1665688	448	68	317	63	343
CRW_00466	SSU_rRNA_bacteria links to Rfam database...	0.57	0.56	0.57	257	1116315	221	28	165	28	201
CRW_00589	SSU_rRNA_bacteria links to Rfam database...	0.30	0.30	0.31	133	1094029	317	35	263	19	312
CRW_00590	SSU_rRNA_bacteria links to Rfam database...	0.42	0.42	0.42	191	1119306	279	34	225	20	261
CRW_00591	SSU_rRNA_bacteria links to Rfam database...	0.50	0.50	0.50	222	1098458	256	20	203	33	224
CRW_00759	SSU_rRNA_eukarya links to Rfam database...	0.31	0.32	0.29	156	1636612	443	67	310	66	325
CRW_00763	SSU_rRNA_bacteria links to Rfam database...	0.20	0.20	0.20	90	1215568	391	45	317	29	356
CRW_00778	SSU_rRNA_bacteria links to Rfam database...	0.27	0.28	0.26	107	1201617	345	45	256	44	277
CRW_00789	SSU_rRNA_bacteria links to Rfam database...	0.39	0.38	0.39	172	1137342	303	31	241	31	275
CRW_00795	SSU_rRNA_bacteria links to Rfam database...	0.32	0.33	0.30	130	1152494	342	43	254	45	264
CRW_00849	SSU_rRNA_bacteria links to Rfam database...	0.53	0.53	0.52	250	1117779	255	29	202	24	220
CRW_00997	SSU_rRNA_bacteria links to Rfam database...	0.37	0.38	0.37	175	1135806	315	41	256	18	289
CRW_01153	SSU_rRNA_eukarya links to Rfam database...	0.36	0.37	0.35	187	1605990	391	60	291	40	316
CRW_01171	SSU_rRNA_eukarya links to Rfam database...	0.28	0.28	0.27	143	1593476	430	75	311	44	363
CRW_01343	SSU_rRNA_archaea links to Rfam database...	0.37	0.36	0.38	158	977486	272	36	221	15	276
PDB_00703	SSU_rRNA_bacteria links to Rfam database...	0.48	0.46	0.50	229	1073385	256	28	203	25	266
PDB_00854	SSU_rRNA_bacteria links to Rfam database...	0.46	0.46	0.46	246	1500244	334	36	252	46	289
PDB_01088	SSU_rRNA_bacteria links to Rfam database...	0.34	0.33	0.34	180	1470946	368	36	308	24	367
PDB_01103	SSU_rRNA_bacteria links to Rfam database...	0.44	0.44	0.44	245	1605966	343	42	275	26	317
PDB_01105	SSU_rRNA_bacteria links to Rfam database...	0.46	0.45	0.47	245	1433450	306	32	244	30	295
PDB_01120	SSU_rRNA_bacteria links to Rfam database...	0.31	0.30	0.33	158	1204643	339	37	290	12	369
PDB_01273	SSU_rRNA_bacteria links to Rfam database...	0.38	0.38	0.39	186	1117784	320	28	262	30	305

^top

Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.

Table of contents:

Overview

Performance plots

Performance of RSpredict(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RSpredict(seed)

2. Individual counts for RSpredict(seed) [ download as .csv ]

Performance of Fold - scored lower in this pairwise comparison

1. Total counts & total scores for Fold

2. Individual counts for Fold [ download as .csv ]